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| 1 | Infantile hepatic hemangioendothelioma:A clinicopathologic study in a Chinese population显示文摘AIM:To investigate whether the clinicopathologic features of infantile hemangioendothelioma(IHE) of the liver in a Chinese population are similar to the features observed in other races.METHODS:The clinical data,radiological findings,histopathological changes and outcome of 12 cases of IHE diagnosed by the Department of Pathology,West China Hospital over the last 10 years were analyzed retrospectively.Immunohistochemical studies were carried out using antibodies against CD31,CD34,Factor Ⅷ,cytokeratin 8 and cytokeratin 18.RESULTS:The 12 patients were aged from fetal to 5 years(three males and nine females).The tumor was presented with different clinical manifestations,mainly as an asymptomatic,palpable,upper abdominal mass,except for the two fetuses who were detected antena-tally by ultrasound.In one patient,this presentation was accompanied by an initial severe pneumothorax.No symptoms of congestive heart failure were present and neither congenital abnormalities nor vascular tumors in the skin or other organs were found.Laboratory abnormalities included leukocytosis(40%),anemia(60%),thrombocytosis(60%),hyperbilirubinemia(16.7%),abnormal liver function(50%) and increased α-fetoprotein(80%).Based on radiological findings and gross specimens,the tumor presented as a solitary lesion or a multifocal space-occupying lesion.The tumor size ranged from 5.0 cm × 3.5 cm × 2.0 cm to 13.8 cm × 9.0 cm × 7.7 cm,and the 0.2-1.1 cm nodules were diffusely distributed within the multifocal tumor.Seven cases were surgically resected,three cases underwent biopsy and the two fetuses were aborted.Histologically,nine cases were classified as typeⅠ and three as type Ⅱ,presenting aggressive morphologic features,immature vessels,active mitosis and necrosis.An inflammatory component,predominantly eosinophilic granulocytes,sometimes obscured the nature of the tumor.Ten patients are alive after a follow-up of 1-9 years.Based on immunohistochemistry,the endothelial cells in all cases were positive for CD31,CD34 and polyclonal factor Ⅷ antigen,whereas the scattered hyperplasia bile ducts were positive for cytokeratin 8 and cytokeratin 18.CONCLUSION:The clinical manifestations of IHE are non-specific.There is no significant correlation between histological type and prognosis.The clinicopathologic features of IHE in Chinese patients may provide a clue to further evidence-based studies. | Zhang Zhang,Hui-Jiao Chen,Wen-Juan Yang,Hong Bu,Bing Wei,Xiao-Yu Long,Jing Fu,Rui Zhang,Yun-Bi Ni,Hong-Ying Zhang,Department of Pathology,West China Hospital,Sichuan University,Guoxuexiang 37,Chengdu 610041,Sichuan Province,China | 2010 | World Journal of Gastroenterology2010，16，36： | 16 |
| 2 | Novel adaptive neural control of flexible air-breathing hypersonic vehicles based on sliding mode differentiator显示文摘A novel adaptive neural control strategy is exploited for the longitudinal dynamics of a generic flexible air-breathing hypersonic vehicle(FAHV).By utilizing functional decomposition method, the dynamics of FAHV is decomposed into the velocity subsystem and the altitude subsystem.For each subsystem, only one neural network is employed for the unknown function approximation.To further reduce the computational burden, minimal-learning parameter(MLP)technology is used to estimate the norm of ideal weight vectors rather than their elements.By introducing sliding mode differentiator(SMD) to estimate the newly defined variables, there is no need for the strict-feedback form and virtual controller.Hence the developed control law is considerably simpler than the ones derived from back-stepping scheme.Finally, simulation studies are made to illustrate the effectiveness of the proposed control approach in spite of the flexible effects, system uncertainties and varying disturbances. | Bu Xiangwei Wu Xiaoyan Ma Zhen Zhang Rui | 2015 | Chinese Journal of Aeronautics2015，28，4： | 11 |
