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| 1 | Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: Echinococcosis multilocularis Ulm classification-ultrasound显示文摘AIM: To establish an ultrasonographic classification based on a large sample of patients with confirmed hepatic alveolar echinococcosis(AE).METHODS: Clinical data and ultrasonography(US) findings of 185 patients(100 males; 85 females; mean age at diagnosis: 51.4 ± 17.6 years; mean age at time of US examination: 58.7 ± 18.2 years) were retrospectively reviewed with respect to the US morphology of hepatic AE lesions. The sonomorphological findings were grouped according to a five-part classification scheme.RESULTS: Application of the new classification resulted in the following distribution of sonomorphological patterns among the patients examined: hailstorm(54.1%); pseudocystic(13.5%); ossification(13.0%); hemangioma-like(8.1%); and metastasis-like(6.5%). Only 4.9% of lesions could not be assigned to a sonomorphological pattern.CONCLUSION: The sonomorphological classification proposed in the present study facilitates the diagnosis,interpretation and comparison of hepatic alveolar echinococcosis in routine practice and in the context of scientific studies. | Wolfgang Kratzer Beate Gruener Tanja EM Kaltenbach Sarina Ansari-Bitzenberger Peter Kern Michael Fuchs Richard A Mason Thomas FE Barth Mark M Haenle Andreas Hillenbrand Suemeyra Oeztuerk Tilmann Graeter | 2015 | World Journal of Gastroenterology2015，21，43： | 16 |
| 2 | Long-term follow-up of distal intestinal obstruction syndrome in cystic fibrosis显示文摘AIM: To investigate the long-term follow-up of distal intestinal obstruction syndrome(DIOS) in Israeli cystic fibrosis(CF) patients.METHODS: This is a multi-center,comparative,retrospective study in which we reviewed the medical records of all CF patients from three major CF centers in Israel who were treated in the period from 1980 to 2012.Patients diagnosed with DIOS were defined as the study group.The patients were diagnosed with DIOS based on their clinical presentation and typical findings on either abdominal X-ray or computerized tomography scan.For the control group,CF patients with no DIOS were matched to the patients in the study group for age,sex,and cystic fibrosis transmembrane conductance regulator(CFTR) mutations.For both groups,the collected data included age,sex,CFTR genotype,weight,height,and body mass index.Clinical data included respiratory function tests in the last five years prior to the study,respiratory function test immediately before and after the DIOS event,number of hospitalizations,sputum culture results,and CFrelated conditions diagnosed according to the CF clinical practice guidelines.In the study group,data on the DIOS treatment and tendency for DIOS recurrence were also analyzed.RESULTS: The medical charts for a total of 350 CF patients were reviewed.Of the 350 CF patients,26(7.4%) were diagnosed with DIOS.The control group included 31 CF patients with no DIOS diagnosis.The mean follow-up period was 21.6 ± 8.2 years.The total of DIOS episodes in the follow-up period was 60.The distribution of DIOS episodes was as follows: 6/26(23.1%) study patients had one episode of DIOS intheir lifetime,7/26(26.9%) had two episodes,7/26(26.9%) had three episodes,and 6/26(23.1%) had four or more episodes.Compared to the control group,DIOS patients had a significantly higher incidence of meconium ileus in the past(65.4% vs 0%,respectively,P < 0.02),more Aspergillus spp.colonization(34.6% vs 3.2%,respectively,P < 0.02),and a higher number of hospitalizations due to respiratory exacerbations(8.6 vs 6.2 mean