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| 1 | Surface Integrity of Ultrasonically-Assisted Milled Ti6Al4V Alloy Manufactured by Selective Laser Melting显示文摘The Ti6Al4V parts produced by the existing selective laser melting(SLM)are mainly confronted with poor surface finish and inevitable interior defects,which substantially deteriorates the mechanical properties and performances of the parts.In this regard,ultrasonically-assisted machining(UAM)technique is commonly introduced to improve the machining quality due to its merits in increasing tool life and reducing cutting force.However,most of the previous studies focus on the performance of UAM with ultrasonic vibrations applied in the tangential and feed directions,whereas few of them on the impact of ultrasonic vibration along the vertical direction.In this study,the effects of feed rate on surface integrity in ultrasonically-assisted vertical milling(UAVM)of the Ti6Al4V alloy manufactured by SLM were systemically investigated compared with the conventional machining(CM)method.The results revealed that the milling forces in UAVM showed a lower amplitude than that in CM due to the intermittent cutting style.The surface roughness values of the parts produced by UAVM were generally greater than that by CM owing to the extra sinusoidal vibration textures induced by the milling cutter.Moreover,the extra vertical ultrasonic vibration in UAVM was beneficial to suppressing machining chatter.As feed rate increased,surface microhardness and thickness of the plastic deformation zone in CM raised due to more intensive plastic deformation,while these two material properties in UAVM were reduced owing to the mitigated impact effect by the high-frequency vibration of the milling cutter.Therefore,the improved surface microhardness and reduced thickness of the subsurface deformation layer in UAVM were ascribed to the vertical high-frequency impact of the milling cutter in UAVM.In general,the results of this study provided an in-depth understanding in UAVM of Ti6Al4V parts manufactured by SLM. | Sai Guo Wei Du Qinghong Jiang Zhigang Dong Bi Zhang | 2021 | Chinese Journal of Mechanical Engineering2021，34，4： | 2 |
| 2 | Sampling-Based Approximate Skyline Query in Sensor Equipped IoT Networks显示文摘Mobile-edge computing casts the computation-intensive and delay-sensitive applications of mobile devices onto network edges.Task offloading incurs extra communication latency and energy cost,and extensive efforts have focused on offloading schemes.Many metrics of the system utility are defined to achieve satisfactory quality of experience.However,most existing works overlook the balance between throughput and fairness.This study investigates the problem of finding an optimal offloading scheme in which the objective of optimization aims to maximize the system utility for leveraging between throughput and fairness.Based on Karush-Kuhn-Tucker condition,the expectation of time complexity is analyzed to derive the optimal scheme.A gradient-based approach for utility-aware task offloading is given.Furthermore,we provide an increment-based greedy approximation algorithm with 1+1/(e-1)ratio.Experimental results show that the proposed algorithms can achieve effective performance in utility and accuracy. | Ran Bi Akshita Maradapu Vera Venkata Sai Xiuzhen Cheng Wei Cheng Zhi Tian Yingshu Li | 2021 | Tsinghua Science and Technology2021，26，2： | 2 |
| 3 | An ionic liquid-modified graphene based molecular imprinting electrochemical sensor for sensitive detection of bovine hemoglobin显示文摘 | Zonghua Wang Feng Li Jianfei Xia Lin Xia Feifei Zhang Sai Bi Guoyu Shi Yanzhi Xia Jingquan Liu Yanhui Li Linhua Xia | 2014 | Biosensors and Bioelectronics2014，，： | 1 |
