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54篇 您的检索式:作者名="Shaohua Lu"
    题名 作者 年代 出处 被引量
1Dynamics of vehicle-pavement coupled system based on a revised flexible roller contact tire model显示文摘A revised flexible roller contact tire model (RFRC tire model) is proposed, which considers not only the geometric and flexible filtering effect, but also tire damping and pavement displacement. A vehi- cle-pavement coupled system is modeled as a two DOF oscillator moving along a simply supported beam on a linear viscoelastic foundation. By using the Galerkin’s and Direct Integral method, dynamical responses of the vehicle-pavement coupled system are obtained based on the RFRC tire model and the traditional single point contact tire model (SPC tire model). The simulation results are compared with test data and the validity of the proposed RFRC tire model is verified. Differences between the two models are also investigated. It is found that the dynamical behaviors for both models agree with each other quite well when road surface roughness is a long harmonic wave. On the other hand, they are different under short harmonic wave or impulse road excitation. Thus the RFRC tire model should be used to compute the tire force and investigate dynamical responses of vehicle and pavement.YANG ShaoPu LI ShaoHua LU YongJie 2009Science China(Technological Sciences)2009,52,3:13
2Species composition and distribution of marine nematode community in the North Taiwan Strait显示文摘Marine free-living nematodes were investigated at 13 sampling stations divided into three transects in the northern Taiwan Strait in February 1998. One hundred species of marine nematodes belonging to 91 Genera 28 Families 3 Orders were identified and were first recorded in the northern Taiwan Strait. The dominant species were Vasostoma sp., Sabatieria sp. 1, Linhystera sp. 1, Spilophorella sp., Daptonema sp., Halalaimus sp. and Dorylaimopsis variabilis. Their main densities were all over 4 950 ind./m2. According to mean density at transects, marine nematode density decreased from coastal Weitou to off Minjiang Estuary, which was similar to polychaete distribution in northern Taiwan Strait. The selective deposit feeder (1A) was the dominant food type of marine nematodes in the northern Taiwan Strait, but non-selective deposit feeders (1B) and epigrowth feeders (2A) occupied high proportion, indicating diverse feeding types of marine nematodes in the northern Taiwan Strait. Some environmental factors such as currents are discussed.Cai Lizhe, Hong Huasheng, Zou Chaozhong, Fang Shaohua, Lu Xiaomei, Zhang Yueping (1. Key Laboratory of SEDC of Marine Environmental Science/Environmental Science Research Center, Xiamen Universi- ty, Xiamen 361005, China 2. Department of Biology, Xiamen 2001Acta Oceanologica Sinica2001,20,2:12
3Higher PD-1 expression concurrent with exhausted CD8+ T cells in patients with de novo acute myeloid leukemia显示文摘Objective: To investigate the association between the T cell inhibitory receptor programmed death 1(PD-1)and T cell exhaustion status in T cells from patients with de novo acute myeloid leukemia(AML) and AML in complete remission(CR).Methods:Surface expression of PD-1 and the exhaustion and immunosenescence markers CD244 and CD57 on CD3+,CD4+ and CD8+ T cells from peripheral blood samples from 20 newly diagnosed,untreated AML patients and 10 cases with AML in CR was analyzed by flow cytometry.Twenty-three healthy individuals served as control.Results:A significantly higher percentage of PD-1+ cells were found for CD3+ T cells in the de novo AML group compared with healthy controls.In addition,an increased level of PD-1+ CD8+ T cells,but not PD-1+ CD4+,was found for CD3+ T cells in the de novo AML and AML-CR samples.A higher percentage of CD244+ CD4+,CD244+ CD8+,CD57+ CD4+ and CD57+ CD8+ T cells was found in CD3+ T cells in samples from those with de novo AML compared with those from healthy controls.Strong increased PD-1+ CD244+ and PD-1+ CD57+ coexpression was found for CD4+ and CD8+ T cells in the de novo AML group compared with healthy controls.Conclusions:We characterized the major T cell defects,including co-expression of PD-1 and CD244,CD57-exhausted T cells in patients with de novo AML,and found a particular influence on CD8+ T cells,suggesting a poor anti-leukemia immune response in these patients.Jiaxiong Tan Shaohua Chen Yuhong Lu Danlin Yao Ling Xu Yikai Zhang Lijian Yang Jie Chen Jing Lai Zhi Yu Kanger Zhu Yangqiu Li 2017Chinese Journal of Cancer Research2017,29,5:10
