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| 1 | Darwin:a neuromorphic hardware co-processor based on Spiking Neural Networks显示文摘Broadly speaking, the goal of neuromorphic engineering is to build computer systems that mimic the brain. Spiking Neural Network(SNN) is a type of biologically-inspired neural networks that perform information processing based on discrete-time spikes, different from traditional Artificial Neural Network(ANN).Hardware implementation of SNNs is necessary for achieving high-performance and low-power. We present the Darwin Neural Processing Unit(NPU), a neuromorphic hardware co-processor based on SNN implemented with digitallogic, supporting a maximum of 2048 neurons, 20482= 4194304 synapses, and 15 possible synaptic delays.The Darwin NPU was fabricated by standard 180 nm CMOS technology with an area size of 5 × 5 mm2and70 MHz clock frequency at the worst case. It consumes 0.84 m W/MHz with 1.8 V power supply for typical applications. Two prototype applications are used to demonstrate the performance and efficiency of the hardware implementation. | Juncheng SHEN De MA Zonghua GU Ming ZHANG Xiaolei ZHU Xiaoqiang XU Qi XU Yangjing SHEN Gang PAN | 2016 | Science China(Information Sciences)2016，59，2： | 18 |
| 2 | H2A.Z Represses Gene Expression by Modulating Promoter Nucleosome Structure and Enhancer Histone Modifications in Arabidopsis显示文摘 | Xiaozhuan Dai Youhuang Bai Lihua Zhao Xianying DOU Yanhui Liu Lulu Wang Yi Li Weimin Li Yanan Hui Xinyu Huang Zonghua Wang Yuan Qin | 2017 | Molecular Plant2017，10，10： | 14 |
| 3 | Efficacy and safety of external application of Traditional Chinese Medicine for the treatment of acute gouty arthritis: a systematic review and Meta-analysis显示文摘OBJECTIVE:To evaluate the clinical efficacy and safety of external application of Traditional Chinese Medicine (EATCM) on acute gouty arthritis (AGA).METHODS:Six electronic data bases were retrieved from their inception to march 2017.15 randomized controlled clinical trials (RCTs) were included.The quality of the literatures was assessed according to Cochrane review criteria by using RevMan5.3 software;and related data was counted using Stata14.0 software.RESULTS:There was no significant difference in C-reactiveprotein (CRP) between experimental intervention group and control group [(WMD =1.093,95% C/(-2.514,4.701);P =0.553)].In terms of overall efficacy,the EATCM's treatment group was significantly superior to control group [(OR =3.692;95% CI (2.408,5.661);P <0.001)].The EATCM was better than western medicine treatments or other interventions in reducing the adverse reactions [(OR =0.135;95% CI (0.067,0.274);P < 0.001)].All these funnel plots showed unlikelihood of publishing bias.But due to excessive heterogeneity,the statistical results of serum uric acid and visual analogue scale and CRP between the two groups became uncertain.CONCLUSION:The results indicate that EATCM may have greater overall efficacy with fewer adverse drug reactions,although the evidence is weak owing to the low methodological quality and the small number of the included trials. | Huang Xinxing Zhu Zonghua Wu Guang-hui Min Peng Fei Peng Zhu Tao Wang Xuezong Xiao Lianbo | 2019 | Journal of Traditional Chinese Medicine2019，39，3： | 12 |
| 4 | Small RNA Profiling Reveals Phosphorus Deficiency as a Contributing Factor in Symptom Expression for Citrus Huanglongbing Disease显示文摘Huanglongbing (HLB ) 是与类 Candidatus Liberibacter 的细菌被联系的破坏柠檬疾病(Ca。L.) 。强大的诊断工具和管理策略被需要控制 HLB。小 RNA (sRNA ) 玩的主人在调整主人回答到病原体感染的一个重要角色并且为许多人的疾病被用作早诊断的标记,包括癌症。决定是否柠檬 sRNAs 调整主人回答到 HLB, sRNAs 从柠檬 sinensis 被介绍有 Ca 的 10 和 14 星期柱子 grafting。L。asiaticus (Las ) 积极或健康的织物。十新 microRNAs (miRNAs ) , 76 保存 miRNAs,和许多小介入 RNA (siRNAs ) 被发现。几 miRNAs 和 siRNAs 被 Las 感染高度导致,并且能潜在地被开发进 HLB 的早诊断标记。miR399,被磷饥饿在另外的植物种类导致,被与类似于 HLB 的症状引起柠檬 stubborna 疾病的 Las 然而并非 Spiroplasma citri 的感染明确地导致。我们与健康的树相比在 Las 积极的柠檬树上发现了磷的 35% 减小。HLB 积极的香甜的橘子树的适用的磷 oxyanion 答案减少了 HLB 症状严厉并且显著地在西南佛罗里达在 3 年的地试用期间改进了水果生产。我们的分子,生理,并且地数据建议那磷缺乏被连接到 HLB 疾病 symptomology。 | Hongwei Zhao Ruobai Sun Ute Albrecht Chellappan Padmanabhan Airong Wanga Michael D. Coffey Thomas Girke Zonghua Wang Timothy J. Close Mikeal Roose Raymond K. Yokomi Svetlana Folimonova Georgios Vidalakis Robert Rouse Kim D. Bowman Hailing Jin | 2013 | Molecular Plant2013，6，2： | 12 |
