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| 1 | False data injection attacks against smart grid state estimation:Construction, detection and defense显示文摘As a typical representative of the so-called cyber-physical system,smart grid reveals its high efficiency,robustness and reliability compared with conventional power grid.However,due to the deep integration of electrical components and computinginformation in cyber space,smart grid is vulnerable to malicious attacks,especially for a type of attacks named false data injection attacks(FDIAs).FDIAs are capable of tampering meter measurements and affecting the results of state estimation stealthily,which severely threat the security of smart grid.Due to the significantinfluence of FDIAs on smart grid,the research related to FDIAs has received considerable attention over the past decade.This paper aims to summarize recent advances in FDIAs against smart grid state estimation,especially from the aspects of background materials,construction methods,detection and defense strategies.Moreover,future research directions are discussed and outlined by analyzing existing results.It is expected that through the review of FDIAs,the vulnerabilities of smart grid to malicious attacks can be further revealed and more attention can be devoted to the detection and defense of cyber-physical attacks against smart grid. | ZHANG Meng SHEN Chao HE Ning HAN SiCong LI Qi WANG Qian GUAN XiaoHong | 2019 | Science China(Technological Sciences)2019，62，12： | 6 |
| 2 | Adaptive optics two-photon microscopy enables near-diffraction-limited and functional retinal imaging in vivo显示文摘In vivo fundus imaging offers non-invasive access to neuron structures and biochemical processes in the retina.However,optical aberrations of the eye degrade the imaging resolution and prevent visualization of subcellular retinal structures.We developed an adaptive optics two-photon excitation fluorescence microscopy(AO-TPEFM)system to correct ocular aberrations based on a nonlinear fluorescent guide star and achieved subcellular resolution for in vivo fluorescence imaging of the mouse retina.With accurate wavefront sensing and rapid aberration correction,AOTPEFM permits structural and functional imaging of the mouse retina with submicron resolution.Specifically,simultaneous functional calcium imaging of neuronal somas and dendrites was demonstrated.Moreover,the timelapse morphological alteration and dynamics of microglia were characterized in a mouse model of retinal disorder.In addition,precise laser axotomy was achieved,and degeneration of retinal nerve fibres was studied.This highresolution AO-TPEFM is a promising tool for non-invasive retinal imaging and can facilitate the understanding of a variety of eye diseases as well as neurodegenerative disorders in the central nervous system. | Zhongya Qin Sicong He Chao Yang Jasmine Sum-Yee Yung Congping Chen Christopher Kai-Shun Leung Kai Liu Jianan Y.Qu | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 3 | Traditional Chinese medicine molecule-assisted chemical synthesis of fluorescent anti-cancer silicon nanoparUcles显示文摘 | Xiaoyuan Ji Daoxia Guo Bin Song Sicong Wu Binbin Chu Yuanyuan Su Yao He | 2018 | Nano Research2018，11，10： | 3 |
| 4 | High-resolution two-photon transcranial imaging of brain using direct wavefront sensing显示文摘Imaging of the brain in its native state at high spatial resolution poses major challenges to visualization techniques.Two-photon microscopy integrated with the thinned-skull or optical clearing skull technique provides a minimally invasive tool for in vivo imaging of the cortex of mice without activating immune response and inducing brain injury.However,the imaging contrast and spatial resolution are severely compromised by the optical heterogeneity of the skull,limiting the imaging depth to the superficial layer.In this work,an optimized configuration of an adaptive optics two-photon microscope system and an improved wavefront sensing algorithm are proposed for accurate correction for the aberrations induced by the skull window and brain tissue.Using this system,we achieved subcellular resolution transcranial imaging of layer 5 pyramidal neurons up to 700μm below pia in living mice.In addition,we investigated microglia–plaque interaction in living brain of Alzheimer’s disease and demonstrated high-precision laser dendrotomy and single-spine ablation. | CONGPING CHEN ZHONGYA QIN SICONG HE SHAOJUN LIU SHUN-FAT LAU WANJIE WU DAN ZHU NANCY Y.IP JIANAN Y.QU | 2021 | Photonics Research2021，9，6： | 2 |
| 5 | An intravenous clarithromycin lipid emulsion with a high drug loading, H-bonding and a hydrogen-bonded ion pair complex exhibiting excellent antibacterial activity显示文摘The aim of this study was to develop an intravenous clarithromycin lipid emulsion(CLE)with good stability and excellent antibacterial activity. The CLE was prepared by the thinfilm dispersed homogenization method. The interaction between clarithromycin(CLA) and cholesteryl hemisuccinate(CHEMS) was confirmed by DSC, FT-IR and^1H NMR analysis. The interfacial drug loading, thermal sterilization, freeze–thaw stability, and in vitro and in vivo antibacterial activity were investigated systematically. DSC, FT-IR and^1H NMR spectra showed that CHEMS(CLA: CHEMS, M ratio 1:2) could interact with CLA through H-bonding and a hydrogen-bonded ion pair. The CHEMS was found necessary to maintain the stability of CLE.Ultracentrifugation showed that almost 88% CLA could be loaded into the interfacial layer.The optimized CLE formulation could withstand autoclaving at 121 °C for 10 min and remain stable after three freeze–thaw cycles. The in vitro susceptibility test revealed that the CLA–CHEMS ion-pair and CLE have similar activity to the parent drug against many different bacterial strains. The in vivo antibacterial activity showed that the ED50 of intravenous CLE was markedly lower than that of CLA solution administrated orally. CLE exhibited pronounced antibacterial activity and might be a candidate for a new nanocarrier for CLA with potential advantages over the current commercial formulation. | Haoyu Gong Sicong Geng Qi Zheng Puxiu Wang Lifeng Luo Xiuzhi Wang Yan Zhang Yu Zhang Haibing He Xing Tang | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，5： | 1 |
