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| 1 | Lithofacies palaeogeography of the Carboniferous and Permian in the Qinshui Basin, Shanxi Province, China显示文摘The Qinshui Basin in the southeastern Shanxi Province is an important area for coalbed methane(CBM) exploration and production in China, and recent exploration has revealed the presence of other unconventional types of gas such as shale gas and tight sandstone gas. The reservoirs for these unconventional types of gas in this basin are mainly the coals, mudstones, and sandstones of the Carboniferous and Permian; the reservoir thicknesses are controlled by the depositional environments and palaeogeography. This paper presents the results of sedimentological investigations based on data from outcrop and borehole sections, and basin-wide palaeogeographical maps of each formation were reconstructed on the basis of the contours of a variety of lithological parameters. The palaeogeographic units include the depositional environments of the fluvial channel, flood basin(lake), upper delta plain, lower delta plain, delta front, lagoon, tidal flat, barrier bar, and carbonate platform.The Benxi and Taiyuan Formations are composed mainly of limestones, bauxitic mudstones,siltstones, silty mudstones, sandstones, and economically exploitable coal seams, which were formed in delta, tidal flat, lagoon, and carbonate platform environments. The Shanxi Formation consists of sandstones, siltstones, mudstones, and coals; during the deposition of the formation, the northern part of the Qinshui Basin was occupied mainly by an upper delta plain environment, while the central and southern parts were mainly occupied by a lower delta plain environment and the southeastern part by a delta front environment. Thick coal zones occur in the central and southern parts, where the main depositional environment was a lower delta plain. The thick coal zones of the Taiyuan Formation evidently occur in the sandstone-rich belts, located mainly in the lower delta plain environment in the northern part of the basin and the barrier bar environments in the southeastern part of the basin. In contrast, the thick coal zones of the Shanxi Formation extend over the mudstone-rich belts, located in the areas of the lower delta plain environments of the central and southern parts of the Basin.The Xiashihezi, Shangshihezi, and Shiqianfeng Formations consist mainly of red mudstones with thick-interbedded sandstones. During the deposition of these formations, most areas of the basin were occupied by a fluvial channel, resulting in palaeogeographic units that include fluvial channel zones and flood basins. The fluvial channel deposits consist mainly of relatively-thick sandstones, which could have potential for exploration of tight sandstone gas. | Long-Yi Shao Zhi-Yu Yang Xiao-Xu Shang Zheng-Hui Xiao Shuai Wang Wen-Long Zhang Ming-Quan Zheng Jing Lu | 2015 | Journal of Palaeogeography2015，4，4： | 21 |
| 2 | Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke显示文摘Atorvastatin decreases inflammation and thrombogenesis in patients with carotid artery plaque. Atorvastatin is administered to lower lipid levels, but its anti-inflammatory and anti-thrombogenic effects remain unclear. Eighty-nine patients from northeastern China with acute ischemic stroke caused by large-artery atherosclerosis were randomly divided into the study and control groups. All patients received routine treatment, including antiplatelet therapy, circulatory support, and symp-tomatic treatment. The study group (n=43) also received daily atorvastatin 20 mg/d, and the control group (n=46) received daily placebo pills containing glucose. After 4 weeks, the levels of C-reactive protein, fibrinogen, and D-dimer were significantly lower in the study group than in the control group. Decreases in the levels of C-reactive protein, fibrinogen, and D-dimer were not associated with de-creases in the levels of triacylglycerol and low-density lipoprotein cholesterol. These results suggest that atorvastatin reduces inflammation and thrombogenesis independent of its lipid-lowering effects in patients with acute ischemic stroke caused by large-artery atherosclerosis. | Lianqiu Min Shuai Shao Xiaoning Wu Lin Cong Ping Liu Haiping Zhao Yumin Luo | 2013 | Neural Regeneration Research2013，8，23： | 19 |
