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| 1 | Effects of soil properties on production and bioaccumulation of methylmercury in rice paddies at a mercury mining area,China显示文摘Rice paddy soil is recognized as the hotspot of mercury(Hg) methylation, which is mainly a biotic process mediated by many abiotic factors. In this study, effects of key soil properties on the production and bioaccumulation of Hg and methylmercury(MeHg) in Hg-contaminated rice paddies were investigated. Rice and soil samples were collected from the active Hg smelting site and abandoned Hg mining sites(a total of 124 paddy fields) in the Wanshan Mercury Mine, China. Total Hg(THg) and MeHg in soils and rice grains, together with sulfur(S),selenium(Se), organic matter(OM), nitrogen(N), phosphorus(P), mineral compositions(e.g., SiO_2, Al_2O_3 and Fe_2O_3) and pH in soils were quantified. The results showed that long-term Hg mining activities had resulted in THg and MeHg contaminations in soil-rice system. The newly-deposited atmospheric Hg was more readily methylated relative to the native Hg already in soils, which could be responsible for the elevated MeHg levels in soils and rice grains around the active artificial Hg smelting site. The MeHg concentrations in soils and rice grains showed a significantly negative relationship with soil N/Hg, S/Hg and OM/Hg ratio possibly due to the formation of low-bioavailability Hg–S(N)–OM complexes in rhizosphere. The Hg–Se antagonism undoubtedly occurred in soil-rice system, while its role in bioaccumulation of MeHg in the MeHg-contaminated rice paddies was minor. However, other soil properties showed less influence on the production and bioaccumulation of MeHg in rice paddies located at the Wanshan Mercury Mine zone. | Deliang Yin Tianrong He Runsheng Yin Lingxia Zeng | 2018 | Journal of Environmental Sciences2018，30，6： | 8 |
| 2 | Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens显示文摘Naturally,resistant crop germplasms are important resources for managing the issues of agricultural product safety and environment deterioration.We found a spontaneous mutant of‘Newhall’navel orange(Citrus sinensis Osbeck)(MT)with broad-spectrum protections against fungal pathogens in the orchard,postharvest-storage,and artificial inoculation conditions.To understand the defense mechanism of MT fruit,we constructed a genome-scale metabolic network that integrated metabolome and transcriptome datasets.The coordinated transcriptomic and metabolic data were enriched in two sub-networks,showing the decrease in very long chain fatty acid(by 41.53%)and cuticular wax synthesis(by 81.34%),and increase in the synthesis of jasmonic acid(JA)(by 95.23%)and JA-induced metabolites such as 5-dimethylnobietin(by 28.37%)in MT.Furthermore,cytological and biochemical analyses confirmed that the response to fungal infection in MT was independent of wax deficiency and was correlated with the levels of jasmonates,and the expression of plant defensin gene PDF1.2.Results of exogenous application of MeJA and JA inhibitors such as propyl gallate proved that JA-mediated defense contributes to the strong tolerance against pathogens in MT.Our results indicated that jasmonate biosynthesis and signaling are stimulated by the fatty acid redirection of MT,and participate in the tolerance of pathogenic fungi. | Yizhong He Jingwen Han Runsheng Liu Yuduan Ding Jinqiu Wang Li Sun Xiaoming Yang Yunliu Zeng Weiwei Wen Juan Xu Hongming Zhang Xiang Yan Zhaoxing Chen Zuliang Gu Hong Chen Huanqing Tang Xiuxin Deng Yunjiang Cheng | 2018 | Horticulture Research2018，5，1： | 8 |
| 3 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 4 | AlphaFold2 and its applications in the fields of biology and medicine显示文摘AlphaFold2(AF2)is an artificial intelligence(AI)system developed by DeepMind that can predict three-dimensional(3D)structures of proteins from amino acid sequences with atomic-level accuracy.Protein structure prediction is one of the most challenging problems in computational biology and chemistry,and has puzzled scientists for 50 years.The advent of AF2 presents an unprecedented progress in protein structure prediction and has attracted much attention.Subsequent release of structures of more than 200 million proteins predicted by AF2 further aroused great enthusiasm in