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1Preoperative sorting of circulating T lymphocytes in patients with esophageal squamous cell carcinoma: Its prognostic significance显示文摘AIM: To elucidate the immunologic parameters for the outcome of patients with malignant tumors, especially esophageal squamous cell carcinoma (ESCC) associated with high malignant potential. METHODS: Clinicopathologic features were compared between patients with lower and higher CD4 and CD8 values as well as CD4/CD8 ratio in peripheral blood. RESULTS: The survival rate of patients with higher CD4 value was significantly better than that in patients with lower CD4 value (P = 0.039). The survival rate of patients with higher CD8 value was significantly worse than that of patients with lower CD8 value (P = 0.026). Similarly, the survival rate of patients with higher CD4/ CD8 ratio was significantly better than that of patients with lower CD4/CD8 ratio (P = 0.042). Additionally, multivariate analysis demonstrated that lower CD8 and lower CD4/CD8 ratio were factors independently associated with worse prognosis of patients. CONCLUSION: All the immunologic parameters can predict the outcome of patients with ESCC.Tadahiro Nozoe Yoshihiko Maehara Keizo Sugimachi 2005World Journal of Gastroenterology2005,11,42:18
2An unusual enteropathy-associated T-cell lymphoma with MYC translocation arising in a Japanese patient:A case report显示文摘Enteropathy-associated T-cell lymphoma(EATL) is a rare peripheral T-cell lymphoma classified into 2 types,with or without celiac disease,based on histology.Type 2 EATL is less commonly associated with celiac disease,in which cells are characterized by being monomorphic and small-to medium-sized.Cells are characterized by CD8 and CD56 expression and c-MYC oncogene locus gain.We present an atypical case of type 2 EATL in the jejunum,with human T-lymphotropic virus-1 that was CD4-CD8+ CD56-CD30-CD25-TIA-1+ and granzyme B+ on immunohistological staining.It also displayed translocation of chromosome 8p24(c-MYC),as determined by fluorescent in situ hybridization.Mucosal spreading and intraepithelial invasion by lymphoma with villous atrophy were detected adjacent to the mucosal layer.The lymphoma may be derived from intraepithelial CD8+ T cells,similar to celiac disease.Kenji Okumura Masahiko Ikebe Tatsuro Shimokama Morishige Takeshita Nao Kinjo Keishi Sugimachi Hidefumi Higashi 2012World Journal of Gastroenterology2012,18,19:3
3Predictors of Extrahepatic Recurrence After Curative Hepatectomy for Hepatocellular Carcinoma显示文摘Akinobu Taketomi Takeo Toshima Dai Kitagawa Takashi Motomura Kazuki Takeishi Yohei Mano Hiroto Kayashima Keishi Sugimachi Shinichi Aishima Yoichi Yamashita Toru Ikegami Tomonobu Gion Hideaki Uchiyama Yuji Soejima Takashi Maeda Ken Shirabe Yoshihiko Maehar 2010Annals of Surgical Oncology2010,,10:2
4Clinical significance of the expression of long non-coding RNA HOTAIRin primary hepatocellular carcinoma显示文摘Masahisa Ishibashi Ryunosuke Kogo Kohei Shibata Genta Sawada Yusuke Takahashi Junji Kurashige Sayuri Akiyoshi Shin Sasaki Takeshi Iwaya Tomoya Sudo Keishi Sugimachi Koshi Mimori Go Wakabayashi Masaki Mori 2013Oncology Reports2013,,3:2
5Clinical significance of vascular endothelial growth factor‐C (VEGF‐C) in breast cancer显示文摘Junko Kinoshita Kaoru Kitamura Akira Kabashima Hiroshi Saeki Shinji Tanaka Keizo Sugimachi 2001Breast Cancer Research and Treatment2001,,2:2
6One‐step venous reconstruction for a right lobe graft with multiple venous orifices in living donor liver transplantation显示文摘Yuji Soejima Naoyuki Ueda Takasuke Fukuhara Tomoharu Yoshizumi Toru Ikegami Yoichi Yamashita Keishi Sugimachi Akinobu Taketomi Yoshihiko Maehara 2008Liver Transpl2008,,5:2
7Hepatocyte growth factor and transforming growth factor β1 contribute to regeneration of small-for-size liver graft immediately after transplantation显示文摘Mizuki Ninomiya Noboru Harada Satoko Shiotani Shoji Hiroshige Ryosuke Minagawa Yuji Soejima Taketoshi Suehiro Takashi Nishizaki Mitsuo Shimada Keizo Sugimachi 2003Transplant International2003,,11:2
8A Simple Hilar Dissection Technique Preserving Maximum Blood Supply to the Bile Duct in Living Donor Liver Transplantation显示文摘Yuji Soejima Takasuke Fukuhara Kazutoyo Morita Tomoharu Yoshizumi Toru Ikegami Yoichi Yamashita Keishi Sugimachi Akinobu Taketomi Yoshihiko Maehara 2008Transplantation2008,,10:2
9Zero mortality in more than 300 hepatic resections: validity of preoperative volumetric analysis显示文摘Shinji Itoh Ken Shirabe Akinobu Taketomi Kazutoyo Morita Norifumi Harimoto Eiji Tsujita Keishi Sugimachi Yo-ichi Yamashita Tomonobu Gion Yoshihiko Maehara 2012Surgery Today2012,,5:2
10Robot-assisted gastric surgery显示文摘Makoto Hashizume Keizo Sugimachi 2003Surgical Clinics of North America2003,,6:2
11Expression and antitumor effects of TRAIL in human cholangiocarcinoma显示文摘Tanaka S Sugimachi K Shirabe K 2000Hcpatology2000,32,3:1
12Biological role of phosphatase PTEN in cancer and tissue injury healing显示文摘Tsugawa K Jones MK Sugimachi K 2002Front Biosci2002,7,1:1
13Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma显示文摘Tanaka S Sugimachi K Yamashita Yi Y 2002Hepatology2002,35,4:1
14Surgery for Gastric Cancer:10-year Experience Worldwide显示文摘Adachi Y Kitano S Sugimachi K 2001Gastric Cancer2001,4,4:1
15Preliminary report of tumor metastasis during liver regeneration after hepatic resection in rats显示文摘Yasuharu Ikeda Takashi Matsumata Kenji Takenaka Osamu Sasaki Kazuhiko Soejima Keizo Sugimachi 1995European Journal of Surgical Oncology1995,,2:1
16Laparosocpic hepatectomy:new approach for hepatocellular carcinoma显示文摘 Shimada M Sugimachi K 2000J Hepatobiliary PanereatSurg2000,7,3:1
17Angiopoietin switching regulates angiogenesis and progression of human hepatocellular carcinoma 显示文摘Sugimachi K Tanaka S Taguchi K 2003J Clin Pathol2003,56,11:1
18Early experiences of endoscopic procedures in general surgery assisted by a computer-enhanced surgical system显示文摘M. Hashizume M. Shimada M. Tomikawa Y. Ikeda I. Takahashi R. Abe F. Koga N. Gotoh K. Konishi S. Maehara K. Sugimachi 2002Surgical Endoscopy2002,,8:1
19Relationship between biologic behavior and phenotypic expression in intramucosal gastric carcinomas显示文摘Kabashima A Yao T sugimachi K Tsuneyoshi M 2002Hum Pathol2002,33,1:1
20Surgery for gastric cancer:10-year experience worldwide显示文摘Adachi Y Kitano S Sugimachi K 2001Gastric Cancer2001,4,4:1
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