| 3 | Highly-Sensitive Multiplexed in vivo Imaging Using PEGylated Upconversion Nanoparticles显示文摘Lanthanide-based upconversion nanoparticles(UCNPs)have been widely explored in various fields,including optical imaging,in recent years.Although earlier work has shown that UCNPs with different lanthanide(Ln3+)dopants exhibit various colors,multicolor-especially in vivo multiplexed biomedical imaging-using UCNPs has rarely been reported.In this work,we synthesize a series of UCNPs with different emission colors and functionalize them with an amphiphilic polymer to confer water solubility.Multicolor in vivo upconversion luminescence(UCL)imaging is demonstrated by imaging subcutaneously injected UCNPs and applied in multiplexed in vivo lymph node mapping.We also use UCNPs for multicolor cancer cell labeling and realize in vivo cell tracking by UCL imaging.Moreover,for the first time we compare the in vivo imaging sensitivity of quantum dot(QD)-based fluorescence imaging and UCNP-based UCL imaging side by side,and find the in vivo detection limit of UCNPs to be at least one order of magnitude lower than that of QDs in our current non-optimized imaging system.Our data suggest that,by virtue of their unique optical properties,UCNPs have great potential for use in highly-sensitive multiplexed biomedical imaging. | Liang Cheng Kai Yang Shuai Zhang Mingwang Shao Shuittong Lee Zhuang Liu | 2010 | Nano Research2010，3，10： | 17 |
| 4 | Changing Proportions of HIV-1 Subtypes and Transmitted Drug Resistance Among Newly Diagnosed HIV/AIDS Individuals—China,2015 and 2018显示文摘Introduction:With the expansion of human immunodeficiency virus(HIV)antiretroviral therapy(ART),HIV drug resistance is becoming more and more serious.This study describes the changing prevalence of HIV-1 subtypes and transmitted drug resistance(TDR)among newly diagnosed individuals in China,2015 and 2018.Methods:A total of 8,980 individuals in 2015 and 2018 from 31 provincial-level administrative divisions(PLADs)were enrolled in this study.Viral RNAs were amplified and sequenced using an in-house polymerase chain reaction(PCR)protocol.The Stanford HIV Drug Resistance Database(HIVdb)was used to predict susceptibility to 12 antiretroviral drugs.Results:The prevalence of TDR was not significantly increased over time.The prevalence of TDR was 3.8%and 4.4%in 2015 and 2018,respectively(P=0.13).The prevalence of CRF55_01B increased from 2.3%in 2015 to 3.9%in 2018(P<0.001).The drug resistance prevalence of nonnucleoside reverse transcriptase inhibitors(NNRTI)increased from 2.4%in 2015 to 3.3%in 2018(P<0.01).The prevalence of E138(P<0.001),H221(P=0.03),and V179(P<0.001)mutations increased from 0.30%,0.09%,and 0.70%in 2015 to 1.10%,0.30%,and 1.70%in 2018,respectively.Conclusions:HIV drug resistance affects the effect of antiretroviral treatment,so the monitoring of HIV TDR should be strengthened to control the transmission of HIV drug resistance. | Jingjing Hao Shan Zheng Mengze Gan Aobo Dong Ruihua Kang Miaomiao Li Shuai Zhao Jing Hu Chang Song Lingjie Liao Yi Feng Yiming Shao Yuhua Ruan Hui Xing | 2021 | China CDC weekly2021，3，53： | 13 |
| 5 | Sequence stratigraphy, paleogeography, and coal accumulation regularity of major coal-accumulating periods in China显示文摘There are 9 major coal-accumulating periods during geological history in China,including the Early Carboniferous,Late Carboniferous-Early Permian,Middle Permian,Late Permian,Late Triassic,Early-Middle Jurassic,Early Cretaceous,Paleogene and Neogene.The coal formed in these periods were developed in different coal-accumulating areas(CAA)including the North China,South China,Northwest China,Northeast China,the Qinghai–Tibet area,and China offshore area.In this paper,we investigated depositional environments,sequence stratigraphy,lithofacies paleogeography and coal accumulation pattern of five major coal-accumulating periods including the Late Carboniferous