| 6 | Adhesion to fibronectin induces p27 Kip1 nuclear accumulation through down-regulation of Jab1 and contributes to cell adhesion-mediated drug resistance (CAM-DR) in RPMI 8,226 cells显示文摘 | Min Fei Qinglei Hang Sicong Hou Songbin He Changgeng Ruan | 2014 | Molecular and Cellular Biochemistry2014，，1： | 1 |
| 7 | Bioinspired Anti-Icing Hydrogel Enabled by Ice-Nucleating Protein显示文摘Ice-nucleating proteins(INPs)are the most effective ice-nucleating agents that play a significant role in preventing freeze injuries in freeze-tolerant organisms.INPs promote ice nucleation in the extracellular space,harvesting water from cells due to the low vapor pressure of ice compared with water,thereby protecting freeze-tolerant organisms from intracellular freezing.The antifreeze mechanism of INPs offers a unique opportunity to inhibit large-scale freezing by localized control of ice formation,with valuable enlightenment in anti-icing material sciences.By learning from nature,we transferred the excellent ice nucleation-facilitating capability of INPs along with an antifreeze concept of spatially controlled ice nucleation to anti-icing material design,fabricating icephobic coatings that consisted of patterned hydrogel-encapsulated INP(PHINP).The ice patterns were templated by patterned PHINPs via the tuning of ice nucleation so that the ice coverage fraction could be controlled by<30%on almost all PHINP-coated surfaces.Combining PHINP with solar-thermal conversion surfaces endowed the composite coatings with high anti-icing performances at any time of the day. | Zhanhui Wang Baixue Lin Siyu Sheng Sicong Tan Pengchao Wang Yong Tao Zhang Liu Zhiyuan He Jianjun Wang | 2022 | CCS Chemistry2022，4，1： | 0 |
| 8 | The in vivo targeted molecular imaging of fluorescent silicon nanoparticles in Caenorhabditis elegans显示文摘 | Yanfeng Zhou Yun Zhang Yiling Zhong Rong Fu Sicong Wu Qin Wang Houyu Wang Yuanyuan Su Huimin Zhang Yao He | 2018 | Nano Research2018，11，5： | 0 |
| 9 | When and How to Adjust Non-Pharmacological Interventions Concurrent with Booster Vaccinations Against COVID-19—Guangdong,China,2022显示文摘Introduction:With the large-scale roll-out of the coronavirus disease 2019(COVID-19)booster vaccination effort(a vaccine dose given 6 months after completing primary vaccination)in China,we explore when and how China could lift non-pharmacological interventions(NPIs)against COVID-19 in 2022.Methods:Using a modified susceptible-infectiousrecovered(SIR)mathematical model,we projected the COVID-19 epidemic situation and required medical resources in Guangdong Province,China.Results:If the number of people entering from overseas recovers to 20%of the number in 2019,the epidemic in 2022 could be controlled at a low level by a containment(215 local cases)or suppression strategy(1,397 local cases).A mitigation strategy would lead to 21,722 local cases.A coexistence strategy would lead to a large epidemic with 6,850,083 local cases that would overwhelm Guangdong’s medical system.With 50%or 100%recovery of the 2019 level of travelers from overseas,the epidemic could also be controlled with containment or suppression,but enormous resources,including more hotel rooms for border quarantine,will be required.However,coexistence would lead to an uncontrollable epidemic with 12,922,032 local cases.Discussion:With booster vaccinations,the number of travelers from overseas could increase slightly in 2022,but a suppression strategy would need to be maintained to ensure a controllable epidemic. | Guanhao He Fangfang Zeng Jianpeng Xiao Jianguo Zhao Tao Liu Jianxiong Hu Sicong Zhang Ziqiang Lin Huaiping Zhu Dan Liu Min Kang Haojie Zhong Yan Li Limei Sun Yuwei Yang Zhixing Li Zuhua Rong Weilin Zeng Xing Li Zhihua Zhu Xiaofeng Liang Wenjun Ma | 2022 | China CDC weekly2022，4，10： | 0 |
| 10 | Interfacial electronic interaction enabling exposed Pt(110)facets with high specific activity in hydrogen evolution reaction显示文摘To achieve a complete industrial chain of hydrogen energy,the development of efficient electrocatalysts for hydrogen evolution reaction(HER)is of great concerns.Herein,a nickel nitride supported platinum(Pt)catalyst with highly exposed Pt(110)facets(Pt_((110))-Ni_(3)N)is obtained for catalyzing HER.Combined X-ray spectra and density functional theory studies demonstrate that the interfacial electronic interaction between Pt and Ni3N support can promote the hydrogen evolution on Pt(110)facets by weakening hydrogen adsorption.As a result,the Pt_((110))-Ni_(3)N catalyst delivers an obviously higher specific activity than commercial 20 wt.%Pt/C in acidic media.This work suggests that the suitable interface modulation may play a vital role in rationally designing advanced electrocatalysts. | Sicong Qiao Qun He Quan Zhou Yuzhu Zhou Wenjie Xu Hongwei Shou Yuyang Cao Shuangming Chen Xiaojun Wu Li Song | 2023 | Nano Research2023，16，1： | 0 |
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