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| 1 | Surveillance of Hand,Foot,and Mouth Disease in China's Mainland (2008-2009)显示文摘Objective Since HFMD was designated as a class C communicable disease in May 2008,18 months surveillance data have been accumulated to December 2009.This article was to describe the distribution of HFMD for age,sex,area,and time between 2008 and 2009,to reveal the characteristics of the epidemic.Methods We analyzed weekly reported cases of HFMD from May 2008 to December 2009,and presented data on the distribution of age,sex,area and time.A discrete Poisson model was used to detect spatial-temporal clusters of HFMD.Results More than 1 065 000 cases of HFMD were reported in China's Mainland from May 2008 to December 2009 (total incidence:12.47 per 10 000).Male incidence was higher than female for all ages and 91.9% of patients were <5 years old.The incidence was highest in Beijing,Shanghai,Zhejiang and Hainan.The highest peak of HFMD cases was in April and the number of cases remained high from April to August.The spatial-temporal distribution detected four clusters.Conclusion Children <5 years old were susceptible to HFMD and we should be aware of their vulnerability.The incidence was higher in urban than rural areas,and an annual pandemic usually starts in April. | ZHU Qi HAO YuanTao MA JiaQi YU ShiCheng WANG Yu | 2011 | Biomedical and Environmental Sciences2011，24，4： | 73 |
| 2 | Comparisons of cropland area from multiple datasets over the past 300 years in the traditional cultivated region of China显示文摘陆地使用 / 盖住变化是在气候和生态的模拟的一个重要参数。尽管他们广泛地在社区,半自动地面防空系统数据集和 HYDE 数据集被使用了,二代表性的全球历史的陆地使用数据集,很少在地区性的规模关于他们的精确性被估计。这里,我们为中国(TCRC ) 的传统的栽培区域执行了一些评价在上持续 300 年,由把 SAGE2010 和 HYDE (v3.1 ) 与中国历史的农田数据集(CHCD ) 作比较。比较在三空间规模被执行:由 60 km 格子房间的全部学习区域,省的区域和 60 km。结果证明(1 ) 从 SAGE2010 的农田区域从 CHCD 是多于那的大部分;而且,以在 1950 以后的从 1700 ~ 1950 和 0.34% 的 0.51% 的率的生长从 CHCD 与那也不一致。(2 ) HYDE 数据集(v3.1 ) 在全部学习区域上比半自动地面防空系统数据集接近了 CHCD 数据集。然而,大偏爱能被 60 km 格子房间规模在省的规模和 60 km 检测。有比70%大的偏爱的格子房间的百分比(<-70%或>70%)并且90%(<-90%或>90%)当那些有的偏爱为仅仅5%6%从10%~10%并且从30%~30%报道 时,分别地说明了全部的格子房间的56%63%和40%45%并且17%全部的格子房间分别地。(3 ) 用本地历史的档案,有高精确性的历史的数据集将是改进气候和生态的模拟的精确性的一个珍贵方法重建。 | HE Fanneng LI Shicheng ZHANG Xuezhen GE Quansheng DAI Junhu | 2013 | Journal of Geographical Sciences2013，23，6： | 21 |
| 3 | A Road Extraction Method for Remote Sensing Image Based on Encoder-Decoder Network显示文摘According to the characteristics of the road features,an Encoder-Decoder deep semantic segmentation network is designed for the road extraction of remote sensing images.Firstly,as the features of the road target are rich in local details and simple in semantic features,an Encoder-Decoder network with shallow layers and high resolution is designed to improve the ability to represent detail information.Secondly,as the road area is a small proportion in remote sensing images,the cross-entropy loss function is improved,which solves the imbalance between positive and negative samples in the training process.Experiments on large road extraction datasets show that the proposed method gets the recall rate 83.9%,precision 82.5%and F1-score 82.9%,which can extract the road targets in remote sensing images completely and accurately.The Encoder-Decoder network designed in this paper performs well in the road extraction task and needs less artificial participation,so it has a good application prospect. | Hao HE Shuyang WANG Shicheng WANG Dongfang YANG Xing LIU | 2020 | Journal of Geodesy and Geoinformation Science2020，3，2： | 20 |
