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| 1 | Identification of herbal medicinal materials using DNA barcodes显示文摘Herbal medicinal materials have been used worldwide for centuries to maintain health and to treat disease.However,adulteration of herbal medicines remains a major concern of users and industry for reasons of safety and efficacy.Identification of herbal medicinal materials by DNA technology has been widely applied,started from the mid-1990s.In recent years,DNA barcoding of global plant species using four standard barcodes(rbcL,matK,trnH-psbA and ITS) has been a major focus in the fields of biodiversity and conservation.These DNA barcodes can also be used as reliable tools to facilitate the identification of herbal medicinal materials for the safe use of herbs,quality control,and forensic investigation.Many studies have applied these DNA barcodes for the identification of herbal medicinal species and their adulterants.The present article reviews efforts in the identification of herbal medicinal materials using the standard DNA barcodes and other DNA sequence-based markers. | Ming LI Hui CAO Paul Pui-Hay BUT Pang-Chui SHAW | 2011 | Journal of Systematics and Evolution2011，49，3： | 33 |
| 2 | Trends of Extreme Precipitation in Eastern China and Their Possible Causes显示文摘Significant increases of heavy precipitation and decreases of light precipitation have been reported over widespread regions of the globe. Global warming and effects of anthropogenic aerosols have both been proposed as possible causes of these changes. We examine data from urban and rural meteorological stations in eastern China(1955–2011) and compare them with Global Precipitation Climatology Project(GPCP) data(1979–2007) and reanalysis data in various latitude zones to study changes in precipitation extremes. Significant decreases in light precipitation and increases in heavy precipitation are found at both rural and urban stations, as well as low latitudes over the ocean, while total precipitation shows little change.Characteristics of these changes and changes in the equatorial zone and other latitudes suggest that global warming rather than aerosol effects is the primary cause of the changes. In eastern China, increases of annual total dry days(28 days) and 10 consecutive dry days(36%) are due to the decrease in light precipitation days, thereby establishing a causal link among global warming, changes in precipitation extremes, and higher meteorological risk of floods and droughts. Further, results derived from the GPCP data and reanalysis data suggest that the causal link exists over widespread regions of the globe. | LIU Run LIU Shaw Chen Ralph J.CICERONE SHIU Chein-Jung LI Jun WANG Jingli ZHANG Yuanhang | 2015 | Advances in Atmospheric Sciences2015，32，8： | 19 |
| 3 | Removal of formaldehyde over Mn_xCe_(1- x)O_2 catalysts: Thermal catalytic oxidation versus ozone catalytic oxidation显示文摘MnxCe1-xO2(x:0.3–0.9)prepared by Pechini method was used as a catalyst for the thermal catalytic oxidation of formaldehyde(HCHO).At x=0.3 and 0.5,most of the manganese was incorporated in the fluorite structure of Ce O2to form a solid solution.The catalytic activity was best at x=0.5,at which the temperature of 100%removal rate is the lowest(270°C).The temperature for 100%removal of HCHO oxidation is reduced by approximately 40°C by loading 5 wt.%Cu Oxinto Mn0.5Ce0.5O2.With ozone catalytic oxidation,HCHO(61 ppm)in gas stream was completely oxidized by adding 506 ppm O3over Mn0.5Ce0.5O2catalyst with a GHSV(gas hourly space velocity)of 10,000 hr-1at 25°C.The effect of the molar ratio of O3to HCHO was also investigated.As O3/HCHO ratio was increased from 3 to 8,the removal efficiency of HCHO was increased from 83.3%to 100%.With O3/HCHO ratio of 8,the mineralization efficiency of HCHO to CO2was 86.1%.At 25°C,the p-type oxide semiconductor(Mn0.5Ce0.5O2)exhibited an excellent ozone decomposition efficiency of 99.2%,which significantly exceeded that of n-type oxide semiconductors such as Ti O2,which had a low ozone decomposition efficiency(9.81%).At a GHSV of 10,000 hr-1,[O3]/[HCHO]=3 and temperature of 25°C,a high HCHO removal efficiency(≥81.2%)was maintained throughout the durability test of 80 hr,indicating the long-term stability of the catalyst for HCHO removal. | Jia Wei Li Kuan Lun Pan Sheng Jen Yu Shaw Yi Yan Moo Been Chang | 2014 | Journal of Environmental Sciences2014，26，12： | 9 |