| 4 | Synergistic in-situ growth of silver nanoparticles with nanozyme activity for dual-mode biosensing and cancer theranostics显示文摘A multifunctional nanocomposite of AgNPs@GQDs is prepared by synergistic in-situ growth of silver nanoparticles(AgNPs)on the complex of tannic acid(TA)and graphene quantum dots(GQDs)for the construction of dual-mode biosensing platform and cancer theranostics.The nanocomposite exhibits a hydrogen peroxide(H_(2)O_(2))-responsive degradation,in which Ag^(0)is oxidized to Ag^(+)along with the release of oxidized TA and GQDs.The degradation induces the decreased absorbance and enhanced fluorescence(FL)intensity due to the suppression of Forster resonance ene rgy transfer(FRET)in AgNPs@GQDs,which is employed for colorimetric/fluorescence dual-mode sensing of H_(2)O_(2).The intrinsic peroxidase-like activity of GQDs nanozyme can effectively catalyze the oxidation reaction,enhancing the detection sensitivity significantly.Based on the generation of H_(2)O_(2)from the oxidation of glucose with the catalysis of glucose oxidase(GOx),this nanoprobe is versatilely used for the determination of glucose in human serum.Further,through combining the H_(2)O_(2)-responsive degradation of AgNPs@GQDs with high H_(2)O_(2)level in cancer cells,the nanocomposites exhibit good performance in cancer cell recognition and therapy,in which the synergistic anticancer effect of Ag^(+)and oxidized TA contribute to effective cell death,and the liberated GQDs are used to monitor the therapeutic effect by cell imaging. | Xin Hai Yuwei Li Kaixin Yu Shuzhen Yue Yuanfang Li Weiling Song Sai Bi Xueji Zhang | 2021 | Chinese Chemical Letters2021，32，3： | 1 |
| 5 | Gold Nanolabels for New Enhanced Chemiluminescence Immunoassay of Alpha-Fetoprotein Based on Magnetic Beads显示文摘 | Sai Bi Yameng Yan Xiaoyan Yang | | 0，，： | 1 |
| 6 | GiT-based structural geologic feature analysis of the southern segment of Longmenshan fault zone for earthquake evidence显示文摘The Longmenshan fault is a thrust fault which runs along the base of the Longmen Mountains in Sichuan province,southwestern China.The southern segment of the fault had two distinct responses to the Ms 8 Wenchuan and Ms 7 Lushan earthquakes.This study determines characteristics of the structural geology of the Longmenshan fault to evaluate how it influenced the two aforementioned earthquakes.This research was done within a Geoinformation Technologies(Gi T) environment based on multi-source remote sensing and crustal movement data extracted from the Global Positioning System(GPS).The spatial distribution of the southern segment of the Longmenshan fault zone was comprehensively analyzed to study both earthquakes.The study revealed that the Wenchuanand Lushan earthquakes occurred on two relatively independent faults.In addition,there was a nearly constant-velocity crustal movement zone between the two epicenters that probably had a compressive stress with slow motion.Furthermore,the central fault and a mountain back fault gradually merged from north to south.The Lushan earthquake was not an aftershock of the Wenchuan earthquake.The research showed that fault zones within 30–50 km of State Highway 318 are intensive and complex.In addition,crustal movement velocity decreased rapidly,with a strong multi-directional shear zone.Thus,activity in that zone was likely stronger than in the northern part over the medium to long term. | YE Cheng-ming CUI Peng Saied PIRASTEH Jonathan LI MENG Qingkai BI Xiao-jia ZHANG Jian-qiang | 2016 | Journal of Mountain Science2016，13，5： | 1 |
| 7 | Dihydroartemisinin increases temozolomide efficacy in glioma cells byinducing autophagy显示文摘 | Ze?Shun Zhang Jing Wang You?Bi Shen Cheng?Cheng Guo Ke Sai Fu?Rong Chen Xin Mei Fu Han Zhong?Ping Chen | 2015 | Oncology Letters2015，，1： | 1 |
| 8 | Gold Nanolabels for New Enhanced Chemiluminescence Immunoassay o- fAlpha-Fetoprotein Based on Magnetic Beads 显示文摘 | Sai Bi Yameng Yan Xiaoyan Yang Shusheng Zhang | 2009 | Chem Eur J2009，15，： | 1 |
