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    题名 作者 年代 出处 被引量
1Diabetes--Role of epigenetics,genetics,and physiological factors显示文摘Cells of organ systems are endowed with a relatively similar genome while epigenome niches keep varying chronologically and defined explicitly in the respective tissues.The genome of an individual is always influenced by parental,embryonic,tissue-specific,and environmental epigenomes and the same must have been the possible reason for invariable inquiries relating to familial,environmental and life style patterns in the preliminary investigations of diabetic complications.Unprecedented methylation of lysine residues of histones and cytosines of CpG islands of promoter DNA impede the transcription of genes and homocysteine is the metabolic key player of methyl groups.Gck and COX7A1 are the 2 examples in the present review to elucidate the epigenetic influence on the onset of diabetes.miRNAs are additional promising cellular components influencing both at transcriptional and translational levels and promoting either in favour or against(i.e.,feed back) TFs,signaling factors and proteins through their pliotropic effects and thus are reported to regulate cellular physiology.miR-124a and miR-9 are primarily endemic to nervous tissue and they are now being exploited in islets for their function in executing exocytosis of insulin,which of course is one of the fundamental canons of diabetes.miR-375 persuades beta cells for glucose-induced insulin gene expression.The current approach to evaluate the constellation of genes and their products involved in diabetes in huge number of samples through GWA studies may unravel intricacies involved in the management of diabetes and its associated consequences.Sreerama Krupanidhi Saikiran K. Sedimbi Ganesan Vaishnav Sreerama Sai Madhukar Carani B. Sanjeevi 2009中南大学学报(医学版)2009,34,9:3
2Regulation of urokinase receptor mRNA stability by hnRNP C in lung epithelial cells显示文摘Sreerama Shetty 2005Molecular and Cellular Biochemistry (-)2005,,1:1
3Antigenic determinants and reactive sites of a trypsin/chymotrypsin double-headed inhibitor from horse gram(Dolichos biflorus)显示文摘Sreerama YN Gowda LR 1997Biochim Biophys Acta1997,1343,:1
4Impact of processing on the phenolic profiles of small millets: evaluation of their antioxidant and enzyme inhibitory properties associated with hyperglycemia显示文摘PRADEEP P M SREERAMA Y N 2014Food Chemistry2014,116,:1
5Estimation of the number of ct - helical and β - strand segments in pro- teins using circular dichroism spectroscopy 显示文摘Sreerama N Venyaminov S Y U Woody R W 1999Protein Sci- ence1999,8,2:1
6Computation and analysis of protein Circular Dichroism spectra显示文摘Sreerama N Woody R W 0,,:1
7Maehinability of C45 steel with deep cryogenic treated tungsten carbide cutting tool inserts显示文摘Sreerama Reddy T V Sornakumar T Venkatarama Reddy M 2009Refractory Metals and Hard Materials2009,27,1:1
8Estimation of protein secondary structure from circular dichroism spectra:comparison of CONTIN, SELCON,and CDSSTR methods with an expanded reference set 显示文摘Sreerama N Woody R W 2000Anal Biochem2000,287,:1
9Estimation of protein secondary structure from circular dichroism spectra: Comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set 显示文摘Sreerama N Woody R W 2000Analytical Biochemistry2000,287,2:1
10Phenolic Antioxidants in Some Vigna Species of Legumes and their Distinct Inhibitory Effects on ct-Glucosidase and Pancreatic Lipase Activities显示文摘Sreerama Y N Takahashi Y Yamaki K 2012Journal of food science2012,77,9:1
11Composition and enzyme inhibitory properties of finger millet (Eleusine coracana L.) seed coat phenolics: Mode of inhibition of α-glucosidase and pancreatic amylase显示文摘S. Shobana Y.N. Sreerama N.G. Malleshi 2009Food Chemistry2009,,4:1
12Poly (Pro) II helixes in globularproteins: identification and circular dichroic analysis显示文摘SREERAMA N WOODY R W 1994Biochemistry1994,33,10:1
13An artificial neural network based dynamic controller for a robot in a multi-agent system 显示文摘Jolly K G Sreerama K R Vijayakumar R 2009Neurocomputing2009,73,123:1
14显示文摘Sreerama N Woody R W 2004Methods Enzymol2004,383,:1
15Nutritional implications and flour functionality of popped/expanded horse gram显示文摘SREERAMA TN SASIKALA VB PRATAPE VM 0,,03:1
16Determination of reduced order model for torsional interaction investigations using selective modal analysis-part II:Application to practical power systems显示文摘Vinod Pottakulatha Elizabeth P Cheriyana R Sreerama Kumarb 2013International Journal of Electrical Power & Energy Systems2013,44,1:1
17Estimation of protein secondary structure from CD spectra:Inclusion of denatured proteins with native proteins in the analysis显示文摘SREERAMA N VENYAMINOV S Y WOODY R W 2000Anal Biochem2000,287,2:1
18Nuclear oxidation in flavone series part XI, A new synthesis of nobiletin 显示文摘Sreerama M V V Seshadri T R 1948Proeeedings Mathematical Sciences1948,27,3:1
19Poly(Pro)II helices in globular proteins :Identification and circular dichroic analysis显示文摘SREERAMA N WOODY R W 1994Biochem- istry1994,33,10:1
20Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set显示文摘Sreerama N Woody R W 2000Analytical biochemistry2000,287,2:1
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