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| 1 | Rifaximin,but not growth factor 1,reduces brain edema in cirrhotic rats显示文摘AIM:To compare rifaximin and insulin-like growth factor(IGF)-1 treatment of hyperammonemia and brain edema in cirrhotic rats with portal occlusion.METHODS:Rats with CCl4-induced cirrhosis with ascites plus portal vein occlusion and controls were randomized into six groups:Cirrhosis;Cirrhosis + IGF-1;Cirrhosis + rifaximin;Controls;Controls + IGF-1;and Controls + rifaximin.An oral glutamine-challenge test was performed,and plasma and cerebral ammonia,glucose,bilirubin,transaminases,endotoxemia,brain water content and ileocecal cultures were measured and liver histology was assessed.RESULTS:Rifaximin treatment significantly reduced bacterial overgrowth and endotoxemia compared with cirrhosis groups,and improved some liver function parameters(bilirubin,alanine aminotransferase and aspartate aminotransferase).These effects were associated with a significant reduction in cerebral water content.Blood and cerebral ammonia levels,and area-underthe-curve values for oral glutamine-challenge tests were similar in rifaximin-treated cirrhotic rats and control group animals.By contrast,IGF-1 administration failed to improve most alterations observed in cirrhosis.CONCLUSION:By reducing gut bacterial overgrowth,only rifaximin was capable of normalizing plasma and brain ammonia and thereby abolishing low-grade brain edema,alterations associated with hepatic encephalopathy. | Gemmaòdena Mireia Miquel Anna Serafín Amparo Galan Rosa Morillas Ramon Planas Ramon Bartolí | 2012 | World Journal of Gastroenterology2012，18，17： | 6 |
| 2 | The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club显示文摘 | Kevin P. Moore Florence Wong Pere Gines Mauro Bernardi Andreas Ochs Francesco Salerno Paolo Angeli Michael Porayko Richard Moreau Guadelupe Garcia-Tsao Wladimiro Jimenez Ramon Planas Vicente Arroyo | 2003 | Hepatology2003，，1： | 4 |
| 3 | Tools for the diagnosis of hepatitis C virus infection and hepatic fibrosis staging显示文摘Hepatitis C virus(HCV)infection represents a major public health issue.Hepatitis C can be cured bytherapy,but many infected individuals are unaware of their status.Effective HCV screening,fast diagnosis and characterization,and hepatic fibrosis staging are highly relevant for controlling transmission,treating infected patients and,consequently,avoiding end-stage liver disease.Exposure to HCV can be determined with high sensitivity and specificity with currently available third generation serology assays.Additionally,the use of point-of-care tests can increase HCV screening opportunities.However,active HCV infection must be confirmed by direct diagnosis methods.Additionally,HCV genotyping is required prior to starting any treatment.Increasingly,high-volume clinical laboratories use different types of automated platforms,which have simplified sample processing,reduced hands-on-time,minimized contamination risks and human error and ensured full traceability of results.Significant advances have also been made in the field of fibrosis stage assessment with the development of non-invasive methods,such as imaging techniques and serum-based tests.However,no single test is currently available that is able to completely replace liver biopsy.This review focuses on approved commercial tools used to diagnose HCV infection and the recommended hepatic fibrosis staging tests. | Verónica Saludes Victoria González Ramon Planas Lurdes Matas Vicente Ausina Elisa Martró | 2014 | World Journal of Gastroenterology2014，20，13： | 4 |