| 3 | Observations of atmospheric pollutants at Lhasa during 2014-2015:Pollution status and the influence of meteorological factors显示文摘Atmospheric pollutants including SO_2, NO_2, CO, O_3 and inhalable particulate matter(PM2.5 and PM10) were monitored continuously from March 2014 to February 2015 to investigate characteristics of air pollution at Lhasa, Tibetan Plateau. Species exhibited similar seasonal variations except O_3, with the peaks in winter but low valleys in summer. The maximum O_3 concentration was observed in spring, followed by summer, autumn, and winter. The positive correlation between O_3 and PM10 in spring indicated similar sources of them, and was assumed to be turbulent transport. Temperature was the dominant meteorological factor for most species in spring. High temperature accelerates O_3 photochemistry, and favors air disturbance which is conductive to dust resuspension in spring. Relative humidity(RH) and atmospheric pressure were the main meteorological factors in summer. RH showed negative correlations with species, while atmospheric pressure posed opposite situation. Wind speed(WS) was the dominant meteorological factor in autumn, the negative correlations between WS and species indicated diffusion by wind. Most species showed non-significant correlations with meteorological factors in winter, indicating the dependence of pollution on source emission rather than restriction by meteorology. Pollution weather character indicated that emissions were from biomass burning and dust suspension, and meteorological factors also played an important role. Air stream injection from the stratosphere was observed during O_3 pollution period. Air parcels from Southwest Asia were observed during air pollution period in winter. An enhancement in air pollutants such as O_3 would be expected in the future, more attention should be given to countermeasures for prevention of air pollution in the future. | Bu Duo Lulu Cui Zhenzhen Wang Rui Li Liwu Zhang Hongbo Fu Jianmin Chen Huifang Zhang A.Qiong | 2018 | Journal of Environmental Sciences2018，30，1： | 9 |
| 4 | Treatment results and prognostic factors of patients undergoing postoperative radiotherapy for laryngeal squamous cell carcinoma显示文摘Postoperative radiotherapy (PRT) is widely advocated for patients with squamous cell carcinomas of the head and neck that are considered to be at high risk of recurrence after surgical resection. The aims of this study were to evaluate the treatment outcomes of PRT for patients with laryngeal carcinoma and to identify the value of several prognostic factors. We reviewed the records of 256 patients treated for laryngeal squamous cell carcinoma between January 1993 and December 2005. Disease-free survival (DFS) and overall survival (OS) were estimated using the Kaplan-Meier method. Log-rank test was employed to identify significant prognostic factors for DFS and OS. The Cox proportional hazards model was applied to identify covariates significantly associated with the aforementioned endpoints. Our results showed the 3-, 5-, and 10-year DFS for all patients were 69.9%, 59.5%, and 34.9%, respectively. The 3-, 5-, and 10-year OS rates were 80.8%, 68.6%, and 38.8%, respectively. Significant prognostic factors for both DFS and OS on univariate analysis were grade, primary site, T stage, N stage, overall stage, lymph node metastasis, overall treatment times of radiation, the interval between surgery and radiotherapy, and radiotherapy equipment. Favorable prognostic factors for both DFS and OS on multivariate analysis were lower overall stage, no cervical lymph node metastasis, and using 60Co as radiotherapy equipment. In conclusion, our data suggest that lower overall stage, no cervical lymph node metastasis, and using 60Co as radiotherapy equipment are favorable prognostic factors for DFS and OS and that reducing the overall treatment times of radiation to 6 weeks or less and the interval between surgery and radiotherapy to less than 3 weeks are simple measures to remarkably improve treatment outcome. | Ting Jin Wei-Han Hu Li-Bing Guo Wen-Kuan Chen Qiu-Li Li Hui Lin Xiu-Yu Cai Nan Ge Rui Sun Si-Yi Bu Xin Zhang Meng-Yao Qiu Wei Zhang Su Luo Yi-Xin Zhou | 2011 | Chinese Journal of Cancer2011，30，7： | 5 |
