6篇
您的检索式：作者名="SANJIV SAM GAMBHIR"
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| 1 | Tumor Molecular Imaging with Nanoparticles显示文摘Molecular imaging(MI)can provide not only structural images using traditional imaging techniques but also functional and molecular information using many newly emerging imaging techniques.Over the past decade,the utilization of nanotechnology in MI has exhibited many significant advantages and provided new opportunities for the imaging of living subjects.It is expected that multimodality nanoparticles(NPs)can lead to precise assessment of tumor biology and the tumor microenvironment.This review addresses topics related to engineered NPs and summarizes the recent applications of these nanoconstructs in cancer optical imaging,ultrasound,photoacoustic imaging,magnetic resonance imaging(MRI),and radionuclide imaging.Key challenges involved in the translation of NPs to the clinic are discussed. | Zhen Cheng Xuefeng Ya Xilin Sun BaozhongShen Sanjiv Sam Gambhir | 2016 | Engineering2016，2，1： | 2 |
| 2 | 18F-FDG PET/CT evaluation of patients with ovarian carcinoma显示文摘 | Andrei H. Iagaru Erik S. Mittra Iain Ross McDougall Andrew Quon Sanjiv Sam Gambhir | 2008 | Nuclear Medicine Communications2008，，： | 1 |
| 3 | A Comparison Between Time Domain and Spectral Imaging Systems for Imaging Quantum Dots in Small Living Animals显示文摘 | Adam de la Zerda Sunil Bodapati Robert Teed Meike L. Schipper Shay Keren Bryan R. Smith Johnny S. T. Ng Sanjiv Sam Gambhir | 2010 | Molecular Imaging and Biology2010，，5： | 1 |
| 4 | Novel Strategy for a Cocktail ^sup 18^F-Fluoride and ^sup 18^F-FDG PET/CT Scan for Evaluation of Malignancy: Results of the Pilot-Phase Study显示文摘 | Iagaru Andrei Mittra Erik Yaghoubi Shahriar S Dick David W Quon Andrew Goris Michael L Gambhir Sanjiv Sam | 2009 | The Journal of Nuclear Medicine2009，，： | 1 |
| 5 | A NEAR-INFRARED FLUORESCENT DEOXYGLUCOSE DERIVATIVE FOR OPTICAL IMAGING OF EXPERIMENTAL ARTHRITIS显示文摘The purpose of this study is to investigate whether a near-infrared fluorescence(NIRF)probe,Cy5.5-d-glucosamine(Cy5.5-2DG),can image arthritis in collagen-induced arthritic(CIA)mice.The presence of arthritis was verified by both visual examination and micro-computed tomography(MicroCT)imaging.CIA mice were imaged by a micro-positron emission tomography(MicroPET)scanner one hour after intravenous injection of 2-deoxy-2-[18F]fluoro-d-glucose([18F]FDG).After radioactivity of[18F]FDG decayed away,Cy5.5-2DG was injected into a lateral tail vein of the mice.Arthritic tissue targeting and retention of Cy5.5-2DG in CIA mice were evaluated and quantified by an optical imaging system.Inflammatory tissue in CIA mice was clearly visualized by[18F]FDG-MicroPET scan.NIRF imaging of Cy5.5-2DG in the same mice revealed that the pattern of localization of Cy5.5-2DG in the arthritic tissue was very similar to that of[18F]FDG.Quantification analysis further showed that[18F]FDG uptake in arthritic tissues at one hour post-injection(p.i.)and Cy5.5-2DG uptakes at different time points p.i.were all well correlated(r2 over 0.65).In conclusion,Cy5.5-DG can detect arthritic tissues in living mice.The good correlation between the[18F]FDG uptake and Cy5.5-2DG accumulation in the same arthritic tissue warrants further investigation of Cy5.5-2DG as an approach for assessment of anti-inflammatory treatments. | XIUPING LIU ZHENGMING XIONG SHEEN-WOO LEE JELENA LEVI SHAHRIAR YAGHOUBI SANDIP BISWAL SANJIV SAM GAMBHIR ZHEN CHENG | 2009 | Journal of Innovative Optical Health Sciences2009，2，2： | 0 |
| 6 | 利用纳米粒子进行肿瘤分子成像显示文摘分子成像不仅可以利用传统成像技术提供结构图像,也可利用许多新的成像技术提供生物功能信息和分子信息。在过去的几十年间,纳米技术在分子成像中的应用显示了许多明显的优势,并且为活体成像提供了新的机遇。多模态纳米粒子可对肿瘤的生物性和微环境做出精确评估。本文讨论了与工程化纳米粒子相关的话题,并总结了近几年来这些纳米结构在恶性肿瘤光学成像、超声成像、光声成像、磁共振成像和放射性核素显像中的应用;同时,还讨论了将纳米粒子应用到临床医学中面临的主要挑战。 | 程震 闫雪峰 孙夕林 申宝忠 Sanjiv Sam Gambhir | 2016 | Engineering2016，2，1： | 0 |
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