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| 1 | Gastroesophageal reflux disease and morbid obesity: To sleeve or not to sleeve?显示文摘Laparoscopic sleeve gastrectomy(LSG) has reached wide popularity during the last 15 years, due to the limited morbidity and mortality rates, and the very good weight loss results and effects on comorbid conditions. However, there are concerns regarding the effects of LSG on gastroesophageal reflux disease(GERD). The interpretation of the current evidence is challenged by the fact that the LSG technique is not standardized, and most studies investigate the presence of GERD by assessing symptoms and the use of acid reducing medications only. A few studies objectively investigated gastroesophageal function and the reflux profile by esophageal manometry and 24-h p H monitoring, reporting postoperative normalization of esophageal acid exposure in up to 85% of patients with preoperative GERD, and occurrence of de novo GERD in about 5% of cases. There is increasing evidence showing the key role of the surgical technique on the incidence of postoperative GERD. Main technical issues are a relative narrowing of the mid portion of the gastric sleeve, a redundant upper part of the sleeve(both depending on the angle under which the sleeve is stapled), and the presence of a hiatal hernia. Concomitant hiatal hernia repair is recommended. To date, either medical therapy with proton pump inhibitors or conversion of LSG to laparoscopic Rouxen-Y gastric bypass are the available options for the management of GERD after LSG. Recently, new minimally invasive approaches have been proposed in patients with GERD and hypotensive LES: the LINX? Reflux Management System procedure and the Stretta? procedure. Large studies are needed to assess the safety and long-term efficacy of these new approaches. In conclusion, the recent publication of p H monitoring data and the new insights in the association between sleeve morphology and GERD control have led to a wider acceptance of LSG as bariatric procedure also in obese patients with GERD, as recently stated in the 5^(th) International Consensus Conference on sleeve gastrectomy. | Fabrizio Rebecchi Marco E Allaix Marco G Patti Francisco Schlottmann Mario Morino | 2017 | World Journal of Gastroenterology2017，23，13： | 4 |
| 2 | Optical coherence tomography analysis of the macula after scleral buckle surgery for retional detachment 显示文摘 | BENSON S E SCHLOTTMANN P G BUNCE C etal | 2007 | Ophthalmology2007，114，1： | 1 |
| 3 | S3-Leitlinie ?Exokrines Pankreaskarzinom” 2007显示文摘 | G Adler T Seufferlein S Bischoff H.-J Brambs S Feuerbach G Grabenbauer S Hahn V Heinemann W Hohenberger J Langrehr M Lutz O Micke H Neuhaus P Neuhaus H Oettle P Schlag R Schmid W Schmiegel K Schlottmann J Werner B Wiedenmann I Kopp | 2007 | Z Gastroenterol2007，，06： | 1 |
| 4 | Ultrasound-guided per- cutaneous endoscopic gastrostomy in patients with negative diapha- noscopy 显示文摘 | Schlottmann K Klebl F Wiest R | 2007 | Endoscopy2007，39，8： | 1 |
| 5 | Optical coherence tomography analysis of the macula after scleral buckle surgery for retinal detachment 显示文摘 | Benson SE Schlottmann PG Bunce C | 2007 | Ophthalmology2007，114，1： | 1 |
| 6 | Optical coherence tomography analysis of the macular after scleral buckle surgery for retinal detachment显示文摘 | Benson SE Schlottmann PG Bunce C | 2007 | Ophthalmology2007，114，1： | 1 |
| 7 | Expression of beta-defensin 1 and 2 in nasal epithelial cells and alveolar macrophages from HIV-infected patients显示文摘 | Alp S Skrygan M Schlottmann R | 2005 | Eur J Med Res2005，10，1： | 1 |
| 8 | Optical coherence tomography analysis of the macula after vitrectomy surgery for reti- nal detachment显示文摘 | Benson SE Schlottmann PG Bunce C | 2006 | Ophthalmology2006，113，7： | 1 |
| 9 | Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry显示文摘 | Schlottmann PG De Cilla S Greenfield DS | 2004 | Invest Ophthalmol Vis Sci2004，45，6： | 1 |
| 10 | Does migration matter? Job search outcomes for the unemployed 显示文摘 | Boehm T P Herzog HW Schlottmann A M | 1998 | Review of Regional Studies1998，，28： | 1 |
| 11 | Escherichia coli prevents phagocytosis - induced death of macrophages via classical NF - κB signaling, a link to T - cell activation 显示文摘 | Groesdonk HV Schlottmann S Richter F | 2006 | Infect Immun2006，74，10： | 1 |
| 12 | Analysis of the macula with optical coherence tomography after successful surgery for proliferative vitreoretinopathy 显示文摘 | Benson SE Grigoropoulos L Schlottmann PG | 2005 | Arch Ophthalmol2005，123，： | 1 |
| 13 | Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry显示文摘 | Schlottmann PG De Cilla S Greenfield DS | 2004 | Invest Ophthalmol Vis Sci2004，45，6： | 1 |
| 14 | The Wnt antag- onists DKKI and SFRP1 are downregulated by promoter hyperm- ethylation in systemic sclerosis显示文摘 | DEES C SCHLOTTMANN I FUNKE R | 2014 | Ann Rheum Dis2014，73，6： | 1 |
| 15 | Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry 显示文摘 | Schlottmann PG De Cilia S Greenfield DS | 2004 | Invest Ophthalmol Vis Sci2004，45，6： | 1 |
| 16 | Optical coheren- ce tomography analysis of the macula after vitrectomy surgery for retinal detachment 显示文摘 | Benson SE Schlottmann PG Bunce C | 2006 | Ophthalmology2006，113，： | 1 |
| 17 | Optical coherence tomography analysis of the macula after vitrectomy surgery for retinal detachments 显示文摘 | Benson SE Schlottmann PG Bunce C | 2006 | Ophthalmology2006，113，： | 1 |
| 18 | Optical coherence tomography analysis of the macula after scleral buckling surgery for retinal detachments 显示文摘 | Benson SE Schlottmann PG Bnnee C | 2007 | Ophthalmology2007，114，： | 1 |
| 19 | Predicting visual func- tion from the measurements of retinal nerve fiber layer structure 显示文摘 | Zhu H Crabb DP Schlottmann PG | 2010 | Invest Ophthalmol Vis Sci2010，51，56： | 1 |
| 20 | Optical coherence tomography analysis of the macula after vitrectomy surgery for retinal detachment显示文摘 | Benson SE Schlottmann PG Bunce C | | 0，，： | 1 |
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