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| 1 | LEAFY HEAD2,which encodes a putative RNA-binding protein,regulates shoot development of rice显示文摘在植物的开发期间,更高的植物连续地在常规空间、时间的模式形成新叶子。有反常的叶的异种发展模式不仅提供大卓见进理解植物建筑学的规章的机制,而且充实方法到它庄稼产量能被改进的修正。这里,我们报导了米饭 leafy-head2 (lhd2 ) 的描述展览弄短的异种阶段的 plastochron,侏儒症,减少的 tiller 数字,和失败转移从对繁殖生长植物。而减少的 tiller 数字是 tiller 芽长出的抑制的后果,解剖、组织学的学习表明在 lhd2 的叶子的快速的出现从叶 primordia 的快速的开始被结果。分子、基因的分析证明 LHD2 与 67% 类似编码通常认为的 RNA 有约束力的蛋白质到玉米 TE1。染色体规模表示侧面在之间的比较野类型并且 lhd2 植物建议 LHD2 可以通过 KNOX 和荷尔蒙相关的基因调整米饭射击开发。LHD2 变化和 LHD2 的保存表示模式引起的类似的显型在在草控制时间的叶开始显示了保存机制。 | Guo Sheng Xiong Xing Ming Hu Yong Qing Jiao Yan Chun Yu Cheng Cai Chu Jia Yang Li Qian Qian Yong Hong Wang | 2006 | Cell Research2006，16，3： | 11 |
| 2 | Simultaneous preparation of TiO2 and ammonium alum,and microporous SiO2 during the mineral carbonation of titanium-bearing blast furnace slag显示文摘In this study,a route for simultaneous mineralization of CO2 and production of titanium dioxide and ammonium alum,and microporous silicon dioxide from titanium-bearing blast furnace slag(TBBF slag)was proposed,which is comprised of(NH4)2 S04 roasting,acid leaching,ammonium alum crystallization,silicic acid flocculation and Ti hydrolysis.The effects of relevant process parameters were systematically investigated.The re sults showed that under the optimal roasting and leaching conditions about 85%of titanium and 84.6%of aluminum could be extracted while only 30%of silicon entered the leachate.84%of Al^3+was crystallized from the leachate in the form of ammonium aluminum sulfate dodecahydrate with a purity up to 99.5 wt%.About 85%of the soluble silicic acid was flocculated with the aid of secondary alcohol polyoxyethylene ether 9(AEO-9)to yield a microporous SiO2 material(97.4 wt%)from the crystallized mother liquor.The Al-and Si-depleted solution was then hydrolyzed to generate a titanium dioxide(99.1 wt%)with uniform particle size distribution.It was figured out that approximately 146 kg TiO2 could be produced from 1000 kg of TBBF slag.Therefore,the improved process is a promising method for industrial application. | Yingjie Xiong Tahani Aldahri Weizao Liu Guanrun Chu Guoquan Zhang Dongmei Luo Hairong Yue Bin Liang Chun Li | 2020 | Chinese Journal of Chemical Engineering2020，28，9： | 7 |
| 3 | Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction显示文摘During acute myocardial infarction,endoplasm ic reticulum(ER)stress-induced autophagy and apoptosis have been shown as im portant pathogeneses of myocardial reconstruction.Im portantly,hydrogen sulfide(H2S),as a third endogenous gas signaling molecule,exerts strong cytoprotective effect on anti-ER stress,autophagy regulation and antiapoptosis.Here,we showed that H2 S treatm ent inhibits apoptosis by regulating ER stress-autophagy axis and im proves myocardial reconstruction after acute myocardial infarction.We found that H2S intervention im proved left ventricle function,reduced glycogen deposition in myocardial tissue mesenchyme,and inhibited apoptosis.Moreover,the expressions of fibrosis indicators(Col3a1 and Col1a2),ER stress-related proteins(CHOP and BIP/ERP78),autophagy-related proteins(Beclin and ATG5),apoptosis protein(Bax),as well as fibrosis protein Col4a3bp were all decreased after treatm ent w ith H2 S.H2 S adm inistration also m aintained MMP/TIMP balance.Mechanistically,H2S activated the PI3K/AKT signaling pathway.In addition,H2S treatm ent also reduced the expressions of ER stress-related proteins,autophagy-related proteins,and apoptins in in wtro experiments.Interestingly,activation of ER stress-autophagy axis could reverse the inhibitory effect of H2S on myocardial apoptosis.Altogether,these results suggested that exogenous H2S suppresses myocardial apoptosis by blocking ER stress-autophagy axis,which in turn reverses cardiac rem odeling after myocardial infarction. | Yaling Li Maojun Liu Jiali Yi Xiong Song Xia Zheng Da Liu Sen Wang Chun Chu Jun Yang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，12： | 5 |
