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| 1 | Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells显示文摘 | Ma Y Xu Y Xiao Z Yang W Zhang C Song E Du Y Li L | 2006 | 中国生物学文摘2006，20，5： | 58 |
| 2 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 3 | An epigenomic approach to therapy for tamoxifen-resistant breast cancer显示文摘Tamoxifen 是为雌激素受体 alpha 的前线治疗(ERα) 在绝经前的女人的积极的胸肿瘤。然而,到 tamoxifen 的抵抗发生在许多病人。嗯仍然与获得的 tamoxifen 抵抗在乳癌房间的生长起一个关键作用,建议那 ERα为治疗仍然是一个有效目标 tamoxifen 抵抗(Tam-R ) 乳癌。以识别 ERα 的新奇管理者;发信号,通过对 histone 甲基修饰词的一幅小规模的 siRNA 屏幕,我们发现了 WHSC1, histone H3K36 methyltransferase, ERα 的一个积极管理者;在乳癌房间发信号。我们证明 WHSC1 被招募到 ERα由 BET 蛋白质 BRD3/4 的基因,并且便于 ERα基因表示。小分子的赌注蛋白质禁止者 JQ1 potently 压制了经典 ERα发信号的小径和在文化的 Tam-R 乳癌房间的生长。用一个 Tam-R 乳癌异种皮移植老鼠模型,我们与 JQ1 和 ER degrader fulvestrant 由 JQ1 和联合治疗的强壮的长持续的效果在 vivo 反胸癌症活动示威了。一起拿,我们提供 epigenomic 蛋白质 BRD3/4 和 WHSC1 是雌激素受体发信号的必要管理者并且是为 Tam-R 乳癌的治疗的新奇治疗学的目标的证据。 | Qin Feng Zheng Zhang Martin J Shea Chad J Creighton Cristian Coarfa Susan G Hilsenbeck Rainer Lanz Bin He Lei Wang Xiaoyong Fu Agostina Nardone Yongcheng Song James Bradner Nicholas Mitsiades Constantine S Mitsiades C Kent Osborne Rachel Schiff Bert W O'Malley | 2014 | Cell Research2014，24，7： | 10 |
| 4 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005，26，8： | 6 |
| 5 | Uterine biology in pigs and sheep显示文摘There is a dialogue between the developing conceptus (embryo-fetus and associated placental membranes) and maternal uterus which must be established during the peri-implantation period for pregnancy recognition signaling, implantation, regulation of gene expression by uterine epithelial and stromal cells, placentation and exchange of nutrients and gases. The uterus provide a microenvironment in which molecules secreted by uterine epithelia or transported into the uterine lumen represent histotroph required for growth and development of the conceptus and receptivity of the uterus to implantation. Pregnancy recognition signaling mechanisms sustain the functional lifespan of the corpora lutea (CL) which produce progesterone, the hormone of pregnancy essential for uterine functions that support implantation and placentation required for a successful outcome of pregnancy. It is within the peri-implantation period that most embryonic deaths occur due to deficiencies attributed to uterine functions or failure of the conceptus to develop appropriately, signal pregnancy recognition and/or undergo implantation and placentation. With proper placentation, the fetal fluids and fetal membranes each have unique functions to ensure hematotrophic and histotrophic nutrition in support of growth and development of the fetus. The endocrine status of the pregnant female and her nutritional status are critical for successful establishment and maintenance of pregnancy. This review addresses the complexity of key mechanisms that are characteristic of successful reproduction in sheep and pigs and gaps in knowledge that must be the subject of research in order to enhance fertility and reproductive health of livestock species. | Fuller W Bazer Gwonhwa Song Jinyoung Kim Kathrin A Dunlap Michael Carey Satterfield Gregory A Johnson Robert C Burghardt Guoyao Wu | 2012 | Journal of Animal Science and Biotechnology2012，3，3： | 3 |
| 6 | Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population 显示文摘 | Song C Xing D Tan W | 2001 | Cancer Res2001，61，： | 2 |
| 7 | The effect of talc on cell nucleation in extrusion foam processing of polypropylene with CO2 and isopentane显示文摘 | Park C B Cheung L K Song S W | 1998 | Cellular Polymers1998，17，4： | 2 |
| 8 | Growth of Benzil Crystals by Vertical Dynamic Gradient Freeze Technique in a Transparent Furnace显示文摘 | Lan C W Song C R | 1997 | Journal of Crystal Growth1997，180，： | 2 |
| 9 | Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture显示文摘 | Pan W Quarles LD Song LH Yu YH Jiao C Tang HB Jiang CH Deng HW Li YJ Zhou HH Xiao ZS | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 10 | Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells 显示文摘 | Ma YL Xu YS Xiao ZF Yang W Zhang C Song E | 2005 | Stem Cells2005，24，2： | 1 |
| 11 | YAG laser percussion drilling of a functional multi-layer thin plate 显示文摘 | WANG A H WANG W Y BAI Z K XIE C S ZENG D W SONG W L | 2007 | Optics & Laser Technology2007，39，： | 1 |
| 12 | Induction of protective immunity in chickens vaccinated with infectious bronchitis virus S1 glycoprotein expressed by a recombinant baculovirus显示文摘 | Song C S Lee Y J Lee C W | 1998 | J Gen Virol1998，79，： | 1 |
| 13 | A FAFFA-MLFMA algorithm for electromagnetic scattering 显示文摘 | Chew W C Cui T J Song J M | 2002 | IEEE Trans Antennas and Propagat2002，50，11： | 1 |
| 14 | Local Fe structure and ferromagnetism in Fe - doped ZnO films 显示文摘 | Wei X X Song C Geng K W | 2006 | J Phys : Condens Matter2006，18，： | 1 |
| 15 | Anglnex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells显示文摘 | Dings R P Williams B W Song C W | 2005 | Int J Cancer2005，115，2： | 1 |
| 16 | Fast multipole method solution of three dimensional integral equation显示文摘 | Song J M Chew W C | 1995 | IEEE Transae tions on Antennas Propagation1995，45，10： | 1 |
| 17 | 10 million unknowns:Is it that big显示文摘 | S Velamparambil W C Chew J Song | 2003 | IEEE Antennas Propagat Mag2003，45，2： | 1 |
| 18 | Hydrophobic organic chemicals (HOCs) removal from biologically treated landfill leachate by powder-activated carbon ( PAC ), granular-activated carbon ( GAC ) and biornimetic fat cell (BFC)显示文摘 | Song L Y Zhao Y C Sun W M | 2009 | Journal of Hazardous Materials2009，163，23： | 1 |
| 19 | Novel role for cystic fibrosis transmembrane conductance regulator in alveolar fluid clearance in lipopolysaccharide-induced acute lung injury in mice显示文摘 | Jin W Song Y Bai C | 2013 | Respirology2013，18，6： | 1 |
| 20 | Small-signal model-based control strategy for balancing individual DC capacitor voltages in cascaded multilevel inverterbased STATCOM显示文摘 | Liu Y Huang A Q Song W C | | 0，，06： | 1 |
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