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| 1 | Ultrafast optical spectroscopy evidence of pseudogap and electronphonon coupling in an iron-based superconductor KCa_(2)Fe_(4)As_(4)F_(2)显示文摘We use ultrafast optical spectroscopy to study the nonequilibrium quasiparticle relaxation dynamics of the iron-based superconductor KCa_(2)Fe_(4)A_(s4)F_(2)with T_(c)= 33.5 K. Our results reveal a possible pseudogap(△_(PG)=(2.4 ± 0.1) me V) below T*≈ 50 K but prior to the opening of a superconducting gap(△SC(0) ≈(4.3 ± 0.1) me V). Measurements under high pump fluence reveal two distinct, coherent phonon oscillations with 1.95 and 5.51 THz frequencies, respectively. The high-frequency A1 g(2) mode corresponds to the c-axis polarized vibrations of Fe As planes with a nominal electron-phonon coupling constant λA1 g(2)= 0.194 ± 0.02.Our findings suggest that the pseudogap is likely a precursor of superconductivity, and the electron-phonon coupling may play an essential role in the superconducting pairing in KCa_(2)Fe_(4)A_(s4)F_(2). | Chen Zhang Qi-Yi Wu Wen-Shan Hong Hao Liu Shuang-Xing Zhu Jiao-Jiao Song Yin-Zou Zhao Fan-Ying Wu Zi-Teng Liu Shu-Yu Liu Ya-Hua Yuan Han Huang Jun He Shiliang Li Hai-Yun Liu Yu-Xia Duan Hui-Qian Luo Jian-Qiao Meng | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，3： | 7 |
| 2 | Fluid-structure interaction simulation of three-dimensional flexible hydrofoil in water tunnel显示文摘The closely coupled approach combined with the finite volume method(FVM) solver and the finite element method(FEM) solver is used to investigate the fluid-structure interaction(FSI) of a three-dimensional cantilevered hydrofoil in the water tunnel. The FVM solver and the coupled approach are verified and validated by comparing the numerical predictions with the experimental measurements, and good agreement is obtained concerning both the lift on the foil and the tip displacement. In the noncavitating flow, the result indicates that the growth of the initial incidence angle and the Reynolds number improves the deformation of the foil, and the lift on the foil is increased by the twist deformation. The normalized twist angle and displacement along the span of the hydrofoil for different incidence angles and Reynolds numbers are almost uniform. For the cavitation flow, it is shown that the small amplitude vibration of the foil has limited influence on the developing process of the partial cavity, and the quasi two-dimensional cavity shedding does not change the deformation mode of the hydrofoil. However, the frequency spectrum of the lift on the foil contains the frequency which is associated with the first bend frequency of the hydrofoil. | Shiliang HU Chuanjing LU Yousheng HE | 2016 | Applied Mathematics and Mechanics(English Edition)2016，37，1： | 5 |
| 3 | Overexpression of amplified in breast cancer 1 (AIB1) gene promotes lung adenocarcinoma aggressiveness in vitro and in vivo by upregulating C-X-C motif chemokine receptor 4显示文摘Background:We previously found that overexpression of the gene known as amplified in breast cancer 1(AIB1)was associated with lymph node metastasis and poor prognosis in patients with lung adenocarcinoma.However,the role of AIB1 in that malignancy remains unknown.The present study aimed to investigate the function of AIB1 in the process of lung adenocarcinoma cell metastasis.Methods:A series of in vivo and in vitro assays were performed to elucidate the function of AIB1,while real-time PCR and Western blotting were utilized to identify the potential downstream targets of AIB1 in the process of lung adenocarcinoma metastasis.Rescue experiments and in vitro assays were performed to investigate whether the invasive-ness of AIB1-induced lung adenocarcinoma was mediated by C-X-C motif chemokine receptor 4(CXCR4).Results:The ectopic overexpression of AIB1 in lung adenocarcinoma cells substantially enhanced cell migration and invasive abilities in vitro and tumor metastasis in vivo,whereas the depletion of AIB1 expression substantially inhibited lung adenocarcinoma cell migration and invasion.CXCR4 was identified as a potential downstream target of AIB1 in lung adenocarcinoma.The knockdown of AIB1 greatly reduced CXCR4 gene expression at both the transcription and protein levels,whereas the knockdown of CXCR4 in cells with AIB1 ectopic overexpression diminished AIB1-induced migration and invasion in vitro and tumor metastasis in vivo.Furthermore,we found a significant positive association between the expression of AIB1 and CXCR4 in lung adenocarcinoma patients(183 cases),and the co-overexpression of AIB1 and CXCR4 predicted the poorest prognosis.Conclusions:These findings suggest that AIB1 promotes the aggressiveness of lung adenocarcinoma in vitro and in vivo by upregulating CXCR4 and that it might be usable as a novel prognostic marker and/or therapeutic target for this disease. | Liru He Haixia Deng Shiliang Liu Jiewei Chen Binkui Li Chenyuan Wang Xin Wang Yiguo Jiang Ningfang Ma Mengzhong Liu Dan Xie | 2018 | Cancer Communications2018，38，1： | 2 |
