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您的检索式：作者名="Shaofei Niu"
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| 1 | Landscape Design of Urban Rail Transit Complex Based on the Concept of Sustainable Development显示文摘On the basis of current development of urban rail transit complex in China,this paper proposed that it is necessary to build a complete landscape design system of urban traffic complex.Combined with the concept of sustainable urban landscape design,this paper explored landscape design of urban rail transit complex from the macroscopic,mesocopic and microscopic perspective,and analyzed many design cases to provide references for the sustainable landscape design of urban rail transit complex in China. | NIU Shaofei SHEN Zhongwei | 2016 | Journal of Landscape Research2016，8，4： | 1 |
| 2 | Construction of multiple concentration gradients for single-cell level drug screening显示文摘Isolation and manipulation of single cells play a crucial role in drug screening.However,previously reported single-cell drug screening lacked multiple-dose concentration gradient studies,which limits their ability to predict drug performance accurately.To solve this problem,we constructed a multiconcentration gradient generator in which a Tai Chi-spiral mixer can accelerate solution mixing in a short time and produce a linear concentration gradient.Later,a gradient generator combined with a single-cell capture array was adopted to investigate the effects of single or combined doses of 5-fluorouracil and cisplatin on human hepatoma cells and human breast carcinoma cells(at the single-cell level).The results showed that both drugs were effective in inhibiting the growth of cancer cells,and the combination was more effective for human hepatoma cells.In addition,the relationship between the biomechanical heterogeneity(e.g.,deformability and size)of tumor cells and potential drug resistance at the single-cellevel was investigated,indicating that small and/or deformable cells were more resistant than large and/or less deformable cells.The device provides a simple and reliable platform for studying the optimal dosage of different drug candidates at the single-cell level and effectively screening single-agent chemotherapy regimens and combination therapies. | Shaofei Shen Fangjuan Zhang Yali Zhang Yi Li Yanbing Niu Long Pang Jinyi Wang | 2023 | Microsystems & Nanoengineering2023，9，2： | 0 |
| 3 | Measuring the built environment of green transit-oriented development:A factorcluster analysis of rail station areas in Singapore显示文摘Green transit-oriented development(TOD)is an evolution of the TOD theory,influenced by sustainable development and green urbanism.This advancement expands the environmental and ecological dimensions of conventional TOD.However,relevant research has only just started,particularly in combination with high-density cities in Asia.This study measures the built environment of Green TOD and identifies the key factors and characteristics of the Green TOD built environment.An evaluation method for the Green TOD built environment is developed on the basis of the 5D(density,diversity,design,destination,and distance)built environment framework and combined with green urbanism theories.Data from 23 rail station areas in Singapore were collected and analyzed using factor and cluster analysis.Five factors,namely,neighborhood spatial form factor,facility completeness factor,open space factor,high-density mixed land-use factor,and walking amenity factor,are extracted.Twentythree station areas are classified into five clusters.The characteristics and optimization strategies of each cluster are analyzed on the basis of the statistical and graphical analyses.This research displays the characteristics and typology of the Green TOD built environment in an empirical way and offers a foundation for further research in diverse urban contexts. | Shaofei Niu Ang Hu Zhongwei Shen Ying Huang Yanchuan Mou | 2021 | Frontiers of Architectural Research2021，10，3： | 0 |
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