| 5 | Integrated removal of NO and mercury from coal combustion flue gas using manganese oxides supported on TiO_2显示文摘A catalyst composed of manganese oxides supported on titania(MnO_x/TiO_2) synthesized by a sol–gel method was selected to remove nitric oxide and mercury jointly at a relatively low temperature in simulated flue gas from coal-fired power plants. The physico-chemical characteristics of catalysts were investigated by X-ray fluorescence(XRF), X-ray diffraction(XRD), and X-ray photoelectron spectroscopy(XPS) analyses, etc. The effects of Mn loading,reaction temperature and individual flue gas components on denitration and Hg^0 removal were examined. The results indicated that the optimal Mn/Ti molar ratio was 0.8 and the best working temperature was 240°C for NO conversion. O_2 and a proper ratio of [NH_3]/[NO]are essential for the denitration reaction. Both NO conversion and Hg^0 removal efficiency could reach more than 80% when NO and Hg^0 were removed simultaneously using Mn0.8 Tiat 240°C.Hg^0 removal efficiency slightly declined as the Mn content increased in the catalysts. The reaction temperature had no significant effect on Hg^0 removal efficiency. O_2 and HCl had a promotional effect on Hg^0 removal. SO2 and NH_3were observed to weaken Hg^0 removal because of competitive adsorption. NO first facilitated Hg^0 removal and then had an inhibiting effect as NO concentration increased without O_2, and it exhibited weak inhibition of Hg^0 removal efficiency in the presence of O_2. The oxidation of Hg^0 on Mn O x/TiO_2 follows the Mars–Maessen and Langmuir–Hinshelwood mechanisms. | Shibo Zhang Yongchun Zhao Zonghua Wang Junying Zhang Lulu Wang Chuguang Zheng | 2017 | Journal of Environmental Sciences2017，29，3： | 11 |
| 6 | Single-Atom Catalysts for Electrochemical Hydrogen Evolution Reaction: Recent Advances and Future Perspectives显示文摘Hydrogen,a renewable and outstanding energy carrier with zero carbon dioxide emission,is regarded as the best alternative to fossil fuels.The most preferred route to large-scale production of hydrogen is by water electrolysis from the intermittent sources(e.g.,wind,solar,hydro,and tidal energy).However,the efficiency of water electrolysis is very much dependent on the activity of electrocatalysts.Thus,designing high-effective,stable,and cheap materials for hydrogen evolution reaction(HER)could have a substantial impact on renewable energy technologies.Recently,single-atom catalysts(SACs)have emerged as a new frontier in catalysis science,because SACs have maximum atom-utilization efficiency and excellent catalytic reaction activity.Various synthesis methods and analytical techniques have been adopted to prepare and characterize these SACs.In this review,we discuss recent progress on SACs synthesis,characterization methods,and their catalytic applications.Particularly,we highlight their unique electrochemical characteristics toward HER.Finally,the current key challenges in SACs for HER are pointed out and some potential directions are proposed as well. | Zonghua Pu Ibrahim Saana Amiinu Ruilin Cheng Pengyan Wang Chengtian Zhang Shichun Mu Weiyue Zhao Fengmei Su Gaixia Zhang Shijun Liao Shuhui Sun | 2020 | Nano-Micro Letters2020，12，2： | 10 |