4Research on dynamics of a class of heavy vehicle-tire-road coupling system显示文摘The dynamic tire force of heavy vehicle is a primary reason for road damage. This paper presents a mathematic model to restore the interacting process of vehicle-tire-road system and tries to find out the mechanics of interaction. A nonlinear tri-axle vehicle model with IBS (integral balanced suspension) is firstly proposed based on the detailed analysis of structural features of a heavy vehicle (DFL1250). The results indicate that the nonlinearities in the vehicle suspension contribute to improvement of ride comfort and to the reduction of dynamic tire force. Furthermore, an FRC (flexible rolling contact) tire model with the enveloping characteristics is added into the IBS model. The tire model considers both the tire contact history with rough road profile and the uneven distribution characteristics of vertical load. The FRC model is able to remove medium and high vibration components from uneven road profile due to its filtering feature. It is expected that these results could supply a new idea for vehicle-road interaction research.LU YongJie YANG ShaoPu LI ShaoHua 2011Science China(Technological Sciences)2011,54,8:6
5Validation and target gene screening of hsa-miR-205 in lung squamous cell carcinoma显示文摘Huang Wei Jin Yi Yuan Yunfeng Bai Chunxue Wu Ying Zhu Hongguang Lu Shaohua 2014Chinese Medical Journal2014,,2:6
6Understanding the proteome encoded by “non-coding RNAs”:new insights into human genome显示文摘A great number of non-coding RNAs(ncRNAs) account for the majority of the genome. The translation of these ncRNAs has been noted but seriously underestimated due to both technological and theoretical limitations. Based on the development of ribosome profiling(Ribo-seq), full length translating RNA analysis(RNC-seq) and mass spectrometry technology, more and more ncRNAs are being found to be translated in different organism, and some of them can produce functional peptides. While recently, not only individual new functional proteins, but also a new proteome have been experimentally discovered to be encoded by endogenous lncRNAs and circRNAs. These new proteins are of biological significance, suggesting the connection of the translation of ncRNAs to human physiology and diseases. Therefore, an in-depth and systematic understanding of the coding capabilities of ncRNAs is necessary for basic biology and medicine. In this review, we summarize the advances in the field of discovering this new proteome, i.e. 'ncRNA-coded' proteins.Shaohua Lu Tong Wang Gong Zhang Qing-Yu He 2020Science China(Life Sciences)2020,63,7:5
7Theoretical analysis of polarization properties for tilted fiber Bragg gratings显示文摘The polarization properties for tilted fiber Bragg gratings (TFBGs) are investigated theoretically based on coupled-mode theory and Mueller matrix method. The expression of wavelength-related polarizationdependent loss (PDL) for TFBGs with different tilt angles is derived and calculated. Simulation results are compared, and the results indicate that the polarization capability of TFBGs with 45° angle is stronger than other TFBGs with smaller angles. The degree of polarization for unpolarized light passing TFBGs is also simulated to further evaluate the polarization properties for various tilt angles. In addition, the relationship between physical parameters of a TFBG and its polarization capability is discussed.XU OU LU ShaoHua JIAN ShuiSheng 2010Science China(Information Sciences)2010,53,2:5
8Spatial-temporal Evolution Characteristics and Decoupling Analysis of Influencing Factors of China’s Aviation Carbon Emissions显示文摘The aviation industry has become one of the top ten greenhouse gas emission industries in the world. China’s aviation carbon emissions continue to increase, but the analysis of its influencing factors at the provincial level is still incomplete. This paper firstly uses Stochastic Impacts by Regression on Population, Affluence and Technology model(STIRPAT) model to analyze the time series evolution of China’s aviation carbon emissions from 2000 to 2019. Secondly, it uses the Logarithmic Mean Divisia Index(LDMI) model to analyze the influencing characteristics and degree of four factors on China’s aviation carbon emissions, which are air transportation revenue, aviation route structure, air transportation intensity and aviation energy intensity. Thirdly, it determines the various factors’ influencing direction and evolution trend of 31 provinces’ aviation carbon emissions in China(not including Hong Kong, Macao, Taiwan of China due to incomplete data). Finally, it derives the decoupling effort model and analyzes the decoupling relationship and decoupling effort degree between air carbon emissions and air transportation revenue in different provinces. The study found that from 2000 to2019, China’s total aviation carbon emissions continued to grow, while the growth rate of aviation carbon emissions showed a fluctuating downward trend. Air transportation revenue and