| 4 | Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer显示文摘渗入肿瘤的 Tregs 的起源,肿瘤免疫力的抑制的批评调停人,是不清楚的。这里,,我们证明在人的乳癌的渗入肿瘤的天真的 CD4 + T 房间和 Tregs 有重叠 TCR 全部剧目几乎别与传播 Tregs 重叠,建议 intratumoral Tregs 主要在 situ 而非从招募的 Tregs 从天真的 T 房间发展。而且,许多天真的 CD4 + T 房间和 Tregs 密切被相关,两个显示的穷人为乳癌病人的预后。天真的 CD4 + T 房间与许多生产 CCL18 巨噬细胞成比例遵守肿瘤片。而且,采纳地转移的人的天真的 CD4 + T 房间以一种 CCL18 依赖的方式渗入人的乳癌 orthotopic 异种皮移植。在在人性化的鼠标的人的乳癌异种皮移植,由将 PITPNM3 的表达式击倒堵住天真的 CD4 + T 房间的招募进肿瘤, CCL18 受体,显著地减少 intratumoral Tregs 并且禁止肿瘤前进。这些调查结果建议那个乳房渗入肿瘤的 Tregs 从在 situ 区分进 Tregs 的传播天真的 CD4 + T 房间的趋化性产生。由防碍 CCL18 的 PITPNM3 识别禁止天真的 CD4 + T 房间招募进肿瘤可以是为 anticancer 免疫疗法的吸引人的策略。 | Shicheng Su Jianyou Liao Jiang Liu Di Huang Chonghua He Fei Chen LinBing Yang Wei Wu Jianing Chen Ling Lin Yunjie Zeng Nengtai Ouyang Xiuying Cui Herui Yao Fengxi Su Jian-dong Huang Judy Lieberman Qiang Liu Erwei Song | 2017 | Cell Research2017，27，4： | 19 |
| 5 | Crop cover reconstruction and its effects on sediment retention in the Tibetan Plateau for 1900-2000显示文摘地理上明确的历史的陆地使用和陆地盖子数据集逐渐地在人的活动的气候、生态的效果的研究被要求。在这研究,把历史的人口数据用作一个代理, Qinghai 省的省的农田区域和西藏为 1900, 1930,和 1950 的自治区域(tar ) 被估计。为 1980 和 2000 的 Qinghai 和 TAR 的农田区域与修订从出版统计数据被获得。用为耕作模型的陆地适用性,为第 20 世纪的省的农田区域与 1 | LI Shicheng WANG Zhaofeng ZHANG Yili | 2017 | Journal of Geographical Sciences2017，27，7： | 16 |
| 6 | Apatite fission track dating evidence on the tectonization of Gangdese block, south Qinghai-Tibetan Plateau显示文摘This work makes the quantitative constrain on tectonizations of the Gangdese block, south Qinghai-Tibetan Plateau. Apatite fission track (AFT) dating analyses of 15 samples collected across the Gangdese block show that the Gangdese block went through two periods of tectonizations, during -37.2-18.5 Ma and 18.5 - 8.0 Ma in the south Gangdese block, and during -47.6-5.3 Ma and 5.3-0 Ma in the middle Gangdese block. Different upliftings did not take place in the first period and rapid uplifting occurred in the late period. Meantime, there are some differences be-tween the south and middle Gangdese block. Their uplifting rate is 180 m/Ma and 70 m/Ma respectively. The rapid up-lifting time in the middle Gangdese block lagged behind the time in the south Gangdese block. It is Chala-Jiacuo-Riduo fault zone that is similar to the Yarlung Zangbo fault zone in control of the tectonization. | YUAN Wanming WANG Shicheng LI Shengrong YANG Zhiqiang | 2002 | Chinese Science Bulletin2002，47，3： | 13 |
| 7 | Real-time fault detection method based on belief rule base for aircraft navigation system显示文摘Real-time and accurate fault detection is essential to enhance the aircraft navigation system's reliability and safety. The existent detection methods based on analytical model draws back at simultaneously detecting gradual and sudden faults. On account of this reason, we propose an online detection solution based on non-analytical model. In this article, the navigation system fault detection model is established based on belief rule base (BRB), where the system measuring residual and its changing rate are used as the inputs of BRB model and the fault detection function as the output. To overcome the drawbacks of current parameter optimization algorithms for BRB and achieve online update, a parameter recursive estimation algorithm is presented for online BRB detection model based on expectation maximization (EM) algorithm. Furthermore, the proposed method is verified by navigation experiment. Experimental results show that the proposed method is able to effectively realize online parameter evaluation in navigation system fault detection model. The output of the detection model can track the fault state very well, and the faults can be diagnosed in real time and accurately. In addition, the detection ability, especially in the probability of false detection, is superior to offline optimization method, and thus the system reliability has great improvement. | Zhao Xin Wang Shicheng Zhang Jinsheng Fan Zhiliang Min Haibo | 2013 | Chinese Journal of Aeronautics2013，26，3： | 13 |