| 4 | A high-resolution optically addressed spatial light modulator based on ZnO nanoparticles显示文摘An optically addressed spatial light modulator(OASLM)can modulate the wavefront of a read light by displaying a phase pattern or a hologram configured by the intensity distribution of a write light.Using ZnO nanoparticles(NPs)as a novel photoconductor,a high-resolution OASLM was fabricated.A ZnO NP suspension was spin-coated on an indium tin oxide(ITO)-coated glass substrate and annealed to form a photosensitive layer.The device was characterized electrically and optically.The device was operated at low driving voltages in the transmission mode.Updatable recording of a diffraction grating up to 825 lp mm^(-1) with a diffraction efficiency(DE)of 0.05%and binary holograms with pixel sizes from 2 mm down to 0.72 mm were demonstrated using a 405 nm wavelength write laser and a 635 nm wavelength read laser. | Pawan Kumar Shrestha Young Tea Chun Daping Chu | 2015 | Light(Science & Applications)2015，4，1： | 5 |
| 5 | Synthesis and Characterization of Sphere-like Pt Nanoparticles Supported on DWCNT/WO_3 Nanorods with Electrocatalytic Activity显示文摘Tungsten oxide(WO3) nanorods, which were used to load platinum(Pt) nanoparticles, were investigated. H2WO4 nanorods with diameters from 10 to 50 nm were obtained when tungsten precursor was added into homogenous double-walled carbon nanotubes(DWCNT) and ethylene glycol(EG) solution.Nanosized rod-like WO3 were achieved after calcination of the DWCNT/H2WO4 composite. Sphere-like Pt nanoparticles were loaded on the surface of the nanorods by EG in-situ reduction. Pt particles were isolated by DWCNT/WO3 nanorods and secondary accumulation could be prevented when Pt particles appeared in the DWCNT/WO3 nanorod/EG dispersion solution. Therefore, Pt nanoparticles with mean diameters of 2–6 nm could be obtained. Pt-deposited on DWCNT/WO3 nanorods exhibited high electrochemical activity, which could facilitate the low-cost mass production of Pt catalyst. | Yanhong Yin Chun'an Ma Ziping Wu Man Zhao Litao Chen Youqun Chu | 2015 | Journal of Materials Science & Technology2015，31，9： | 4 |
| 6 | Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice显示文摘 | Shou-cai ZHAO Chun WANG Heng XU Wen-qian WU Zhao-hu CHU Ling-song MA Ying-dong ZHANG Fudong LIU | 2017 | Acta Pharmacologica Sinica2017，38，11： | 4 |
| 7 | An Improved and Convenient Procedure for the Synthesis of Ozagrel显示文摘A novel approach to the synthesis of ozagrel is described. The target compound isconveniently prepared from the commercially available material, 1,1-carboxyldiimidazole (CDI)through the condensation and hydrolyzation. | Chun GUO Xiao Dan LIU Zhen Gang XIE Chu Jun LI | 2006 | Chinese Chemical Letters2006，17，2： | 3 |
| 8 | Decomposition and Reformulation of Banxia Baizhu Tianma Decoction:A Vasodilatory Approach显示文摘Objective To decompose and reformulate Banxia Baizhu Tianma Decoction(BBT) in order to optimize its ratio for vasodilatory effect.The fingerprints of these six component herbs were also studied via Tri-step FTIR analysis.Methods The herbal components of BBT were extracted separately with different solvents,such as 95%ethanol,50%ethanol,and distilled water.The vasodilatory effect of the extracts was studied using the in vitro pre-contracted aortic ring model.Among these extracts,the water extracts of Pinellia ternata[PT(W)]and Citri reticulatae[CR(W)],50%ethanol extracts of Castrodia elata[GE(50)]and Clycyrrhiza uralensis[GU(50)],and 95%ethanol extracts of Atractylodes macrocephala[AM(E)],and Poria cocos[PC(E)]were selected for the orthogonal stimulus-response compatibility group study due to their high effectiveness in vasodilation.Results The best combination ratio(G2) was GE(50),GU(50),AM(E),PC(E),CR(W),and PT(W) at EC_0,EC_5,EC_5,EC_5,EC_5,and EC_5,with EC_(50) of(0.06 ± 0.01) mg/mL.Comparison between the vasodilatory effects of extracts derived from G2 and BBT were also studied.From the results,the 50%ethanol extract following G2 ratio was found to be most potent extract with the highest vasodilatory effect compared with other extracts derived from G2 or BBT,with EC_(50) of(0.05 ±0.005) mg/mL.Conclusion The optimum ratio and appropriate extraction method for the new BBT formulae are obtained.G2 is determined as the best formulae with the highest potency in producing the vasodilatory effect on isolated rat aortic rings.The results obtained suggest that 50%ethanol is found to be the best solvent to extract the vasoactive compounds of G2 in order to exhibit the highest efficacy of vasodilatory effect. | Chu Shan Tan Yean Chun Loh Yung Sing Ch'ng Mariam Ahmad Mohd.Zaini Asmawi Mun Fei Yam | 2017 | Chinese Herbal Medicines2017，9，2： | 3 |
