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| 1 | Long Campaign of BF with Overheating-Free Cooling Stave显示文摘A basic idea of permanent lining in designing long campaign of BF was put forward. BF designer should follow a chain of thinking procedure: Cooling water-Cooling system-Refractory lining. The temperature field of BF wall and cooling stave was calculated using heat transfer model and the results were proved by a 1 000-1 200 ℃ test rig. The overheating-free cooling stave with different parameters was designed, and such a long campaign of BF (15 years) was going to put into construction. | CHENG Su sen YANG Tian jun CANG Da qiang | 2003 | Journal of Iron and Steel Research(International)2003，10，3： | 7 |
| 2 | Late Paleozoic to Mesozoic extension in southwestern Fujian Province, South China: Geochemical, geochronological and Hf isotopic constraints from basic-intermediate dykes显示文摘The tectonic evolution of SE China block since late Paleozoic remains debated.Here we present a new set of zircon U-Pb geochronological,Lu-Hf isotopic data and whole-rock geochemistry for two stages of basicintermediate dykes from the southwestern Fujian.The samples were collected from the NE-trending(mainly diabases) and NW-trending(mainly diabasic diorites) dykes and yielded zircon U-Pb ages of 315 and 141 Ma,with ε_(Hf)(t) values of-8.90 to 7.49 and-23.39 to-7.15(corresponding to T_(DM2) values of 850 to 1890 Ma and 737 to 2670 Ma),respectively.Geochemically these rocks are characterized by low TiO_2(0.91-1.73 wt.%)and MgO(3.04-7.96 wt.%),and high Al_2O_3(12.5-16.60 wt.%) and K_2O(0.60-3.63 wt.%).Further they are enriched in LREEs and ULEs(Rb,Ba,Th and K).but depleted in HFSEs(Nb,Ta and Zr).The tectonic discrimination analysis revealed that the dykes were formed in an intraplate extensional environment.However,the NW trending dykes show crust-mantle mixed composition,which indicate an extensional tectonic setting with evidence for crustal contamination.The SE China block experienced two main stages of extensional tectonics from late Carboniferous to early Cretaceous.The tectonic evolution of the SE China block from late Devonian to Cretaceous is also evaluated. | Sen Wang Da Zhang Ganguo Wu Absai Vatuva Yongjun Di Pengcheng Yan Haibin Feng Shuai Ma | 2017 | Geoscience Frontiers2017，8，3： | 6 |
| 3 | Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction显示文摘During acute myocardial infarction,endoplasm ic reticulum(ER)stress-induced autophagy and apoptosis have been shown as im portant pathogeneses of myocardial reconstruction.Im portantly,hydrogen sulfide(H2S),as a third endogenous gas signaling molecule,exerts strong cytoprotective effect on anti-ER stress,autophagy regulation and antiapoptosis.Here,we showed that H2 S treatm ent inhibits apoptosis by regulating ER stress-autophagy axis and im proves myocardial reconstruction after acute myocardial infarction.We found that H2S intervention im proved left ventricle function,reduced glycogen deposition in myocardial tissue mesenchyme,and inhibited apoptosis.Moreover,the expressions of fibrosis indicators(Col3a1 and Col1a2),ER stress-related proteins(CHOP and BIP/ERP78),autophagy-related proteins(Beclin and ATG5),apoptosis protein(Bax),as well as fibrosis protein Col4a3bp were all decreased after treatm ent w ith H2 S.H2 S adm inistration also m aintained MMP/TIMP balance.Mechanistically,H2S activated the PI3K/AKT signaling pathway.In addition,H2S treatm ent also reduced the expressions of ER stress-related proteins,autophagy-related proteins,and apoptins in in wtro experiments.Interestingly,activation of ER stress-autophagy axis could reverse the inhibitory effect of H2S on myocardial apoptosis.Altogether,these results suggested that exogenous H2S suppresses myocardial apoptosis by blocking ER stress-autophagy axis,which in turn reverses cardiac rem odeling after myocardial infarction. | Yaling Li Maojun Liu Jiali Yi Xiong Song Xia Zheng Da Liu Sen Wang Chun Chu Jun Yang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，12： | 5 |