| 7 | Construction of multiform scFv antibodies using linker peptide显示文摘Multiform single chain variable fragments (scFvs) including different length linker scFvs and bispecific scFv were constructed. The linker lengths of 0, 3, 5, 8, 12, and 15 amino acids between VH and VL of antideoxynivalenol (anti-DON) scFv were used to analyze the affinities of scFvs. The affinity constants of these scFvs increased when the linker was lower than 12 amino acids. The affinity constant would not change when the linker was longer than 12 amino acids. Fusion gene of anti-DON scFv and antizearalenone (anti-ZEN) scFv was also constructed through connection by a short peptide linker DNA to express a bispecific scFv. The affinity constants assay showed that the two scFvs of fusion bispecific scFv remained their own affinity compared to their parental scFvs. Competitive direct enzyme linked immunosorbent assay was used to detect DON and ZEN in contaminated wheat (Triticum aestivum L.) samples, and the results indicated that this bispecific scFv was applicable in DON and ZEN detection. This work confirmed that bispecific scFv could be successfully obtained, and might also have an application in diagnosing fungal infection, and breeding transgenic plants. | Shihua Wang Cengjie Zheng Ying Liu Huirong Zheng Zonghua Wang | 2008 | Journal of Genetics and Genomics2008，35，5： | 8 |
| 8 | Development of the general chapters of the Chinese Pharmacopoeia 2020 edition: A review显示文摘The Chinese Pharmacopoeia 2020 edition was reviewed and approved by the National Medical Products Administration and the National Health Commission of the People’s Republic of China in July 2020.The current edition was officially implemented on December 30,2020.The general chapters of the Chinese Pharmacopoeia discuss the general testing methods and guidelines,which are the common requirements and basis for the implementation of drug standards in the Chinese Pharmacopoeia.Owing to adherence to the principles of scientificity,versatility,operability,and sustainable development,there is an improvement in the general chapters of the 2020 edition over those of the previous editions.Further,the application of advanced and mature analytical techniques has expanded,the development of testing methods for exogenous pollutants in traditional Chinese medicines has been strengthened,and technical requirements are now better harmonized with international standards.The updated edition provides technical and methodological support to ensure safety,effectiveness,and control of pharmaceuticals in China and will play an important and active role in encouraging the application of advanced technologies,improving the quality control of medicines,and strengthening the means of drug regulation in China.This review provides a comprehensive introduction of the main features of and changes to the general chapters in the Chinese Pharmacopoeia 2020 edition and aims to provide reference for its correct understanding and accurate implementation. | Xinyi Xu Huayu Xu Yue Shang Ran Zhu Xiaoxu Hong Zonghua Song Zhaopeng Yang | 2021 | Journal of Pharmaceutical Analysis2021，11，4： | 6 |
| 9 | PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae显示文摘 | Jiandong Bao Meilian Chen Zhenhui Zhong Wei Tang Lianyu Lin Xingtan Zhang Haolang Jiang Deyu Zhang Chenyong Miao Haibao Tang Jisen Zhang Guodong Lu Ray Ming Justice Norvienyeku Baohua Wang Zonghua Wang | 2017 | Molecular Plant2017，10，11： | 5 |
| 10 | Comparative QTL analysis of maize seed artificial aging between an immortalized F_2 population and its corresponding RILs显示文摘Seed aging decreases the quality and vigor of crop seeds,thereby causing substantial agricultural and economic losses in crops.To identify genetic differences in seed aging between homozygotes and heterozygotes in maize,the seeds of a set of recombinant inbred lines(RILs) and an immortalized F_2(IF_2) population were subjected to artificial aging treatments for 0,2,3,and 4 days under 45℃ and 85%relative humidity and seed vigor was then evaluated in a field experiment.Seed vigor of all entries tested decreased sharply with longer aging treatment and seed vigor decreased more slowly in heterozygotes than in homozygotes.Forty-nine QTL were detected for four measured seed vigor traits in the RIL(28QTL) and IF_2(21 QTL) populations.Only one QTL,qGP5,was detected in both populations,indicating that the genes involved in anti-aging mechanisms differed between inbred lines and hybrids.Several QTL were identified to be responsible for multiple seed vigor traits simultaneously in the RIL and IF_2 populations under artificial aging conditions.These QTL may include major genes for seed vigor or seed aging.QTL qVI4 b and qGE3 a detected in the RIL population coincided with genes ZmLOX1 and ZmPLD1 in the same respective chromosomal regions.These QTL would be useful for screening for anti-aging genes in maize breeding. | Bin Wang Zhanhui Zhang Zhiyuan Fu Zonghua Liu Yanmin Hu Jihua Tang | 2016 | The Crop Journal2016，4，1： | 5 |