to Middle Permian of the North China CAA,the Late Permian of the South China CAA,the Late Triassic of the South China CAA,the Early-Middle Jurassic of the North and Northwest China CAA,and the Early Cretaceous in the Northeast China CAA.According to distribution of the coal-bearing strata and the regional tectonic outlines,we have identified distribution range of the coal-forming basins,sedimentary facies types and coal-accumulating models.The sequence stratigraphic frameworks of the major coal-accumulating periods were established based on recognition of a variety of sequence boundaries.The distribution of thick coals and migration patterns of the coal-accumulating centers in the sequence stratigraphic framework were analyzed.The lithofacies paleogeography maps based on third-order sequences were reconstructed and the distribution of coal accumulation centers and coal-rich belts were predicted. | Longyi Shao Xuetian Wang Dongdong Wang Mingpei Li Shuai Wang Yingjiao Li Kai Shao Chao Zhang Caixia Gao Daxiao Dong Aiguo Cheng Jing Lu Congwei Ji Di Gao | 2020 | International Journal of Coal Science & Technology2020，7，2： | 9 |
| 6 | Characteristics of Early Cretaceous wildfires in peat-forming environment, NE China显示文摘Inertinite maceral compositions in coals from the Early Cretaceous Erlian, Hailar, and Sanjiang Basins in NE China are analyzed in order to reveal palaeowildfire events and palaeoclimate variations. Although huminite is the dominant maceral group in the studied basins, the inertinite group, as a byproduct of palaeowildfires, makes up a considerable proportion. Occurrence of inertinite macerals indicates that wildfires were widespread and frequent,and supports the opinion that the Early Cretaceous was a 'high-fire' interval. Inertinite contents vary from 0.2% to 85.0%, mostly within the range of 10%–45%, and a model-based calculation suggests that the atmospheric oxygen levels during the Aptian and Albian(Early Cretaceous) were around 24.7% and 25.3% respectively. Frequent fire activity during Early Cretaceous has been previously related to higher atmospheric oxygen concentrations. The inertinite reflectance, ranging from 0.58%Ro to 2.00%Ro, indicates that the palaeowildfire in the Early Cretaceous was dominated by ground fires, partially reaching-surface fires. These results further support that the Cretaceous earliest angiosperms from NE China were growing in elevated O2 conditions compared to the present day. | Shuai Wang Long-Yi Shao Zhi-Ming Yan Ming-Jian Shi Yun-He Zhang | 2019 | Journal of Palaeogeography2019，8，3： | 7 |
| 7 | Rational design of MoS_(2) nanosheets decorated on mesoporous hollow carbon spheres as a dual-functional accelerator in sulfur cathode for advanced pouch-type Li–S batteries显示文摘Developing sulfur cathodes with high catalytic activity on accelerating the sluggish redox kinetics of lithium polysulfides(Li PSs) and unveiling their mechanisms are pivotal for advanced lithium–sulfur(Li–S)batteries. Herein, MoS2 is verified to reduce the Gibbs free energy for rate-limiting step of sulfur reduction and the dissociation energy of lithium sulfide(Li2 S) for the first time employing theoretical calculations. The Mo S2 nanosheets coated on mesoporous hollow carbon spheres(MHCS) are then reasonably designed as a sulfur host for high-capacity and long-life Li–S battery, in which MHCS can guarantee the high sulfur loading and fast electron/ion transfer. It is revealed that the shuttle effect is efficiently inhibited because of the boosted conversion of Li PSs. As a result, the coin cell based on the MHCS@Mo S2-S cathode exhibits stable cycling performance maintaining 735.7 mAh g^(-1) after 500 cycles at 1.0 C. More importantly, the pouch cell employing the MHCS@Mo S2-S cathodes achieves high specific capacity of1353.2 m Ah g^(-1) and prominent cycle stability that remaining 960.0 m Ah g^(-1) with extraordinary capacity retention of 79.8% at 0.1 C after 170 cycles. Therefore, this work paves a new avenue for developing practical high specific energy and long-life pouch-type Li–S batteries. | Qinjun Shao Pengfei Lu Lei Xu Decai Guo Jing Gao Zhong Shuai Wu jian Chen | 2020 | Journal of Energy Chemistry2020，29，12： | 7 |