| 4 | Prospective study of scoring system in selective intraoperative cholangiography during laparoscopic cholecystectomy显示文摘AIM: To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC).METHODS: The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its predictive value in choledocholithiasis.RESULTS: The scoring system was developed in a retrospective study of 264 cases, the statistical analyses showed the predictive factors included sex, transaminase levels, alkaline phosphatase level, bilirubin level, and common bile duct diameter on ultrasonography. The scoring system was used in 184 cases prospectively, of which, 3 of 162 (1.9%) cases scoring <3 had choledocholithiasis, 17 of 22 (77.3 %) cases scores≥3 had choledocholithiasis. A case of scores≥3 or more prospectively should be considered highly intraoperative cholangiography during laparoscopic cholecystectomy.CONCLUSION: The scoring system can predict choledocholithiasis and is helpful in selection patietns for intraoperative cholangiography. | Xiao-Dong Sun Xiao-Yan Cai Jun-Da Li Xiu-Jun Cai Yi-Ping Mu Jin-Min Wu Department of General Surgery,The Affiliated Sir Run Run Shaw Hospital,Zhejiang University Medical College,Hangzhou 310016,Zhejiang Province,China | 2003 | World Journal of Gastroenterology2003，9，4： | 7 |
| 5 | What about people in pedestrian navigation?显示文摘Pedestrian navigation has become an important theoretical and practical research topic in many disciplines such as cartography,geographical information science,global and indoor positioning,spatial behavior,psychology,sociology,and neuroscience.Many research studies view pedestrian navigation using process-oriented and goal-directed approaches.However,this paper revisits people’s needs in pedestrian navigation and classifies their needs as three layers:physical sense layer,physiological safety layer,and mental satisfaction layer according to Maslow’s theory.This paper introduces a people-centric framework for pedestrian navigation theory based on these three layers and discusses theoretical challenges for meeting each layer of people’s needs.These challenging theories may represent promising and valuable research and promote usage of pedestrian navigation systems or devices in the future. | Zhixiang FANG Qingquan LI Shih-Lung SHAW | 2015 | Geo-Spatial Information Science2015，18，4： | 4 |
| 6 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 7 | High Elevation Energy and Water Balance:the Roles of Surface Albedo and Temperature显示文摘Observation and modeling of the coupled energy and water balance is the key to understand hydrospheric and cryospheric processes at high elevation.The paper summarizes the progress to address this aspect in relation with different earth system elements,from glaciers to wetlands.The energy budget of two glaciers,i.e.Xiao Dongkemadi and Parlung No.4,was studied by means of extended field measurements and a distributed model of the coupled energy and mass balance was developed and evaluated.The need for accurate characterization of surface albedo was further documented for the entire Qinghai Tibet Plateau by numerical experiments with Weather Research and Forecast(WRF)on the sensitivity of the atmospheric boundary layer to the parameterization of land surface processes.A new approach to the calibration of a coupled distributed watershed model of the energy and water balance was demonstrated by a case study on the Heihe River Basin in northwestern China.The assimilation of land surface temperature did lead to the retrieval of critical soil and vegetation properties as the soil permeability and the canopy resistance to the exchange of vapour and carbon dioxide.The retrievals of actual Evapo-Transpiration(ET)were generated by the ETMonitor system and evaluated against eddy covariance measurements at sites spread throughout Asia.As regards glacier response to climate variability,the combined findings based on satellite data and model experiments showed that the spatial variability of surface albedo and temperature is significant and controls both glacier mass balance and flow.Experiments with both atmospheric and hydrosphere-cryosphere models documented the need and advantages of using accurate retrievals of land surface albedo to capture lan-atmosphere interactions at high elevation. | Massimo MENENTI Li JIA Marco MANCINI Xin LI Francesca PELLICCIOTTI Kun YANG Jiancheng SHI Maria Jose ESCORIHUELA Chiara CORBARI Shaoting REN Chunfeng MA Chaolei ZHENG Lian LIU Thomas SHAW Baohong DING Wei YANG | 2020 | Journal of Geodesy and Geoinformation Science2020，3，4： | 3 |
