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| 1 | Pancreatic fistula after pancreatectomy:Evolving definitions,preventive strategies and modern management显示文摘Pancreatic resection is the treatment of choice for pancreatic malignancy and certain benign pancreatic disorders. However, pancreatic resection is technically a demanding procedure and whereas mortality after a pancreaticoduodenectomy is currently < 3%-5% in experienced high-volume centers, post-operative morbidity is considerable, about 30%-50%. At present, the single most significant cause of morbidity and mortality after pancreatectomy is the development of pancreatic leakage and fistula (PF). The occurrence of a PF increases the length of hospital stay and the cost of treatment, requires additional investigations and procedures, and can result in life-threatening complications. There is no universally accepted definition of PF that would allow standardized reporting and proper comparison of outcomes between different centers. However, early recognition of a PF and prompt institution of appropriate treatment is critical to the prevention of potentially devastating consequences. The present article, reviews the evolution of post resection pancreatic fistula as a concept, and discusses evolving definitions, the current preventive strategies and the management of this problem. | Shailesh V Shrikhande Melroy A D'Souza | 2008 | World Journal of Gastroenterology2008，14，38： | 26 |
| 2 | Gastric floating ma- trix tablets: Design and optimization using combination of pol- ymers显示文摘 | Shailesh T Laxmanbhai D Dasharath M | 2008 | Acta Pharrn2008，58，： | 1 |
| 3 | Ad- vances in precipitated silicas for passenger and truck tyre treads显示文摘 | Okel Timothy A Patkar Shailesh D Bice Jo-Ann E | 1999 | Progress in Rubber and Plastics Technology1999，15，1： | 1 |
| 4 | 查看详情显示文摘 | Shailesh K D Rohit B Khanna A S | | 0，，： | 1 |
| 5 | Preparation and characteriza-tion of heat-resistant intel],enetrating polymer network(IPN)显示文摘 | Shailesh K D Palraj S Maruthan M S | 2007 | Progress in Organic Coatings2007，59，1： | 1 |
| 6 | Preparation and characterization of heat-resistant interpenetrating polymer network显示文摘 | Shailesh K D Palraj S Maruthan K | 2007 | Prog Org Coat2007，59，12： | 1 |
| 7 | Preparation and characteriza- tion of heat-resistant interpenetrating polymer network ( IPN ) 显示文摘 | Shailesh K D Palraj S Maruthan M S | 2007 | Progress in Organic Coatings2007，59，1： | 1 |
| 8 | Gamma prime coarsening and age-hardening behaviors in a new nickel base superalloy显示文摘 | Shuangqun Zhao Xishan Xie Gaylord D Smith Shailesh J Patel | 2004 | Materials Letters2004，，11： | 1 |
| 9 | Mechanism(s) of turmeric-mediated protective effects against benzo (a) pyrenederived DNA adducts 显示文摘 | Rachana T Shailesh D | 2002 | Cancer Letters2002，175，6： | 1 |
| 10 | Borderline resectable pancreatic tumors:Is there a need for further refinement of this stage?显示文摘BACKGROUND:The ideal treatment of patients with 'borderline resectable pancreatic tumors (BRTs)' needs to be established.Current protocols advise neoadjuvant chemo(radio)therapy,although some patients may appear to have BRT on preoperative imaging and a complete resection may be achieved without the need for vascular resection.The aim of the present study was to identify specific findings on preoperative imaging that could help predict in which patients with BRT a complete resection,with or without vascular resection (VR),could be achieved.METHODS:Twelve patients with BRTs were identified.Tumor location,maximum degree of circumferential contact (CC),length of contact of the tumor with major vessels (LC),and luminal narrowing of vessels at the point of contact with the tumor (venous deformity,VD) were graded on preoperatively acquired multidetector computed tomography (MDCT) images and then compared with the intraoperative findings and need for VR.RESULTS:A complete resection (R0) was achieved in 10 patients with 2 having microscopic positive margins (R1) on histopathology at the uncinate margin.Four of the 10 patients required VR (40%).In 3 of the 4 patients whose tumors required VRs,CC was ≥grade III and VD was grade 2.LC did not influence the need for VR.CONCLUSIONS:It is possible to achieve a complete resection at the first instance in patients found to have BRTs on preoperative imaging.Preoperative MDCT-based grading systems and our proposed criteria may help identify such patients,thus avoiding any delay in curative resections in such patients. | Shailesh V Shrikhande Supreeta Arya Savio George Barreto Sachin Ingle Melroy A D'Souza Rohini Hawaldar Parul J Shukla | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 0 |
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