| 8 | Arm Voltage Balancing Control of Modular Multilevel Resonant Converter显示文摘Modular multilevel resonant converter is an promising candidate for high voltage applications since it has advantageous features,such as high efficiency,high voltage capability and easy fault-tolerant operation.However,the inequality of arm inductance in practice will lead to imbalance between the upper and lower arm voltages,which will induce large ripples in the circulating current and a dc bias on the voltage generated by modular circuits.To compensate for the voltage imbalance,effects of arm duty cycle changes on arm voltages are discussed.An arm voltage balancing control method is proposed:adjust arm duty cycle according to arm voltage deviation in every switching cycle.Simulation and experimental results are presented to validate the theoretical analysis and the proposed control method. | Jianjia Zhang Shuai Shao Yucen Li Junming Zhang Kuang Sheng | 2020 | CES Transactions on Electrical Machines and Systems2020，4，4： | 7 |
| 9 | Aconapelsulfonines A and B,seco C_(20)-diterpenoid alkaloids deriving via Criegee rearrangements of napelline skeleton from Aconitum carmichaelii显示文摘Two sulfo nated seco C_(20)-diterpenoid alkaloids,aconapelsulfonines A(1) and B(2),were isolated from an aqueous extract of the raw material of 'Fu Zi'(the Aconitum carmichaelii lateral roots),of which the structures were elucidated by various spectroscopic data,combined with X-ray crystallogra phic analysis.The unprecedented skeletons are biogenetically proposed to be derived via Criegee rearrangements of the napelline-type architecture.The two compounds exhibited dose-depended analgesic activities on an acetic acid-induced mice writhing test. | Hui Liu Yuzhuo Wu Qinglan Guo Shuai Shao Chengbo Xu Tiantai Zhang Jiangong Shi | 2021 | Chinese Chemical Letters2021，32，1： | 6 |
| 10 | MicroRNA expression profile and functional analysis reveal their roles in contact inhibition and its disruption switch of rat vascular smooth muscle cells显示文摘接触抑制和它脉管的光滑的肌肉房间(VSMC ) 的混乱是在脉管的疾病的重要细胞的事件。但是内在的分子的机制是不清楚的。在这研究,我们在接触抑制和它 VSMC 和包含的分子的机制的混乱调查了 microRNAs (miRNAs ) 的角色。老鼠 VSMC 在 30% 或 90% 融合被播种。在禁止接触的 conuent VSMC (90% 融合) 和 non-contact-inhibited 的 MiRNA 表示侧面低密度的 VSMC (30% 融合) 被决定。我们发现多重 miRNAs 是在二个组之间表示的差别。在他们之中, miR-145 显著地在禁止接触的 VSMC 被增加。浆液能破坏由 conuent VSMC 的得到的增长出现的接触抑制。伴有 miR-145 的一条下面规定的接触抑制混乱。VSMC 的导致浆液的接触抑制混乱被 miR-145 的 overexpression 堵住。而且, miR-145 的 downregulation 是足够的破坏 VSMC 的接触抑制。在导致浆液的接触抑制混乱的 miR-145 的 downregulation 与激活 PI3-kinase/Akt 小径有关,它被 PI3-kinase 禁止者 LY294002 堵住。KLF5, miR-145 的目标基因,被识别在 VSMC 接触抑制混乱上涉及 miR-145-mediated 效果,,它能被禁止由 KLF5 击倒。在摘要,我们的结果证明多重 miRNAs 是在禁止接触的 VSMC 并且在 non-contact-inhibited VSMC 表示的差别。在他们之中, miR-145 是在接触抑制和它 VSMC 的混乱的批评基因。PI3-kinase/Akt/miR-145/KLF5 是在导致浆液的接触抑制混乱的一条批评发信号小径。与 VSMC 的接触抑制有关的 miRNAs 指向可以为脉管的疾病代表一条新奇治疗学的途径。 | Ye-ying SUN Shan-shan QIN Yun-hui CHENG Chao-yun WANG Xiao-jun LIU Ying LIU Xiu-li ZHANG Wendy ZHANG Jia-xin ZHAN Shuai SHAO Wei-hua BIAN Bi-hui LUO Dong-feng LU Jian YANG Chun-hua WANG Chun-xiang ZHANG | 2018 | Acta Pharmacologica Sinica2018，39，5： | 5 |
| 11 | Application of VP1 Protein to Develop Monoclonal Antibody against Foot-and-mouth Disease Virus Asia1 Type显示文摘In order to develop an anti-FMDV Asia1 type monoclonal antibody(mAb) ,BABL/c mice were immunized with recombinant FMDV VP1 protein. Three mAbs,1B8,5E1 and 5E2,were then further optimized. The result indicated that prepared anti-FMDV Asia1 mAbs had no cross-reactivity with Swine vesicular disease(SVD) and FMDV O,A and C type antigen. Their titers in abdomen liquor were 1:5×106,1:2×106 and 1:5×106,respectively. 1B8 was found to be of IgG1 subtype,5E1 and 5E2 belonged to IgG2b subtype. In this study,the prepared mAbs are specific for detecting FMDV type Asia1,and is potentially useful for pen-side diagnosis. | Tong LIN Jun-zheng DU Jun-jun SHAO Guo-zheng CONG Shuai SONG Shan-dian GAO Hui-yun CHANG | 2009 | Virologica Sinica2009，24，3： | 5 |