| 11 | ZIF-67 derived hollow Ni-Co-Se nano-polyhedrons for flexible hybrid supercapacitors with remarkable electrochemical performances显示文摘Nano-polyhedral NiSe2/CoSe2(Ni-Co-Se) with hollow architectures are synthesized by selenizing the precursors of Ni-Co bimetallic hydroxides that are directly derived from ZIF-67.The as-fabricated Ni-Co-Se electrodes exhibit high specific capacitance of 1668 F/g at 1 A/g accompanying with outstanding rate capability(about 82.8% retention of the initial capacity at 20 A/g).The corresponding Ni-Co-Se//AC all-solid-state hybrid supercapacitors are assembled by directly using the Ni-Co-Se on carbon fabric as the positive electrode,which deliver high energy density and power density(38.5 Wh/kg at 802.1 W/kg,32.0 Wh/kg at 8008.8 W/kg),excellent cyclic stability(82.3% retention after 5000 cycle) and robust mechanical flexibility(no obvious attenuation at bending to different angles).This work will provide a new and smart route for constructing transition metal selenides for supercapacitor devices. | Guangmeng Qu Xixi Zhang Guotao Xiang Yunrui Wei Jiangmei Yin Zonghua Wang Xiaoli Zhang Xijin Xu | 2020 | Chinese Chemical Letters2020，31，7： | 3 |
| 12 | The effect of pH on the sorption of gold nanoparticles on illite显示文摘Sorption between nanoparticles(NPs)and minerals may critically affect the migration of associated elements as well as the environmental impact of NPs.Since illite is widely present in soil,sediment,and water,we have experimentally investigated the sorption behavior of citrate-coated gold nanoparticles(AuNPs)as model NPs on illite under different pH and mineral mass conditions.We demonstrated that sorption of these negatively charged AuNPs strongly depended on the suspension pH.At pH above 8,which coincided with the apparent point of zero charge(pH 7.9)of our illite sample,only marginal sorption of AuNPs was observed.At pH 3-8,significant sorption of AuNPs on illite was found,with almost complete sorption occurring at more acidic conditions(pH 3-4).TEM observations revealed that sorption took place through the attachment AuNPs on illite edges.At pH 2,AuNPs mostly formed chain-like fused structures and precipitated out of the suspension.Based upon the above pH dependence,residual organic ligand content after sorption,and complementary sorption results with positively charged AuNPs,we conclude that the sorption process is mainly driven by the electrostatic attraction between negatively charged AuNPs and positively charged illite edges,with possible competitive involvement of citrate molecules.We expect that our findings will improve our understanding of NP-mineral interaction and the environmental fate of NPs. | Yuhong Fu Quan Wan Zonghua Qin Xin Nie Wenbin Yu Shanshan Li | 2020 | Acta Geochimica2020，39，2： | 2 |
| 13 | Tunable Ru-Ru2P heterostructures with charge redistribution for efficient pH-universal hydrogen evolution显示文摘Designing synergistic heterogeneous catalytic interfaces is the key to developing highly compatible pH-universal electrocatalysts for complex chemical environments.Our theoretical calculation results demonstrate that the Ru-Ru2P heterointerface can not only promote the redistribution of charges,but also reduce the d-band center,and then enhances the adsorption capacity of the key intermediate.However,in situ and facile synthesis of Ru-Ru2P heterostructures is severely limited by thermodynamic obstacles.Herein,we propose a molten salt-assisted catalytic synthesis scheme,and successfully build a series of homologous metallic Ru-Ru2P heterostructure catalysts with different molar ratios of Ru to P under atmospheric pressure and low-temperature(400C).The resultant