| 9 | Soil bacterial communities interact with silicon fraction transformation and promote rice yield after long-term straw return显示文摘Returning crop straw into the soil is an important practice to balance biogenic and bioavailable silicon(Si)pool in paddy,which is crucial for the healthy growth of rice.However,owing to little knowledge about soil microbial communities responsible for straw degradation,how straw return affects Si bioavailability,its uptake,and rice yield remains elusive.Herein,we investigate the change of soil Si fractions and microbial community in a 39-year-old paddy field amended by a long-term straw return.Results show that rice straw return significantly increased soil bioavailable Si and rice yield from 29.9%to 61.6%and from 14.5%to 23.6%,respectively,when compared to NPK fertilization alone.Straw return significantly altered soil microbial community abundance.Acidobacteria was positively and significantly related to amorphous Si,while Rokubacteria at phylum level,Deltaproteobacteria,and Holophagae at class level was negatively and significantly related to organic matter adsorbed and Fe/Mn-oxide-combined Si in soils.Redundancy analysis of their correlations further demonstrated that Si status significantly explained 12%of soil bacterial community variation.These findings suggest that soil bacteria community and diversity interact with Si mobility by altering its transformation,thus resulting in the balance of various nutrient sources to drive biological Si cycle in agroecosystem. | Alin Song Zimin Li Yulin Liao Yongchao Liang Enzhao Wang Sai Wang Xu Li Jingjing Bi Zhiyuan Si Yanhong Lu Jun Nie Fenliang Fan | 2021 | Soil Ecology Letters2021，3，4： | 0 |
| 10 | Aqueous-phase synthesis of upconversion metal-organic frameworks for ATP-responsive in situ imaging and targeted combinational cancer therapy显示文摘Herein,the nanoscaled ATP-responsive upconversion metal-organic frameworks(UCMOFs)are aqueousphase synthesized for co-delivery of therapeutic protein cytochrome c(Cyt c)and chemodrugs doxorubicin(DOX),achieving targeted combinational therapy of human cervical cancer.The UCMOFs are rationally fabricated by growing ZIF-90 on mesoporous silica-coated upconversion nanoparticles(UCNPs),in which the ZIF-90 layer attenuates the upconversion luminescence(UCL)and the rigid frameworks increase the stability of encapsulated proteins.Once the UCMOF@DOX/Cyt c are internalized into HeLa cells via specific recognition of sgc8 aptamers,the intracellular ATP triggers the dissolution of ZIF-90 into Zn^(2+),which facilitates not only the release of Cyt c and DOX but also the restoration of UCL for real-time monitoring of drug release.It has been demonstrated that the therapeutic efficacy is greatly improved by the combination of caspase-mediated apoptosis activated by Cyt c(protein therapeutics),DNA fragmentation induced by DOX(chemotherapy),and Zn;-promoted generation of reactive oxygen species(ROS)(oxidative stress).Overall,our proposed multifunctional UCMOFs provide an effective platform for targeted combinational cancer therapy and in situ imaging,which hold great promise in biomedical and clinical applications. | Lin Yang Shuaidong Zhu Zhimei He Xiangli Li Jiangning Chen Sai Bi Jun-Jie Zhu | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 11 | Correction to:DNA Nanotechnology for Multimodal Synergistic Theranostics显示文摘Correction to:Journal of Analysis and Testing http://gffzzd3cc09b8251d45dfsvwn95xv6wvpc60pn.ffgz.tsg.suse.edu.cn/10.1007/s41664-021-00182-z In the references of the original article,the item 118 should be deleted because it’s the same as 102.These should be revised as follows.The original article has been corrected. | Kai-Xin Yu Zhen-Jie Qiao Wei-Ling Song Sai Bi | 2021 | Journal of Analysis and Testing2021，5，4： | 0 |
