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| 1 | SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts显示文摘The ongoing outbreak of Coronavirus Disease 2019(COVID-19)has become a global public health emergency.SARScoronavirus-2(SARS-CoV-2),the causative pathogen of COVID-19,is a positive-sense single-stranded RNA virus belonging to the family Coronaviridae.For RNA viruses,virus-encoded RNA helicases have long been recognized to play pivotal roles during viral life cycles by facilitating the correct folding and replication of viral RNAs.Here,our studies show that SARS-CoV-2-encoded nonstructural protein 13(nsp13)possesses the nucleoside triphosphate hydrolase(NTPase)and RNA helicase activities that can hydrolyze all types of NTPs and unwind RNA helices dependently of the presence of NTP,and further characterize the biochemical characteristics of these two enzymatic activities associated with SARS-CoV-2 nsp13.Moreover,we found that some bismuth salts could effectively inhibit both the NTPase and RNA helicase activities of SARS-CoV-2 nsp13 in a dose-dependent manner.Thus,our findings demonstrate the NTPase and helicase activities of SARS-CoV-2 nsp13,which may play an important role in SARS-CoV-2 replication and serve as a target for antivirals. | Ting Shu Muhan Huang Di Wu Yujie Ren Xueyi Zhang Yang Han Jingfang Mu Ruibing Wang Yang Qiu Ding-Yu Zhang Xi Zhou | 2020 | Virologica Sinica2020，35，3： | 11 |
| 2 | Biosynthesis and regulation of diterpenoids in medicinal plants显示文摘Plant diterpenoids are widely distributed and abundant natural products with diverse structures and functions in nature,which have been commonly used in pharmaceutical,agricultural and industrial production.In recent years,plant diterpenoids have attracted increasing attention,including their biosynthetic pathways,transcriptional regulatory networks,and biological functions.Herein,the biosynthetic pathways of diterpenoids are summarized in a modular fashion.Further,the regulatory network between diterpene biosynthesis and environmental factors is reviewed.Insights into diterpene metabolism may drive elucidation of complex active diterpene pathways and serve as a knowledge repository for metabolic engineering and cell factory construction. | REN Junze WU Yu HU Zhanpin CHEN Ruibing ZHANG Lei | 2022 | Chinese Journal of Natural Medicines2022，20，10： | 3 |
| 3 | Determination of phenylurea and triazine herbicides in milk by microwave assisted ionic liquid microextraction high-performance liquid chromatography显示文摘 | Shiqian Gao Jingyan You Xia Zheng Ying Wang Ruibing Ren Rui Zhang Yuping Bai Hanqi Zhang | 2010 | Talanta2010，，4： | 1 |
| 4 | Determination of the active constituents in Arnebia euchroma (Royle) Johnst. by ionic liquid-based ultrasonic-assisted extraction high-performance liquid chromatography显示文摘 | Yao Xiao Ying Wang Shiqian Gao Rui Zhang Ruibing Ren Na Li Hanqi Zhang | 2011 | Journal of Chromatography B2011，，20： | 1 |
| 5 | On the Development and Maintenance of Cigarettes Exported to North Korea显示文摘According to the requirements of ' going out' strategy of Jilin Tobacco Industry Co. Ltd.,in order to further expand the Changbaishan series brand in the market of North Korea,this paper elaborates the product development and maintenance ideas and measures for three cigarette companies in North Korea based on the actual work being done,so as to determine the development and maintenance focus of export cigarettes and provide strong technical support for accelerating the pace of localization of production while achieving homogenization of production. | Hongwei PIAO Yonghua JIN Mingxie SONG Ming CHEN Ruibing REN Wenlong ZHANG | 2015 | Asian Agricultural Research2015，7，1： | 0 |
| 6 | Non-Covalent Functionalization of Graphene with Bisphenol A for High-Performance Supercapacitors显示文摘The reduced graphene oxide(RGO)/bisphenol A(BPA)composites were prepared by an adsorption-reduction method.The composites are characterized by X-ray diffraction(XRD),UV-vis,thermogravimetric(TG)analysis,field emission scanning electron microscopy(FESEM),transmission electron microscopy(TEM).The results confirm that BPA is adsorbed on the basal plane of RGO byπ-πstacking interaction.Furthermore,the electrochemical behaviors were evaluated by cyclic voltammetry,galvanostatic charge/discharge techniques and electrochemical impedance spectroscopy(EIS).The results show that the RGO/BPA nanocomposites exhibit ultrahigh specific capacitance of 466 F•g^(−1) at a current density of 1 A•g^(−1),excellent rate capability(more than 81%retention at 10 A•g^(−1) relative to 1 A•g^(−1))and superior cycling stability(90%capacitance decay after 4000 cycles).Consequently,the RGO/BPA nanocomposites can be regarded as promising electrode materials for supercapacitor applications. | Haixiong Hu Zhongai Hu Xiaoying Ren Yuying Yang Ruibing Qiang Ning An Hongying Wu | 2015 | Chinese Journal of Chemistry2015，33，2： | 0 |
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