| 5 | DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization. | Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng | 2022 | Building Simulation2022，15，11： | 5 |
| 6 | Reproducibility of the Nottingham modification of the Scarff- Bloom-Richardson histological grading system and the complementary value of Ki-67 to this system显示文摘背景为侵略乳癌(IBC ) 的组织学的分级系统由世界健康组织采用了的 Scarff-Bloom-Richardson (NSBR ) 的诺丁汉修正的重制度() 以前没在中国医院里被学习。增长标记, Ki-67,广泛地在检测 IBC 被使用了。这研究的目的是在中国病理学家和 Ki-67 独立地带给 100 个 IBC 盒子到四个一般病理学家分级的这 system.Methods 的互补价值之中估计 NSBR 系统的重制度,它被专家以前在胸病理分级。在四个一般病理学家之中的 interobserver 重制度和在他们和专家中的每之间的 pairwise 重制度被估计。把索引(Ki-67LI ) 标记的 Ki-67 被 immunohistochemistry 决定,并且它与组织学的等级和幸存的关联是关于 interobserver 重制度的 determined.Results,分级的 NSBR 是相当可再现的(kappa=0.34 ) ;至于分级的 NSBR 的部件,同意为小管形成(kappa=0.46 ) 是最好的,为有丝分裂的计数(kappa=0.28 ) 为原子多形性(kappa=0.42 ) 中间、最差。以 pairwise 重制度,同意对公正与分级的 NSBR (kappa=0.30-0.69 ) 和原子多形性(kappa=0.28-0.69 ) 实质,对中等到为小管形成(kappa=0.51-0.78 ) 实质、细微实质因为有丝分裂的计数(kappa=0.19-0.71 ).There 是为等级的典型 Ki-67LI 范围 1,2 和 3 个肿瘤。Univariate 分析证明 Ki-67 能把等级 2 病人划分成二不同预示的亚群。有否定淋巴节点的等级 2 病人的 Multivariate 分析证明 Ki-67 是为全面 survival.Conclusions 的一个独立预言者由一般病理学家分级的重制度能被提高。在胸病理的专门化为为 IBC 的精确分级和治疗是必要的。与证明预示的意义, Ki-67 把互补价值加到 NSBR 系统。 | ZHANG Rui CHEN Hui-jiao WEI Bing ZHANG Hong-ying PANG Zong-guo ZHU Hong ZHANG Zhang FU Jing BU Hong | 2010 | Chinese Medical Journal2010，，15： | 3 |
| 7 | A new luminescent metal-organic framework for selective sensing of nitroaromatic explosives显示文摘A microporous luminescent metal-organic framework [Zn_4L_2(H_2O)_2].(H_2O)_m(DMA)_n(1)(H_4L=5,5'-((1H-pyrazole-3,5-dicarbonyl)bis(azanediyl))diisophthalic acid, DMA=N,N-dimethylacetamide) was synthesized and characterized by infrared radiation(IR), thermogravimetric analyses(TGA), powder X-ray diffraction spectra(PXRD) and X-ray diffraction. Complex 1has a three dimensional(3D) framework, which can be simplified as 5,5,5,5-c net with the Schlfi symbol of {43.64.83}{44.65.8}{45.65}2. This luminescent metal-organic framework(MOF) shows selectively sensitive to nitrobenzene and series of nitroaromatic explosives such as 4-nitrotoluene, 1,4-dinitrobenzene, 1,3-dinitrobenzene and 2,4-dinitrotoluene, and exhibits well recyclability. So complex 1 could be used to detect nitroaromatic explosives as a selective sensing material. | Tingting Wang Yanyuan Jia Qiang Chen Rui Feng Shouyi Tian Tong-Liang Hu Xian-He Bu | 2016 | Science China Chemistry2016，59，8： | 3 |
| 8 | Factors associated with overall survival in early gastric cancer patients who underwent additional surgery after endoscopic submucosal dissection显示文摘BACKGROUND Controversy exists about the benefit of additional surgery after endoscopic submucosal dissection(ESD)for early gastric cancer(EGC).AIM To examine risk factors for overall survival(OS)after additional surgery in patients with EGC who initially underwent ESD.METHODS This was a retrospective analysis of patients with EGC who underwent additional surgery after ESD at the Beijing Friendship Hospital affiliated to Capital Medical University between August 2012 and August 2019.OS was the primary outcome.Lymph node metastasis and residual tumor were secondary outcomes.Logistic regression models and Kaplan-Meier curves were used for further analysis.RESULTS Forty-two patients were evaluated,including 35(83.3%)males and 7(16.7%)females.The mean age was 62(range,32-82)years.Male sex[hazard ratio(HR)=21.906,95%confidence interval(CI):3.762-229.250;P=0.039),T1b invasion(HR=3.965,95%CI:1.109-17.432;P=0.047),undifferentiated tumor(HR=9.455,95%CI:0.946-29.482;P=0.049),lymph node metastasis(HR=2.126,95%CI:0.002-13.266;P=0.031),and residual tumor(HR=4.275,95%CI:1.049-27.420;P=0.043)were independently associated with OS.The follow-up duration was 4-81 mo(median:50.7 mo).OS was 77.0±12.1 mo(95%CI:53.3-100.7 mo).The 3-year and 5-year OS rates were 94.1%and 85%,respectively.CONCLUSION Male sex,T1b invasion,undifferentiated tumor,lymph node metastasis,and residual tumor are independently associated with OS in patients with EGC who underwent additional surgery after ESD. | Zhi Zheng Fan-Di Bu Hao Chen Jie Yin Rui Xu Jun Cai Jun Zhang Hong-Wei Yao Zhong-Tao Zhang | 2021 | World Journal of Clinical Cases2021，9，10： | 2 |
