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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 3 | Targeting key alteration minerals in epithermal deposits in Patagonia,Argentina,using ASTER imagery and principal component analysis显示文摘 | Crosta A P Souza C R Azevedo F | 2003 | International Journal of Remote Sensing2003，24，21： | 1 |
| 4 | Synthesis of tungsten carbide through gas-solid reaction at low temperatures 显示文摘 | Medeiros F F P De Oliveira S A De Souza C P | 2001 | Materials Science and Engineering2001，315，： | 1 |
| 5 | Two-phase n-butenes dimerization by nickel complexes in molten salt media显示文摘 | Dupont J de Souza R F | 1998 | Appl Catal A:General1998，775，： | 1 |
| 6 | 显示文摘 | de Oliveira M F May J E | 2000 | J Non-Cryst Solids2000，，273： | 1 |
| 7 | Comparison of reverse transcriptase PCR, reverse transcriptase loop-mediated isothermal amplification, and culture-based assays for Salmonella detection from pork processing environments显示文摘 | Techathuvanan C Draughon F A D'Souza D H | 2011 | J Food Prot2011，74，： | 1 |
| 8 | Uncertain estimate in resources assessment: A geostatistical contribution 显示文摘 | Souza L E Costa J F C L Koppe J C | 2004 | Natural Resources Research2004，13，1： | 1 |
| 9 | Expression of the bovine papillomavirus type 1, 2 and 4 L1 genes in the yeast Pichia pastoris显示文摘 | Jesus A L Mariz F C Souza H M | 2012 | Genet Mol Res2012，11，3： | 1 |
| 10 | Effect of soil moisture and fertilization on Perola pineapple in Coastal Tableland areas of Brazil 显示文摘 | Souza L F D de Almeida O A Caldas R C | 2002 | Tropical Agriculture2002，79，2： | 1 |
| 11 | The σ phase formation in annealed UNS S31803 duplex stainless steel: Texture aspects显示文摘 | Souza C M Abreu H F G Tavares S S M | 2008 | Materials Characterization2008，59，9： | 1 |
| 12 | Targeting key alteration minerals in epithermal deposits in Patagonia,Argentina,using ASTER imagery and principal component analysis显示文摘 | Crosta A P Souza Filho C R Azevedo F Brodie C | | 0，，21： | 1 |
| 13 | Measles antibody prevalence after mass immunization in Sao Paulo, Brazi显示文摘 | Moraes J C Souza V A U F | 1991 | Bull WHO1991，69，5： | 1 |
| 14 | Antioxidant ac- tivity and total phenolic content of Agaricus brasiliensis ( Agari- cus blazei Murril) in two stages of maturity 显示文摘 | Soares A A Souza C G M Daniel F M | 2009 | Food Chemis- try2009，112，4： | 1 |
| 15 | Quality of life and measure of Disease in elderly people with end-stage renal disease显示文摘 | Souza F F Cintra F A Gallani M C | 2005 | Rev Bras Enferm2005，58，5： | 1 |
| 16 | Input and output quantized feedback linear systems显示文摘 | Coutinho D F Fu M Y De Souza C E | | 0，，03： | 1 |
| 17 | Safety and efficacy of bivalirudin monotherapy in patients with non-ST segment elevation myocardial infarction undergoing PCI: results from the ACUITY study显示文摘 | Souza C F Mehran R Kirtane A J | 2013 | J Am Coll Cardiol2013，62，1851： | 1 |
| 18 | Powder properties and system behavior during spray drying of Bauhinia fomicata link extract显示文摘 | Souza C R F Oliveira W P | 2006 | Drying Technology2006，24，46： | 1 |
| 19 | Shot noise in a spin - diode geometry 显示文摘 | SOUZA F M NERO J D EGUES J C | 2010 | J Supercond Nov Magn2010，23，1： | 1 |
| 20 | Depositional and diagenetic controls on the reservoir quality of Lower Creta- ceous Pendeneia sandstones, Potiguar rift basin, Brazil显示文摘 | dos Anjos S M C de Ros L F de Souza R S | 2000 | AAPG Bulletin2000，84，11： | 1 |
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