|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 2 | Exercise induces rapid Increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle显示文摘 | REN J M SEMENKOVICH C F GULVE E A | 1994 | J Biol Chem1994，269，14： | 1 |
| 3 | Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole 显示文摘 | Pitkow L J Sharer C A Ren X Insel T R Terwilliger E F Young L J | 2001 | J Neurosci2001，21，18： | 1 |
| 4 | Urban climatic map studies: A review显示文摘 | Ren C Ng E Y Y Katzschner L | 2011 | Climatol2011，31，15： | 1 |
| 5 | Characterisation of copperoxide nanoparticles for antimicrobial applications 显示文摘 | Ren G G Hu D W Cheng E W C | 2009 | International Journal of Antimicrobial Agents2009，33，6： | 1 |
| 6 | Urban Climatic Map Studies:A Review显示文摘 | Ren C Ng E Katzschner L | | 0，，15： | 1 |
| 7 | Improving the wind environment in high-density cities by understanding urban morphology and surface roughness : A study in Hong Kong显示文摘 | Ng E Yuan C Chert L Ren C Fung J C H | 2011 | Landscape Urban Plan2011，101，1： | 1 |
| 8 | Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor(KIR)genes among Chinese,Malay,and Indian in Singapore显示文摘 | Lee Y C Chan S H Ren E C | 2008 | Immunogenetics2008，60，11： | 1 |
| 9 | PEM fuel cells for transportation and stationary power generation applications显示文摘 | Cleghorh S J C Ren X Springer T E | 1997 | International J Hydrogen Energy1997，22，12： | 1 |
| 10 | Expression of Epstein-Barr virus lyric gene BRLF1 in nasopharyngeal carcinoma: potential use in diagnosis显示文摘 | Feng P Ren E C Liu D | 2000 | Virology2000，81，10： | 1 |
| 11 | Control of photoresist properties: a Kalman filter based approach 显示文摘 | PALMER E REN W SPANOS C J | 1996 | IEEE Transactions on Semiconductor Manufacturing1996，9，2： | 1 |
| 12 | HLA-A2 allelle microvariants in nasopharyngeal carcinoma显示文摘 | Ren E C Law G G T Chan S H | 1995 | Int J Cancer1995，63，4： | 1 |
| 13 | NF-E2-related factor 2,a key inducer of antioxidant defenses,negatively regulates the CFTR transcription显示文摘 | René C Lopez E Claustres M | | 0，，13： | 1 |
| 14 | Ligand-induced conformational changes and a mechanism for domain closure in Aspergillus nidulans dehydroquinate synthase显示文摘 | Ren J Lamb H K | 2003 | J Mol Biol2003，327，： | 1 |
| 15 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 16 | MEME SUITE: tools for motif discovery and searching 显示文摘 | Bailey T L Boden M Buske F A Frith M Grant C E Clementi L Ren J Li W W Noble W S | 2009 | Nucleic Acids Research2009，37，： | 1 |
| 17 | Urban climatic map studies:a review显示文摘 | REN C NG E Y KATZSCHNER L | 2011 | International Journal of Climatology2011，31，15： | 1 |
| 18 | A new low-cost sensorless MPPT algorithmor small wind turbines显示文摘 | René Aubrée Fran(c)ois Auger Ping Dai | | 0，，： | 1 |
| 19 | Early results of laparoscopic biliopancreatic diversion with duodenal switch:a case series of 40 consecutive patients显示文摘 | Ren C J Patterson E Gagner M | 2000 | Obes Surg2000，10，6： | 1 |
| 20 | An allotriploid derived from a amphidiploid×diploid mating in Cucumis I : production, micropropagation and verification显示文摘 | CHEN J F LUO X D STAUB J E MARGARET M J QIAN C T ZHUANG F Y REN G | 2003 | Euphytica2003，131，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员