| 12 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 13 | Antimicrobial peptides:bridging innate and adaptive immunity in the pathogenesis of psoriasis显示文摘Antimicrobial peptides(AMPs)are small molecules produced by a myriad of cells and play important roles not only in protecting against infections and sustaining skin barrier homeostasis but also in contributing to immune dysregulation under pathological conditions.Recently,increasing evidence has indicated that AMPs,including cathelicidin(LL-37),humanβ-defensins,S100 proteins,lipocalin 2,and RNase 7,are highly expressed in psoriatic skin lesions.These peptides broadly regulate immunity by interacting with various immune cells and linking innate and adaptive immune responses during the progression of psoriasis.In this review,we summarize the recent findings regarding AMPs in the pathogenesis of psoriasis with a main focus on their immunomodulatory abilities. | Jing-Yi Ma Shuai Shao Gang Wang | 2020 | Chinese Medical Journal2020，，24： | 5 |
| 14 | Dry reforming of methane by microsecond pulsed dielectric barrier discharge plasma:Optimizing the reactor structures显示文摘Dry reforming of CH4 process can convert greenhouse gases into high-value-added fuels and chemicals with its broad application prospects in environmental protection and renewable energy.Non-thermal plasma is considered an effective alternative method because it can activate CH4 and CO_(2)under low temperature and atmospheric pressure.This paper is aimed to optimize the plasma-assisted dry reforming of CH4 process in a unipolar microsecond pulsed coaxial dielectric barrier discharge by inves-tigating the effects of reactor structures.The results show that the conversions of re-actants and the yields of syngas were significantly affected by the reactor structures.Specifically,a multi-stage or foil external electrode and negative polar discharge could promote CH4 and CO_(2)conversions,gas product yields,and energy conversion efficiencies.For different electrodes,the maximal conversions of CH4 and CO_(2)were 20.4%and 14.1%,with an energy conversion efficiency of 4.4%under our experimental conditions.Higher conversions,yields,and energy conversion efficiencies were obtained with lower power input when applying heat insulation measures.CH4 conversion was promoted to 27.9%with a moderate energy conversion efficiency of 3.8%,but the conversion of CO_(2)was only 12%when packing materials into the reactor.The results can provide specific guidance for designing plasma or plasma-catalytic dry reforming reactor. | Shuai Zhang Yuan Gao Hao Sun Zhe Fan Tao Shao | 2022 | High Voltage2022，7，4： | 5 |
| 15 | Giant Landslides Triggered by the 1718 Tongwei Earthquake in Pan'an, Gansu Province, China显示文摘Great earthquakes in mountain areas always trigger severe geologic hazards such as landslides,debris flows and rock falls,thereby causing tremendous property damage and casualties.On 19th June,1781,a Ms 7.5earthquake occurred in Tongwei of Pan’an,Gansu Province,west China,and triggered more than | SUN Ping SHAO Tiequan SHI Jusong ZHANG Shuai MENG Jing | 2015 | Acta Geologica Sinica(English Edition)2015，89，1： | 5 |
| 16 | Influence of depositional environment on coalbed methane accumulation in the Carboniferous-Permian coal of the Qinshui Basin, northern China显示文摘Based on analyses of the lithofacies palaeo-geography of the Taiyuan and the Shanxi Formations in the Qinshui Basin, the spatial variations of the coal seam thickness, coal maceral composition, coal quality, and gas content, together with the lithofacies of the surrounding rocks in each palaeogeographic unit were investigated. The results show that the thick coals of the Taiyuan Formation are mainly distributed in delta and barrier island depositional units in the Yangquan area in the northern part of the basin and the Zhangzi area in the southeastern part of the basin. The thick coals of the Shanxi Formation are located within transitional areas between delta plain and delta front depositional units in the central southern part of the basin. The Taiyuan Formation generally includes mudstone in its lower part, thick, continuous coal seams and limestones in its middle part, and