| 8 | Trends of Regional Precipitation and Their Control Mechanisms during 1979–2013显示文摘Trends in precipitation are critical to water resources. Considerable uncertainty remains concerning the trends of regional precipitation in response to global warming and their controlling mechanisms. Here, we use an interannual difference method to derive trends of regional precipitation from GPCP(Global Precipitation Climatology Project) data and MERRA(ModernEra Retrospective Analysis for Research and Applications) reanalysis in the near-global domain of 60?S–60?N during a major global warming period of 1979–2013. We find that trends of regional annual precipitation are primarily driven by changes in the top 30% heavy precipitation events, which in turn are controlled by changes in precipitable water in response to global warming, i.e., by thermodynamic processes. Significant drying trends are found in most parts of the U.S. and eastern Canada,the Middle East, and eastern South America, while significant increases in precipitation occur in northern Australia, southern Africa, western India and western China. In addition, as the climate warms there are extensive enhancements and expansions of the three major tropical precipitation centers–the Maritime Continent, Central America, and tropical Africa–leading to the observed widening of Hadley cells and a significant strengthening of the global hydrological cycle. | Run LIU Shaw Chen LIU Chein-Jung SHIU Jun LI Yuanhang ZHANG | 2016 | Advances in Atmospheric Sciences2016，33，2： | 3 |
| 9 | Factors influencing the results of treatment of bile duct injuries during laparoscopic cholecystectomy显示文摘BACKGROUND: The short-term results of repair of lapa- roscopic bile duct injuries have been well discussed, but the long-term results have been rarely reported. This study was undertaken to evaluate the factors influencing the outcome of repair of bile duct injuries caused by laparoscopic chole- cystectomy. METHODS: The outcomes of repair of bile duct injuries caused by laparoscopic cholecystectomy in 31 patients were reviewed retrospectively, and the effects of injury recogni- tion, cholangiography, repair modality and techniques on the long-term results were analyzed. RESULTS: Bile duct injuries were repaired successfully in 19 (95%) of 20 patients with injuries who had been recog- nized intraoperatively, and in 10 (90%) of 11 patients with injuries who had been recognized postoperatively. Repair was successful in 29 (93% ) of the 31 patients after complete cholangiography. Closure of partial division, laceration, or small perforation of the bile duct with or without T tube drainage was satisfactory in the 23 patients. End to end re- pair over T tube was successful in 2 transection patients, who were detected intraoperatively. Roux-en-Y hepatico- jejunostomy was used successfully to repair transection, ex- cision or stricture of the bile duct in 4 of 5 patients (80% ). CONCLUSION: Early detection of bile duct injuries caused by laparoscopy, complete evaluation of the biliary duct, and appropriate surgical modality and techniques are help- ful to improve the results of repair for laparoscopic bile duct injuries. | Li-Bo Li, Xiu-Jun Cai, Yi-Ping Mou, Qi Wei and Xian-Fa Wang Hangzhou, China Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University Medical College, Hangzhou 310016, China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，1： | 2 |
| 10 | AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice显示文摘 | Yu Li Shanqin Xu Maria M. Mihaylova Bin Zheng Xiuyun Hou Bingbing Jiang Ogyi Park Zhijun Luo Etienne Lefai John Y.-J. Shyy Bin Gao Michel Wierzbicki Tony J. Verbeuren Reuben J. Shaw Richard A. Cohen Mengwei Zang | 2011 | Cell Metabolism2011，，4： | 2 |