| 8 | Design and demonstration of a next-generation air quality attainment assessment system for PM_(2.5)and O_3显示文摘Due to the increasingly stringent standards, it is important to assess whether the proposed emission reduction will result in ambient concentrations that meet the standards. The Software for Model Attainment Test—Community Edition(SMAT-CE) is developed for demonstrating attainment of air quality standards of O3 and PM2.5. SMAT-CE improves computational efficiency and provides a number of advanced visualization and analytical functionalities on an integrated GIS platform. SMAT-CE incorporates historical measurements of air quality parameters and simulated air pollutant concentrations under a number of emission inventory scenarios to project the level of compliance to air quality standards in a targeted future year. An application case study of the software based on the U.S. National Ambient Air Quality Standards(NAAQS) shows that SMAT-CE is capable of demonstrating the air quality attainment of annual PM2.5and 8-hour O3 for a proposed emission control policy. | Hua Wang Yun Zhu Carey Jang Che-Jen Lin Shuxiao Wang Joshua S.Fu Jian Gao Shuang Deng Junping Xie Dian Ding Xuezhen Qiu Shicheng Long | 2015 | Journal of Environmental Sciences2015，27，3： | 11 |
| 9 | Development and case study of a science-based software platform to support policy making on air quality显示文摘This article describes the development and implementations of a novel software platform that supports real-time, science-based policy making on air quality through a user-friendly interface. The software, RSM-VAT, uses a response surface modeling(RSM) methodology and serves as a visualization and analysis tool(VAT) for three-dimensional air quality data obtained by atmospheric models. The software features a number of powerful and intuitive data visualization functions for illustrating the complex nonlinear relationship between emission reductions and air quality benefits. The case study of contiguous U.S.demonstrates that the enhanced RSM-VAT is capable of reproducing the air quality model results with Normalized Mean Bias < 2% and assisting in air quality policy making in near real time. | Yun Zhu Yanwen Lao Carey Jang Chen-Jen Lin Jia Xing Shuxiao Wang Joshua S.Fu Shuang Deng Junping Xie Shicheng Long | 2015 | Journal of Environmental Sciences2015，27，1： | 10 |
| 10 | A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts显示文摘Terminally differentiated cells can be generated by lineage reprogramming,which is,however,hindered by incomplete conversion with residual initial cell identity and partial functionality. Here, we demonstrate a new reprogramming strategy by mimicking the natural regeneration route, which permits generating expandable hepatic progenitor cells and functionally competent human hepatocytes. Fibroblasts were first induced into human hepatic progenitor-like cells (hHPLCs), which could robustly expand in vitro and efficiently engraft in vivo. Moreover, hHPLCs could be efficiently induced into mature human hepatocytes (hiHeps) in vitro, whose molecular identity highly resembles primary human hepatocytes (PHHs). Most importantly, hiHeps could be generated in large quantity and were functionally competent to replace PHHs for drug-metabolism estimation, toxicity prediction and hepatitis B virus infection modeling. Our results highlight the advantages of the progenitor stage for successful lineage reprogramming. This strategy is promising for generating other mature human cell types by lineage reprogramming. | Bingqing Xie Da Sun Yuanyuan Du Jun Jia Shicheng Sun Jun Xu Yifang Liu Chengang Xiang Sitong Chen Huangfan Xie Qiming Wang Guangya Li Xuehui LYU Hui Shen Shiyu Li Min Wu Xiaonan Zhang Yue Pu Kuanhui Xiang Weifeng Lai Peng Du Zhenghong Yuan Cheng Li Yan Shi Shichun Lu Hongkui Deng | 2019 | Cell Research2019，29，9： | 9 |
