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| 1 | Thymoma and autoimmunity显示文摘The thymus is a central lymphatic organ that is responsible for many immunological functions,including the production of mature,functional T cells and the induction of self-tolerance.Benign or malignant tumors may originate from the thymus gland,with thymoma being the most common and accounting for 50% of anterior mediastinal tumors.Malignancies linked to thymoma include the loss of self-tolerance and the presence of autoimmunity.In this review,we compiled the current scientific evidence detailing the various interactions between thymoma and autoimmune diseases,including myasthenia gravis,systemic lupus erythematosus,inappropriate antidiuretic hormone secretion,pure red cell aplasia,pernicious anemia,pemphigus and autoimmune thyroid diseases.In recent years,several mechanisms have been proposed to explain these interactions.Most are based on the assumption that the‘sick’thymus,like the‘normal’thymus,can generate mature T cells;however,the T cells generated by the sick thymus are impaired and thus may exert cellular autoreactivity.Here,we present several theories that may shed light on the loss of self-tolerance associated with this epithelial tumor of the thymus. | Shahar Shelly Nancy Agmon-Levin Arie Altman Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011，8，3： | 19 |
| 2 | Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation显示文摘AIM: To determine effect of irritable bowel syndrome(IBS) subtype on IBS-specific quality of life(QOL) questionnaire and its subscales.METHODS: We studied IBS patients visiting our functional gastroenterology disorder clinic at a tertiary care center of Unites States.IBS and IBS subtype were diagnosed using Rome-Ⅲ questionnaire.QOL was assessed using IBS-QOL questionnaire.IBSQOL assesses quality of life along eight subscales: dysphoria,interference with activities,body image,health worry,food avoidance,social reactions,sexual health,and effect on relationships.IBS-QOL and its subscales were both scored on a range of 0-100 with higher scores suggestive of better QOL.Results of overall IBS-QOL scores and subscale scores are expressed as means with 95%CI.We compared mean IBS-QOL score and its subscales among various IBSsubtypes.Analysis of variance(ANOVA) was used to compare the mean difference between more than two groups after controlling for age and gender.A posthoc analysis using Bonferroni correction was used only when P value for ANOVA was less than 0.05.RESULTS: Of 542 patients screened,243 had IBS as per Rome-Ⅲ criteria.IBS-mixed(IBS-M) was the most common IBS subtype(121 patients,49.8%) followed by IBS- diarrhea(IBS-D)(56 patients,23.1%),IBSconstipation(IBS-C)(54 patients,22.2%) and IBSunspecified(IBS-U)(12 patients,4.9%).Overall IBSQOL scores were significantly different among various IBS-subtypes(P = 0.01).IBS-QOL of patients with IBS-D(61.6,95%CI: 54.0-69.1) and IBS-M(63.0,95%CI: 58.1-68.0) was significantly lower than patients with IBS-C(74.5,95%CI: 66.9-82.1)(P = 0.03 and 0.02 respectively).IBS-D patients scored significantly lower than IBS-C on food avoidance(45.0,95%CI: 34.8-55.2 vs 61.1,95%CI: 50.8-71.3,P = 0.04) and interference with activity(59.6,95%CI: 51.4-67.7 vs 82.3,95%CI: 74.1-90.6,P < 0.001).IBS-M patients had more interference in their activities(61.6,95%CI: 56.3-66.9 vs 82.3,95%CI: 74.1-90.6,P = 0.001) and greater impact on their relationships(73.3,95%CI: 68.4-78.2 vs 84.7,95%CI: 77.2-92.2,P = 0.02) than IBS-C patients.Patients with IBS-M also scored significantly lower than IBS-C on food avoidance(47.2,95%CI: 40.7-53.7 vs 61.1,95%CI: 50.8-71.3,P = 0.04) and social reaction(66.1,95%CI: 61.1-71.1 vs 80.0,95%CI: 72.1-87.7,P = 0.005).CONCLUSION: IBS-D and IBS-M patients have lower IBS-QOL than IBS-C patients.Clinicians should recognize food avoidance,effects on daily activities and relationship problems in these patients. | Prashant Singh Kyle Staller Kenneth Barshop Elaine Dai Jennifer Newman Sonia Yoon Shahar Castel Braden Kuo | 2015 | World Journal of Gastroenterology2015，21，26： | 9 |
