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| 1 | Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis显示文摘Wnt/ 尾 - catenin 调整与肿瘤有关的细胞的功能开始和前进,房间增长,区别,幸存,和粘附。尾 -Catenin 独立的 Wnt 小径被建议了调整房间极性和移植,包括转移。在这评论,我们在肿瘤前进讨论 catenin 依赖的尾 - 和独立人士发信号小径的可能的角色,与他们 Rho 家庭 GTPases,改变的细胞骨架,和与房间房间粘附和 cilia/ciliogenesis 的关系的规定上的一个重音。 | Shih-Lei Lai Andy J Chien Randall T Moon | 2009 | Cell Research2009，19，5： | 15 |
| 2 | Update on the natural history of intracranial atherosclerotic disease: A critical review显示文摘Intracranial atherosclerotic disease (ICAD) contributes to a significant number of ischemic strokes. There is debate in the recent literature concerning the impact of the location of stenosis in ICAD on outcome. Some reports have suggested that disease processes and outcomes vary by vessel location, potentially altering the natural history and indications for intervention. Here we have performed a comprehensive, critical review of the natural history of ICAD by vessel in an attempt to assess the differences in disease specific to each of the vascular territories. Our assessment concludes that only minor differences exist between patients with different vessels affected in vessel-specific ICAD. We have found that middle cerebral artery disease confers a lower mortality than vessel-specific ICAD in other intracranial vessels, asymptomatic disease follows a more benign course than symptomatic disease, andthat plaque progression or the detection of microemboli on transcranial Doppler may predict poor outcome. Given the expanding indications for treatment of ICAD and rapidly developing endovascular techniques to confront this disease, a thorough understanding of the natural history of ICAD aids the interventional neuroradiologist in determining when to treat and how to predict outcome in this patient population. | Ricardo J Komotar Christopher P Kellner Daniel M Raper Dorothea Strozyk Randall T Higashida Philip M Meyers | 2010 | World Journal of Radiology2010，2，5： | 8 |
| 3 | Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Harald Hampel José Luis Molinuevo Kaj Blennow Steven T DeKosky Serge Gauthier Dennis Selkoe Randall Bateman Stefano Cappa Sebastian Crutch Sebastiaan Engelborghs Giovanni B Frisoni Nick C Fox Douglas Galasko Ma | 2014 | Lancet Neurology2014，，6： | 7 |
| 4 | Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P <
0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P <
0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P <
0.05 ) , hMLH1 吸烟者(P <
0.1 ) 并且 hMSH2 吸烟者(P <
0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P <
0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P <
0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。 | Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy | 2006 | World Journal of Gastroenterology2006，12，28： | 5 |
| 5 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 6 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 7 | MRI-based measurement of hippocampal volume in patients with ccrnhat- related posttraumatic stress disorder显示文摘 | BREMNER J D RANDALL P SCOTT T M | 1995 | Am J Psychiatry1995，152，7： | 2 |
| 8 | Evaluation of a practice guideline for noninvasive positive pressure ventilation for acute respiratory failure显示文摘 | Sinuff T Cook Dj Randall J | 2003 | Chest2003，123，6： | 1 |
| 9 | Application of Spectral Kurtosis for Detection of a Tooth Crack in the Planetary Gear of a Wind Turbine显示文摘 | Barszcz T Randall R | 2009 | Mechanical Systems and Signal Processing2009，23，： | 1 |
| 10 | Reversible adduct formation of trimethylgallium and trimethylindium with am monia显示文摘 | Randall Creighton J George T Wang | 2005 | J Phys Chem A2005，109，1： | 1 |
| 11 | Phase relations and dielectric properties in the Bi2O3-ZnO-Ta2O5 system显示文摘 | YOUN H J SOGABE T RANDALL C A | 2001 | J Am Ceram Soc2001，84，11： | 1 |
| 12 | Nitrate versus Oxygen Respiration in the Activated Sludge Process显示文摘 | McClintock S A Sherrard J H Novak J T Randall C W | 1988 | Journal WPCF1988，60，3： | 1 |
| 13 | Kinetics of metal or- ganic-ammonia adduct decomposition: Implications for group-III nitride MOCVD显示文摘 | Randall Creighton J George T Wang | 2005 | J Phys Chem A2005，109，10： | 1 |
| 14 | Triplet repeat mutations:amplication within pedigrees generates three human diseases 显示文摘 | | 1993 | JAMA1993，269，： | 1 |
| 15 | Evaluation of a practice guideline for noninvasive positive pressure ventilation for acute respiratory failure显示文摘 | Sinuf T Cook DJ Randall J | 2003 | Chest2003，123，： | 1 |
| 16 | Microwave processing of electroceramic materials and devices显示文摘 | Fang C Y Randal C A Lanagan M T | 2009 | Journal of Electroceramics2009，22，： | 1 |
| 17 | Laboratory factors influencing slim tube test results显示文摘 | RANDALL T E BENNION D B | 1989 | JCPT1989，，7： | 1 |
| 18 | Intracellular localization and Intra- cellular hereogeneity of the human DNA repair protein 06 - methylguanine - DNA methyltransferase 显示文摘 | Belanich M Randall T Pastor MA | 1996 | Cance:r Chemother Pharmacol1996，37，6： | 1 |
| 19 | Action of repeat -induced point mutation on both strands of a duplex and on tandem duplications of various sizes in Neurospora 显示文摘 | Watters M K Randall T A Margolin B S | 1999 | Genetics1999，153，2： | 1 |
| 20 | An empirical ex- amination of the decision to invest infulfillment capabilities: A study of Intemet retailers 显示文摘 | RANDALL T NETESSINE S RUDI N | 2006 | Management Science2006，52，4： | 1 |
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