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| 1 | Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction显示文摘To investigate the feasibility and time window of early detection of Wallerian degeneration in the corticospinal tract after middle cerebral artery infarction,23 patients were assessed using magnetic resonance diffusion tensor imaging at 3.0T within 14 days after the infarction.The fractional anisotropy values of the affected corticospinal tract began to decrease at 3 days after onset and decreased in all cases at 7 days.The diffusion coefficient remained unchanged.Experimental findings indicate that diffusion tensor imaging can detect the changes associated with Wallerian degeneration of the corticospinal tract as early as 3 days after cerebral infarction. | Ruiman Xie Min Fang Linjiang Zhou Shanghua Fan Jianying Liu Hongbo Quan Man Luo Dongying Qiu | 2012 | Neural Regeneration Research2012，7，12： | 20 |
| 2 | Effect of Trichoderma viride biofertilizer on ammonia volatilization from an alkaline soil in Northern China显示文摘Ammonia(NH3) volatilization is one of the primary pathways of nitrogen(N) loss from soils after chemical fertilizer is applied, especially from the alkaline soils in Northern China, which results in lower efficiency for chemical fertilizers. Therefore, we conducted an incubation experiment using an alkaline soil from Tianjin(p H 8.37–8.43) to evaluate the suppression effect of Trichoderma viride(T. viride) biofertilizer on NH3 volatilization, and compared the differences in microbial community structure among all samples. The results showed that viable T. viride biofertilizer(T) decreased NH_3 volatilization by 42.21% compared with conventional fertilizer((CK), urea), while nonviable T. viride biofertilizer(TS) decreased NH_3 volatilization by 32.42%. NH_3 volatilization was significantly higher in CK and sweet potato starch wastewater(SPSW) treatments during the peak period. T. viride biofertilizer also improved the transfer of ammonium from soil to sweet sorghum. Plant dry weights increased 91.23% and 61.08% for T and TS, respectively, compared to CK. Moreover, T. viride biofertilizer enhanced nitrification by increasing the abundance of ammonium-oxidizing archaea(AOA) and ammonium-oxidizing bacteria(AOB). The results of high-throughput sequencing indicated that the microbial community structure and composition were significantly changed by the application of T. viride biofertilizer. This study demonstrated the immense potential of T. viride biofertilizer in reducing NH_3 volatilization from alkaline soil and simultaneously improving the utilization of fertilizer N by sweet sorghum. | Xia Wang Shengjun Xu Shanghua Wu Shugeng Feng Zhihui Bai Guoqiang Zhuang Xuliang Zhuang | 2018 | Journal of Environmental Sciences2018，30，4： | 15 |
| 3 | Comparison on Soil Carbon Stocks Between Urban and Suburban Topsoil in Beijing, China显示文摘The urban population and urbanized land in China have both increased markedly since the 1980 s. Urban and suburban developments have grown at unprecedented rates with unknown consequences for ecosystem functions. In particular, the effect of rapid urbanization on the storage of soil carbon has not been studied extensively. In this study, we compared the soil carbon stocks of different land use types in Beijing Municipality. We collected 490 top-soil samples(top 20 cm) from urban and suburban sites within the Sixth Ring Road of Beijing, which cover approximately 2400 km2, and the densities of soil organic carbon(SOC), soil inorganic carbon(SIC), and total carbon(TC) were analyzed to determine the spatial distribution of urban and suburban soil carbon characteristics across seven land use types. The results revealed significant differences in soil carbon densities among land use types. Additionally, urban soil had significantly higher SOC and SIC densities than suburban soil did, and suburban shelterbelts and productive plantations had lower SIC densities than the other land use types. The comparison of coefficients of variance(CVs) showed that carbon content of urban topsoil had a lower variability than that of suburban topsoil. Further findings revealed that soil carbon storage increased with built-up age. Urban soil built up for more than 20 years had higher densities of SOC, SIC and TC than both urban soil with less than 10 years and suburban soil. Correlation analyses indicated the existence of a significantly negative correlation between the SOC, SIC, and TC densities of urban soil and the distance to the urban core, and the distance variable alone explained 23.3% of the variation of SIC density and 13.8% of the variation of TC density. These results indicate that SOC and SIC accumulate in the urban topsoil under green space as a result of the conversion of agricultural land to urban land due to the urbanization in Beijing. | LUO Shanghua MAO Qizheng MA Keming | 2014 | Chinese Geographical Science2014，24，5： | 8 |