| 4 | Late Mesozoic Tectonic Evolution of Southwestern Fujian Province,South China:Constraints from Magnetic Fabric,Zircon U-Pb Geochronology and Structural Deformation显示文摘A combined study of magnetic fabrics, zircon U-Pb geochronology and structural deformation was carried out for Late Paleozoic sedimentary and Mesozoic magmatic rocks in the southwestern Fujian rift basin, South China, aiming at deciphering the tectonic evolution during Late Mesozoic. Field observations showed that the Late Mesozoic structure deformations in southwestern Fujian were categorized into four phases: NW-SE compression, ENE-WSW extension, NNE-SSW compression and NNW-SSE extension, sequentially. Zircons picked out from Juzhou granite and WNW-trending diabase dykes showed complete crystal shapes and clear oscillatory zonings on their edges, and the U-Pb dating yielded ages of 132 and 141 Ma, respectively. The susceptibility ellipsoid magnitude parameters of the Juzhou granite are characterized by flaser type strain ellipsoid, with pole density center of K3 falling into the first and the third quadrants, these features revealed that the Juzhou granite formed in ENE-WSW compressional stress field, indicating the early stage of Early Cretaceous extrusion in southwestern Fujian. The late stage of Early Cretaceous NNE-SSW extension was limited by the widespread WNW-trending diabase dykes, which were usually regarded as important indications for a regional extensional setting. On the basic of the previous researches, structural deformation studies, and the deductions above, it can be concluded that southwestern Fujian experienced five main tectonic stages during Late Mesozoic: Early Jurassic extension, Middle–Late Jurassic thrusting, early stage of Early Cretaceous extension, late stage of Early Cretaceous compression and Late Cretaceous extension. | Sen Wang Da Zhang Ganguo Wu Xingjian Li Xiaoqiao Gao Absai Vatuva Yuan Yuan Tengda Yu Yu Bai Ye Fang | 2018 | Journal of Earth Science2018，29，2： | 4 |
| 5 | New Geochronologic Evidence of Diabases and Their Metallogenic Relationship with the Makeng-Type Iron Deposits in Southwest Fujian, SE China显示文摘Objective The Makeng-type iron deposits are located in Late Paleozoic depression of southwest Fujian Province in the southeast edge of Cathaysia,which are famous for their huge scale and specific ore genesis.Previous studies mainly focus on the ore characteristics,metallogenic setting and the granites in the mining area,and there is still controversy on the ore genesis.Recent research | WANG Sen ZHANG Da WU Ganguo CAO Ke QU Hongjie MA Shuai YU Tengda | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 3 |
| 6 | An Investigation on the Molecular Characteristics and Intracellular Growth Ability among Environmental and Clinical Isolates of Legionella pneumophila in Sichuan Province, China显示文摘Objective To investigate the molecular characteristics and intracellular growth ability of Legionella pneumophila(L. pneumophila) strains from 1989 to 2016 in Sichuan Province, China. Methods Seventy-nine isolates of L. pneumophila were collected from environmental and clinical sources, including cooling towers, hot springs, bath water, fountains, and patients, and identified with 16 S rRNA gene analysis and serum