| 9 | Overview of one transistor type of hybrid organic ferroelectric non-volatile memory显示文摘Organic ferroelectric memory devices based on field effect transistors that can be configured between two stable states of on and off have been widely researched as the next generation data storage media in recent years.This emerging type of memory devices can lead to a new instrument system as a potential alternative to previous non-volatile memory building blocks in future processing units because of their numerous merits such as cost-effective process,simple structure and freedom in substrate choices.This bi-stable non-volatile memory device of information storage has been investigated using several organic or inorganic semiconductors with organic ferroelectric polymer materials.Recent progresses in this ferroelectric memory field,hybrid system have attracted a lot of attention due to their excellent device performance in comparison with that of all organic systems.In this paper,a general review of this type of ferroelectric non-volatile memory is provided,which include the device structure,organic ferroelectric materials,electrical characteristics and working principles.We also present some snapshots of our previous study on hybrid ferroelectric memories including our recent work based on zinc oxide nanowire channels. | Young Tea Chun Daping Chu | 2015 | Instrumentation2015，2，1： | 3 |
| 10 | MIT1, encoding a 15-cis-ζ-carotene isomerase, regulates tiller number and stature in rice显示文摘Lateral branching is an important determinant of shoot architecture and crop yield. The plant hormone strigolactone (SL) inhibits lateral bud outgrowth in various plant species. Deficiencies in SL biosynthesis and signal transduction result in excessive outgrowth of lateral buds (Stirnberg et al., 2002;Sorefan et al., 2003). | Lihua Liu Mengmeng Ren Peng Peng Yan Chun Lu Li Jinfeng Zhao Jingjing Fang Lixiang Peng Jijun Yan Jinfang Chu Yiqin Wang Shoujiang Yuan Xueyong Li | 2021 | Journal of Genetics and Genomics2021，48，1： | 3 |
| 11 | Ground-based Observations of Ultraviolet and Total Solar Radiation in Shenyang,Northeast China显示文摘Objective This work explores the diurnal variation of Solar ultraviolet radiation (UVR) and total solar radiation (TSR) in northeast China,using daily observations of UVR and TSR in Shenyang.Methods UVR and TSR measurements were carried out from March 1st,2006 to December 31st,2009 in Shenyang,Liaoning province,China (41°51' N,123°27' E).Results Both TSR and UVR showed seasonal variation,reaching the highest levels in summer and the lowest in winter.They showed the greatest fluctuation in summer and autumn.The irradiance of TSR and UVR on clear days around the equinoxes and solstices increased substantially compared with the mean seasonal irradiance,especially in autumn.The whole day accumulated dose of UVR in winter was far less than that during the middle part of a summer day (i.e.between 10:00 and 14:00).It was also less than the accumulated summer dose of morning and afternoon (i.e.between 8:00 and 10:00 and 14:00 and 16:00).Conclusion The instant irradiance and daily accumulated amount of UVR are low in Shenyang,especially in autumn and winter.Thus concern about the health effects arising because shortage of UVR in northeast China is warranted. | GAO Qian HU LiWen GONG HuiZhi GAO Na YU JiaMing WANG Yang CHU Chun YANG Hui LIU Yang | 2011 | Biomedical and Environmental Sciences2011，24，5： | 2 |
| 12 | Clinopyroxene and Fe-Ti oxides for correlating the ash from Changbaishan Millennium eruption显示文摘Volcanic glass compositions and tephra layer age are critical for anchoring their sources and correlating among different sites; however, such work may be imprecise when the tephra has varied compositions. The ash from Changbaishan Millennium eruption(940s AD), a widely distributed tephra layer, has been detected in the far-east areas of Russia, the Korean Peninsula, Japan, and in Greenland ice cores. There are some debates on the presence of this tephra from sedimentary archives to the west of Changbaishan volcano, such as lake and peat sediments in the Longgang volcanic field. In this paper, major element compositions for clinopyroxene and Fe-Ti oxides were performed on proximal tephra from Changbaishan