total hospitalizations per follow-up period,respectively,P < 0.02).No other significant differences were found between the control and study groups.The conservative treatment of DIOS,which mainly includes hydration and stool softeners,was successful in 82% of the episodes.The survival rate was similar for both groups.CONCLUSION: CF patients with DIOS suffer from recurrent hospitalizations and airway pathogen acquisition.Although recurrence of DIOS is common,conservative treatment is successful in most patients. | Moran Lavie Tzipora Manovitz Daphna Vilozni Sarina Levy-Mendelovich Ifat Sarouk Ilana Weintraubv David Shoseyov Malena Cohen-Cymberknoh Joseph Rivlin Ori Efrati | 2015 | World Journal of Gastroenterology2015，21，1： | 10 |
| 3 | Assessing the impact of arthropod natural enemies on crop pests at the field scale显示文摘有许多原因,我们发现方法保存,是重要的,并且更好利用无脊椎的庄稼害虫的生来的敌人。当前,生来的敌人影响的措施很少被合并到声称检验害虫控制的研究。大多数研究检验害虫和生来的敌人存在或丰富然后品质上推断影响。当这提供有用数据探讨生态的问题的一个范围时,影响的一项措施为指导害虫管理决策是批评的。经常,一些很简单的技术能被用来获得生来的敌人影响的估计。我们使用了笼子,限制生来的敌人或猎物运动的障碍,生来的敌人攻击的直接观察,和哨兵的基于地的研究的现在的例子估计的猎物项目死亡。在每研究使用的生来的敌人影响的措施需要被定制到农民和他们面对的特定的害虫问题的需要。例如,归因于生来的敌人的死亡的大小可能不比预定和在季节之间的那死亡的一致性重要。定制影响评价将导致简单地不提供怎么保存生来的敌人,但是怎么把这些生来的敌人用作决策的不可分的部分的一般信息的研究结果。 | Sarina Macfadyen Andrew P. Davies Myron P. Zalucki | 2015 | Insect Science2015，22，1： | 7 |
| 4 | Connecting scales: Achieving in-field pest control from areawide and landscape ecology studies显示文摘Areawide 管理有完成然而,在那里指向害虫的答案的长历史是节肢动物天赋敌人的 areawide 管理的小焦点。显示出在生来的敌人丰富和产地差异之间的一种积极关系的风景生态学研究表明风景依赖者害虫抑制,但是还没有清楚地连接了他们的调查结果到害虫管理或到与要求控制的庄稼联系的害虫的套房。相反焦点经常在单个害虫种类和他们的生来的敌人的模型系统上。我们建议从生来的敌人捕获害虫控制的管理行动可能向前正在来如果:(i) 害虫建筑群和特定的管理行动上的反应和预言者变量焦点的套房;(ii )“the landscape” 的贡献被估计预定和生来的敌人移民并且移民到并且从目标庄稼,以及害虫的数字识别;并且(iii ) 与庄稼发展阶段排列的害虫控制阀值是基准在害虫上测量生来的敌人的影响,接着允许在学习区域之间的比较,和归纳。为了完成害虫控制,我们将需要合并什么从模型害虫和生来的敌人系统的生态的理解被学习了并且与内场害虫管理集成 areawide 风景管理。 | Nancy A. Schellhorn Hazel R. Parry Sarina Macfadyen Yongmo Wang Myron P. Zalucki | 2015 | Insect Science2015，22，1： | 6 |
| 5 | Comparative analysis of the predictive power of different endothelial progenitor cell phenotypes on cardiovascular outcome显示文摘AIM: To compare the predictive power of different endothelial progenitor cell (EPC) phenotypic markers for future cardiovascular events. METHODS: Peripheral blood was collected from 76 consecutive patients with acute coronary syndromes (ACS) who underwent percutaneous coronary intervention in our institute. The various EPC phenotypes of peripheral blood mononuclear cells were CD34+CD133+, CD34+KDR+, and CD 133+KDR+. The outcome endpoint included cardiovascular mortality, recurrent ACS, and hospitalization for decompensated heart failure during a 24-mo follow-up period.RESULTS: CD34+CD133+ cells (P = 0.034), but not CD34+KDR+ (P = 0.35) or CD 133+KDR+ cells (P = 0.19), were found to predict recurrent ACS. We found no correlation between EPCs measured by any of the three phenotypic combinations of accepted CD markers and the total combination of these separate outcomes. CONCLUSION: The EPC CD34+CD133+ phenotype, but not the CD34+KDR+ or the CD 133+KDR+ phenotypes, is predictive of future adverse cardiovascular outcomes. | Shmuel Schwartzenberg Arnon Afek Gideon Charach Ardon Rubinstein Yossi Ben-Shoshan Sarina Kissil Sofia Maisel-Auslender Gad Keren Jacob George | 2010 | World Journal of Cardiology2010，2，9： | 5 |