| 11 | A case study of development and application of a streamlined control and response modeling system for PM_(2.5)attainment assessment in China显示文摘This article describes the development and application of a streamlined air control and response modeling system with a novel response surface modeling-linear coupled fitting method and a new module to provide streamlined model data for PM_(2.5) attainment assessment in China.This method is capable of significantly reducing the dimensions required to establish a response surface model,as well as capturing more realistic response of PM_(2.5) to emission changes with a limited number of model simulations.The newly developed module establishes a data link between the system and the Software for Model Attainment Test—Community Edition(SMAT-CE),and has the ability to rapidly provide model responses to emission control scenarios for SMAT-CE using a simple interface.The performance of this streamlined system is demonstrated through a case study of the Yangtze River Delta(YRD) in China.Our results show that this system is capable of reproducing the Community Multi-Scale Air Quality(CMAQ) model simulation results with maximum mean normalized error < 3.5%.It is also demonstrated that primary emissions make a major contribution to ambient levels of PM_(2.5) in January and August(e.g.,more than50%contributed by primary emissions in Shanghai),and Shanghai needs to have regional emission control both locally and in its neighboring provinces to meet China's annual PM_(2.5)National Ambient Air Quality Standard.The streamlined system provides a real-time control/response assessment to identify the contributions of major emission sources to ambient PM_(2.5)(and potentially O_3 as well) and streamline air quality data for SMAT-CE to perform attainment assessments. | Shicheng Long Yun Zhu Carey Jang Che-Jen Lin Shuxiao Wang Bin Zhao Jian Gao Shuang Deng Junping Xie Xuezhen Qiu | 2016 | Journal of Environmental Sciences2016，28，3： | 9 |
| 12 | Application of GIS in Mineral Resource Prediction of Synthetic Information显示文摘This paper introduces the formation mechanism and synthetic information prediction of large and superlarge deposits in Shandong Province by analyzing and studying on the GIS platform. The authors established a prospecting model of synthetic information from large and superlarge gold deposit concentration region, and the multi-source spatial database from concentration region of deposits and anomalies. On the basis of the spatial database, a target map layer, a model map layer and a predictive map layer were set up. Based on these map layers, geological variables of the model unit and predictive unit were extracted, then launched location and quantitative prediction of the gold deposit concentration region. The achievement of predicting large and superlarge deposits by the GIS platform has enabled the authors to design automation (or semi-automatic) interpretation subsystems, namely geophysics, geochemistry, geologic prospecting and comprehensive prognosis, and a set of the applicable GIS software for mineral resources prognosis of synthetic information. | Ye Shuisheng Wang Shicheng Li Deqiong Mineral Resources Institute of Comprehensive Information Prediction, Jilin University, Changchun 130026 | 2003 | Journal of China University of Geosciences2003，14，3： | 7 |