and the Millennium eruption ash record in Lake Sihailongwan. Clinopyroxene and Fe-Ti oxides microlites from Sihailongwan show augite-ferroaugite and titanmagnetite compositions, similar to those from dark pumice in Changbaishan proximal tephra, but different from the light grey pumice, which has ferrohedenbergite and ilmenite microlite compositions. This result implies that the tephra recorded in Sihailongwan was mainly from the trachytic eruptive phase of the Millennium eruption, and the rhyolitic eruptive phase made a relatively small contribution to this area. Analyzing clinopyroxene and Fe-Ti oxides microlites is a new method for correlating tephra layers from Changbaishan Millennium eruption. | SUN Chun Qing LIU Jia Qi YOU Hai Tao CHU Guo Qiang | 2016 | Science China Earth Sciences2016，59，7： | 2 |
| 13 | Effect of surface ligand density on cytotoxicity and pharmacokinetic profile of docetaxel loaded liposomes显示文摘Various biotin-modified liposomes incorporated with docetaxel(DTX) were prepared to study the effect of surface biotin density on the pharmacokinetic profile of the liposome. Four types of liposomes such as PEG modified liposome(PDL), 0.5%(mol) biotin modified liposome(0.5 BDL), 1%(mol) biotin modified liposome(1 BDL) and 2%(mol) biotin modified liposome(2 BDL) were prepared using thin film dispersion method. The prepared liposomes were characterized by measuring encapsulation efficiency(EE), particle size, Zeta-potential, physical stability and drug release profiles in vitro. MTT assay was performed to elevate the cytotoxicity of liposomes on MCF-7 cells. In vivo evaluation was further performed to investigate the effect of biotin surface density on the pharmacokinetic profiles. All the prepared liposomes exhibited high encapsulation efficiency, small particle size, narrow particle distribution and sustained release profiles in vitro. In MTT assay, 0.5 BDL showed largest tumor cell toxicity, compared with DTX solution. All liposomes containing DTX showed prolonged blood circulation in vivo, and 0.5 BDL showed the longest circulation time among the biotin modified liposome. Surface modification of liposome had a negative impact on the circulation of liposomes in the blood, which needs to be considered when designing the ligand mediated targeting delivery systems. A proper amount of biotin liposome with 0.5% molar ratio is expected to produce the best anti-tumor effect. | Chun Chu Ping Xu Haoyue Zhao Qing Chen Dawei Chen Haiyang Hu Xiuli Zhao Mingxi Qiao | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，5： | 2 |
| 14 | A time- efficient pattern reduction algorithm for k-means clustering 显示文摘 | Ming Chaochiang Chun Weitsai Chu Singyang | 2011 | Information Sciences2011，181，4： | 1 |
| 15 | A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis显示文摘 | Haihai Liang Chun Zhang Tao Ban Yu Liu Liu Mei Xianmei Piao Dan Zhao Yanjie Lu Wenfeng Chu Baofeng Yang | 2012 | International Journal of Biochemistry and Cell Biology2012，，12： | 1 |
| 16 | Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging显示文摘 | Binh An P. Phan Baocheng Chu Nayak Polissar Thomas S. Hatsukami Chun Yuan Xue-Qiao Zhao | 2007 | The International Journal of Cardiovascular Imaging2007，，3： | 1 |
| 17 | Clinical presentations of patients from different age cohorts with biliary tract stone diseases显示文摘 | Kuang‐Chun Hu Horng‐Yuan Wang Wen‐Hsiung Chang Cheng‐Hsin Chu Shee‐Chan Lin Chun‐Jen Liu Ming‐Shiang Wu Shou‐Chuan Shih | 2014 | J Gastroenterol Hepatol2014，，8： | 1 |
| 18 | HBV genotype B is associated with better response to interferon therapy in HBeAg(+) chronic hepatitis than genotype C显示文摘 | Chun Tao Wai Chi-Jen Chu Munira Hussain Anna S.F. Lok | 2002 | Hepatology2002，，6： | 1 |
| 19 | Treatment response monitoring in patients with gastrointestinal stromal tumor using diffusion‐weighted imaging: preliminary results in comparison with positron emission tomography/computed tomography显示文摘 | Nan‐Jie Gong Chun‐Sing Wong Yiu‐Ching Chu Jing Gu | 2012 | NMR Biomed2012，，2： | 1 |
| 20 | Flower development of Phalaenopsis orchid involves functionally divergent SEPALLATA ‐like genes显示文摘 | Zhao‐Jun Pan You‐Yi Chen Jian‐Syun Du Yun‐Yu Chen Mei‐Chu Chung Wen‐Chieh Tsai Chun‐Neng Wang Hong‐Hwa Chen | 2014 | New Phytol2014，，： | 1 |
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