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| 1 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013,12,5: | 7 |
| 2 | Chronic pancreatitis:a sequela of acute fatty liver of pregnancy显示文摘BACKGROUND: Chronic pancreatitis following acute fatty liver of pregnancy is rarely reported.METHODS: We treated a 34-year-old woman who developed acute fatty liver of pregnancy (AFLP) after delivery by caesarean section at 32 weeks of gestation. AFLP was complicated by acute pancreatitis and multiple organ failure. The management of the disease was primarily supportive. She recovered from acute fulminant liver failure and multi-organ failure, apart from the development of symptomatic chronic pancreatitis thereafter. RESULTS: Investigations failed to identify any other causes of chronic pancreatitis. The patient responded very well to pancreatic enzyme supplement for the treatment of steatorrhoea.CONCLUSION: To our knowledge, this is the first report of chronic pancreatitis as a consequence of multi-organ dysfunction caused by AFLP. | Wichian Apiratpracha Eric M.Yoshida Scudamore H.Charles Alan A.Weiss Michael F.Byrne | 2008 | Hepatobiliary & Pancreatic Diseases International2008,7,1: | 5 |
| 3 | Parvovirus B19 induced hepatic failure in an adult requiring liver transplantation显示文摘Parvovirus B19 induced acute hepatitis and hepatic failure have been previously reported, mainly in children. Very few cases of parvovirus induced hepatic failure have been reported in adults and fewer still have required liver transplantation. We report the case of a 55-year-old immunocompetent woman who developed fulminant hepatic failure after acute infection with Parvovirus B19 who subsequently underwent orthotopic liver transplantation. This is believed to be the first reported case in the literature in which an adult patient with fulminant hepatic failure associated with acute parvovirus B19 infection and without hematologic abnormalities has been identified prior to undergoing liver transplantation. This case suggests that Parvovirus B19 induced liver disease can affect adults, can occur in the absence of hematologic abnormalities and can be severe enough to require liver transplantation. | Darin S Krygier Urs P Steinbrecher Martin Petric Siegfried R Erb Stephen W Chung Charles H Scudamore Andrzej K Buczkowski Eric M Yoshida | 2009 | World Journal of Gastroenterology2009,15,32: | 3 |
| 4 | Technical report of a novel surgical technique: laparoscopic cyst fenestration and falciform ligament pedicle graft for treatment of symptomatic simple hepatic cysts显示文摘 | Faulds J M Scudamore C H | 2010 | Laparoendosc Adv Surg Tech A2010,20,10: | 1 |
| 5 | Cardiac troponin I in iso-proterenol-induced cardiac injury in the Hanover Wistar rat:stud-ies on low dose levels and routes of administration显示文摘 | Brady S York M Scudamore C | 2010 | ToxicologicPathology2010,38,2: | 1 |
| 6 | Occurrence and significance ofmycotoxins in forage crops and silage:a review显示文摘 | Scudamore K A Livesey C T | 1998 | Journal ofthe Science of Food and Agriculture1998,77,1: | 1 |
| 7 | Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatary T cells显示文摘 | Kohlhaas S Garden OA Scudamore C | 2009 | Immunol2009,182,5: | 1 |
| 8 | Transplantation:focus on kidney,liver and islet cells显示文摘 | Chang EN Scudamore CH Chung SW | 2004 | Can J Surg2004,47,2: | 1 |
| 9 | Carcass disposal: Lessons from Great Britain following the foot and mouth disease out- breaks of 2001 显示文摘 | Scudamore J M Trevelyan G M Tas M V | 2002 | Rev Sci Tech Off Int Epiz2002,21,3: | 1 |
| 10 | Radiofrequncy ablation of porcine liver in vivo:effects of blood flow and treatment time on lesion size显示文摘 | Patterson EJ Scudamore CH Owen DA | 1998 | Ann Surg1998,227,4: | 1 |
| 11 | Cutting edge:the Foxp3 target miRNA-155 contributes to the development of regulatory T cells显示文摘 | Kohlhaas S Garden O A Scudamore C | 2009 | J Immunol2009,182,5: | 1 |
| 12 | Radiofrequency ablation of porcine liver in vivo: elects of blood flow and treat- ment time on lesion size显示文摘 | Patterson EJ Scudamore CH Owen DA | 1998 | Ann Surg1998,227,4: | 1 |
| 13 | Characterizationof troponin response in a isoproterenol-induced cardiacinjury model in Hanover Wistar Rat显示文摘 | York MJ Scudamore C Brady S | 2007 | Toxicologic Pa-thology2007,35,4: | 1 |
| 14 | Frontal plane knee alignment:a cal for standardized measurement显示文摘 | Cooke TD Sled EA Scudamore RA | | 0,,09: | 1 |
| 15 | Multidisciplinary Management of Ruptured Hepatocellular Carcinoma显示文摘 | Andrzej K. Buczkowski Peter T.W. Kim Stephen G. Ho David F. Schaeffer Sung I. Lee David A. Owen Alan H. Weiss Stephen W. Chung Charles H. Scudamore | 2006 | Journal of Gastrointestinal Surgery2006,,3: | 1 |
| 16 | Radiofrequencyablation of porcine liver in vivo:effects of blood flow and treatmenttime on lesion size显示文摘 | Patterson EJ Scudamore CH Owen DA | 1998 | Ann Surg1998,227,4: | 1 |
| 17 | Hepatorenal Syndrome Associated with Obstructive Jaundice显示文摘 | Amin A. Nanji Charles H. Scudamore J Douglas Filipenko David A. Owen | 1985 | Journal of Clinical Gastroenterology1985,,5: | 1 |
| 18 | Survey for aflatoxins, ochratoxin A, zearalenone and fumonisins in maize imported into the United Kingdom 显示文摘 | SCUDAMORE K A PATEL S | 2000 | Food Addit Contam2000,17,5: | 1 |
| 19 | SEN virus infection in patients with hepatocellular carcinoma显示文摘 | MOMOSAKI S UMEMURA T SCUDAMORE C H | 2005 | J Viral Hepat2005,12,4: | 1 |
| 20 | Fate of fusarium mycotoxins in the cereal industry: recent UK studies显示文摘 | Scudamore KA | 2008 | World Mycotoxin Journal2008,1,: | 1 |