| 4 | Quantitative Simulation on Soil Moisture Contents of Two Typical Vegetation Communities in Sanjiang Plain,China显示文摘Different types of vegetation occupy different geomorphology and water gradient environments in the San-jiang Plain,indicating that the soil moisture dynamics and water balance patterns of the different vegetation communi-ties might differ from each other.In this paper,a lowland system,perpendicular to the Nongjiang River in the Honghe National Nature Reserve(HNNR),was selected as the study area.The area was occupied by the non-wetland plant forest and the typical wetland plant meadow.The Microsoft Windows-based finite element analysis software package for simulating water,heat,and solute transport in variably saturated porous media(HYDRUS),which can quantita-tively simulate water,heat,and/or solute movement in variably-saturated porous media,was used to simulate soil moisture dynamics in the root zone(20-40 cm) of those two plant communities during the growing season in 2005.The simulation results for soil moisture were in a good agreement with measured data,with the coefficient of determi-nation(R2) of 0.44-0.69 and root mean square error(RMSE) ranging between 0.0291 cm3/cm3 and 0.0457 cm3/cm3,and index of agreement(d) being from 0.612 to 0.968.During the study period,the volumetric soil moisture content of meadow increased with the depth and its coefficient of variation decreased with the depth(from 20 cm to 40 cm),while under the forest the soil moisture content at different depths varied irregularly.The calculated result of water budget showed that the water budget deficit of the meadow was higher than that of the forest,suggesting that the meadow is more likely to suffer from water stress than the forest.The quantitative simulation by HYDRUS in this study did not take surface runoff and plant growth processes into account.Improved root water uptake and surface runoff models will be needed for higher accuracy in further researches. | LI Shanghua ZHOU Demin LUAN Zhaoqing PAN Yun JIAO Cuicui | 2011 | Chinese Geographical Science2011，21，6： | 7 |
| 5 | Role of Co Content on Densification and Microstructure of WC–Co Cemented Carbides Prepared by Selective Laser Melting显示文摘WC–Co cemented carbides, well-known as the conventional tooling materials, have not been successfully produced by one step additive manufacturing processes such as selective laser melting(SLM) yet. The microstructure evolution as well as WC grain growth behavior has rarely been investigated in detail during SLM process. In this study, the WC–Co cemented carbides with different Co contents(12–32 wt%) were prepared by optimized SLM processes for comparative investigation of densification behavior, microstructure characterization and mechanical property. The increase in Co content in feedstock carbide granules can improve the densification behavior during SLM process. The SLM processed WC-12 Co shows larger average WC grain size and higher percentage of coarser WC grains as compared with both WC-20 Co and WC-32 Co. The microstructure characterization, combined with finite element simulation, shows the WC grain growth mechanisms include agglomeration and dissolution-deposition of WC during SLM process and agglomeration of WC is an important mechanism especially for WC–Co cemented carbides with Co content as low as 12 wt%. The comparison between horizontal(perpendicular to the SLM laser beam) and vertical(parallel to the SLM laser beam) cross sections of carbides shows that SLM process introduces a certain degree of microstructure and mechanical behavior anisotropy for WC-12 Co, WC-20 Co, and WC-32 Co. | Jinyang Liu Jian Chen Li Zhou Bingyao Liu Yang Lu Shanghua Wu Xin Deng Zhongliang Lu Zhipeng Xie Wei Liu Jianye Liu Zhi Qu | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，9： | 5 |