aviation route structure promote the growth of total aviation carbon emissions, and air transportation intensity and aviation energy intensity have a restraining effect on the growth of total aviation carbon emissions. The scope of negative driving effect of air transportation revenue and air transportation intensity on total aviation carbon emissions in various provinces has increased. While the scope of positive driving influence of aviation route structure on total aviation carbon emissions of various provinces has increased, aviation energy intensity mainly has negative driving influence on total aviation carbon emissions of each province. Overall, the emission reduction trend in the areas to the west and north of the Qinling-Huaihe River Line is obvious. The decoupling mode between air carbon emissions and air transportation revenue in 31 provinces is mainly expansion negative decoupling.The air transportation intensity effect shows strong decoupling efforts in most provinces, the decoupling effort of aviation route structure effect and aviation energy intensity effect is not prominent.HAN Ruiling LI Lingling ZHANG Xiaoyan LU Zi ZHU Shaohua 2022Chinese Geographical Science2022,32,2:5
9Influence of vehicle-road coupled vibration on tire adhesion based on nonlinear foundation显示文摘The influence of pavement vibration on tire adhesion is of great significance to the structure design of vehicle and pavement.The adhesion between tire and road is the key to studying vehicle dynamics,and the precise description of tire adhesion affects the accuracy of dynamic vehicle responses.However,in most models,only road roughness is considered,and the pavement vibration caused by vehicle-road interaction is ignored.In this paper,a vehicle is simplified as a spring-mass-damper oscillator,and the vehicle-pavement system is modeled as a vehicle moving along an Euler-Bernoulli beam with finite length on a nonlinear foundation.The road roughness is considered as a sine wave,and the shear stress is ignored on the pavement.According to the contact form between tire and road,the LuGre tire model is established to calculate the tire adhesion force.The Galerkin method is used to simplify the partial differential equations of beam vibration into finite ordinary differential equations.A product-to-sum formula and a Dirac delt function are used to deal with the nonlinear term caused by the nonlinear foundation,which realizes the fast and accurate calculation of super-high dimensional nonlinear ordinary differential equations.In addition,the dynamic responses between the coupled system and the traditional uncoupled system are compared with each other.The obtained results provide an important theoretical basis for research on the influence of vehicle-road coupled vibration on tire adhesion.Junning ZHANG Shaopu YANG Shaohua LI Yongjie LU Hu DING 2021Applied Mathematics and Mechanics(English Edition)2021,42,5:4
10Interface structure prediction via CALYPSO method显示文摘The atomistic structures of solid–solid interfaces are of fundamental interests for understanding physical properties of interfacial materials. However, determination of interface structures faces a substantial challenge, both experimentally and theoretically. Here, we propose an efficient method for predicting interface structures via the generalization of our in-house developed CALYPSO method for structure prediction. We devised a lattice match toolkit that allows us to automatically search for the optimal latticematched superlattice for construction of the interface structures. In addition, bonding constraints(e.g.,constraints on interatomic distances and coordination numbers of atoms) are imposed to generate better starting interface structures by taking advantages of the known bonding environment derived from the stable bulk phases. The interface structures evolve by following interfacially confined swarm intelligence algorithm, which is known to be efficient for exploration of potential energy surface. The method was validated by correctly predicting a number of known interface structures with only given information of two parent solids. The application of the developed method leads to prediction of two unknown grain boundary(GB) structures(r-GB and p-GB) of rutile TiO_2 ∑5(2 1 0) under an O reducing atmosphere that contained Ti^(3+)as the result of O defects. Further calculations revealed that the intrinsic band gap of p-GB is reduced to 0.7 eV owing to substantial broadening of the Ti-3 d interfacial levels from Ti^(3+)centers.Our results demonstrated that introduction of grain boundaries is an effective strategy to engineer the electronic properties and thus enhance the visible-light photoactivity of TiO_2.Bo Gao Pengyue Gao Shaohua Lu Jian Lv Yanchao Wang Yanming Ma 2019Science Bulletin2019,64,5:4
