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| 1 | Amazing structure of respirasome: unveiling the secrets of cell respiration显示文摘Respirasome,执行细胞的呼吸的一台巨大的分子的机器,自从它的发现,获得了成长注意,因为呼吸是在几乎所有生活动物的最不可缺少的生物过程。respirasome 的概念更新了我们呼吸的链组织的理解,并且最最近, respirasome 的结构从清华大学由 Yangs 组解决了(Gu 等。自然 237 (7622 ): 639-643, 2016 ) 第一在这台巨大的分子的机器以内介绍了详细相互作用,并且为药设计提供了重要信息并且屏蔽。然而,细胞的呼吸的学习通过了长历史。这里,我们简短显示出呼吸的链调查的 detoured 历史,然后描述了 respirasome 的令人惊讶的结构。 | Runyu Guo Jinke Gu Meng Wu Maojun Yang | 2016 | Protein & Cell2016，7，12： | 7 |
| 2 | Characteristics of organic phosphorus fractions in different trophic sediments of lakes from the middle and lower reaches of Yangtze River region and Southwestern Plateau, China显示文摘 | Runyu Zhang Fengchang Wu Congqiang Liu Pingqing Fu Wen Li Liying Wang Haiqing Liao Jianyang Guo | 2007 | Environmental Pollution2007，，2： | 5 |
| 3 | Structure of the intact 14-subunit human cytochrome c oxidase显示文摘 | Shuai Zong Meng Wu Jinke Gu Tianya Liu Runyu Guo Maojun Yang | 2018 | Cell Research2018，28，10： | 5 |
| 4 | Goose Toll-like receptor 7 (TLR7), myeloid differentiation factor 88 (MyD88) and antiviral molecules involved in anti-H5N1 highly pathogenic avian influenza virus response显示文摘 | Liangmeng Wei Peirong Jiao Runyu Yuan Yafen Song Pengfei Cui Xuchen Guo Bofang Zheng Weixin Jia Wenbao Qi Tao Ren Ming Liao | 2013 | 2013 (1-2)2013，，1： | 1 |
| 5 | Goose Toll-like receptor 7 (TLR7), myeloid differentiation factor 88 (MyD88) and antiviral molecules involved in anti-H5N1 highly pathogenic avian influenza virus response显示文摘 | Liangmeng Wei Peirong Jiao Runyu Yuan Yafen Song Pengfei Cui Xuchen Guo Bofang Zheng Weixin Jia Wenbao Qi Tao Ren Ming Liao | 2013 | Veterinary Immunology and Immunopathology (-)2013，，1： | 1 |
| 6 | Characteristics of organic phosphorus fractions in different trophic sediments of lakes from the middle and lower reaches of Yangtze River region and Southwestern Plateau, China显示文摘 | Runyu Zhang Fengchang Wu Congqiang Liu Pingqing Fu Wen Li Liying Wang Haiqing Liao Jianyang Guo | 2007 | Environmental Pollution2007，，2： | 1 |
| 7 | Research journey of respirasome显示文摘Respirasome,as a vital part of the oxidative phosphorylation system,undertakes the task of transferring electrons from the electron donors to oxygen and produces a proton concentration gradient across the inner mitochondrial membrane through the coupled translocation of protons.Copious research has been carried out on this lynchpin of respiration.From the discovery of individual respiratory complexes to the report of the high-resolution structure of mammalian respiratory supercomplex I1III2IV1,scientists have gradually uncovered the mysterious veil of the electron transport chain(ETC).With the discovery of the mammalian respiratory mega complex I2III2IV2,a new perspective emerges in the research field of the ETC.Behind these advances glitters the light of the revolution in both theory and technology.Here,we give a short review about how scientists‘see’the structure and the mechanism of respirasome from the macroscopic scale to the atomic scale during the past decades. | Meng Wu Jinke Gu Shuai Zong Runyu Guo Tianya Liu Maojun Yang | 2020 | Protein & Cell2020，11，5： | 1 |
| 8 | UQCRFSIN assembles mitochondrial respiratory complex-Ill into an asymmetric 21-subunit dimer显示文摘 | Shuai Zong Jinke Gu Tianya Liu Runyu Guo Meng Wu Maojun Yang | 2018 | Protein & Cell2018，9，6： | 1 |