| 9 | The transcription factors TLR1 and TLR2 negatively regulate trichome density and artemisinin levels in Artemisia annua显示文摘The important antimalarial drug artemisinin is biosynthesized and stored in Artemisia annua glandular trichomes and the artemisinin content correlates with trichome density;however,the factors affecting trichome development are largely unknown.Here,we demonstrate that the A.annua R2R3 MYB transcription factor TrichomeLess Regulator 1(TLR1)negatively regulates trichome development.In A.annua,TLR1 overexpression lines had 44.7%–64.0%lower trichome density and 11.5%–49.4%lower artemisinin contents and TLR1-RNAi lines had 33%–93.3%higher trichome density and 32.2%–84.0%higher artemisinin contents compared with non-transgenic controls.TLR1 also negatively regulates the expression of anthocyanin biosynthetic pathway genes in A.annua.When heterologously expressed in Arabidopsis thaliana,TLR1 interacts with GLABROUS3a,positive regulator of trichome development,and represses trichome development.Yeast two-hybrid and pull-down assays indicated that TLR1 interacts with the WUSCHEL homeobox(WOX)protein AaWOX1,which interacts with the LEAFY-like transcription factor TLR2.TLR2 overexpression in Arabidopsis and A.annua showed that TLR2 reduces trichome development by reducing gibberellin levels.Furthermore,artemisinin contents were 19%–43%lower in TLR2-overexpressing A.annua plants compared to controls.These data indicate that TLR1 and TLR2 negatively regulate trichome density by lowering gibberellin levels and may enable approaches to enhance artemisinin yields. | Zongyou Lv JinXing Li Shi Qiu Fei Qi Hang Su Qitao Bu Rui Jiang Kexuan Tang Lei Zhang Wansheng Chen | 2022 | Journal of Integrative Plant Biology2022，64，6： | 2 |
| 10 | The Oxidation of Cyclohexene with Polymer Supported Co(II) in Supercritical Carbon Dioxide显示文摘The cyclohexene 1 was oxidized with polymer-supported 2.2-bipyridine cobalt(II) complex in the presence of CO2. The conversion and selectivity was sensitive to the pressure of CO2. | Jun LIU, Rui ZHANG, Liang GAO, Tao JIANG, Zhi Min LIU, Jun HE, Bu Xing HAN*, Guan Ying YANG Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080 | 2002 | Chinese Chemical Letters2002，13，12： | 1 |
| 11 | Cavity optimization for investment casting die of turbine blade based on reverse engineering显示文摘 | Ding Hua Zhang Rui Song Jiang Jian Ling Li Wen Hu Wang Kun Bu | 2010 | The International Journal of Advanced Manufacturing Technology2010，，9： | 1 |
| 12 | Methanothermal reduction of mixtures of PbSO 4 and PbO 2 to synthesize ultrafine α-PbO powders for lead acid batteries显示文摘 | Pengran Gao Yi Liu Weixin Lv Rui Zhang Wei Liu Xianfu Bu Guanghua Li Lixu Lei | 2014 | Journal of Power Sources2014，，： | 1 |
| 13 | In-situ cation exchange enhances room temperature phosphorescence of a family of metal-organic frameworks显示文摘The rational designability and chemical tunability of metal-organic frameworks(MOFs)are enabling tributes to efficaciously enhance their room temperature phosphorescence(RTP)performance.A family of stable anionic MOFs,[Zn_(2)(4,5-ImDC)_(2)]M_(2)(NKU-132,M=(CH_(3))_(2)NH_(2)or(CH_(2)CH_(3))_(2)NH_(2)),featuring significant RTP have been synthesized.By rational cation selection and in-situ replacement from dimethylammonium to diethylammonium,the phosphorescence lifetime is increased from 30.88 to126.3 ms,along with less sensitivity to air.This work provides an anti-quenching and lifetime tuning example for RTP-MOFmaterials via facile host-guest chemistry. | Rui Feng Zi-Ying Li Zhao-Quan Yao Zi-Ang Guo Yi-Nan Zhang Hao-Xiang Sun Wei Li Xian-He Bu | 2022 | Science China Chemistry2022，65，1： | 1 |