| 4 | Synthesis of single-crystalline tungsten nanowires by nickel-catalyzed vapor- phase method at 850C 显示文摘 | Wang Shiliang He Yuehui Zou Jin et at | 2007 | J Cryst Growth2007，306，： | 1 |
| 5 | Inhibition of calcium carbonate precipitation in NaCl brines from 25 to 90℃显示文摘 | Shiliang He A T Kan M B Tomson | 1999 | Applied Geochemistry1999，14，1： | 1 |
| 6 | Structure and field-emission properties of sub-micrometer-sized tungsten-whisker arrays fabricated by vapor deposition显示文摘 | Wang Shiliang He Yuehui Fang Xiaosheng | 2009 | Adv Mater2009，21，： | 1 |
| 7 | Inhibition of calcium carbonate precipitation in NaCl brines from 25 to 90 C 显示文摘 | He Shiliang | 1999 | Applied Geochemistry1999，14，1： | 1 |
| 8 | Mathematical in-hibitor model for barium sulfate scale control显示文摘 | Shiliang He Amy T Kan Mason B T | | 0，，07： | 1 |
| 9 | The nucleation kinetics of strontium sulfate in NaCl solution up to 6 m and 90℃ with or without inhibitors显示文摘 | He Shiliang Oddo J E Tomson M B | 1995 | Journal of Colloid and Interface Science1995，174，2： | 1 |
| 10 | Inhibition of calcium carbonate precipitation in NaCl brines from 25 to 90℃显示文摘 | Kan A T Tomson M B | 1999 | Applied Geochemistry1999，14，1： | 1 |
| 11 | Growth of singlecrystalline tungsten nanowires by an alloy-catalyzed method at 850℃显示文摘 | Shiliang Wang Yuehui He Jian Xu | 2008 | Journal of Materials Research2008，23，： | 1 |
| 12 | Design and Synthesis of a Series of Novel Macrocycle Janus Kinase 2 Inhibitors显示文摘Summary of main observation and conclusion Macrocycle has attracted the attention of many researchers in the field of medicinal chemistry due to its unique advantages and good prospects,but the difficulties in drug design and synthesis of macrocycle limit its applications.In this study,a series of macrocyclic derivatives designed from anaplastic lymphoma kinase(ALK)inhibitor lorlatinib were synthesized as Janus kinase 2(JAK2)selective inhibitors.Among them,17f had the best inhibitory activity(IC50=0.177μmol·L^-1)and selectivity for JAK2 over JAK1 and JAK3,which indicated that design of the macrocyclic derivatives might be a feasible strategy for the discovery of novel selective JAK2 inhihitors. | Yanling Wang Huan Ge Disha Wang Huan He Lu Li Yanyan Diao Zihao Shen Lili Zhu Shiliang Li Zhenjiang Zhao Honglin Li | 2019 | Chinese Journal of Chemistry2019，37，12： | 1 |
| 13 | Structure and field-emission properties of sub-micrometer-sized tungsten- whisker arrays fabricated by vapor deposition 显示文摘 | Wang Shiliang He Yuehui Fang Xiaosheng | 2009 | Advanced Materials2009，21，： | 1 |
| 14 | Synthesis of single-crystalline tungsten nanowires by nickel-catalyzed vapor-phase method at 850 ℃显示文摘 | Wang Shiliang He Yuehui | 2007 | Journal of Crystal Growth2007，306，2： | 1 |
| 15 | Synthesis of tungsten oxide tapered needles with nanotips 显示文摘 | Wang Shiliang He Yuehui Zou Jin | 2007 | Journal of Crystal Growth2007，303，2： | 1 |
| 16 | Growth of singlecrystalline tungsten nanowires by an alloy-catalyzed method at 850 degrees 显示文摘 | Wang Shiliang He Yuehui Xu jian | 2008 | Journal of Materials Research2008，23，1： | 1 |
| 17 | Novel tungsten oxide mieroneedles with nanosized tips 显示文摘 | He Yuehui Wang Shiliang Huang Baiyun | 2006 | Applied Physics Letters2006，88，22： | 1 |
| 18 | Synthesis of single- crystallline tungsten nanowires by nickel-catalyzed vapor-phase method at 850℃显示文摘 | Wang Shiliang He Yuehui Zou Jin | 2007 | Journal of Crystal Growth2007，306，2： | 1 |
| 19 | The nucleation kinetics of barium sulfate in NaCl solutions up to 6m and 90℃显示文摘 | Shiliang He Oddo J E Tomon M B | 1995 | Colloid and Interface Science1995，174，： | 1 |
| 20 | Formation and growth mechanism of tungsten oxide microtubules 显示文摘 | Wang Shiliang He Yuehui Huang Baiyun | 2006 | Chemical Physics Letters2006，427，46： | 1 |
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