| 3 | Derivatives of Meromorphic Functions with Multiple Zeros and Elliptic Functions显示文摘Let f be a nonconstant meromorphic function in the plane and h be a nonconstant elliptic function. We show that if all zeros of f are multiple except finitely many and T (r, h) = o{T (r, f )} as r →∞, then f' = h has infinitely many solutions (including poles). | Pai YANG Shahar NEVO | 2013 | Acta Mathematica Sinica,English Series2013，29，7： | 3 |
| 4 | Nanosphere molecularly imprinted polymers doped with gold nanoparticles for high selectivity molecular sensors显示文摘我们报导分子地使用的第一次尝试在为散布的提高的拉曼(重量的单位) 基于分子的种类察觉到的表面与金 nanoparticles (AuNPs ) 被做的 nanoparticles 的形状印了聚合物(MIP ) 。明确地,分子地做的 AuNPs 印了 nano 范围(AuNPs@nanoMIPs ) 被一个壶降水聚合为察觉到的 SERS 作为模板用苏丹 IV 综合。AuNPs@nanoMIPs 被扫描在 MIP 粒子内显示出 AuNPs 的准确地点的传播电子显微镜学(茎) 的各种各样的模式描绘。Au 集中和在形状和粒子的多分散性上激动人心的答案的效果被学习。仅仅当 MIP 粒子与 AuNPs 被做时,拉曼信号的重要改进被观察。重量的单位信号在 AuNPs@nanoMIPs 内随 Au 集中的增加显著地改善了。印的 AuNPs@nanoMIPs 与不同苏丹衍生物执行了的苏丹 IV 的选择大小显示出做 AuNPs 的 MIP 粒子的高选择。 | Tehila Shahar Tama Sicron Daniel Mandler | 2017 | Nano Research2017，10，3： | 3 |
| 5 | High-Q ring resonators directly written in As2S3 chalcogenide glass films显示文摘Planar ring resonator waveguides are fabricated in thin films of As2S3 chalcogenide glass,deposited on silicaon-silicon substrates.Waveguide cores are directly written by scanning the focused illumination of a femtosecond Ti:sapphire laser at a central wavelength of 810 nm,through a two-photon photo-darkening process.A large photoinduced index change of 0.3–0.4 refractive index units is obtained.The radius of the ring resonator is 1.9 mm,corresponding to a transmission free spectral range of 9.1 GHz.A high loaded(intrinsic) Q value of 110,000(180,000) is achieved.The thermal dependence of the resonator transfer function is characterized.The results provide the first report,to the best of our knowledge,of directly written high-Q ring resonators in chalcogenide glass films,and demonstrate the potential of this simple technique towards the fabrication of planar lightguide circuits in these materials. | Shahar Levy Matvei Klebanov Avi Zadok | 2015 | Photonics Research2015，3，3： | 3 |
| 6 | A Criterion of Normality Based on a Single Holomorphic Function显示文摘让 F 功能的一个家庭是领域 D 上的 holomorphic 吗? ?让 2 是的 k 一个整数和让的 h 是 D 上的 holomorphic 功能,所有谁的零至多有复合 k ? 1,以便 h (z) 有不普通零与任何 f F。也假设下列二个条件为每 f F 成立:(a) f (z)= 0?f (z)= h (z) ;并且(b) f (z)= h (z) ?| f (k)(z)|c,在 c 是一个常数的地方。当时, F 在 D 上是正常的。 | Xiao Jun LIU Shahar NEVO | 2011 | Acta Mathematica Sinica,English Series2011，27，1： | 2 |
| 7 | Ig G4-related disease manifesting as an acute gastric-pericardial fistula显示文摘Ig G4-related disease is a recently recognized entity linked initially to autoimmune pancreatitis and has been subsequently described in nearly every organ system. Men over the age of 50 represent the most affected demographic group and a comprehensive set of diagnostic criteria has been developed to aid treating clinicians. Though elevated levels of Ig G4 in the serum are suggestive of the disease, definitive diagnosis is made on histopathology. Treatment is tailored to the clinical presentation with corticosteroid therapy known to have proven efficacy. Gastric manifestations of the Ig G4-related disease primarily come in two varieties, notably chronic ulceration or pseudotumor formation. Autoimmune pancreatitis conveys increased risk for Ig G4-related disease of the stomach, which is independent of Helicobacter pylori status. In this case report, we present an acute gastric-pericardial fistula secondary to Ig G4-related disease that required urgent operative management. To our knowledge, this is the first report in the medical literature describing this complication of Ig G4-related disease. | James Frydman Shahar Grunner Yoram Kluger | 2014 | World Journal of Gastroenterology2014，20，44： | 2 |
