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| 1 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004，7，4： | 3 |
| 2 | WR-2721 (amifostine) infusion in patients with Ewing’s sarcoma receiving ifosfamide and cyclophosphamide with mesna: drug and thiol levels in plasma and blood cells, a Pediatric Oncology Group study显示文摘 | Abdul-Kader Souid Robert C. Fahey Ronald L. Dubowy Gerald L. Newton Mark L. Bernstein | 1999 | Cancer Chemotherapy and Pharmacology1999，，6： | 1 |
| 3 | The history of awake craniotomy for brain tumor and its spread into Asia显示文摘 | Julius July Pirjo Manninen Jacob Lai Zhenhai Yao Mark Bernstein | 2009 | Surgical Neu- rology2009，71，5： | 1 |
| 4 | A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium显示文摘 | Alexandra P. Zorzi Mark Bernstein Yvan Samson Donna A. Wall Sunil Desai Darcy Nicksy Nancy Wainman Elizabeth Eisenhauer Sylvain Baruchel | 2013 | Pediatr Blood Cancer2013，，11： | 1 |
| 5 | The clean air act's sulfur dioxide emissions market: estimating the costs of regulatory and legislative intervention显示文摘 | Winebrake James J Alexander E Farrell Mark A Bernstein | 1995 | Resource and Energy Economics1995，17，： | 1 |
| 6 | HER‐2 expression is not prognostic in osteosarcoma; a Children’s Oncology Group prospective biology study显示文摘 | Sarah Gorlick Donald A. Barkauskas Mark Krailo Sajida Piperdi Rebecca Sowers Jonathan Gill David Geller R. Lor Randall Katherine Janeway Cindy Schwartz Holcombe Grier Paul A. Meyers Richard Gorlick Mark Bernstein Neyssa Marina | 2014 | Pediatr Blood Cancer2014，，9： | 1 |
| 7 | β-Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency——A Randomized,Placebo-Controlled,and Double-Blinded Trial显示文摘Objective:To test the hypothesis thatβ-glucan enhances protective qi(PQi),an important Chinese medicine(CM)concept which stipulates that a protective force circulates throughout the body surface and works as the first line of defense against'external pernicious influences'.Methods:A total of 138 participants with PQi deficiency(PQD)were randomized to receiveβ-glucan(200 mg daily)or placebo for 12 weeks.Participants’PQi status was assessed every 2 weeks via conventional diagnosis and a standardized protocol from which a PQD severity and risk score was derived.Indices of participants’immune and general health status were also monitored,including upper respiratory tract infection(URTI),saliva secretory Ig A(s Ig A),and self-reported measures of physical and mental health(PROMIS).Results:PQi status was not significantly different between theβ-glucan and placebo treatment groups at baseline but improved significantly in theβ-glucan(vs.placebo)group in a time-dependent manner.The intergroup differences[95%confidence interval(CI)]in severity score(scale:1-5),risk score(scale:0-1),and proportion of PQD participants(%)at finish line was 0.49(0.35-0.62),0.48(0.35-0.61),and 0.36(0.25-0.47),respectively.Additionally,β-glucan improved URTI symptom(scale:1-9)and PROMIS physical(scale:16.2-67.7)and mental(scale:21.2-67.6)scores by a magnitude(95%CI)of 1.0(0.21-1.86),5.7(2.33-9.07),and 3.0(-0.37-6.37),respectively,over placebo.Conclusions:β-Glucan ameliorates PQi in PQD individuals.By using stringent evidence-based methodologies,our study demonstrated that Western medicine-derived remedies,such asβ-glucan,can be employed to advance CM therapeutics.(Clinical Trial.Gov registry:NCT03782974) | WU Jun-rong CHENG Hao-jie SHI Jian-pin YIN Wei-dong WANG Jun OU Xuan-qiao CHEN Jin-li Ira Bernstein Mark Levy Rolando Maddela Robert Sinnott TIAN Jun-qiang | 2022 | Chinese Journal of Integrative Medicine2022，28，5： | 1 |
| 8 | ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia显示文摘 | Stephen G. Landt Georgi K. Marinov Anshul Kundaje Pouya Kheradpour Florencia Pauli Serafim Batzoglou Bradley E. Bernstein Peter Bickel James B. Brown Philip Cayting Yiwen Chen Gilberto DeSalvo Charles Epstein Katherine I. Fisher-Aylor Ghia Euskirchen Mark | 2012 | Genome Research2012，，9： | 1 |
| 9 | Cerebral Hyperperfusion after Carotid Endarterectomy: A Cause of Cerebral Hemorrhage显示文摘 | Mark Bernstein Ross J. F. Fleming John H. N. Deck | 1984 | Neurosurgery1984，，1： | 1 |
