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    题名 作者 年代 出处 被引量
1Proteomic analysis of the probiotic Lactobacillus reuteri CRL1098 reveals novel tolerance biomarkers to bile acid-induced stresss显示文摘Ana Y B Graciela F V Raúl R 2015Food Research International2015,77,3:1
2Aquaporins:Their role in cholestatic liver disease显示文摘This review focuses on current knowledge on hepato-cyte aquaporins(AQPs)and their significance in bile formation and cholestasis.Canalicular bile secretion results from a combined interaction of several solute transporters and AQP water channels that facilitate water flow in response to the osmotic gradients created. During choleresis,hepatocytes rapidly increase their canalicular membrane water permeability by modulating the abundance of AQP8.The question was raised as to whether the opposite process,i.e.a decreased canalicular AQP8 expression would contribute to the development of cholestasis.Studies in several experimental models of cholestasis,such as extrahepatic obstructive cholestasis,estrogen-induced cholestasis, and sepsis-induced cholestasis demonstrated that the protein expression of hepatocyte AQP8 was impaired. In addition,biophysical studies in canalicular plasma membranes revealed decreased water permeability associated with AQP8 protein downregulation.The combined alteration in hepatocyte solute transporters and AQP8 would hamper the efficient coupling of osmotic gradients and canalicular water flow.Thus cholestasis may result from a mutual occurrence of impaired solute transport and decreased water permeability.Guillermo L Lehmann Maria C Larocca Leandro R Soria Raúl A Marinelli 2008World Journal of Gastroenterology2008,14,46:8
3Tau oligomers and aggregation in Alzheimer’s disease显示文摘Marco A.Meraz‐Ríos Karla I.Lira‐De León VictoriaCampos‐Pe?a Martha A.De Anda‐Hernández RaúlMena‐López 2010Journal of Neurochemistry2010,,6:1
4Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen显示文摘María J. Dus Santos Consuelo Carrillo Fernando Ardila Raúl D. Ríos Pascual Franzone María E. Piccone Andrés Wigdorovitz Manuel V. Borca 2004Vaccine2004,,15:1
5Novel electrode structure in a DBD reactor applied to the degradation of phenol in aqueous solution显示文摘Phenol degradation experimental results are presented in a similar wastewater aqueous solution using a non-thermal plasma reactor in a coaxial dielectric barrier discharge. The novelty of the work is that one of the electrodes of the reactor has the shape of a hollow screw which shows an enhanced efficiency compared with a traditional smooth structure. The experimentation was carried out with gas mixtures of 90% Ar–10% O_2, 80% Ar–20% O_2 and 0% Ar–100% O_2. After one hour of treatment the removal efficiency was 76%, 92%, and 97%, respectively, assessed with a gas chromatographic mass spectrometry technique. For both reactors used, the ozone concentration was measured. The screw electrode required less energy, for all gas mixtures, than the smooth electrode, to maintain the same ozone concentration. On the other hand, it was also observed that in both electrodes the electrical conductivity of the solution changed slightly from^0.0115 S m^(-1) up to ~0.0430 S m^(-1) after one hour of treatment. The advantages of using the hollow screw electrode structure compared with the smooth electrode were:(1) lower typical power consumption,(2) the generation of a uniform plasma throughout the reactor benefiting the phenol degradation,(3) a relatively lower temperature of the aqueous solution during the process, and(4) the plasma generation length is larger.Antonio MERCADO-CABRERA Rosendo PE?A-EGUILUZ Régulo LóPEZ-CALLEJAS Bethsabet JARAMILLO-SIERRA Raúl VALENCIA-ALVARADO Benjamín RODRíGUEZ-MéNDEZ Arturo E MU?OZ-CASTRO 2017Plasma Science and Technology2017,19,7:1
6Induction of a Protective Antibody Response to Foot and Mouth Disease Virus in Mice Following Oral or Parenteral Immunization with Alfalfa Transgenic Plants Expressing the Viral Structural Protein VP1显示文摘Andrés Wigdorovitz Consuelo Carrillo Mar??a J. Dus Santos Karina Trono Andrea Peralta Mar??a C. Gómez Raúl D. R??os Pascual M. Franzone Ana M. Sadir José M. Escribano Manuel V. Borca 1999Virology1999,,2:1
7Phenotypic characterization of idiosyncratic drug‐induced liver injury: The influence of age and sex显示文摘M. Isabel Lucena Raúl J. Andrade Neil Kaplowitz Miren García‐Cortes M. Carmen Fernández Manuel Romero‐Gomez Miguel Bruguera Hacibe Hallal Mercedes Robles‐Diaz Jose F. Rodriguez‐González Jose Maria Navarro Javier Salmeron Pedro Martinez‐Odriozola Ramón Pér 2009Hepatology2009,,:1
8Low serum levels of ghrelin are associated with gallstone disease显示文摘瞄准:在胆石疾病探索 ghrelin 的角色。方法:我们在 150 个题目,执行了代表性的研究 38 与胆石(盒子) 和 112 控制。我们也各在二十件胆囊样品做了即时 PCR-RT 研究。身体集体索引(BMI ) ,浆液胰岛素, ghrelin,和浆液类脂化合物被测量。逻辑回归分析(univariate 并且多变量) 被进行估计与浆液 ghrelin 集中联系的胆石疾病的概率。结果:盒子与在性分发的控制统计上不同(P = 0.01 ) ,年龄(53 对 44 年, P = 0.002 ) , BMI (28 对 25;P = 0.004 ) ,并且葡萄糖(5.26 对 4.98 mmol/L;P = 0.05 ) 。没有新陈代谢的症候群,在第三 tercile 上面的 ghrelin 浆液层次的流行在题目是更低的(P < 0.05 ) 。在里面一多,变量当模特儿,当 ghrelin 价值比中部的价值高时,我们发现了保护的效果(或 = 0.27, 95%CI 0.09-0.82, P = 0.02 ) 。二十(20%) 胆囊标本表示了 ghrelin mRNA。结论:浆液 ghrelin 集中与 GD 的保护的效果被联系。Nahum Méndez-Sánchez Guadalupe Ponciano-Rodríguez Luisa Bermejo-Martínez Antonio R Villa Norberto C Chávez-Tapia Daniel Zamora-Valdés Raúl Pichardo-Bahena Blanca Barredo-Prieto Martha H Uribe-Ramos Martha H Ramos Héctor A Baptista-González Misael Uribe 2006World Journal of Gastroenterology2006,12,19:0
9Atmospheric-pressure dielectric barrier discharge generation by a full-bridge flying capacitor multilevel inverter显示文摘A new configuration of a resonant full-bridge flying capacitor multicell inverter has been designed and constructed with the aim of achieving an extended output voltage frequency range with low harmonic distortion and reduced semiconductor commutation losses. This configuration was tested as a power supply for two different coaxial dielectric barrier discharge reactors, one of them employed for electric characterization and the other one for inorganic compound elimination in an aqueous solution. Two different gas mixtures, 90% Ar–10% O_2 and80% Ar–20% O_2, were individually supplied during the experiments; the results showed a highefficiency removal of meta-cresol(m-cresol) to the order of 98%, which was obtained by adding more oxygen to the plasma gas mixture.Rosendo PE?A-EGUILUZ José A LóPEZ-FERNáNDEZ Antonio MERCADO-CABRERA Bethsabet JARAMILLO-SIERRA Régulo LóPEZ-CALLEJAS Benjamín RODRíGUEZ-MéNDEZ Raúl VALENCIA-ALVARADO Allan A FLORES-FUENTES Arturo E MU?OZ-CASTRO 2017Plasma Science and Technology2017,19,7:0
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