| 9 | Optically-generated focused ultrasound for noninvasive brain stimulation with ultrahigh precision显示文摘High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological diseases.Current non-invasive neuromodulation methods offer limited precision at the milimeter level.Here,we report opticallygenerated focused ultrasound(OFUS)for non-invasive brain stimulation with ultrahigh precision.OFUS is generated by a soft optoacoustic pad(SOAP)fabricated through embedding candle soot nanoparticles in a curved polydimethylsiloxane film.SOAP generates a transcranial ultrasound focus at 15 MHz with an ultrahigh lateral resolution of 83μm,which is two orders of magnitude smaller than that of conventional transcranial-focused ultrasound(tFUS).Here,we show effective OFUS neurostimulation in vitro with a single ultrasound cycle.We demonstrate submillimeter transcranial stimulation of the mouse motor cortex in vivo.An acoustic energy of 0.6 mJ/cm?,four orders of magnitude less than that of tFUS,is suffcient for successful OFUS neurostimulation.OFUS offers new capabilities for neuroscience studies and disease treatments by delivering a focus with ultrahigh precision noninvasively. | Yueming Li Ying Jiang Lu Lan Xiaowei Ge Ran Cheng Yuewei Zhan Guo Chen Linli Shi Runyu Wang Nan Zheng Chen Yang Ji-Xin Cheng | 2022 | Light(Science & Applications)2022，11，11： | 1 |
| 10 | SNP-based identification of QTL for resistance to black point caused by Bipolaris sorokiniana in bread wheat显示文摘Black point disease caused by Bipolaris sorokiniana is a problem in wheat production worldwide.We aimed to identify major quantitative trait loci(QTL)for resistance to black point and develop molecular markers for marker-assisted selection(MAS).A recombinant inbred line(RIL)population derived from a cross between Wanyuanbai 1(susceptible)and SN4143(resistant)was evaluated for black point response at three locations during two years under artificial inoculation with B.sorokiniana,providing data for six environments.Thirty resistant and 30 susceptible RILs were selected to form resistant and susceptible bulks,respectively,that were genotyped by the wheat 660 K SNP array;685 singlenucleotide polymorphisms(SNPs)were identified,among which 385(56.2%)and 115(16.8%)were located on chromosomes 4 A and 2 B,respectively.Bulked segregant RNA-Seq analysis identified candidate regions on chromosomes 4 A(4.60–40.28 Mb)and 5 A(1.22–48.47 Mb).Genetic linkage maps were constructed for chromosomes 2 B,4 A,and 5 A using 59 polymorphic d CAPS and SSR markers.Finally,two QTL,designated QBB.hau-4 A and QBB.hau-5 A,were detected on chromosomes 4 A and 5 A,respectively.The resistance allele of QBB.hau-4 A was derived from SN4143,and that of QBB.hau-5 A came from Wanyuanbai 1.QBB.hau-4 A with a large and consistent effect(15.1%)is likely to be a new locus for black point resistance.The markers linked to QBB.hau-4 A and QBB.hau-5 A have potential application in MASbased breeding. | Qiaoyun Li Runyu Hu Zhenfeng Guo Siyu Wang Chuang Gao Yumei Jiang Jianwei Tang Guihong Yin | 2022 | The Crop Journal2022，10，3： | 1 |
| 11 | 哺乳动物呼吸链超级复合物的Ⅰ1Ⅲ2Ⅳ1结构显示文摘在哺乳动物线粒体内膜上,呼吸链复合物进一步聚合成超级复合物来进行电子传递,并转运质子形成电化学梯度用以合成ATP。此前,呼吸链超级复合物的精细结构信息并不清楚。 | Meng Wu Jinke Gu Runyu Guo Yushen Huang 杨茂君 | 2017 | 科学新闻2017，19，4： | 0 |
| 12 | Structure of intact human MCU supercomplex with the auxiliary MICU subunits显示文摘Dear Editor,Mitochondrial Ca2+homeostasis regulates energy production,cell division,and cell death.The basic properties of mitochondrial Ca2+uptake have been firmly established.The Ca2+influx is mediated by MCU,driven by membrane potential and using a uniporter mechanism(Vasington and Murphy,1962).Patch-clamp analysis of MCU currents demonstrated that MCU is a channel with exceptionally high Ca2+selectivity(Kirichok et al.,2004). | Wei Zhuo Heng Zhou Runyu Guo Jingbo Yi Laixing Zhang Lei Yu Yinqiang Sui Wenwen Zeng Peiyi Wang Maojun Yang | 2021 | Protein & Cell2021，12，3： | 0 |
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