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| 1 | Serum beta 2-microglobulin as a biomarker in inflammatory bowel disease显示文摘AIM: To investigate the diagnostic utility of beta 2 microglobulin(B2-M) levels and analyze this correlation with the activity of inflammatory bowel disease(IBD).METHODS: Overall, 78 IBD patients and 30 healthy controls were enrolled in the study. We examined B2-M serum levels in 43 ulcerative colitis(UC) patients, 35 with Crohn's disease(CD) and 30 control subjects, using an enzymatic method. Patients were divided into two groups according to two disease types: active and in remission. Subjects were also divided into two subgroups according to extent of the disease: left-side and pancolitis for UC and ileitis and ileocolitis for CD. All groups were compared for mean serum B2-M levels and also examined to see whether there was a correlation between serum B2-M levels and other inflammatory markers.RESULTS: The mean serum B2-M levels in the control group, UC and CD were 1.71, 2.41 and 2.24 respectively. B2-M values ≥ 1.96 mg/L had a 62% sensitivity, 76% specificity, a 79% positive predictive value, and a 58% negative predictive value for UC patients. B2-Mvalues ≥ 1.70 mg/L had 80% sensitivity, 53% specificity, 66% positive predictive value, and 69% negative predictive value for CD patients. Mean B2-M values were significantly higher in ulcerative colitis and Crohn's disease patients than in healthy controls(UC 2.41 ± 0.87 vs 1.71 ± 0.44, P = 0.002; CD 2.24 ± 1.01 vs 1.71 ± 0.44, P = 0.033). Also, mean B2-M values were significantly higher in active disease when compared to patients in remission(UC 2.66 ± 0.92 vs 1.88 ± 0.41, P = 0.004; CD 2.50 ± 1.15 vs 1.73 ± 0.31, P = 0.033). The difference between groups(UC and CD) in terms of serum B2-M levels was statistically insignificant(2.41 ± 0.87 vs 2.24 ± 1.01, P > 0.05 respectively).CONCLUSION: Serum B2-M levels may be used as an activity parameter in IBD. | Bülent Y|lmaz Seyfettin Kklü Osman Yüksel Serap Arslan | 2014 | World Journal of Gastroenterology2014，20，31： | 3 |
| 2 | Fluorescence-based sensor for Pb(Ⅱ)using tetra-(3-bromo-4-hydroxyphenyl)porphyrin in liquid and immobilized medium显示文摘 | Serap S B Sevda A Ipek K | 2009 | Spectrochimica Acta Part A2009，72，2： | 1 |
| 3 | Acute respiratory failure and tracheal obstruction in patients with posterior giant mediastinal (intrathoracic) goiter 显示文摘 | SERAP K OMER O TULAY O | 2004 | Inter Card ThorSurg2004，3，： | 1 |
| 4 | A decomposition analysis of CO 2 emissions from energy use: Turkish case显示文摘 | G. ?pek Tun? Serap Türüt-A??k Elif Akbostanc? | 2009 | Energy Policy2009，，11： | 1 |
| 5 | The estimation of NMVOC emissions from an urban-scale wastewater treatment plant显示文摘 | ELIF A TUNCAY D SERAP K | 2004 | Water Research2004，38，1415： | 1 |
| 6 | Cerebral blood flow abnormalities in symptomatic West syndrome:a single photon emission computed tomography study显示文摘 | Gulhis D Serap U | 2001 | Pediatr Intern2001，43，： | 1 |
| 7 | Acute respiratoy failure and tracheal obstruction in patients with posteriao giant mediastinal (intrathoracic) goiter 显示文摘 | Serap K Omer O Tulay O | 2004 | Interactive Cardiovascular Thoracic Surgery2004，3，： | 1 |
| 8 | Monitoring of nuclear abnormalities in peripheral erythrocytes of three fish species from the Goksu Delta (Turkey): genotoxic damage in relation to water pollution显示文摘 | Serap Ergene Tolga ?ava? Ayla ?elik Nurcan K?leli Filiz Kaya Arzu Karahan | 2007 | Ecotoxicology2007，，4： | 1 |
| 9 | Mucopolysaccharidosis: Otolaryngologic findings, obstructive sleep apnea and accumulation of glucosaminoglycans in lymphatic tissue of the upper airway显示文摘 | Burhanettin G?nülda? Taner Y?lmaz H. Serap Sivri K. ?afak Gü?er Kamer K?l?n? G. Aydan Gen? Mustafa K?l?? Turgay Co?kun | 2014 | International Journal of Pediatric Otorhinolaryngology2014，，6： | 1 |
| 10 | Congenital thoracic arterial anomalies in adults: ACT overview 显示文摘 | Afra Y Nevzat K Serap D | 2011 | Diagn Interv Radiol2011，17，4： | 1 |
| 11 | Human bocavirus infection in children hospitalized with lower respiratory tract infections:Does viral load affect disease course?显示文摘Objective:To examine the effects of human bocavirus type 1(HBoV1)on the course of lower respiratory tract infections in cases of monoinfection and coinfection,and the effects of HBoV1 viral load on the disease in children under six years old hospitalized with a diagnosis of HBoV1-associated lower respiratory tract infections.Methods:Children under six years of age,who were hospitalized with the diagnosis of lower respiratory tract infection due to HBoV1 between 1 January 2021 and 1 January 2022 were included in the study.Laboratory confirmation of the respiratory pathogens was performed using polymerase chain reaction(PCR).Results:Fifty-four(16.4%)children with HBoV1 among 329 children whose PCR was positive with bacterial/viral agent in nasopharyngeal swab samples were included in the study.There were 28(51.9%)males and 26(48.1%)females with a median age 23.4 months[interquartile range(IQR):13.2,30.0 months](min-max:1 month-68 months).HBoV1 was detected as a monoinfecton in 26(48.1%)children,and as a coinfection with other respiratory agents in 28 children(51.9%).In multiple regression analysis,coinfection(P=0.032)was associated with the length of hospitalization(P<0.001;R^(2)=0.166).There was a negative correlation(r=−0.281,P=0.040)between cough and cycle threshold.Fever was found to be positively correlated with C-reactive protein(r=0.568,P<0.001)and procalcitonin(r=0.472;P=0.001).Conclusions:Although we found a higher HBoV1 viral load in children with more cough symptoms in our study,it had no effect on the severity of the disease,such as length of hospital stay and need for intensive care.Coinfection was found to affect the length of hospitalization. | Ayşe Karaaslan CerenÇetin Serap Demir Tekol Ufuk Yükselmiş Mehmet Tolga Köle Yasemin Akın | 2022 | Asian Pacific Journal of Tropical Medicine2022，15，8： | 1 |
| 12 | Cervical vestibular evoked myogenic potentials to air-conducted sound in early amyotrophic lateral sclerosis显示文摘 | Kiliu S Gazioglu S Serap Zengin K | 2012 | Neurophysiol Clin2012，42，3： | 1 |
| 13 | Cerebral blood flow abnormalities in symptomatic West syndrome:a single photon emission computed tomography study显示文摘 | Ugur K Gūlhis D Serap U | 2001 | Pediatr Intern2001，43，： | 1 |
| 14 | Fluorescence-based sensor for Pb(Ⅱ)using tetra-(3-bromo-4 - hydroxyphenyl)porphyrin in liquid and immobilized medium显示文摘 | Serap S B Sevda A Ipek K | 2009 | Spectroehimica Acta Part A2009，72，2： | 1 |
| 15 | Clinical update on pulmonary embolism显示文摘 | Serap D Arif K SadiK A | 2014 | Archives of Medical Science Ams2014，10，3： | 1 |
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