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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Antimicrobial activity of cotton and silk fabric with herbal extract by micro encapsulation显示文摘Objective:To explore the antimicrobial activity of microcapsules encapsulated with mixture of herbs like neem,tulsi and turmeric,and its application on cellulosic fabric in the form of microcapsules.Methods:The microcapsules were prepared from the mixture of herbs by plain diffusion method,a natural encapsulation technique with yeast and applied on cotton and silk fabric by pad-dry-cure method.The microcapsules were fixed on cotton and silk fabric using the binder UF Silpure FBR-5(PA)B at 120℃.The antimicrobial activities of the finished fabric were assessed by using three types of bacteria including Staphylococcus aureus,Escherichia coli and Pseudomonas.Results:The results of antimicrobial activity from the tests including parallel streak method and disc diffusion method showed that activity of the mixture of herbs was very effective among the three types of bacteria selected,and the antimicrobial activity of prepared microcapsule against Pseudomonas was very good.Conclusions:The herbal microcapsule treated fabric could be applied in the field of medicine.The scanning electron microscope photographs ensure the fixing of the microcapsules firmly in the yarn structure of plain woven cotton and silk fabric. | Saraswathi R Krishnan PN Dilip C | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，2： | 3 |
| 3 | Electrospinning of curcumin loaded chitosan/poly (lactic acid) nanofilm and evaluation of its medicinal characteristics显示文摘curcumin 装载了 chitosan/poly (乳的酸)(PLA ) nanofibers 用 electrospinning 被生产。BoxBehnken 试验性的设计被用于变量的优化(1, 0, + 1 编码水平) 相似 chitosan/PLA 力量(% w/v ) , curcumin 力量(% w/v ) 和应用电压(kV ) 到获得一致纤维直径。nanofibers 的形态学被 SEM 显示出。分子的相互作用和 curcumin 的各化学的化合物的存在装载了 chitosan/PLA 纤维被 FTIR 和 EDX 分析描绘。抗氧化剂,药版本并且在 vitro cytotoxicity,测试被执行评估将被用于创伤愈合的 nanofibers 的适用性。在愈合弯屈在切除和切口上学习的 vivo,创伤在给创伤区域的重要减小看是否的老鼠模型上创造了与相比未经治疗。更好愈合的效率能被归因于 curcumin 和 chitosan 的存在。 | Bhaarathi DHURAI Nachimuthu SARASWATHY Ramasamy MAHESWARAN Ponnusamy SETHUPATHI Palanisamy VANITHA Sukumar VIGNESHWARAN~, and Venugopal RAMESHBABU | 2013 | Frontiers of Materials Science2013，7，4： | 2 |
| 4 | Echovirus serotypes circulating in Malaysia from 2002 to 2013显示文摘Objective:To identify the circulating serotypes of human echovinis in Malaysia from 2002 in 2013.Methods:A toial of 31 retrospective samples from non-polio acute flacid paralysis,hand-food-and-mouth disease,viral meningitis and enterovirus cases were subjected to amplification of partial VPI gene by RT-PCR.Results:Sequencing and phylogeneiic analysis of the partial sequences identified presence of human echovinis and human coxsackie viruses.It was found that echovinis 11 was the commonly circulating serotype followed by echovinis6.echovinis 7.echovinis 3.echovinis 9.echovinis 30 and echovinis I in decreasing order.Additionally two types of human coxsackie virus isolates were detected which were coxsackie A24 and B3.Condusions:From the findings,there is a possibility that echovinis 11 is the predominant serotype among Malaysian patients with echovinis infection.However,a larger sample size will yield a more confident result to support this evidence.____________________ | Jeyanthi Suppiah TS Saraswathy Subramaniam Amry Khursany Ismail Apandi Yusof Zainah Sa'at | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，3： | 2 |
| 5 | Concise review on short bowel syndrome: Etiology, pathophysiology, and management显示文摘Adults have approximately 20 feet of small intestine,which is the primary site for absorbing essential nutrients and water.Resection of the intestine for any medical reason may result in short bowel syndrome(SBS),leading to loss of major absorptive surface area and resulting in various malabsorption and motility disorders.The mainstay of treatment is personalized close dietary management.Here we present SBS with its pathophysiology and different nutritional management options available.The central perspective of this paper is to provide a concise review of SBS and the treatment options available,along with how proper nutrition can solve major dietary issues in SBS and help patients recover faster. | Saraswathi Lakkasani Deeksha Seth Imran Khokhar Masara Touza Theodore Jr Dacosta | 2022 | World Journal of Clinical Cases2022，10，31： | 2 |