thin, discontinuous coal seams and limestone and sand-mud interbeds in its top part. The Shanxi Formation consists of thick, continuous sandstones in its lower part, thick coal seams in its middle part, and thin coal seams, sandstone, and thick mudstone in its upper part. From the perspective of coal-bearing sedimentology and coalbed methane (CBM) geology, the lithology and thickness of the surrounding rocks of coal seams play more significant roles in controlling gas content variation than other factors such as coal thickness, coal macerals, and coal quality. Furthermore, it is found that the key factors influencing the gas content variation are the thicknesses of mudstone and limestone overlying a coal seam. At similar burial depths, the gas content of the Taiyuan coal seams decreases gradually in the lower delta plain, barrier-lagoon,delta front, barrier-tidal flat, and carbonate platform depositional units. The CBM enrichment areas tend to be located in zones of poorly developed limestone and well-developed mudstone. In addition, the gas content of the Shanxi Formation is higher in the coals of the delta front facies compared to those in the lower delta plain. The CBM enrichment areas tend to be associated with the thicker mudstones. Therefore, based on the lithologic distribution and thickness of the rocks overlying the coal seam in each palaeogeographic unit of the Taiyuan and Shanxi Formations, the areas with higher gas content are located in the north-central basin for the Taiyuan coals and in the southern basin for the Shanxi coals. Both of these areas should be favorable for CBM exploration in the Qinshui Basin. | Haihai HOU Longyi SHAO Shuai WANG Zhenghui XIAO Xuetian WANG Zhen LI | 2019 | Frontiers of Earth Science2019，13，3： | 4 |
| 17 | Morphology and composition of particles emitted from a port fuel injection gasoline vehicle under real-world driving test cycles显示文摘Traffic vehicles, many of which are powered by port fuel injection(PFI) engines, are major sources of particulate matter in the urban atmosphere. We studied particles from the emission of a commercial PFI-engine vehicle when it was running under the states of cold start, hot start, hot stabilized running, idle and acceleration, using a transmission electron microscope and an energy-dispersive X-ray detector. Results showed that the particles were mainly composed of organic, soot, and Ca-rich particles, with a small amount of S-rich and metal-containing particles, and displayed a unimodal size distribution with the peak at 600 nm. The emissions were highest under the cold start running state, followed by the hot start, hot stabilized, acceleration, and idle running states. Organic particles under the hot start and hot stabilized running states were higher than those of other running states. Soot particles were highest under the cold start running state. Under the idle running state, the relative number fraction of Ca-rich particles was high although their absolute number was low. These results indicate that PFI-engine vehicles emit substantial primary particles,which favor the formation of secondary aerosols via providing reaction sites and reaction catalysts, as well as supplying soot, organic, mineral and metal particles in the size range of the accumulation mode. In addition, the contents of Ca, P, and Zn in organic particles may serve as fingerprints for source apportionment of particles from PFI-engine vehicles. | Jiaoping Xing Longyi Shao Wenbin Zhang Jianfei Peng Wenhua Wang Cong Hou Shijin Shuai Min Hu Daizhou Zhang | 2019 | Journal of Environmental Sciences2019，31，2： | 4 |
| 18 | A new derivative of triterpene with anti-melanoma B16 activity from Conyza canadensis显示文摘A new derivative of triterpene named Erigeronol 1 was isolated from the EtOH extract of the aerial part of Conyza canadensis together with 15 known compounds for the first time from this plant.The structure of Erigeronol 1 was elucidated as 3-O-(hydroxyacetyl) -23,28-dihydroxy-β-amyrin by hydrolysis and spectroscopic analysis.Erigeronol 1 showed potent cytotoxic activity with IC_(50) value of 7.77±0.47μg/mL against melanoma B16 determined by the 3-(4,5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide(MTT) method. | Ming Ming Yan Ting You Li Da Qing Zhao Shuai Shao Sheng Nan Bi | 2010 | Chinese Chemical Letters2010，21，7： | 4 |