| 6 | Effects of Earth's curvature and radial heterogeneity in dislocation studies:Case studies of the 2008 Wenchuan earthquake and the 2004 Sumatra earthquake显示文摘Recently,effects of Earth's curvature and radial heterogeneity on coseismic deformations are often investigated based on the 2004 Sumatra earthquake.However,such effects are strongly related to earthquake types.As a low dip angle event,the 2004 Sumatra earthquake is not a good seismic case for such a topic since the effects for moderate dip angle events are much bigger.In this study,the half-space and spherical dislocation theories are used,respectively,to calculate coseismic displacements caused by the 2008 Wenchuan earthquake and the 2004 Sumatra earthquake.Effects of Earth's curvature and stratification are investigated through the discrepancies of results calculated using the two dislocation theories.Results show that the effects of Earth's curvature and stratification for the 2008 Wenchuan earthquake are much larger than those for the 2004 Sumatra earthquake.Ignoring the effects will cause errors up to 100%-200% in far field displacements for a moderate dip angle event like the 2008 Wenchuan earthquake.Such great effects are much bigger than those conclusions of previous studies.Besides,comparison with observations verifies that spherical dislocation theories yield better results than half-space ones in far fields. | Guangyu Fu Wenke Sun Yoichi Fukuda Shanghua Gao Takashi Hasegawa | 2010 | Earthquake Science2010，23，4： | 4 |
| 7 | Spatial heterogeneity of urban soils:the case of the Beijing metropolitan region,China显示文摘Introduction:Urban soils are large pools of carbon,nitrogen,and other elements,supporting plant growth,sustaining biogeochemical cycles,and serving as the foundation for maintaining ecosystem function and services of urban green spaces(UGS).Quantifying urban soil properties is essential for assessing urban ecosystem services and detecting pollution.Characterizing spatial heterogeneity of urban soil properties,which may change with land use or urbanization,is crucial for understanding urban ecosystem functions.Methods:We collected 466 soil composite samples across the Beijing metropolitan region and then analyzed the heterogeneity of soil properties in UGS of Beijing metropolitan region by ANOVA along the urbanization gradient spanning different land uses.Results:Our results show that soil properties vary considerably among land-use types and along the urban-rural gradient.Soil moisture content,soil organic carbon(SOC),available phosphorus,available potassium,total nitrogen(TN),the ratio of SOC:TN(C/N),Pb,and Cu increased notably from suburbs to the urban core,while soil pH,bulk density,TN,Cr,Ni,and Mn were not significantly different across urbanization levels.Most soil properties,except soil TN,Cu,Cr,Ni,exhibited significant differences between different land uses.The highest levels of soil nutrients and heavy metals were found in roadsides and residential areas among all the land uses.Conclusions:The spatial heterogeneity of urban soils in the Beijing metropolitan region is mainly attributable to the different land uses.Soil nutrient content has increased in UGS due to fertilization and pollution.Contamination of urban soils by heavy metals is due largely to traffic emissions and pollution by industrial and household wastes.Although human activities tend to augment urban soil nutrient pools to maximize certain ecosystem services,they may inadvertently compromise these and other services by increasing pollution.Knowledge of urban soil spatial heterogeneity in UGS is indispensable for improving urban ecosystem management. | Qizheng Mao Ganlin Huang Alexander Buyantuev Jianguo Wu Shanghua Luo Keming Ma | 2014 | Ecological Processes2014，3，1： | 2 |
| 8 | Free involutive Hom-semigroups and Hom-associative algebras显示文摘当它的 unary 操作是趋于增加的并且是复杂物时,我们构造免费 Hom-semigroups。我们建设的方法由括的词。作为后果,我们获得一个集合为 unary 操作在一样的条件下面产生的免费 Hom 联合的代数学。 | Shanghua ZHENG Li GUO | 2016 | Frontiers of Mathematics in China2016，11，2： | 2 |