11High speed cutting of AZ31 magnesium alloy显示文摘Using LBR-370 numerical control lathe,high speed cutting was applied to AZ31 magnesium alloy.The influence of cutting parameters on microstructure,surface roughness and machining hardening were investigated by using the methods of single factor and orthogonal experiment.The results show that the cutting parameters have an important effect on microstructure,surface roughness and machine hardening.The depth of stress layer,roughness and hardening present a declining tendency with the increase of the cutting speed and also increase with the augment of the cutting depth and feed rate.Moreover,we established a prediction model of the roughness,which has an important guidance on actual machining process of magnesium alloy.Liwei Lu Shaohua Hu Longfei Liu Zhenru Yin 2016Journal of Magnesium and Alloys2016,4,2:2
12A mobile polar atmospheric parameter measurement system:Ⅱ. First atmospheric turbulence observation at Antarctic Taishan Station显示文摘This is the second paper of a series devoted to atmospheric optical turbulence C2 n observation using a mobile polar atmospheric parameter measurement system. We present the initial results of C2 n measurement at Antarctic Taishan Station using micro-thermal sensors and a three-dimensional sonic anemometer at height ~2.0 m above the snow surface. The site testing experiments were carried out during the 30 th Chinese National Antarctic Research Expedition(CHINARE). We collected about 1 000 h of data between 30 December 2013 and 10 February 2014. The C2 n curve exhibits clear daily structures, with two peaks around midnight and midday and two troughs around 7:30 and 17:00 local time(UTC+5). The mean C2 n is 2.7×10-15 m-2/3 and the 25 th and 75 th percentiles of the C215 n cumulative distribution are 9.6×10-16 m-2/3 and 6.2×10- m-2/3, respectively. Meteorological parameters such as temperature, relative humidity, wind speed, and air pressure are also presented.TIAN Qiguo JIANG Peng WU Xiaoqing JIN Xinmiao LU Shan JI Tuo CHAI Bo ZHANG Shaohua ZHOU Hongyan 2015Advances in Polar Science2015,26,2:2
13Synthesis and performance of carbon-modified LiFePO_4 using an in situ PVA pyrolysis procedure显示文摘LiFePO4/carbon composite cathode material was prepared by granulating and subsequent pyrolysis processing in N2 at- mosphere with polyvinyl alcohol (PVA) as the carbon source. The influences of carbon content on the microstructure and battery performance were investigated. Single LiFePO4 phase and amorphous carbon can be found in the products. A special mi- cro-morphology of the optimum sample was observed. The discharge capacity of the cell with the optimum cathode was 135 mAh·g?1, close to the charge capacity of 153 mAh·g?1 at 17 mA·g?1. The influence of ambient temperature on the cell capacity was investigated. The temperature dependence of its electrochemical characteristic was evaluated by using AC impedance spectroscopy. A new equivalent circuit based on the charge and mass transfer control process in an electrode was proposed to fit the obtained AC im- pedance spectra. The tendency of every element in the equivalent circuit was used to interpret the temperature dependence of the ca- pacity of the optimum cathode.Shaohua Luo Zilong Tang Junbiao Lu Linfeng Hu Zhongtai Zhang 2007Journal of University of Science and Technology Beijing2007,14,6:2
14Transarterial infusion chemotherapy with FOLFOX for advanced hepatocellular carcinoma:a multi-center propensity score matched analysis of real-world practice显示文摘Background:To compare the treatment effectiveness and safety among transarterial infusion chemotherapy(TAI)with FOLFOX regimen,transarterial chemoembolization(TACE),and sorafenib in patients with BCLC stage C hepatocellular carcinoma(HCC).Methods:The data of consecutive patients with BCLC stage C HCC treated with TAI,TACE,or sorafenib from January 2015 to December 2018 at three centers were retrospectively analyzed.Propensity-score matched(PSM)analysis was pairwise performed to reduce selection bias.Treatment effectiveness and safety were evaluated and compared using the Kaplan-Meier method,log-rank test,Cox regression models,andχ2 test.Results:The median overall survival(OS)in the matched TAI cohort was significantly longer than the sorafenib cohort(19.6 vs.7.5 months,P=0.009),and the TACE cohort(estimated 27.8 vs.6.6 months,P<0.001).The difference in median progression-free survival(PFS)between the matched TAI and sorafenib cohorts was not significant(5.8 vs.2.3 months,P=0.219).The median PFS in the matched TAI cohort was significantly longer than the TACE cohort(6.5 vs.2.8 months,P<0.001).The objective response rate(ORR)in the matched TAI cohort was significantly higher than the sorafenib cohort(36.4%vs.0.0%,P<0.001)and the TACE cohort(48.7%vs.4.7%,P<0.001).The incidences of adverse events(AEs)were similar among these three cohorts.Conclusions:TAI with FOLFOX regimen was an effective and safe therapy that improved survival of patients with BCLC stage C HCC.Shaohua Li Jie Mei Qiaoxuan Wang Feng Shi Hongyan Liu Ming Zhao Lianghe Lu Yihong Ling Zhixing Guo Yabing Guo Xiaoming Chen Ming Shi Wan Yee Lau Wei Wei Rongping Guo 2021Hepatobiliary Surgery and Nutrition2021,10,5:2