the science community,especially in the fields of biology and medicine.AF2 is thought to have a significant impact on structural biology and research areas that need protein structure information,such as drug discovery,protein design,prediction of protein function,et al.Though the time is not long since AF2 was developed,there are already quite a few application studies of AF2 in the fields of biology and medicine,with many of them having preliminarily proved the potential of AF2.To better understand AF2 and promote its applications,we will in this article summarize the principle and system architecture of AF2 as well as the recipe of its success,and particularly focus on reviewing its applications in the fields of biology and medicine.Limitations of current AF2 prediction will also be discussed. | Zhenyu Yang Xiaoxi Zeng Yi Zhao Runsheng Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 1 |
| 5 | Copper(Ⅱ)-catalyzed synthesis of N-substituted-3-amino-4-cyanoisoquinoline-1(2H)-ones by the reaction of N-substituted-2-iodobenzamides with malononitrile显示文摘 | LIU Yeye ZENG Runsheng PAN Jie | 2014 | Chin J Chem2014，32，9： | 1 |
| 6 | Copper(I)-Catalyzed 3-Position Methylation of Coumarins by Using Di-tert-butyl Peroxide as the Methylation Reagents显示文摘由使用 di-tert-butyl 过氧化物(DTBP ) 的香豆素的催化铜的 methylation 被描述了。反应提供直接存取给大量 3-methylcoumarins 在对好收益中等。在这个过程, DTBP 不仅作为氧化剂,而且作为甲基来源被采用,是引人注目的。 | Huan Zhuang Runsheng Zeng Jianping Zou | 2016 | Chinese Journal of Chemistry2016，34，4： | 1 |
| 7 | One-pot Copper Nanoparticle-catalyzed Synthesis of Imidazo[1,2-α]pyridines Under Solvent-free Conditions显示文摘 | ZONG Chenglong ZENG Runsheng ZOU Jianping | 2014 | Chemical Research in Chinese Universities2014，30，4： | 1 |
| 8 | Efficient C-S Cross-Coupling of Thiols with Aryl Iodides Catalyzed by Cu(OAc)_(2)·H_(2)O and 2,2'-Biimidazole显示文摘The classical Ullmann C-S cross coupling reaction of aryl iodides with aromatic/alkyl thiols under catalysis of 15 mol%Cu(OAc)_(2)·H_(2)O and 15 mol%2,2'-biimidazole works at 80℃in DMSO for 3 h to provide a variety of aryl sulfides in good to excellent yields. | Chenglong Zong Jianli Liu Shengyan Chen Runsheng Zeng Jianping Zou | 2014 | Chinese Journal of Chemistry2014，32，3： | 0 |
| 9 | Copper(Ⅱ)-Catalyzed Synthesis of N-Substituted-3-amino-4- cyano-isoquinoline-1(2H)-ones by the Reaction of N-Substituted-2-iodobenzamides with Malononitrile显示文摘A novel Cu(OAc)_(2)•H_(2)O catalyzed coupling reaction of N-substituted-2-iodobenzamides with malononitrile to afford N-substituted-3-amino-4-cyano-isoquinoline-1(2H)-ones is described.The reaction proceeded in DMSO at 90℃ for 5 h in nitrogen without external ligands. | Yeye Liu Runsheng Zeng Jie Pan Jianping Zou | 2014 | Chinese Journal of Chemistry2014，32，9： | 0 |
| 10 | Cul-Catalyzed Multicomponent Synthesis of Aminoindolizines from Aldehydes, Amines, and Alkynes under Solvent-Free Conditions显示文摘通过 CuI 在没有溶剂的条件下面催化的 heteroaryl 醛,第二等的胺和终端炔属羟的三部件的一个壶反应的 1-aminoindolizines 的一条直接、有效的途径被开发了。这方法论向快速的存取提供到代替的 aminoindolizines 好收益(多达 97%) 。 | Changming Pan Jianping Zou Runsheng Zeng | 2013 | Chinese Journal of Chemistry2013，31，6： | 0 |
| 11 | Studies on the Structure-Activity Relationship of p-Substituted Thiobenzanilides as Extractant for Pd( Ⅱ )显示文摘Introduction The metal extraction is a process of complex formation by organic ligands with metal ions or corresponding ionic groups, that is to say, it is a multicomponent coordination process in the heterogeneous phase system. The property of extraction is chiefly dependent on the stability of metal complexes, which is closely related to both the structure of ligands and the nature of metal ions. Therefore, the physicochemical behaviour of the substituent in the ligand will influence the extractive ability of the extractant for a | Lu Zhong’ e, Zeng Runsheng and Sun Daqing (Department of Chemistry, Suzhou University, Suzhou) | 1991 | Chemical Research in Chinese Universities1991，7，3： | 0 |
| 12 | Copper(Ⅱ) and 1,1 '-Trimethylene-2,2'-biimidazole-promoted Arylation of Acetylacetone with Aryl Iodides显示文摘一个新、有效的方法被开发在 100 点在 Cu (II ) 和 1,1-trimethylene-2,2-biimidazole 的帮助下面与芳基碘化物执行 acetylacetone | Liu Jianli Zeng Runsheng Zhou Chunmei Zou Jianping | 2011 | Chinese Journal of Chemistry2011，29，2： | 0 |
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