| 9 | Ecological selection of bacterial taxa with larger genome sizes in response to polycyclic aromatic hydrocarbons stress显示文摘Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous priority pollutants that cause great damage to the natural environment and health.Average genome size in a community is critical for shedding light on microbiome's functional response to pollution stress within an environment.Here,microcosms under different concentrations were performed to evaluate the selection of PAHs stress on the average genome size in a community.We found the distinct communities of significantly larger genome size with the increase of PAHs concentration gradients in soils,and consistent trends were discovered in soils at different latitudes.The abundance of Proteobacteria and Deinococcus-Thermus with relatively larger genomes increased along with PAHs stress and well adapted to polluted environments.In contrast,the abundance of Patescibacteria with a highly streamlined and smaller genome decreased,implying complex interactions between environmental selection and functional fitness resulted in bacteria with larger genomes becoming more abundant.Moreover,we confirmed the increased capacity for horizontal transfer of degrading genes between communities by showing an increased connection number per node positively related to the nid A gene along the concentration gradients in the co-occurrence network.Our findings suggest PAHs tend to select bacterial taxa with larger genome sizes,with significant consequences for community stability and potential biodegradation strategies. | Yuzhu Dong Shanghua Wu Haonan Fan Xianglong Li Yijing Li Shengjun Xu Zhihui Bai Xuliang Zhuang | 2022 | Journal of Environmental Sciences2022，34，2： | 2 |
| 10 | Effects of annealing and doping on nanostructured bismuth telluride thick films显示文摘 | LI Shanghua Hesham M A Soliman Jian Zhou | 2008 | Chemistry Materials2008，20，13： | 1 |
| 11 | High conversion efficiency of pristine TiO_2 nanotube arrays based dye-sensitized solar cells显示文摘We prepared highly-ordered titanium dioxide nanotube arrays (TNAs) by anodizing Ti foils in F-containing electrolytes.The crystalline nature and morphology of the TNAs were studied using X-ray diffraction patterns and scanning electron microscopy.We found the morphology of TNAs affects the light-to-electricity conversion efficiency (η) of dye-sensitized solar cells (DSSCs).The efficiency of DSSCs reached 5.95% under the condition of light illuminated from the counter electrode.The high efficiency of TNA-based DSSCs was attributed to the neat top surface of TNAs,which allows more dye molecule loading on the surface of the TiO 2 nanotubes,and fewer electron recombination centers and a low interface resistance of integrated TNAs. | WANG ShangHua TAN WeiWei ZHANG JingBo LIN Yuan | 2012 | Chinese Science Bulletin2012，57，8： | 1 |
| 12 | Preparation and characterization of anodic films on AZ31B Mg alloy formed in the silicate electrolytes with ethylene glycol oligomers as additives 显示文摘 | ZHU Feng WANG Jinwei LI Shanghua | 2012 | Applied Surface Sci- ence2012，258，： | 1 |
| 13 | Structure and raman spectroscopy of nanocrystalline TiO2 powder derived by sol-gel process显示文摘 | Zhou Qifa Wu Shanghua | 1997 | Chin Plays Lett1997，14，4： | 1 |
| 14 | Anaerobic degradation of xenobiotic organic contaminants(XOCs):The role of electron flow and potential enhancing strategies显示文摘In groundwater,deep soil layer,sediment,the widespread of xenobiotic organic contaminants(XOCs)have been leading to the concern of human health and eco-environment safety,which calls for a better understanding on the fate and remediation of XOCs in anoxic matrices.In the absence of oxygen,bacteria utilize various oxidized substances,e.g.nitrate,sulphate,metallic(hydr)oxides,humic substance,as terminal electron acceptors(TEAs)to fuel anaerobic XOCs degradation.Although there have been increasing anaerobic biodegradation studies focusing on species identification,degrading pathways,community dynamics,systematic reviews on the underlying mechanism of anaerobic contaminants removal from the perspective of electron flow are limited.In this review,we provide the insight on anaerobic biodegradation from electrons aspect-electron production,transport,and consumption.The mechanism of the coupling between TEAs reduction and pollutants degradation is deconstructed in the level of community,pure culture,and cellular biochemistry.Hereby,relevant strategies to promote anaerobic biodegradation are proposed for guiding to an efficient XOCs bioremediation. | Yijing Li Shanghua Wu Shijie Wang Shijie Zhao Xuliang Zhuang | 2021 | Journal of Environmental Sciences2021，33，3： | 1 |