| 14 | Weighted estimates for bilinear square functions with non-smooth kernels and commutators显示文摘Under weaker conditions on the kernel functions,we discuss the boundedness of bilinear square functions associated with non-smooth kernels on the product of weighted Lebesgue spaces.Moreover,we investigate the weighted boundedness of the commutators of bilinear square functions(with symbols which are BMO functions and their weighted version,respectively)on the product of Lebesgue spaces.As an application,we deduce the corresponding boundedness of bilinear Marcinkiewicz integrals and bilinear Littlewood-Paley^-functions. | Rui BU Zunwei FU Yandan ZHANG | 2020 | Frontiers of Mathematics in China2020，15，1： | 1 |
| 15 | Compactness for the commutators of multilinear singular integral operators with non-smooth kernels显示文摘In this paper, the behavior for commutators of a class of bilinear singular integral operators associated with non-smooth kernels on the product of weighted Lebesgue spaces is considered. By some new maximal functions to control the commutators of bilinear singular integral operators and CMO(Rn) functions, compactness for the commutators is proved. | BU Rui CHEN Jie-cheng | 2019 | Applied Mathematics(A Journal of Chinese Universities)2019，34，1： | 1 |
| 16 | Nonsingular di- rect neural control of air - breathing hypersonic vehicle via back - stepping显示文摘 | Bu Xiangwei Wu Xiaoyan Ma Zhen Zhang Rui | 2015 | Neurocomputing2015，153，： | 1 |
| 17 | A highly stable terbium metal-organic framework for efficient detection of picric acid in water显示文摘A highly stable fluorescent terbium MOF(Tb_(4)(paip)_(6)·1.2 H_(2) O,paip = 5-(1 H-pyrazole-4-yl)isophthalate)showing a sharp green emission(545 nm) and a quantum yield of 21.0% was successfully synthesized.This compound is shown to be a recyclable sensor for detecting picric acid in aqueous solution with both high sensitivity and selectivity,attributed to the electron transfer quenching mechanism. | Zi-Ying Li Zhao-Quan Yao Rui Feng Ming-Hua Sun Xiao-Tian Shan Zi-Hao Su Wei Li Xian-He Bu | 2021 | Chinese Chemical Letters2021，32，10： | 1 |
| 18 | Measuring Viscoelastic Properties of Living Cells显示文摘Precise measurement of mechanical properties of living cells is important in understanding their mechanics-biology relations.In this study,we adopted the atomic force microscope to measure the creep deformation and stress relaxation of six different human cell lines.We examined whether the measured creep and relaxation trajectories satisfy a verification relation derived based on the linear viscoelastic theory.We compared the traditional spring-dashpot and the newly developed power-law-type constitutive relations in fitting the experimental measurements.We found that the human normal liver(L02),hepatic cancer(HepG2),hepatic stellate(LX2)and gastric cancer(NCI-N87)cell lines are linear viscoelastic materials,and human normal gastric(GES-1)and gastric cancer(SGC7901)cell lines are nonlinear due to failing in satisfying the verification relation for linear viscoelastic theory.The three-parameter power-law-type const计utive relation can fit the experimentai measurements better than that of the five-parameter classical spring-dashpot. | Yang Bu Long Li Chendong Yang Rui Li Jizeng Wang | 2019 | Acta Mechanica Solida Sinica2019，32，5： | 0 |
| 19 | An Important Minor Figure Hugh Whitbread in Virginia Woolf's Mrs. Dalloway显示文摘 | BU Yu-wei LI Rui | 2012 | US-China Foreign Language2012，10，8： | 0 |
| 20 | Boundedness of iterated spherical average显示文摘The iterated spherical average∆(A1)^(N)is an important operator in harmonic analysis,and has very important applications in approximation theory and probability theory,where∆is the Laplacian,A_(1)is the unit spherical average and(A1)^(N)is its iteration.In this paper,we mainly study the sufficient and necessary conditions for the boundedness of this operator in Besov-Lipschitz space,and prove the boundedness of the operator in Triebel-Lizorkin space.Moreover,we use above conclusions to improve the existing results of the boundedness of this operator in L^(p)space. | Rui BU Qiang HUANG Yingjun SHAO | 2023 | Frontiers of Mathematics in China2023，18，2： | 0 |
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