| 13 | Evaluating the accuracy of Chinese pasture data in global historical land use datasets显示文摘Global historical land use datasets are widely used in global environmental change studies; however, uncertainties in the included pasture data have not been evaluated. In this study, using trend, relative difference ratio(RDR), and spatial comparisons, we evaluated the accuracy of China pasture data in the HYDE(versions 3.1 and 3.2), SAGE, and PJ datasets using historical document-based reconstructions, including the land use datasets for China covering 1935–1997(hereafter Ge-dataset)and Northeast China covering the 1700 s–2000(hereafter Ye-dataset), and the satellite-based China's Land-Use/cover Datasets(CLUDs) for 1980–2015. Four important results were obtained.(1) China pasture area in the HYDE, SAGE, and PJ datasets and grassland area in the Ge-dataset, Ye-dataset, and CLUDs show both disparate trends and large differences in absolute values.(2)Spatially, 50.9%, 52.8%, and 63.0% pasture/grassland grids in 2000 had RDRs greater than 60% between HYDE3.1, HYDE3.2,and SAGE datasets, and CLUDs, respectively. The percentage of grids with RDRs less than 20% were 24.9%, 26.7%, and 16.0%,respectively.(3) Based on HYDE3.2, the spatial distribution of pasture in Northeast China over the last 300 year has expanded,which is in contrast to the results from the Ye-dataset, which shows the spatial distribution of grassland shrinking because of human reclamation activities.(4) The large contrasts between the global datasets and Chinese native datasets are due to differences in pasture/grassland definitions, land use practices, and spatial reconstruction methods. | Fanneng HE Shicheng LI Fan YANG Meijiao LI | 2018 | Science China Earth Sciences2018，61，11： | 7 |
| 14 | Reconstruction of cropland area and spatial distribution in the mid-Northern Song Dynasty (AD1004-1085)显示文摘为了理解历史的导致人的土地,盖住变化和它的气候的效果,与明确的空间信息创造历史的陆地使用数据集是必要的。用税农田区域和从历史的文件编的家庭的数字,我们在每陆(在北歌王朝的一个省级的政治区域) 以内估计了真实农田区域和人口在中间 -- 北歌王朝(AD1004-1085 ) 。评价通过分析税,人口和农业开发的当代的政策被完成。然后,我们把政治基于区域的农田区域变换成地理上明确的格子在由 60 km 的 60 km 的房间尺寸的基于房间的部分农田。变换作为独立变量用地志的斜坡,高度和人口密度基于每个格子房间的精明的耕作适用性。作为结果,在在 1070 年代的北歌领土以内的农田的全部的区域被估计是大约 7.2 亿亩(中国区域单位, 1 亩 = 666.7 m2 ) ,哪个 40.1% 和 59.9% 分别地发生在北方和南方。人口被估计是大约 8720 万,哪个 38.7% 和 61.3% 分别地在北方和南方,并且人均的农田区域是大约 8.2 亩。国家吝啬的开垦比率(即到全部的土地的农田区域的比率区域;RRA 此后为短) 是一回 16.6% 。平凡区域例如诺思中国平原,中间和长江的更低的活动范围, Guanzhong 平原,包围东廷·莱克和波伊昂·莱克和四川盆的平原,有更高的 RRA,主要是超过 40% ;当时多山、多山的区域例如 Nanling 山的南方,西南区域(排除 Chengdu 平原) ,黄土高原和东南沿海的区域,有更低的 RRA,是不到 20% 。而且, RRA 与地志的斜坡和高度变化了。在低高度(250 m ) 的区域,中间的高度(250100 m ) 和高高度(10003500 m ) ,有 4.43 亿, 2.15 亿并且 6400 万亩农田分别地并且他们的地区性的吝啬的 RRA 分别地是 27.5% , 12.6% 和 7.2% 。在扁平的斜坡,轻轻的斜坡,中等斜坡和陡峭的斜坡的区域,有 1.16 亿, 4.56 亿, 1.44 亿并且 200 万亩农田分别地并且他们的地区性的吝啬的 RRA 分别地是 34.6% , 20.7% , 8.5% 和 2.3% 。 | HE Fanneng LI Shicheng ZHANG Xuezhen | 2012 | Journal of Geographical Sciences2012，22，2： | 7 |
| 15 | Mulching mode and planting density affect canopy interception loss of rainfall and water use efficiency of dryland maize on the Loess Plateau of China显示文摘High and efficient use of limited rainwater resources is of crucial importance for the crop production in arid and semi-arid areas. To investigate the effects of different soil and crop management practices(i.e., mulching mode treatments: flat cultivation with non-mulching, flat cultivation with straw mulching, plastic-covered ridge with bare furrow and plastic-covered ridge with straw-covered furrow; and planting density treatments: low planting density of 45,000 plants/hm^2, medium planting density of 67,500 plants/hm^2 and high planting density of 90,000 plants/hm^2) on rainfall partitioning by dryland maize canopy, especially the resulted net rainfall input beneath the maize canopy, we measured the gross rainfall, throughfall and stemflow at different growth stages of dryland maize in 2015 and 2016 on the Loess Plateau of China. The canopy interception loss was estimated by the water balance method. Soil water storage, leaf area index, grain yield(as well as it components) and water use efficiency of dryland maize were measured or calculated. Results showed that the cumulative throughfall, cumulative stemflow and cumulative canopy interception loss during the whole growing season accounted for 42.3%–77.5%, 15.1%–36.3% and 7.4%–21.4% of the total gross rainfall under different treatments, respectively. Soil