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| 1 | Bone mineral density and disorders of mineral metabolism in chronic liver disease显示文摘AIM:To estimate the prevalence and identify the risk factors for metabolic bone disease in patients with cirrhosis.METHODS:The study was performed on 72 Indian patients with cirrhosis(63 male, 9 female;aged < 50 years).Etiology of cirrhosis was alcoholism(n = 37), hepatitis B(n = 25) and hepatitis C(n = 10).Twenty-three patients belonged to Child class A, while 39 were in class B and 10 in class C.Secondary causes for metabolic bone disease and osteoporosis were ruled out.Sunlight exposure, physical activity and dietary constituents were calculated.Complete metabolic profiles were derived, and bone mineral density(BMD) was measured using dual energy X ray absorptiometry.Low BMD was defined as a Z score below-2.RESULTS:Low BMD was found in 68% of patients.Lumbar spine was the most frequently and severely affected site.Risk factors for low BMD included low physical activity, decreased sunlight exposure, and low lean body mass.Calcium intake was adequate, with unfavorable calcium:protein ratio and calcium:phosphorus ratio.Vitamin D deficiency was highly prevalent(92%).There was a high incidence of hypogonadism(41%).Serum estradiol level was elevated significantly in patients with normal BMD.Insulin-like growth factor(IGF) 1 and IGF binding protein 3 levels were below the age-related normal range in both groups.IGF-1 was signiflcantly lower in patients with low BMD.Serum osteocalcin level was low(68%) and urinary deoxypyridinoline to creatinine ratio was high(79%), which demonstrated low bone formation with high resorption.CONCLUSION:Patients with cirrhosis have low BMD.Contributory factors are reduced physical activity, low lean body mass, vitamin D def iciency and hypogonadism and low IGF-1 level. | Joe George Hosahithlu K Ganesh Shrikrishna Acharya Tushar R Bandgar Vyankatesh Shivane Anjana Karvat Shobna J Bhatia Samir Shah Padmavathy S Menon Nalini Shah | 2009 | World Journal of Gastroenterology2009，15，28： | 15 |
| 2 | Prognostic impact of atrial fibrillation on clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease显示文摘Atrial fibrillation(AF) is the most common type of sustained arrhythmia,which is now on course to reach epidemic proportions in the elderly population. AF is a commonly encountered comorbidity in patients with cardiac and major non-cardiac diseases. Morbidity and mortality associated with AF makes it a major healthcare burden. The objective of our article is to determine the prognostic impact of AF on acute coronary syndromes,heart failure and chronic kidney disease. Multiple studies have been conducted to determine if AF has an independent role in the overall mortality of such patients. Our review suggests that AF has an independent adverse prognostic impact on the clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease. | Nileshkumar J Patel Aashay Patel Kanishk Agnihotri Dhaval Pau Samir Patel Badal Thakkar Nikhil Nalluri Deepak Asti Ritesh Kanotra Sabeeda Kadavath Shilpkumar Arora Nilay Patel Achint Patel Azfar Sheikh Neil Patel Apurva O Badheka Abhishek Deshmukh Hakan Paydak Juan Viles-Gonzalez | 2015 | World Journal of Cardiology2015，7，7： | 2 |
| 3 | End-stage renal disease is associated with increased post endoscopic retrograde cholangiopancreatography adverse events in hospitalized patients显示文摘AIM To determine if end-stage renal disease (ESRD) is a risk factor for post endoscopic retrograde cholangio-pancreatography (ERCP) adverse events (AEs). METHODS We performed a retrospective cohort study using the Nationwide Inpatient Sample (NIS) 2011-2013. We identified adult patients who underwent ERCP using the International Classification of Diseases 9^(th) Revision (ICD-9-CM). Included patients were divided into three groups: ESRD, chronic kidney disease (CKD), and control. The primary outcome was post-ERCP AEs including pancreatitis, bleeding, and perforation determined based on specific ICD-9-CM codes. Secondary outcomes were length of hospital stay, in-hospital mortality, and admission cost. AEs and mortality were compared using multivariate logistic regression analysis.RESULTS There were 492175 discharges that underwent ERCP during the 3 years. The ESRD and CKD groups contained 7347 and 39403 hospitalizations respectively, whereas the control group had 445424 hospitalizations. Post-ERCP pancreatitis (PEP) was significantly higher in the ESRD group (8.3%) compared to the control group (4.6%) with adjusted odd ratio (aOR) = 1.7 (95% CI: 1.4-2.1, ~aP < 0.001). ESRD was associated with significantly higher ERCP-related bleeding (5.1%) compared to the control group 1.5% (aOR = 1.86, 95%CI: 1.4-2.4, ~aP < 0.001). ESRD had increased hospital mortality 7.1% vs 1.15% in the control OR = 6.6 (95%CI: 5.3-8.2, ~aP < 0.001), longer hospital stay with adjusted mean difference (aMD) = 5.9 d (95% CI: 5.0-6.7 d, ~aP < 0.001) and higher hospitalization charges aMD = $+82064 (95%CI: $68221-$95906, ~aP < 0.001). CONCLUSION ESRD is a risk factor for post-ERCP AEs and is associated with higher hospital mortality. Careful selection and close monitoring is warranted to improve outcomes. | Tarek Sawas Fateh Bazerbachi Samir Haffar Won K Cho Michael J Levy John A Martin Bret T Petersen Mark D Topazian Vinay Chandrasekhara Barham K Abu Dayyeh | 2018 | World Journal of Gastroenterology2018，24，41： | 2 |
| 4 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011，，13： | 2 |
| 5 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis显示文摘 | Mary Eapen Vanderson Rocha Guillermo Sanz Andromachi Scaradavou Mei-Jie Zhang William Arcese Anne Sirvent Richard E Champlin Nelson Chao Adrian P Gee Luis Isola Mary J Laughlin David I Marks Samir Nabhan Annalisa Ruggeri Robert Soiffer Mary M Horowitz Eli | 2010 | Lancet Oncology2010，，7： | 2 |
| 6 | Cross-linked nanocomposite polymer electrolytes reinforced with cellulose whiskers显示文摘 | Samir M Alloin F Sanchez J Y | 2004 | Macro molecules2004，37，13： | 1 |
| 7 | ORP-based oxygenation for sulfide control in anaerobic treatment of high-sulfate wastewater 显示文摘 | Samir K K Huang J C | 2003 | Water Res2003，37，10： | 1 |
| 8 | p53-dependentexpression of the stress-induced protein ( SIP) 显示文摘 | Tomasini R Samir A A Pebusque M J ef al | 2002 | Eur J CellBiol2002，81，5： | 1 |
| 9 | Biomimefic foams of high mechanical performance based on nanostrnctured cell walls reinforced by native cellulose nanofibrils 显示文摘 | Svagan A J Samir M A S Berglund L A | 2008 | Advanced Materials2008，20，7： | 1 |
| 10 | Coplanar Waveguides and Microwave Inductors on Silicon Substrate显示文摘 | El-Ghazaly Samir M Dorn Steve J Michael Dydyk | 1995 | IEEE Transactions on Microwave Theory and Techniques1995，43，9： | 1 |
| 11 | Adaptive interference suppression in multiuser wireless OFDM systems using antenna arrays显示文摘 | Daniel J Marchok Huang Yih-Fang | 1999 | IEEE Trans on Signal Processing1999，47，12： | 1 |
| 12 | Finite element analysis of automotive cushion discs显示文摘 | Samir S Emmanuel B Fortin J | 2009 | Thin-Walled Structures2009，47，4： | 1 |
| 13 | Platelet Rich Concentrate: Basic Science and Current Clinical Applications显示文摘 | Samir Mehta J Tracy Watson | 2008 | Journal of Orthopaedic Trauma2008，，6： | 1 |
| 14 | Complexed prostate-specific antigen as a staging tool: results based on a multicenter prospective evaluation of complexed prostate-specific antigen in cancer diagnosis显示文摘 | Samir S Taneja Elias I Hsu Carol D Cheli Paul Walden Georg Bartsch Wolfgang Horninger Richard J Babaian Herbert A Fritsche Stacy Childs Thomas A Stamey Lori J Sokoll Daniel W Chan Michael K Brawer Alan W Partin Herbert Lepor | 2002 | Urology2002，，4： | 1 |
| 15 | Rapid determination of benzo (a) pyrene in olive oil samples with solid-phase extraction and low-pressure, wide-bore gas chromatography - mass spectrometry and fast liquid chromatography with fluorescence detection 显示文摘 | MACIEJ J B SAMIR A E H ZEYARD E | 2004 | J Chromatogr A2004，1026，： | 1 |
| 16 | Treatment Protocol for Open AO/OTA Type C3 Pilon Fractures With Segmental BoneLoss显示文摘 | Gardner Michael J MD Mehta Samir MD Barei David P MD | | 0，，7： | 1 |
| 17 | Postoperative Mediastinitis in Children: Epidemiology, Microbiology and Risk Factors for Gram-Negative Pathogens显示文摘 | Caroline B. Long Samir S. Shah Ebbing Lautenbach Susan E. Coffin Sarah Tabbutt J William Gaynor Louis M. Bell | 2005 | The Pediatric Infectious Disease Journal2005，，4： | 1 |
| 18 | Treatment Protocol for Open AO/OTA Type C3 Pilon Fractures With Segmental Bone Loss 显示文摘 | Gardner Michael J MD Mehta Samir MD Barei David P MD | 2008 | Journal of Orthopaedic Trauma2008，22，7： | 1 |
| 19 | Shock synthesis of nanodiamonds from carbon precursors: identification of carbines显示文摘 | Donnet J B Fousson E Samirant M | 2000 | Comptes Rendus de IAcademie des Sciences-Serie IIC-Chemistry2000，，3： | 1 |
| 20 | Biomimetic polysaccharide nanoco iaaposites of high cellulose content and high toughness 显示文摘 | Svagan A J Azizi Samir M A S Berglund L A | 2007 | Biomacromolecules2007，8，8： | 1 |
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