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| 1 | Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model显示文摘AIM: To explore the effect of platelet-rich plasma on protein expression patterns of transforming growth factor-beta1(TGF-β1) in cartilage following autologous osteochondral transplantation(AOT) in a rabbit knee cartilage defect model.METHODS: Twelve New Zealand white rabbits received bilateral AOT. In each rabbit, one knee was randomized to receive an autologous platelet rich plasma(PRP) injection and the contralateral knee received saline injection. Rabbits were euthanized at 3, 6 and 12 wk post-operatively. Articular cartilage sections were stained with TGF-β1 antibody. Histological regions of interest(ROI)(left, right and center of the autologous grafts interfaces) were evaluated using Meta Morph. Percentage of chondrocytes positive for TGF-β1 was then assessed.RESULTS: Percentage of chondrocytes positive for TGF-β1 was higher in PRP treated knees for selected ROIs(left; P = 0.03, center; P = 0.05) compared to control and was also higher in the PRP group at each post-operative time point(P = 6.6 × 10^(-4), 3.1 × 10^(-4) and 7.3 × 10^(-3) for 3, 6 and 12 wk, respectively). TGF-β1 expression was higher in chondrocytes of PRP-treated knees(36% ± 29% vs 15% ± 18%)(P = 1.8 × 10^(-6)) overall for each post-operative time point and ROI. CONCLUSION: Articular cartilage of rabbits treated with AOT and PRP exhibit increased TGF-β1 expression compared to those treated with AOT and saline. Our findings suggest that adjunctive PRP may increase TGF-β1 expression, which may play a role in the chondrogenic effect of PRP in vivo. | Lorraine A Boakye Keir A Ross John M Pinski Niall A Smyth Amgad M Haleem Charles P Hannon Lisa A Fortier John G Kennedy | 2015 | World Journal of Orthopedics2015，6，11： | 7 |
| 2 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet . 2012 (9859)2012，，9859： | 7 |
| 3 | Football injuries of the ankle: A review of injury mechanisms, diagnosis and management显示文摘Football is the most popular sport worldwide and is associated with a high injury rate, most of which are the result of trauma from player contact. Ankle injuries are among the most commonly diagnosed injuries in the game. The result is reduced physical activity and endurance levels, lost game time, and considerable medical cost. Sports medicine professionals must employ the correct diagnostic tools and effective treatments and rehabilitation protocols to minimize the impact of these injuries on the player. This review examines the diagnosis, treatment, and postoperative rehabilitation for common football injuries of the ankle based on the clinical evidence provided in the current literature. | Raymond J Walls Keir A Ross Ethan J Fraser Christopher W Hodgkins Niall A Smyth Christopher J Egan James Calder John G Kennedy | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 4 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet2012，，9859： | 5 |
| 5 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 6 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004，7，4： | 3 |
| 7 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 8 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | 2012 (9859)2012，，9859： | 2 |
| 9 | Simultaneous determination of inorganic anions, organic acids, amino acids and carbo- hydrates by capillary electrophoresis显示文摘 | SOGA T ROSS G A | 1999 | J Chromatogr A1999，837，： | 1 |
| 10 | Forms and functions of CD44 显示文摘 | BORLAND G ROSS J A GUY K | 1998 | Immunology1998，93，： | 1 |
| 11 | Information Hiding-A Survey显示文摘 | Fabien A P Petitcolas Ross J Anderson Markus G Kuhn | 1999 | Prpceedings of the IEEE1999，87，7： | 1 |
| 12 | AMPK:a nutrient and energy sensor that maintains energy homeostasis显示文摘 | HARDIE D G ROSS F A HAWLEY S A | 2012 | Nature Reviews Molecular Cell Biology2012，13，4： | 1 |
| 13 | Information hiding: a survey显示文摘 | FABIEN A P P ROSS J A MARKUS G K | 1999 | Proceedings of the IEEE Special Issue on Protection of Multimedia Content1999，87，7： | 1 |
| 14 | Forms and functions of CD44显示文摘 | BORLAND G ROSS J A GUY K | 1998 | Immunology1998，93，： | 1 |
| 15 | Cathelicidins: Microbicidal activity, mechanisms of action, and roles in in- nate immunity显示文摘 | Ramanathan B Davis E G Ross C R et a l | 2002 | Microb Infect2002，4，： | 1 |
| 16 | Comparison of agerelated differences in expression of phospholipid hydroperoxide glutathione peroxidase mRNA and activity in various tissues of pigs显示文摘 | Lei X G Ross D A Roneker K R | 1997 | Comp Biochem Physiol B Biochem Mol Biol1997，117，1： | 1 |
| 17 | Testing a key assumption of wildlife buffer zones:is flight initiation distance a species trait显示文摘 | Blumstein DT Anthony LL Harcourt A Ross G | | 0，，： | 1 |
| 18 | Physicochemical properties of Australian flours influencing the texture of yellow alkaline noodles显示文摘 | ROSS A S QUAIL K J CROSBIE G B | 1997 | Cereal Chem1997，74，： | 1 |
| 19 | Information Hiding-A Survey显示文摘 | Ross J Anderson Markus G Kuhn | 1999 | Proceedings of the IEEE Special Issue on Protection of Multimedia Content1999，87，7： | 1 |
| 20 | Photoperiod regulates arcuate nucleus POMC, AGRP, and Leptin receptor mRNA in siberian hamster hypothalamus显示文摘 | Mercer J G Moa K M Ross A W | 2000 | American Journal Physiology Regulatory Integrative and Comparative Physiology2000，278，1： | 1 |
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