mulching could promote the growth and development of dryland maize and enhance the capability of stemflow production and canopy interception loss, thereby increasing the relative stemflow and relative canopy interception loss and reducing the relative throughfall. The relative stemflow and relative canopy interception loss generally increased with increasing planting density, while the relative throughfall decreased with increasing planting density. During the two experimental years, mulching mode had no significant influence on net rainfall due to the compensation between throughfall and stemflow, whereas planting density significantly affected net rainfall. The highest grain yield and water use efficiency of dryland maize were obtained under the combination of medium planting density of 67,500 plants/hm^2 and mulching mode of plastic-covered ridge with straw-covered furrow. Soil mulching can reduce soil evaporation and retain more soil water for dryland maize without reducing the net rainfall input beneath the maize canopy, which may alleviate the contradiction between high soil water consumption and insufficient rainfall input of the soil. In conclusion, the application of medium planting density(67,500 plants/hm^2) under plastic-covered ridge with bare furrow is recommended for increasing dryland maize production on the Loess Plateau of China. | ZHENG Jing FAN Junliang ZHANG Fucang YAN Shicheng GUO Jinjin CHEN Dongfeng LI Zhijun | 2018 | Journal of Arid Land2018，10，5： | 6 |
| 16 | Development of an integrated policy making tool for assessing air quality and human health benefits of air pollution control显示文摘有效空气质量管理是批评的保护公共健康免受空气污染的不利影响的伤害。为了评估空气污染的有效性,控制策略, US 环境保护机构(美国 EPA )开发了软件让模型成就测试社区编辑( SMAT-CE )估计排放减小的空气质量成就,并且印射的环境好处和编辑( BenMAP-CE )分别地空气质量改进有益于评估健康和经济的分析节目社区。后来科学的决策要求及时、协调的信息,开发在 SMAT-CE 之间的连接,进一个综合评价平台的 BenMAP-CE 是合乎需要的。探讨这需要,连接 SMAT-CE 到 BenMAP-CE 的一个新模块被开发了并且测试。新模块优化对优秀、人的健康为建议空气污染控制策略有益于的空气的评价。它也实现没有损害精确性,显著地提高计算效率的一个优化数据 gridding 算法。综合软件包裹的性能通过案例研究被表明评估质量和联系经济下午 2.5 的公民级的控制策略有益于的空气。案例研究的结果证明建议排放减小基于 US 国家周围的空气质量标准从 379 ~ 25 减少 nonattainment 地点的数字,从改进公共健康每年多于经济好处的 3340 亿美元导致。在这研究的基于科学的软件工具的集成提高为政策制造者开发有效、优化的排放控制策略的效率。 | Xuezhen QIU Yun ZHU Carey JANG Che-Jen LIN Shuxiao WANG Joshua FU Junping XIE Jiandong WANG Dian DING Shicheng LONG | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 6 |
| 17 | Numerical and experimental investigation into hypersonic boundary layer transition induced by roughness elements显示文摘In this work, the Direct Numerical Simulation(DNS) and Oil-Film Interferometry(OFI)technique are used to investigate the hypersonic boundary layer transition induced by single and double roughness elements at Mach number 5. For single roughness, the DNS results showed that both horseshoe vortices and hairpin vortices caused by shear layer instability can affect the boundary layer instability. The generation of the near-wall unstable structure is the key point of boundary layer transition behind the roughness element. At the downstream of the roughness element, the interaction between horseshoe vortices and hairpin vortices will spread in the spanwise direction.For double roughness elements, the effect of the spacing between roughness elements on the transition is studied. It is found that the case of higher spacing between roughness elements is more effective for inducing transition than the lower one. The interaction between two adjacent roughness elements can suppress the evolution of horseshoe vortices in the downstream and trigger the instability of shear layer. Thus, the transition will be suppressed accordingly. | Hao DONG Shicheng LIU Xi GENG Song LIU Liming YANG Keming CHENG | 2019 | Chinese Journal of Aeronautics2019，32，3： | 6 |