| 19 | A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2显示文摘The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying asymptomatic and presymptomatic carriers of the virus,and thus highlights a strong motivation for diagnostics with high sensitivity that can be rapidly deployed.On the other hand,several concerning SARS-CoV-2 variants,including Omicron,are required to be identified as soon as the samples are identified as‘positive’.Unfortunately,a traditional PCR test does not allow their specific identification.Herein,for the first time,we have developed MOPCS(Methodologies of Photonic CRISPR Sensing),which combines an optical sensing technology-surface plasmon resonance(SPR)with the‘gene scissors’clustered regularly interspaced short palindromic repeat(CRISPR)technique to achieve both high sensitivity and specificity when it comes to measurement of viral variants.MOPCS is a low-cost,CRISPR/Cas12a-systemempowered SPR gene-detecting platform that can analyze viral RNA,without the need for amplification,within 38 min from sample input to results output,and achieve a limit of detection of 15 fM.MOPCS achieves a highly sensitive analysis of SARS-CoV-2,and mutations appear in variants B.1.617.2(Delta),B.1.1.529(Omicron)and BA.1(a subtype of Omicron).This platform was also used to analyze some recently collected patient samples from a local outbreak in China,identified by the Centers for Disease Control and Prevention.This innovative CRISPR-empowered SPR platform will further contribute to the fast,sensitive and accurate detection of target nucleic acid sequences with single-base mutations. | Zhi Chen Jingfeng Li Tianzhong Li Taojian Fan Changle Meng Chaozhou Li Jianlong Kang Luxiao Chai Yabin Hao Yuxuan Tang Omar AAl-Hartomy Swelm Wageh Abdullah GAl-Sehemi Zhiguang Luo Jiangtian Yu Yonghong Shao Defa Li Shuai Feng William J.Liu Yaqing He Xiaopeng Ma Zhongjian Xie Han Zhang | 2022 | National Science Review2022，9，8： | 3 |
| 20 | Evaluation of Wind Retrieval from Co-Polarization Gaofen-3 SAR Imagery Around China Seas显示文摘Gaofen-3(GF-3) is the first Chinese space-borne satellite to carry the C-band multi-polarization synthetic aperture radar(SAR). Marine applications, i.e., winds and waves retrieved from GF-3 SAR images, have been operational since January 2017. In this study, we have collected more than 1000 quad-polarization(vertical-vertical(VV); horizontal-horizontal(HH); vertical-horizontal(VH); horizontal-vertical(HV)) GF-3 SAR images, which were acquired around the China Seas from September 2016 to September 2017. Wind streaks were visible in these images in co-polarization(VV and HH) channel. Geophysical model functions(GMFs), including the CMOD5N together with polarization ratio(PR) model and C-SARMOD, were used to retrieve winds from the collected co-polarization GF-3 SAR images. Wind directions were directly obtained from GF-3 SAR images. Then, the SAR-derived wind speeds were compared with the measurements at a 0.25? grid from the Advanced Scatterometer on board the Metop-A/B and microwave radiometer WindSAT. Based on the analysis, empirical corrections are proposed to improve the performance of the two GMFs. Results of this study show that the standard deviation of wind speed is 1.63 m s^(-1) with a 0.19 m s^(-1) bias and 1.71 m s^(-1) with a 0.26 m s^(-1) bias for VV-and HH-polarization GF-3 SAR, respectively. Our work not only systematically evaluates wind retrieval by using the two advanced GMFs and PR models but also proposes empirical corrections to improve the accuracy of wind retrievals from GF-3 SAR images around the China Seas and thus enhance the accuracy of near real-time operational SAR-derived wind products. | SHAO Weizeng ZHU Shuai SUN Jian YUAN Xinzhe SHENG Yexin ZHANG Qingjun JI Qiyan | 2019 | Journal of Ocean University of China2019，18，1： | 3 |
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