Ru-Ru2P with rich heterostructures show the Pt-like HER performance in different pH media.Particularly,it is prominent under alkaline conditions(18 mV@10 mA cm^(2)),which outperforms the Pt catalyst(37 mV@10 mA cm^(2)).Furthermore,Ru-Ru2P heterostructures also show certain potential in the electrolysis of seawater to produce hydrogen.This work represents a significant supplement of high-efficiency pH-universal HER catalysts,and provides a new light on interface engineering in energy technology fields and beyond. | Ding Chen Ruohan Yu Ruihu Lu Zonghua Pu Pengyan Wang Jiawei Zhu Pengxia Ji Dulan Wu Jinsong Wu Yan Zhao Zongkui Kou Jun Yu Shichun Mu | 2022 | InfoMat2022，4，5： | 2 |
| 14 | A Survey of Neuromorphic Computing Based on Spiking Neural Networks显示文摘Neuromorphic computing aims to build digital or analog computer systems that emulate or simulate the biological brain, in order to achieve high performance and low power consumption for intelligent information processing applications. This article reviews on neuromorphic computing based on Spiking neural networks(SNNs), including its history of development, common neuron models, major research projects, neuromorphic sensors, and applications in brain-computer Interfaces. | ZHANG Ming GU Zonghua PAN Gang | 2018 | Chinese Journal of Electronics2018，27，4： | 2 |
| 15 | Signal response amplification of scale-free networks显示文摘In many animals and insects, hearing is very acute to the faintest of sounds; the underlying mechanism can be explained by self-tuning. Recently, signal response amplification has been shown to be implemented through networks exhibiting scale-free topology, which has potential applications in artificial information processing systems and devices. We review in this paper the main results obtained in networked double-well oscillators and briefly discuss future research directions. | LIU ZongHua | 2011 | Chinese Science Bulletin2011，56，34： | 2 |
| 16 | 3-D imaging and modeling (Part Ⅰ) : Acquisition and registration 显示文摘 | Peng Xiang Zhang Zonghua Tiziani H J | 2002 | Optik-lnternational Journal for Light and Electron Optics2002，113，10： | 1 |
| 17 | ROP/RAC GTPase:an old new master regulator for plant signaling显示文摘 | Ying Gu Zonghua Wang Zhenbiao Yang | 2004 | Current Opinion in Plant Biology2004，7，： | 1 |
| 18 | 3D fingerprint imaging system based on full-field fringe projection profilometry显示文摘 | Shujun Huang Zonghua Zhang Yan Zhao Jie Dai Chao Chen Yongjia Xu E. Zhang Lili Xie | 2014 | Optics and Lasers in Engineering2014，，： | 1 |
| 19 | Spatial multi-scaled chimera states of cerebral cortex network and its inherent structure-dynamics relationship in human brain显示文摘Human cerebral cortex displays various dynamics patterns under different states,however the mechanism how such diverse patterns can be supported by the underlying brain network is still not well understood.Human brain has a unique network structure with different regions of interesting to perform cognitive tasks.Using coupled neural mass oscillators on human cortical network and paying attention to both global and local regions,we observe a new feature of chimera states with multiple spatial scales and a positive correlation between the synchronization preference of local region and the degree of symmetry of the connectivity of the region in the network.Further,we use the concept of effective symmetry in the network to build structural and dynamical hierarchical trees and find close matching between them.These results help to explain the multiple brain rhythms observed in experiments and suggest a generic principle for complex brain network as a structure substrate to support diverse functional patterns. | Siyu Huo Changhai Tian Muhua Zheng Shuguang Guan Changsong Zhou Zonghua Liu | 2021 | National Science Review2021，8，1： | 1 |
| 20 | Enzymatic activity enhancement of non-covalent modified superoxide dismutase and molecular docking analysis显示文摘 | QIU Yanzi HUANG Zonghua SONG Fajun | 2012 | Molecules2012，17，： | 1 |
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