| 18 | High-throughput droplet microfluidic synthesis of hierarchical metal-organic framework nanosheet microcapsules显示文摘Using two-dimensional(2D)metal-organic framework(MOF)nanosheets as new building blocks to create more complex architectures at the mesoscopic/macroscopic scale has attracted extensive interest in recent years.Nevertheless,it remains a great challenge to assemble MOF nanosheets into hierarchical hollow structures so far.In this paper,we describe a successful example of hierarchical MOF nanosheet microcapsules,with precisely controlled sizes,produced on large scale within minutes with a continuous droplet microfluidic strategy.Following a reaction/diffusion growth mechanism,the microcapsule shells feature a continuous smooth inner layer and a porous outer layer.Such hierarchical structure enables the encapsulation of magnetite nanoparticles inside and loading of dense gold nanoparticles outside the microcapsules,which exhibit highly efficient heterogeneous catalytic activity and easy recyclability.The present microfluidic assembly method offers a new pathway for preparing hierarchical MOF nanosheet structures,with the potential for extension to the formation of other 2D nanosheets in general. | Songting Wu Zhong Xin Shicheng Zhao Shengtong Sun | 2019 | Nano Research2019，12，11： | 6 |
| 19 | Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a global pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2).SARS-Co V-2 infection was first detected in Wuhan,China in late December 2019.The virus was spreading rapidly to other cities of China and accumulating cases had been reported(Li et al.2020). | Xiaoping Chen Qunqun Jiang Zhiyong Ma Jiaxin Ling Wenjia Hu Qian Cao Pingzheng Mo Lei Yao Rongrong Yang Shicheng Gao Xien Gui Wei Hou Yong Xiong Jinlin Li Yongxi Zhang | 2020 | Virologica Sinica2020，35，6： | 6 |
| 20 | A new method to optimize the fracture geometry of a frac-packed well in unconsolidated sandstone heavy oil reservoirs显示文摘The worldwide proven recoverable reserves of conventional oil are less than the amount of the heavy oil.Owing to weakly consolidated formation,sand production is an important problem encountered during oil production in heavy oil reservoirs,for which frac-pack technique is one of the most common treatments.Hence,how to obtain the optimal fracture geometry is the key to increasing well production and preventing sand.Due to the faultiness that current optimization of the fracture geometry only depends on well productivity,fracture-flow fraction was used to describe the contribution of the fracture collecting and conducting fluids from the reservoir.The higher the fracture-flow fraction,the more likely bilinear flow pattern occurs,thus leading to smaller flow resistance and better results in oil productivity and sand prevention.A reservoir numerical simulation model was established to simulate the long-term production dynamic of a fractured well in rectangular drainage areas.In order to reach the aim of increasing productivity meanwhile preventing sand,a new method based on Unified Fracture Design was developed to optimize the fracture geometry.For a specific reservoir and a certain amount of proppant injected to the target layer,there exits an optimal dimensionless fracture conductivity which corresponds to the maximum fracture-flow fraction,accordingly we can get the optimal fracture geometry.The formulas of the optimal fracture geometry were presented on square drainage area conditions,which are very convenient to apply.Equivalent Proppant Number was used to eliminate the impact of aspect ratios of rectangular drainage area,then,the same method to optimize the fracture geometry as mentioned for square drainage areas could be adopted too. | BIAN XiaoBing ZHANG ShiCheng ZHANG JingChen WANG Fei | 2012 | Science China(Technological Sciences)2012，55，6： | 5 |
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