| 6 | Hibiscus vitifolius (Linn.) root extracts shows potent protective action against anti-tubercular drug induced hepatotoxicity显示文摘 | Anbu Jeba Sunilson John Samuel Syam Mohan Dinesh Kumar Chellappan Anandarajagopal Kalusalingam Saraswathi Ariamuthu | 2012 | Journal of Ethnopharmacology2012，，1： | 2 |
| 7 | A Suevey on Con- tent based Medical Image Retrieval for Mri Brain Images 显示文摘 | Sharmila G Saraswathi D Ramkumar R | 2014 | International Journal of Research in Engineering and Technology2014，3，19： | 1 |
| 8 | ICGA-PSOELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented显示文摘 | Saraswathi S Sundaram s Sundararjan N | 2011 | IEEE/ACM Transactions on Computational Biology and Bioinformatics2011，8，2： | 1 |
| 9 | Chemo-and regioselective conversion of epoxides to carbonyl compounds in 5 M lithium perchlorate-diethyl ether medium 显示文摘 | R Sudha K Malola Narasimhan Geetha Saraswathy | 1996 | J Org Chem1996，61，： | 1 |
| 10 | Eosinophils in health and disease: An overview 显示文摘 | Saraswathi TR Nalinkumar S Ranganathan K | 2003 | J Oral Maxillofacial Pathol2003，7，2： | 1 |
| 11 | Formulation and evaluation of herbal gel of Pothos scandens Linn显示文摘Objective:To formulate Pothos scandens Linn(P.scandens) leaf extract in to a gel and investigate their burn wound healing activity.Methods:Ethanolic extract of dried leaves of P. scandens were subjected to priliminery phytochemical evaluation and wound healing activities studies.Different gel formulations of ethanolic extract of P.scandens(4%w/v) were prepared using polymers carbopol 934 and carbopol 940 bv varying their concentration.These formulations were evaluated for physical parameters,drug content.pH,viscosity,extrudability.spreadability. primary skin irritation,pharmacological activity and stability.Results:Wound healing studies of ethanolic extract revealed that P.scandens treated animals were found to epithelise in 22 days while the solvent control and the untreated rats epithelise within 35 and 40 days respectively. The formulation with 1.5%w/w carbopol 934 was found to be more promising as it shows better physicochemical characteristics,higher pharmacological activity and stability compared to other formulations.Conclusions:P.scandens alcoholic extract shows significant improvement in burn wound contraction and hence this is a promising candidate in burn wound healing. | Mohammed Haneefa KP Shahima Hanan K Saraswathi R Guru Prasad Mohanta Chandini Nayar | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，12： | 1 |
| 12 | Multifunctional drug nanocarriers formed by cRGD-conjugated betaCD-PAMAM-PEG for targeted cancer therapy 显示文摘 | Saraswathy M Knight G T Pilla S | 2015 | Colloids and surfaces B Biointerfaces2015，126，： | 1 |
| 13 | Hepatoprotective and antioxidant activity of N -acetyl cysteine in carbamazepine-administered rats 显示文摘 | Maheswari E Saraswathy GR Santhranii T | 2014 | Indian J Pharmacol2014，46，2： | 1 |
| 14 | Yield maximization in cassava through a systematic approach in fertilizer use显示文摘 | John K S Venugopal V K Saraswathi P | | 0，，： | 1 |
| 15 | MTHFR C677T polymorphism and its homocysteine‐driven effect on blood pressure显示文摘 | K. N. Saraswathy Priyanka Rani Garg Kabita Salam Shipra Joshi Suraj Singh Huidrom Pradeep Kumar Ghosh | 2014 | Int J Stroke2014，，： | 1 |
| 16 | An estimation of the diffusivity of silica fume concrete显示文摘 | Ha-Won Song Jong-Chul Jang Velu Saraswathy | 2007 | Building and Environment2007，，42： | 1 |
| 17 | Studies on the aspects of chloride ion determination in different types of concrete under macro-cell corrosion conditions显示文摘 | MURALIDHARAN S VEDALAKSHMI R SARASWATHI V | 2005 | Building and Environment2005，40，9： | 1 |
| 18 | Studies on the Corrosion Resistance of Reinforced Steel in Concrete with Ground Granulated Blasted-furnace Slag-an Overview显示文摘 | Ha-Won Song Velu Saraswathy | 2006 | Journal of Hazardous Materials2006，133，2： | 1 |
| 19 | Neuroglobin protection in retinal ischemia显示文摘 | CHAN A S SARASWATHY S REHAK M | 2012 | Invest Ophthalmol Vis Sci2012，53，2： | 1 |
| 20 | Immunohistocemical evaluation of mast cells and vascular endothelial proliferation in oral pre- cancerous lesion- leukoplakia 显示文摘 | Sathyakumar M Sriram G Saraswathi T | 2012 | J Oral Maxillofac Pathol2012，16，3： | 1 |
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