| 8 | Application of iron oxide anoparticles in neuronal tissue engineering显示文摘Since the introduction of nanotechnology,nanoscale materials have developed rapidly and have been applied in various fields including in the pharmaceutical industry,medicine,and tissue engineering.Among a variety of nanomaterials,magnetic iron oxide nanoparticles(IONPs)have been intensively investigated for numerous in vivo applications such as gene and drug delivery,diagnostics,cell labeling and sorting.Compared to nanoparticles made from other ma- | Ofra Ziv-Polat Shlomo Margel Abraham Shahar | 2015 | Neural Regeneration Research2015，10，2： | 2 |
| 9 | Effects of long chain fatty acid unsaturation on the structure and controlled release properties of amylose complexes显示文摘 | Uri Lesmes Shahar H. Cohen Yizhak Shener Eyal Shimoni | 2008 | Food Hydrocolloids2008，，3： | 2 |
| 10 | Local Production of Lipoprotein-Associated Phospholipase A2 and Lysophosphatidylcholine in the Coronary Circulation: Association With Early Coronary Atherosclerosis and Endothelial Dysfunction in Humans显示文摘 | Shahar Lavi Joseph P. McConnell Charanjit S. Rihal Abhiram Prasad Verghese Mathew Lilach O. Lerman Amir Lerman | 2007 | Circulation2007，，21： | 2 |
| 11 | Keypoint based autonomous registration of terrestrial laser point-clouds显示文摘 | Shahar Barnea Sagi Filin | 2007 | ISPRS Journal of Photogrammetry and Remote Sensing2007，，1： | 2 |
| 12 | Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community based study显示文摘 | Nieto F J Young TB Lind BK Shahar E Samet JM Redline S D’ Agostino RB Newman AB Lebowitz MD Picketing TG | 2000 | JAMA2000，283，： | 1 |
| 13 | Intractable gelastic seizures during infancy: ictal positron emission tomography (PET) demonstrating epileptiform activity within the hypothalamic hamartoma 显示文摘 | Shahar E Goldsher D Genizi J | 2008 | J Child Neurol2008，23，： | 1 |
| 14 | Cardiogenic hepatorenal syndrome显示文摘 | Yeshurun D Shahar J | 1990 | Angiology1990，41，11： | 1 |
| 15 | Active vulnerability,adolescent distress,and the mediating/suppressing role of life events显示文摘 | Shahar G Priel B | 2003 | Personality and Individual Differences2003，35，： | 1 |
| 16 | Outcome of severe encephalomyelitis in children: effect of high-dose methylprednisone and immonuglobulins显示文摘 | Shahar E Andraus J Savitzki D | 2002 | J Child Neurol2002，17，： | 1 |
| 17 | Risk perception of driving as a function of advanced training aimed at recognizing and handling risks in demanding driving situations 显示文摘 | ROSENBLOObi T SHAHAR A ELHARAR A | 2008 | Accident Analysis and Prevention2008，40，2： | 1 |
| 18 | Effectiveness of a Combined Dance and Relaxation Intervention on Reducing Anxiety and Depression and Improving Quality of Life among the Cognitively Impaired Elderly显示文摘 | Adam D Ramli A Shahar S | 2016 | Sultan Qaboos University Medical Journal2016，16，1： | 1 |
| 19 | Effect of taurine on intestinal recovery following intestinal is- chemia-repeffusion injury in a rat 显示文摘 | Sukhotnik I Aranovich I Ben Shahar Y | 2016 | Pediatr Surg Int2016，32，2： | 1 |
| 20 | Absence seizures aggravated by valproie acid 显示文摘 | Lerman Sagie T Watemberg N Kramer U Shahar E Mermen P | 2001 | Epilepsia2001，42，7： | 1 |
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