| 15 | Biting:advancing front meets sphere packing显示文摘 | Li Xiangyang Teng Shanghua Ungor A | 2000 | International Journal for Numerical Methods in Engineering2000，49，12： | 1 |
| 16 | Nearly-linear time al- gorithms for preconditioning and solving symmetric, diago- nally dominant linear systems显示文摘 | SPIELMAN D A TENG Shanghua | 2014 | SIAM Journal on Matrix Analysis and Applications2014，35，3： | 1 |
| 17 | A coupled stress analysis of the steam generator tube considering the influence of the fluid flow and heat transfer in the primary and secondary sides显示文摘 | Baozhi Sun Lusong Zheng Longbin Yang Yanjun Li Jianxin Shi Shanghua Liu Hongliang Qi | 2015 | Applied Thermal Engineering2015，，： | 1 |
| 18 | Bulk synthesis of transparent and homogeneous polymeric hybrid materials with ZnO quantum dots and PMMA显示文摘 | Li Shanghua Toprak Muhammet S Jo Yun Suk | 2007 | Advanced Materials2007，19，24： | 1 |
| 19 | Effect of dual targeting procyanidins nanoparticles on metabolomics of lipopolysaccharide-stimulated inflammatory macrophages显示文摘Inflammation plays an important role in the occurrence and development of many inflammatory diseases.The purpose of this study was to evaluate the anti-inflammatory effect and metabolic behavior of the dual targeting procyanidins(PC)nanoparticles on lipopolysaccharide(LPS)-stimulated inflammatory macrophages by metabolomics method.The double-targeting PC nanoparticles could specifi cally target both the CD44 receptor and mitochondria,while the single targeting PC-loaded nanoparticles that could target the CD44 receptor on the surface of macrophages.The double-targeting PC nanoparticles had better inhibitory effect than single-targeting PC nanoparticles on the leakage of lactate dehydrogenase and reactive oxygen species overexpression induced by LPS.Amino acid metabolism,energy metabolism and purine metabolism were disordered in LPS-treated group,and metabolic pathway analysis indicated that the double-targeting PC nanoparticles reversed some of LPS impacts.The changes of these potential biomarkers and their corresponding pathways are helpful to further understand the mechanism of PC nanoparticles in alleviating inflammation,and promote their application in nutrition intervention. | Shanshan Tie Lijuan Zhang Bin Li Shanghua Xing Haitao Wang Yannan Chen Weina Cui Shaobin Gu Mingqian Tan | 2023 | Food Science and Human Wellness2023，12，6： | 1 |
| 20 | Metformin escape in prostate cancer by activating the PTGR1 transcriptional program through a novel super-enhancer显示文摘The therapeutic efficacy of metformin in prostate cancer(PCa)appears uncertain based on various clinical trials.Metformin treatment failure may be attributed to the high frequency of transcriptional dysregulation,which leads to drug resistance.However,the underlying mechanism is still unclear.In this study,we found evidences that metformin resistance in PCa cells may be linked to cell cycle reactivation.Super-enhancers(SEs),crucial regulatory elements,have been shown to be associated with drug resistance in various cancers.Our analysis of SEs in metformin-resistant(MetR)PCa cells revealed a correlation with Prostaglandin Reductase 1(PTGR1)expression,which was identified as significantly increased in a cluster of cells with metformin resistance through single-cell transcriptome sequencing.Our functional experiments showed that PTGR1 overexpression accelerated cell cycle progression by promoting progression from the G0/G1 to the S and G2/M phases,resulting in reduced sensitivity to metformin.Additionally,we identified key transcription factors that significantly increase PTGR1 expression,such as SRF and RUNX3,providing potential new targets to address metformin resistance in PCa.In conclusion,our study sheds new light on the cellular mechanism underlying metformin resistance and the regulation of the SE-TFs-PTGR1 axis,offering potential avenues to enhance metformin’s therapeutic efficacy in PCa. | Jianheng Ye Shanghua Cai Yuanfa Feng Jinchuang Li Zhiduan Cai Yulin Deng Ren Liu Xuejin Zhu Jianming Lu Yangjia Zhuo Yingke Liang Jianjiang Xie Yanqiong Zhang Huichan He Zhaodong Han Zhenyu Jia Weide Zhong | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
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