agglutination assay. The isolates were then typed by Sequence-Based Typing(SBT), and Genotyping of forty-two LP1 strains were analyzed by means of multiple-locus VNTR analysis with 8 loci(MLVA-8). All strains were further analyzed for two virulence genes: Legionella vir homologue(lvh) and repeats in structural toxin(rtx A). The intracellular growth ability of 33 selected isolates was determined by examining their interaction with J774 cells. Results All isolates were identified to L. pneumophila including 11 serogroups, among which the main serogroup were LP1, accounting for 54.43%. Thirty-three different sequence types(STs) from five main clonal groups and five singletons were identified, along with 8 different MLVA patterns. Both the lvh and rtx A loci were found in all 79 strains. Thirty isolates showed high intracellular growth ability in J774 cells. Conclusion L. pneumophila is a potential threat to public health, and effective control and prevention strategies are urgently needed. | ZENG Lin Zi LIAO Hong Yu LUO Long Ze HE Shu Sen QIN Tian ZHOU Hai Jian LI Hong Xia CHEN Da Li CHEN Jian Ping | 2019 | Biomedical and Environmental Sciences2019，32，7： | 1 |
| 7 | Expression of hsp 90 in the human kidney and in proximal tubule cells exposed to heat, sodium arsenite and cadmium chloride 显示文摘 | Somji S Ann Sens M Garrett SH Gurel V Todd JH Sens DA | 2002 | Toxicol Lett2002，133，23： | 1 |
| 8 | A Study of the Key Techniques of High-Speed Optical Time Division Multiplexing Systems显示文摘 | LIU Xian bing directed by YE Pei da, ZHAO Zi sen | 2001 | The Journal of China Universities of Posts and Telecommunications2001，8，4： | 1 |
| 9 | Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells 显示文摘 | Dutta R Sens DA Somii S | 2002 | Prostate2002，52，2： | 1 |
| 10 | Antineutrophil cytoplasmic autoantibodies in systemic lupus erythematosus 显示文摘 | Sen D Isenberg DA | 2003 | Lupus2003，12，9： | 1 |
| 11 | Cadherin expression, vectorial active transport, and metallothionein isoform 3 mediated EMT/MET responses in cultured primary and immortalized human proximal tubule cells显示文摘 | Slusser A Bathula CS Sens DA | 2015 | PLoS One2015，10，12： | 1 |
| 12 | Metallothionein isoform 3expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells显示文摘 | Dutta R Sens DA Somji S | 2002 | Prostate2002，52，2： | 1 |
| 13 | A standardized grad- ing system for scleritis显示文摘 | Sen HN Sangave AA Goldstein DA | 2011 | Ophthahnology2011，118，： | 1 |
| 14 | Expression of hscT0, but not hsp70,inhuman third radar dental pulp显示文摘 | Sens DA McGuirt JP Khan W | 1997 | Eur J Oral Sci1997，105，3： | 1 |
| 15 | Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells显示文摘 | Dutta R Sens DA Somji S | 2002 | Prostate2002，52，2： | 1 |
| 16 | MiR‐142‐3p as a potential prognostic biomarker for esophageal squamous cell carcinoma显示文摘 | Rui‐Jun Lin Da‐Wei Xiao Lian‐Di Liao Tao Chen Ze‐Feng Xie Wei‐Zhe Huang Wei‐Sen Wang Tai‐Feng Jiang Bing‐Li Wu En‐Min Li Li‐Yan Xu | 2012 | J. Surg. Oncol2012，，2： | 1 |
| 17 | Expression of HSC70,but not hsp70, in human third molar dental pulp显示文摘 | Sens DA McGuirt JP Khan W | 1997 | Eur J Oral Sci1997，105，3： | 1 |
| 18 | Antineutrophil cytoplasmic autoantibodies in systemic lupus erythematosus 显示文摘 | Sen D Isenberg DA | 2003 | Lupus2003，12，9： | 1 |
| 19 | Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCI2显示文摘 | Somji S Sens DA Garrett SH | 1999 | Environ Health Perspect1999，107，7： | 1 |
| 20 | Metallothionein isoform 3 expres- sion inhibits cell growth and increases drug resistance of PC-3 pros- tate cancer cells显示文摘 | Dutta R Sens DA Sornji S | 2002 | Prostate2002，52，2： | 1 |
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