| 10 | Can breast and cervical cancer screening visits be used to enhance colorectal cancer screening?显示文摘 | Ruth C. Carlos A. Mark Fendrick James Ellis Steven J. Bernstein | 2004 | Journal of the American College of Radiology2004，，： | 1 |
| 11 | Momparler,preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine)and histone deacetylation(trichostatin A,depsipeptide)in combination against myeloid leukemic cells显示文摘 | Sepideh Shaker Mark Bernstein Louise F | 2003 | Leuk Res2003，27，： | 1 |
| 12 | Using Dabigatran in Patients With Stroke: A Practical Guide for Clinicians显示文摘 | Mark J. Alberts Richard A. Bernstein Gerald V. Naccarelli David A. Garcia | 2012 | Stroke2012，，1： | 1 |
| 13 | Correlates of circulating C-reactive protein and serum amyloid A concentrations in breast cancer survivors显示文摘 | Brandon L. Pierce Marian L. Neuhouser Mark H. Wener Leslie Bernstein Richard N. Baumgartner Rachel Ballard-Barbash Frank D. Gilliland Kathy B. Baumgartner Bess Sorensen Anne McTiernan Cornelia M. Ulrich | 2009 | Breast Cancer Research and Treatment2009，，1： | 1 |
| 14 | Friends without Favoritism显示文摘 | Mark Bernstein | 2007 | The Journal of Value Inquiry2007，，1： | 1 |
| 15 | Adenomyosis and endometriosis in the California Teachers Study显示文摘 | Claire Templeman Sarah F. Marshall Giske Ursin Pamela L. Horn-Ross Christina A. Clarke Mark Allen Dennis Deapen Argyrios Ziogas Peggy Reynolds Rosemary Cress Hoda Anton-Culver Dee West Ronald K. Ross Leslie Bernstein | 2008 | Fertility and Sterility2008，，2： | 1 |
| 16 | The cyanohydridoborate anion as a selective reducing agent显示文摘 | Richard F Borch Mark D Bernstein | 1993 | J Am Chem Soc1993，115，7： | 1 |
| 17 | Xylocaine plus methylene blue vs methylene blue alone for mark in breast tissue preoperatively显示文摘 | MARK M BERNSTEIN R M WACK J P | 1998 | Nihon Kokyuki Gakkai Zasshi1998，36，2： | 1 |
| 18 | Sports stadium boondoggle显示文摘 | MARK F BERNSTEIN | 1998 | Public Interest1998，，： | 1 |
| 19 | Proof-of-Concept and Feasibility Study to Evaluate the Effect of β-Glucan on Protective Qi Deficiency in Adults显示文摘Objective:To preliminarily explore the potential effect ofβ-glucan on Chinese medicine(CM)concept protective qi deficiency(PQD),and the methodology for future definitive studies.Methods:To have a standardized assessment of PQD,a list of 13 potentially PQD-relevant parameters were firstly created,each with defined quantitative or categorial scales.Using the data from 37 participants with(21 cases)or without(16 cases)PQD,multivariate logistic modeling was conducted to create a preliminary diagnostic PQD risk score.Subsequently,21 participants diagnosed with PQD were treated withβ-glucan in a dose of 200 mg/day for 8 weeks.Data were collected for trial acceptability measures(rate of recruitment,withdrawal,and compliance),and the participants were assessed for PQD status at baseline and every 2 weeks thereafter.Results:The preliminary logistic model consisted of 3 parameters(low voice and apathy,aversion to wind and cold,and Cun pulse).The resulting risk score demonstrated a degree of PQD-predicting accuracy that,as evaluated by statistical(discrimination and classification)methods,was higher than those obtained from any of the individual candidate parameters.The 21 PQD participants treated withβ-glucan demonstrated good receptibility and a time-dependent improvement in PQD status as evidenced by the decrease of PQD participant to 9.5%at the end of study.Conclusions:This study demonstrated the effect of proof-of-concept ofβ-glucan on improving PQD and the proof-of-concept of a multivariate-model-derived diagnostic PQD risk score.It also indicated feasibility for future definitive studies.Studies like this embody an innovative approach that uses therapies derived from the mainstream biomedicine to enrich therapeutics guided by CM principle.(Trial registration No.NCT03829228). | Mark Levy WU Jun-rong SHI Jian-pin CHENG Hao-jie QU Xuan-qiao Ira Bernstein Robert Sinnott TIAN Jun-qiang | 2021 | Chinese Journal of Integrative Medicine2021，27，9： | 0 |
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