| 11 | TBK1-medicated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis显示文摘Mitochondrial dynamics,including mitochondrial fission and fusion,are critical for maintaining mitochondrial functions.Evidence shows that TANK-binding kinase 1(TBK1)regulates mitochondrial fusion and fission and then mitophagy.Since a previous study demonstrates a strong correlation between mitophagy and osteoarthritis(OA),we herein investigated the potential role of TBK1 in OA process and mitochondrial functions.We demonstrated a strong correlation between TBK1 and OA,evidenced by significantly downregulated expression of TBK1 in cartilage tissue samples of OA patients and in the chondrocytes of aged mice,as well as TNF-α-stimulated phosphorylation of TBK1 in primary mouse chondrocytes.TBK1 overexpression significantly attenuated TNF-α-induced apoptosis and abnormal mitochondrial function in primary mouse chondrocytes.Furthermore,TBK1 overexpression induced remodeling of mitochondrial morphology by directly phosphorylating dynamin-related protein 1(DRP1)at Ser637,abolishing the fission of DRP1 and preventing its fragmentation function.Moreover,TBK1 recruitment and DRP1 phosphorylation at Ser637 was necessary for engulfing damaged mitochondria by autophagosomal membranes during mitophagy.Moreover,we demonstrated that APMK/ULK1 signaling contributed to TBK1 activation.In OA mouse models established by surgical destabilization of the medial meniscus,intraarticular injection of lentivirus-TBK1 significantly ameliorated cartilage degradation via regulation of autophagy and alleviation of cell apoptosis.In conclusion,our results suggest that the TBK1/DRP1 pathway is involved in OA and pharmacological targeting of the TBK1-DRP1 cascade provides prospective therapeutic benefits for the treatment of OA. | Sun-li Hu Abdullah Al Mamun Jian Shaw Sun-long Li Yi-feng Shi Xue-man Jin Ying-xin Yu Chao-zhi Pang Ze-yang Li Jia-jie Lu Yue-piao Cai Xiang-yang Wang Jian Xiao | 2023 | Acta Pharmacologica Sinica2023，44，3： | 2 |
| 12 | Spatiotemporal analysis of critical transportation links based on time geographic concepts: a case study of critical bridges in Wuhan, China显示文摘 | Zhixiang Fang Shih-Lung Shaw Wei Tu Qingquan Li Yuguang Li | 2012 | Journal of Transport Geography2012，，： | 2 |
| 13 | Response to Comments by Yuan WANG on “Trends of Extreme Precipitation in Eastern China and Their Possible Causes”显示文摘In his comments,Wang cites a number of works to dispute the conclusion in our previous work,which attributes the observed decreases/increases in light/heavy precipitation in eastern China primarily to global warming rather than the regional aerosol effect. However,most of the cited works(admittedly,including our previous work),employ correlation analysis,which has little bearing on the cause–effect relationship. Theoretical analyses and/or modeling studies are needed to ascertain the cause–effect relationship. We argue that theoretical analyses and modeling results show that global warming is the primary cause of the widely observed phenomena of suppression of light precipitation and enhancement of heavy precipitation across the globe,including in eastern China. | LIU Run LIU Shaw Chen Ralph J.CICERONE SHIU Chein-Jung LI Jun WANG Jingli ZHANG Yuanhang | 2015 | Advances in Atmospheric Sciences2015，32，10： | 2 |
| 14 | A strategic analysis of inter organizational information sharing显示文摘 | LI Jingquan SIKORA Riyaz SHAW J Michael | 2006 | Decision support systems2006，42，1： | 1 |
| 15 | A space–time efficiency model for optimizing intra-intersection vehicle–pedestrian evacuation movements显示文摘 | Zhixiang Fang Qiuping Li Qingquan Li Lee D. Han Shih-Lung Shaw | 2013 | Transportation Research Part C2013，，： | 1 |
| 16 | Oil Sensitivity and Systematic Risk in Oil-sensitive Stock Indices 显示文摘 | Shaw Kat Hammoudeh and Li Huimin 2005 | 2005 | Journal of Economics and Business2005，，57： | 1 |
| 17 | n-Times integrated C-semigroups and the abstract Cauchy problem显示文摘 | Li Yuanchuan Shaw Senyen | 1997 | Taiwanese J Math1997，1，1： | 1 |
| 18 | Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential显示文摘 | Jiao L Y Ouyang S Y Liang M F Niu F F Shaw N Wu W Ding W Jin C Peng Y Zhu Y P Zhang F S Wang T Li C Zuo X B Luan C H Li D X Liu Z J | 2013 | J Virol2013，87，12： | 1 |
| 19 | Endothelial progenitor dysfunction in the pathogenesis of diabetic retinopathy:treatment concept to correct diabetes-associated deficits显示文摘 | Li Calzi S Neu MB Shaw LC | 2010 | EPMA J2010，1，1： | 1 |
| 20 | Comparison and fusion of multiresolution features for texture clarification显示文摘 | LI S T SHAWE TAYLOR J | 2005 | Pattern Recognition Letters2005，26，5： | 1 |
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