| 6 | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor显示文摘Glucagon-like peptides(GLP-1 and GLP-2)are two proglucagon-derived intestinal hormones that mediate distinct physiological functions through two related receptors(GLP-1R and GLP-2R)which are important drug targets for metabolic disorders and Crohn's disease,respectively.Despite great progress in GLP-1 R structure determination,our understanding on the differences of peptide binding and signal transduction between these two receptors remains elusive.Here we report the electron microscopy structure of the human GLP-2R in complex with GLP-2 and a Gs heterotrimer.To accommodate GLP-2 rather than GLP-1,GLP-2R fine-tunes the conformations of the extracellular parts of transmembrane helices(TMs)1,5,7 and extracellular loop 1(ECL1).In contrast to GLP-1,the N-terminal histidine of GLP-2 penetrates into the receptor core with a unique orientation.The middle region of GLP-2 engages with TM1 and TM7 more extensively than with ECL2,and the GLP-2 C-terminus closely attaches to ECL1,which is the most protruded among 9 class B G protein-coupled receptors(GPCRs).Functional studies revealed that the above three segments of GLP-2 are essential for GLP-2 recognition and receptor activation,especially the middle region.These results provide new insights into the molecular basis of ligand specificity in class B GPCRs and may facilitate the development of more specific therapeutics. | Wen Sun Li-Nan Chen Qingtong Zhou Li-Hua Zhao Dehua Yang Huibing Zhang Zhaotong Cong Dan-Dan Shen Fenghui Zhao Fulai Zhou Xiaoqing Cai Yan Chen Yan Zhou Sarina Gadgaard Wijnand JCvan der Velden Suwen Zhao Yi Jiang Mette MRosenkilde HEric Xu Yan Zhang Ming-Wei Wang | 2020 | Cell Research2020，30，12： | 4 |
| 7 | Assessing the impact of natural enemies in agroecosystems: toward "real" IPM or in quest of the Holy Grail?显示文摘 | Myron P. Zalucki Michael J. Furlong Nancy A. Schellhorn Sarina Macfadyen Andrew P. Davies | 2015 | Insect Science2015，22，1： | 4 |
| 8 | Campus Vibration in Nanwangshan Campus,China University of Geosciences at Wuhan Monitored by Short-Period Seismometers显示文摘Continuous seismic observations can record seismic waveforms, and ambient noise, for the purposes of earthquake researches and other applications. Here we deploy three digital seismometers(EPS-2) in and around the Nanwangshan Campus of the China University of Geosciences(Wuhan). This network was running from April 9 to May 9 of 2018. During this period, the seismometers recorded the May 4, 2018 M6.9 Hawaii earthquake. From the recorded waveforms, we could observe clearly the P and S arrivals, and the corresponding particle motions. Analysis of continuous observations of ambient noise shows obvious fluctuation of vibration intensity inside of the campus. The campus is quietest from 0 to 5 am. From 5 am on, the vibration intensity increases, and reaches the peak of entire day at 12 am. The amplitude then decreases to a very low level at 19:30 to 20:00 pm, and reaches another strong noisy time at 21:00 to 21:30 pm. After 21:30 pm, the intensity goes down slowly. We also observed seismic signals that were generated by the interaction of speed-control hump cars and ground. By taking the envelope and smooth operations, we observe different characteristics for different car speeds, which suggests that seismic monitoring approaches can be used for speed measurement of cars. This kind of small seismic network running in a real time fashion, would greatly help understanding of the sources of ambient noise at high frequency bands in interested areas. Analysis of a long-term observed dataset, and real time illustration will help to strengthen campus security and high-precision laboratory deployments, and also contribute to research atmosphere in earthquake science. | Lihui Wu Dun Wang Ziguang Lei Jing Fu Shuai Min Xianbing Xu Sarina Bao | 2020 | Journal of Earth Science2020，31，5： | 3 |