| 4 | Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis显示文摘 | Cristina Ripoll Roberto J. Groszmann Guadalupe Garcia-Tsao Jaime Bosch Norman Grace Andrew Burroughs Ramon Planas Angels Escorsell Juan Carlos Garcia-Pagan Robert Makuch David Patch Daniel S. Matloff | 2009 | Journal of Hepatology2009，，5： | 3 |
| 5 | <ce:link locator='fx1'/> Hepatic Venous Pressure Gradient Predicts Clinical Decompensation in Patients With Compensated Cirrhosis显示文摘 | Cristina Ripoll Roberto Groszmann Guadalupe Garcia–Tsao Norman Grace Andrew Burroughs Ramon Planas Angels Escorsell Juan Carlos Garcia–Pagan Robert Makuch David Patch Daniel S. Matloff Jaime Bosch | 2007 | Gastroenterology2007，，2： | 2 |
| 6 | Hepatic Venous Pressure Gradient Predicts Clinical Decompensation in Patients With Compensated Cirrhosis显示文摘 | Cristina Ripoll Roberto Groszmann Guadalupe Garcia–Tsao Norman Grace Andrew Burroughs Ramon Planas Angels Escorsell Juan Carlos Garcia–Pagan Robert Makuch David Patch Daniel S. Matloff Jaime Bosch | 2007 | Gastroenterology2007，，： | 2 |
| 7 | Diagnosis, treatment and prophylaxis of spontaneous bacterial peritonitis: a consensus document显示文摘 | Antoni Rimola Guadalupe García-Tsao Miquel Navasa Laura J.V. Piddock Ramon Planas Brigitte Bernard John M. Inadomi | 2000 | Journal of Hepatology2000，，1： | 2 |
| 8 | Long-term Clinical Course of Decompensated Alcoholic Cirrhosis: A Prospective Study of 165 Patients显示文摘 | Marco Antonio Alvarez Isabel Cirera Ricard Solà Ana Bargalló Rosa Maria Morillas Ramon Planas | 2011 | Journal of Clinical Gastroenterology2011，，10： | 1 |
| 9 | The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club显示文摘 | Kevin P. Moore Florence Wong Pere Gines Mauro Bernardi Andreas Ochs Francesco Salerno Paolo Angeli Michael Porayko Richard Moreau Guadelupe Garcia-Tsao Wladimiro Jimenez Ramon Planas Vicente Arroyo | 2003 | Hepatology2003，，1： | 1 |
| 10 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 11 | Performance of an ultrasonic ranging sensor in apple tree canopies 显示文摘 | Alexandre Escola Santiago Planas Joan Ramon Rosell | 2011 | Sensors2011，11，3： | 1 |
| 12 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 13 | A tractor-mounted scanning LIDAR for the non-destructive measurement of vegetative volume and surface area of tree-row plantations: A comparison with conventional destructive measurements显示文摘 | Joan Ramon Rosell Polo Ricardo Sanz Jordi Llorens Jaume Arnó Alexandre Escolà Manel Ribes-Dasi Joan Masip Ferran Camp Felip Gràcia Francesc Solanelles Tomàs Pallejà Luis Val Santiago Planas Emilio Gil Jordi Palacín | 2008 | Biosystems Engineering2008，，2： | 1 |
| 14 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 15 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 16 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 17 | Hepatic Venous Pressure Gradient Predicts Clinical Decompensation in Patients With Compensated Cirrhosis显示文摘 | Cristina Ripoll Roberto Groszmann Guadalupe Garcia–Tsao Norman Grace Andrew Burroughs Ramon Planas Angels Escorsell Juan Carlos Garcia–Pagan Robert Makuch David Patch Daniel S. Matloff Jaime Bosch | 2007 | Gastroenterology2007，，2： | 1 |
| 18 | Natural history of decompensated hepatitis C virus-related cirrhosis. A study of 200 patients显示文摘 | Ramon Planas Belén Ballesté Marco Antonio álvarez Monica Rivera Silvia Montoliu Josep Anton Galeras Justiniano Santos Susanna Coll Rosa Maria Morillas Ricard Solà | 2004 | Journal of Hepatology2004，，5： | 1 |
| 19 | Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial显示文摘 | Antoni Mas Juan Rodés Lourdes Sunyer Lu??s Rodrigo Ramon Planas Victor Vargas Llu??s Castells Dolores Rodr??guez-Mart??nez Conrado Fernández-Rodr??guez Ignasi Coll Albert Pardo | 2002 | Journal of Hepatology2002，，1： | 1 |
| 20 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
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