15UMBRELLA: user demand privacy preserving framework based on association rules and differential privacy in social networks显示文摘Dear editor,The past several years have witnessed that people deeply rely on online services,such as shopping,transportation,and medical services.At the same time,privacy leakage has been a hot topic in social networks[1,2].Morever,the increasing applications of location based services(LBSs)indeed make our lives more convenient.However,LBSs also lead to significant privacy leakage.On the one hand,location information of a single point is sensitive.On the other hand,location trajec.tories can excavate more sensitive information despite location.In this regard,location privacy-preserving mechanisms have been extensively studied,such as Dunmiy,spatial confusion[3,4],encryption technology[5,6],differential privacy(DP)[7,8]and references therein.Chunliu YAN Ziyi NI Bin CAO Rongxing LU Shaohua WU Qinyu ZHANG 2019Science China(Information Sciences)2019,62,3:2
16Switchable du- M-wavelength erbium-doped fiber-ring laser based on one polarization maintaining fiber Bragg grating in a Sagnac loop interferometer 显示文摘Feng Suchun Xu Ou Lu Shaohua 2009Optics & Laser Technology2009,41,:1
17A durable Ni/La-Y catalyst for efficient hydrogenation of γ-valerolactone into pentanoic biofuels显示文摘Zeolite-supported metal catalysts containing hydrogenation centers and acid sites are promising in the chemoselective hydrogenation of biomass platform molecules into value-added chemicals and fuels.The primary challenge of employing such bifunctional catalysts for biomass conversion lies in catalyst stability in the liquid phase under harsh conditions. Herein, we have prepared a Ni/La-Y nanocatalyst via an improved wet impregnation method. Compared with Ni nanoparticles on H-Y, La addition shows a significantly enhanced stability and performance in the continuous liquid-phase hydrogenation of γ-valerolactone(GVL) into ethyl pentanoate(EP) at 200 ℃ for 1000 h. Complementary characterization studies reveal that La addition in the metal/zeolite catalyst not only efficiently modulates the acid property of the zeolite to alleviate coke formation, but also suppresses zeolite dealumination and metal agglomeration and leaching upon catalysis over a 1000 h period. These findings provide an efficient approach for improving the stability of zeolite-supported bifunctional catalysts, leading to potential application in hydrogen-assisted biomass valorization under the liquid-phase conditions.Jiang He Lu Lin Meng Liu Caixia Miao Zhijie Wu Rui Chen Shaohua Chen Tiehong Chen Yang Su Tao Zhang Wenhao Luo 2022Journal of Energy Chemistry2022,31,7:1
18Preparation and characterization of some surface negatively charged residue mutants of cytochrome b_5显示文摘Site-directed mutagenesis was used to obtain seven variants of tryptic fragment of bovine liver cytochrome bs (cyt bs), in which the negatively charged residues around the heme exposed edge of cyt bs were replaced by hydropho-bic amino acid alanine. Double-site mutants, triple-site mutants and even quadruple-site mutants were obtained. DNA sequencing and molecular weight measurements of the mutant proteins both confirmed that these site-directed muta-genesises were successfully performed. Spectroelectrochem-istry of these mutant proteins revealed that the apparent redox potentials of these mutant proteins caused a positive shift of 2-10 mV. The global structure of these mutant proteins did not show much difference from that of the wild type cyt bs, providing a solid base for the further study on the roles of the proteins’ surface charges.WANG Yunhua, WANG Wenhu, LU Junxia, REN Yi, GU Shaohua, XIE Yi & HUANG Zhongxian1. Chemical Biology Lab, Department of Chemistry, Fudan University, Shanghai 200433, China 2. Genetic Institute, School of Life, Fudan University, Shanghai 200433, China 2001Chinese Science Bulletin2001,46,7:1
19Single-polarization, switchable dual wavelength erbium-doped fiber laser with two polarization maintaining fiber Bragg gratings显示文摘Feng Suncbun Xu Ou Lu Shaohua 2008OptEapress2008,16,11:1
20AC con- ductors' corona loss calculation and analysis显示文摘LU Fangcheng YOU Shaohua LIU Yunpeng 2012IEEE Trans- actions on Power Delivery2012,27,2:1
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