| 9 | Safety and Efficacy of Endoscopic Mucosal Therapy With Radiofrequency Ablation for Patients With Neoplastic Barrett’s Esophagus显示文摘 | William J. Bulsiewicz Hannah P. Kim Evan S. Dellon Cary C. Cotton Sarina Pasricha Ryan D. Madanick Melissa B. Spacek Susan E. Bream Xiaoxin Chen Roy C. Orlando Nicholas J. Shaheen | 2013 | Clinical Gastroenterology and Hepatology2013，，6： | 2 |
| 10 | Specifying the role of BAK1-interacting receptor-like kinase 3 in brassinosteroid signaling显示文摘Brassinosteroids(BR) are involved in the control of several developmental processes ranging from root elongation to senescence and adaptation to environmental cues. Thus, BR perception and signaling have to be precisely regulated. One regulator is BRI1-associated kinase 1(BAK1)-interacting receptor-like kinase 3(BIR3). In the absence of BR, BIR3 forms complexes with BR insensitive 1(BRI1) and BAK1.However, the biophysical and energetic requirements for complex formation in the absence of the ligand have yet to be determined. Using computational modeling, we simulated the potential complexes between the cytoplasmic domains of BAK1, BRI1 and BIR3. Our calculations and experimental data confirm the interaction of BIR3 Rewith BAK1 and BRI1, with the BAK1 BIR3 interaction clearly favored. Furthermore, we demonstrate that BIR3 and BRI1 share the same interaction site with BAK1. This suggests a competition between BIR3 and BRI1 for binding to BAK1, which results in preferential binding of BIR3 to BAK1 in the absence of the ligand thereby preventing the active participation of BAK1 in BR signaling. Our model also suggests that BAK1 and BRI1 can interact even while BAK1 is in complex with BIR3 at an additional binding site of BAK1 that does not allow active BR signaling. | Ruth Groβeholz Anna Feldman-Salit Friederike Wanke Sarina Schulze Nina Glockner Birgit Kemmerling Klaus Harter Ursula Kummer | 2020 | Journal of Integrative Plant Biology2020，62，4： | 1 |
| 11 | Addition of probiotics to nor- floxacin does not improve efficacy in the prevention of sponta- neous bacterial peritonitis:a double-blind placebo-controlled randomized-controlled trim 显示文摘 | Pande C Kumar A Sarina SK | 2012 | Eur J Gastroenterol Hepa- tol2012，24，： | 1 |
| 12 | Removal of radioactive iodine from water using Ag2O grafted titanate nanolamina as efficient adsorbent显示文摘 | Bo A Sarina S Zheng Z | 2013 | Journal of Hazardous Materials2013，，： | 1 |
| 13 | Evaluation of water reuse technologies for the textile industry 显示文摘 | SARINA J BRIAN M DAVID A | 2006 | Journal Of Environmental Engineering2006，，3： | 1 |
| 14 | Sleep and rheumatologic disorders 显示文摘 | Abad VC Sarinas PS Guilleminauh C | 2008 | Sleep Med Rev2008，12，： | 1 |
| 15 | Successful application of nitritation/anammox to wastewater with elevated organic carbon to ammonia ratios显示文摘 | Sarina J Siegfried E V Eberhard M | 2014 | Water Research2014，，49： | 1 |
| 16 | Brucellosis显示文摘 | Sarinas PS Chitkara RK | 2003 | Semin Respir lnfect2003，18，3： | 1 |
| 17 | Polysilicon strain- gauge transducers显示文摘 | Gridchin V A Lubimskyi V M Sarina M P | 1992 | Sensors and Actuators A1992，30，： | 1 |
| 18 | Membrane bioreactor for control of volatile organic 显示文摘 | Sarina J Ergas Michael S McGrath | 1997 | Journal of Environmental engineering1997，25，6： | 1 |
| 19 | Successful application of nitritation/anammox to wastewater with elevated organic carbon to ammonia ratios显示文摘 | Sarina Jenni Siegfried E. Vlaeminck Eberhard Morgenroth Kai M. Udert | 2014 | Water Research2014，，： | 1 |
| 20 | Drinking water denitrification using a membrane bioreactor显示文摘 | Sarina J Ergas David E Rheinheimer | 2004 | Water Research2004，，14： | 1 |
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