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| 1 | MicroRNA expression and function in prostate cancer: a review of current knowledge and opportunities for discovery显示文摘MicroRNAs (miRNAs ) 是广泛地通过编码基因的 posttranscriptional silencing 调整基因表示的保存得好的 noncoding RNA。在前列腺和另外的癌症的 Dysregulated miRNA 表示含有他们在癌症的角色生物学。而且,功能的研究在癌症开始和前进为对几条关键小径的 miRNAs 的贡献提供支持。miRNA 基因表示在之间的比较分析恶意并且 nonmalignant 前列腺纸巾,健康控制和前列腺癌症(PCa ) 病人,以及好攻击的更少对更好攻击的疾病显示 miRNAs 可以是未来在肿瘤组织,血,或尿的诊断或预示的 biomarkers。进一步, miRNAs 可以是未来治疗学或治疗学的目标。在这评论,我们检验通常观察是在 PCa 基因表示分析的 de-regulated 并且在 PCa 开始和前进考察这些 miRNAs 的潜在的贡献到重要小径的 miRNAs 大多数。 | Binod Kumar Shawn E Lupold | 2016 | Asian Journal of Andrology2016，18，4： | 6 |
| 2 | SARS-COV-2 infection(coronavirus disease 2019)for the gastrointestinal consultant显示文摘The current pandemic due to the severe acute respiratory syndrome coronavirus 2 has caused an extreme burden for health care systems globally,and the number of cases is expected to continue to increase,at least in the immediate future.The virus is estimated to have infected more than 1.5 million individuals.The available reports suggest that gastrointestinal(GI)involvement in coronavirus disease 2019(COVID-19)is common and in some cases the GI symptoms may precede the respiratory symptoms.In addition to direct effects of severe acute respiratory syndrome coronavirus 2,the infected patients remain at risk for the complications commonly managed by gastroenterology and hepatology consultants.The most commonly reported GI manifestation of COVID-19 is diarrhea,which is reported in a third to up to more than half of the patients.Mild to moderate elevation of the liver enzymes are also common,although no case of acute liver failure has been reported so far.Many of the medications used for treatment of COVID-19 can also be associated with GI symptoms or liver injury and can be included in the differential diagnosis in these patients.Although the diagnosis of the infection is currently based on RNA analysis in respiratory samples,the available literature on fecal shedding of this virus suggests that fecal RNA testing might prove to be a useful diagnostic test.It is reasonable to delay all non-urgent endoscopic procedures during the peak of the pandemic and use additional protective equipment such as N95 respirators during endoscopy while most patients can be considered high risk for having been exposed to the virus. | Kaveh Hajifathalian Srihari Mahadev Robert E Schwartz Shawn Shah Kartik Sampath Felice Schnoll-Sussman Robert S Brown Jr David Carr-Locke David E Cohen Reem Z Sharaiha | 2020 | World Journal of Gastroenterology2020，26，14： | 2 |
| 3 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 4 | Synthesis, characterization, and use of asymmetric pyrenyl - gemini suffactants as emissive components in DNA- lipoplex systems 显示文摘 | Chuanzhong Wang Shawn D Wettig Marianna Foldvari Ronald E VerraU | 2007 | Langmuir2007，23，： | 1 |
| 5 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 6 | Effects of atorvastatin on lipid metabolism in normolipidernic and hereditary, hyperdipidemie, non-laying hens显示文摘 | ROBERT G E ZHONG Y SHAWN S | 2006 | Biochemistry and Molecular Biology2006，143，3： | 1 |
| 7 | Complex distal humeral fractures: internal fixation with a principle-based parallel-plate technique显示文摘 | Joaquin SS Michael E Shawn W | 2008 | JBJS2008，90，： | 1 |
| 8 | Development of a general purpose thermal-hydraulic software and its application to fuel injection systems显示文摘 | Babajide Kolade Michael E Boghosian P S Reddy Shawn Gallagher | 2003 | SAE2003，，： | 1 |
| 9 | A conceptual framework for the study of human ecosystems in urban areas显示文摘 | Steward T A Pickett William R Burch Jr Shawn E Dalton | 1997 | Urban Ecosystems1997，1，4： | 1 |
| 10 | The scaling of a- coustic streaming for application in micro-fluidic de- vices显示文摘 | Kenneth D F Shawn E M Keith M | 2003 | Applied Acoustics2003，64，： | 1 |
| 11 | More data on Major depression as an antecedent risk factor for first onset of chronic,back pain显示文摘 | Currie E Shawn R Wang JL | 2005 | Psychological Medicine2005，35，9： | 1 |
| 12 | Aboriginal,Anglo and Immigrant Australian Students' Motivational Beliefs about Academic Success:Are There Cultural Differences显示文摘 | Dennis M M Hojn H Martin D and Shawn V E | 1998 | Journal of Educational Psychology1998，90，4： | 1 |
| 13 | Development of a rapid assimilable organic carbon method for water 显示文摘 | Lechevallier M W Shawn E Kaplan L A | 1993 | Appllied Environmental Microbiology1993，59，5： | 1 |
| 14 | Experimental demonstration of guiding and bending of electromagnetic waves in a photonic crystal 显示文摘 | Shawn Y L Chow E Hietala V | 1998 | Science1998，282，： | 1 |
| 15 | Design of optimal minimum phase FIR filters using discrete hilbert transforms 显示文摘 | Niranjan D V Brian L E Shawn R M | 2000 | IEEE Transactions on Signal Processing2000，48，5： | 1 |
| 16 | The Income Redistribution Effects of Texas State Lottery Games显示文摘 | PRICE DONALD E SHAWN NOVAK | 2000 | Public Finance Rev2000，28，1： | 1 |
| 17 | Electromagnetic signal modication in a localized high-speed plasma flow: simulations and experimental validation of a stationary plasma thruster显示文摘 | Shawn G O Brian E G Fergason S D | 2006 | Computer & Fluids2006，35，： | 1 |
| 18 | FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles显示文摘The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies.Over the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats.Yet,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging.In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels.Combining the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,respectively.This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental stud-ies.In order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences.On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2020 | Fungal Diversity2020，，6： | 1 |
| 19 | 显示文摘 | Hu Xiaodong Jenkins Shawn E Min Byung G | 2003 | Mac- romol Mater Eng2003，288，11： | 1 |
| 20 | Factors controlling the concentration of soluble phosphorus in the Mississippi Estuary显示文摘 | LEWIS E F SHAWN L | 1985 | Limno Oceangor1985，30，4： | 1 |
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