| 12 | pH-Responsive Magnetic I-Motif Container Coupled with DNA Walker for Construction of Dual-Signal Electrochemical Biosensor显示文摘Herein,a dual-signal electrochemical biosensor has been developed by self-assembly of pH-activatable i-motif probes on magnetic microparticles(MMPs)coupled with DNA walker for signal amplification.In this study,the cytosine(C)-rich single-stranded DNAs are hybridized with DNA initiators to obtain the long-nicked duplexes with repeated units,which are further captured on MMPs to form the magnetic i-motif containers.The resulting duplexes contain abundant G-C base pairs,thus providing extensive binding sites for doxorubicin(DOX).At acidic pH,the C-rich sequences are folded into i-motif structure,resulting in the release of DOX and walker initiators.In this case,the liberated DOX is adsorbed on gra-phene quantum dots-modified glassy carbon electrode viaπ-πinteraction,while the walker initiators as a moving part can catalyze the hybridization between MB-modified fueler DNA and tracker DNA on electrode,contributing to the generation of dual electrochemical signals induced by MB and DOX.Importantly,the magnetic separation can effectively reduce the background,achieving sensitive biosensing of pH ranging from 4.0 to 7.4 with excellent stability.Moreover,the proposed dual-signal electrochemical biosensor has been successfully applied for accurate monitoring of pH in human serum,which holds great potential in pH-dependent bioassays,especially in ultra-micro analysis for clinical applications. | Xin-Yan Wang Yuanfang Li Shuzhen Lv Sai Bi | 2022 | Journal of Analysis and Testing2022，6，1： | 0 |
| 13 | Cortical branched actin determines cell cycle progression显示文摘The actin cytoskeleton generates and senses forces. Here we report that branched actin networks from the cell cortex depend on ARPC1B-containing Arp2/3 complexes and that they are specifically monitored by type I coronins to control cell cycle progression in mammary epithelial cells. Cortical ARPC1B-dependent branched actin networks are regulated by the RAC1/WAVE/ARPIN pathway and drive lamellipodial protrusions. Accordingly, we uncover that the duration of the G1 phase scales with migration persistence in single migrating cells. Moreover, cortical branched actin more generally determines S-phase entry by integrating soluble stimuli such as growth factors and mechanotransduction signals, ensuing from substratum rigidity or stretching of epithelial monolayers. Many tumour cells lose this dependence for cortical branched actin. But the RAC1-transformed tumour cells stop cycling upon Arp2/3 inhibition. Among all genes encoding Arp2/3 subunits, ARPC1B overexpression in tumours is associated with the poorest metastasis-free survival in breast cancer patients. Arp2/3 specificity may thus provide diagnostic and therapeutic opportunities in cancer. | Nicolas Molinie Svetlana N. Rubtsova Artem Fokin Sai P. Visweshwaran Nathalie Rocques Anna Polesskaya Anne Schnitzler Sophie Vacher Evgeny V. Denisov Lubov A. Tashireva Vladimir M. Perelmuter Nadezhda V. Cherdyntseva Ivan Bièche Alexis M. Gautreau | 2019 | Cell Research2019，29，6： | 0 |
| 14 | Surface Integrity of Inconel 738LC Parts Manufactured by Selective Laser Melting Followed by High-speed Milling显示文摘This study is concerned with the surface integrity of Inconel 738LC parts manufactured by selective laser melting(SLM)followed by high-speed milling(HSM).In the investigation process of surface integrity,the study employs ultradepth three-dimensional microscopy,laser scanning confocal microscopy,scanning electron microscopy,electron backscatter diffractometry,and energy dispersive spectroscopy to characterize the evolution of material microstructure,work hardening,residual stress coupling,and anisotropic effect of the building direction on surface integrity of the samples.The results show that SLM/HSM hybrid manufacturing can be an effective method to obtain better surface quality with a thinner machining metamorphic layer.High-speed machining is adopted to reduce cutting force and suppress machining heat,which is an effective way to produce better surface mechanical properties during the SLM/HSM hybrid manufacturing process.In general,high-speed milling of the SLM-built Inconel 738LC samples offers better surface integrity,compared to simplex additive manufacturing or casting. | Guanhui Ren Sai Guo Bi Zhang | 2023 | Chinese Journal of Mechanical Engineering2023，36，1： | 0 |
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