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| 1 | 2D Materials Based Optoelectronic Memory: Convergence of Electronic Memory and Optical Sensor显示文摘Te continuous development of electron devices towards the trend of“More than Moore”requires functional diversifcation that can collect data(sensors)and store(memories)and process(computing units)information.Considering the large occupation proportion of image data in both data center and edge devices,a device integration with optical sensing and data storage and processing is highly demanded for future energy-efcient and miniaturized electronic system.Two-dimensional(2D)materials and their heterostructures have exhibited broadband photoresponse and high photoresponsivity in the confguration of optical sensors and showed fast switching speed,multi-bit data storage,and large ON/OFF ratio in memory devices.In addition,its ultrathin body thickness and transfer process at low temperature allow 2D materials to be heterogeneously integrated with other existing materials system.In this paper,we overview the state-of-the-art optoelectronic random-access memories(ORAMs)based on 2D materials,as well as ORAM synaptic devices and their applications in neural network and image processing.Te ORAM devices potentially enable direct storage/processing of sensory data from external environment.We also provide perspectives on possible directions of other neuromorphic sensor design(e.g.,auditory and olfactory)based on 2D materials towards the future smart electronic systems for artifcial intelligence. | Feichi Zhou Jiewei Chen Xiaoming Tao Xinran Wang Yang Chai | 2019 | Research2019，，1： | 6 |
| 2 | Diketopyrrolopyrrole-Au(I) as singlet oxygen generator for enhanced tumor photodynamic and photothermal therapy显示文摘Diketopyrrolopyrrole(DPP)derivatived photosensitizers(PSs)with near infrared(NIR)absorption and good photophysical properties have drawn tremendous attention in cancer phototherapy.However,current DPP derivatives present unsatisfactory quantum yield of singlet oxygen(1O2)due to the large energy gap between the excited singlet and triplet states.To tackle this challenge,herein the DPP core is functionalized with triphenylphosphine-Au(I)group(Th DPP-Au),leading to a high1O2 quantum yield of 0.65.Theoretical calculation attributes the enhancement to spin-orbit coupling and population of the triplet excition upon photoexcitation.The hydrophilic Th DPP-Au nanoparticals(NPs)are prepared via nano-reprecipitation,which displays homogeneous size and excellent light absorption ability(ε=4.382×104 M-1cm-1).And the Th DPP-Au NPs exhibit low dark toxicity and high phototoxicity,which can effectively kill tumor cells via 1O2 induced mitochondrial apoptotic pathway upon irradiation.Furthermore,in vivo experiments demonstrate that Th DPP-Au NPs can selective accumulation in tumor and present excellent synergistic photodynamic/photothermal therapy guided by fluorescence and photothermal dual imaging. | Xiaoyu Huang Rui Gu Jiewei Li Nan Yang Zijin Chen Weili Si Peng Chen Wei Huang Xiaochen Dong | 2020 | Science China Chemistry2020，63，1： | 3 |
| 3 | Dual confinement of polysulfides in boron-doped porous carbon sphere/graphene hybrid for advanced Li-S batteries显示文摘由做硼的多孔的碳范围和 graphene (BPCS-G ) 组成的混合结构被设计了并且向解决 polysulfide 梭问题综合了,它是当前的 Li-S 电池的最关键的问题。显示出高表面区域的建议混合结构(870 m 2??????????????? ? €畧湡湩?? 挠瑹獯湩 ?????? ㄠ‰ ????????????? 吠 ?? €?‰ ??????? ‰ ?????????????????????????? ￡桴?? | Wei Ai Jiewei Li Zhuzhu Du Chenji Zou Hongfang Du Xin Xu Yu Chen Hongbo Zhang Jianfeng Zhao Changming Li Wei Huang Ting Yu | 2018 | Nano Research2018，11，9： | 2 |
| 4 | Overexpression of amplified in breast cancer 1 (AIB1) gene promotes lung adenocarcinoma aggressiveness in vitro and in vivo by upregulating C-X-C motif chemokine receptor 4显示文摘Background:We previously found that overexpression of the gene known as amplified in breast cancer 1(AIB1)was associated with lymph node metastasis and poor prognosis in patients with lung adenocarcinoma.However,the role of AIB1 in that malignancy remains unknown.The present study aimed to investigate the function of AIB1 in the process of lung adenocarcinoma cell metastasis.Methods:A series of in vivo and in vitro assays were performed to elucidate the function of AIB1,while real-time PCR and Western blotting were utilized to identify the potential downstream targets of AIB1 in the process of lung adenocarcinoma metastasis.Rescue experiments and in vitro assays were performed to investigate whether the invasive-ness of AIB1-induced lung adenocarcinoma was mediated by C-X-C motif chemokine receptor 4(CXCR4).Results:The ectopic overexpression of AIB1 in lung adenocarcinoma cells substantially enhanced cell migration and invasive abilities in vitro and tumor metastasis in vivo,whereas the depletion of AIB1 expression substantially inhibited lung adenocarcinoma cell migration and invasion.CXCR4 was identified as a potential downstream target of AIB1 in lung adenocarcinoma.The knockdown of AIB1 greatly reduced CXCR4 gene expression at both the transcription and protein levels,whereas the knockdown of CXCR4 in cells with AIB1 ectopic overexpression diminished AIB1-induced migration and invasion in vitro and tumor metastasis in vivo.Furthermore,we found a significant positive association between the expression of AIB1 and CXCR4 in lung adenocarcinoma patients(183 cases),and the co-overexpression of AIB1 and CXCR4 predicted the poorest prognosis.Conclusions:These findings suggest that AIB1 promotes the aggressiveness of lung adenocarcinoma in vitro and in vivo by upregulating CXCR4 and that it might be usable as a novel prognostic marker and/or therapeutic target for this disease. | Liru He Haixia Deng Shiliang Liu Jiewei Chen Binkui Li Chenyuan Wang Xin Wang Yiguo Jiang Ningfang Ma Mengzhong Liu Dan Xie | 2018 | Cancer Communications2018，38，1： | 2 |
| 5 | Interstitial copper-doped edge contact for n-type carrier transport in black phosphorus显示文摘Black phosphorus(BP)has been shown as a promising two-dimensional(2D)material for electronic devices owing to its high carrier mobility.To realize complementary electronic circuits with 2D materials,it is important to fabricate both n-type and p-type transistors with the same channel material.By engineering the contact region with copper(Cu)-doped BP,here we demonstrate an n-type carrier transport in BP field-effect transistors(FETs),which usually exhibit strongly p-type characteristics.Cu metal atoms are found to severely penetrate into the BP flakes,which forms interstitial Cu(Cuint)-doped edge contact and facilitates the electron transport in BP.Our BP FETs in backgated configuration exhibit n-type dominant characteristics with a high electron mobility of^138 cm^2 V^−1 s^−1 at room temperature.The Schottky barrier height for electrons is relatively low because of the edge contact between Cuint-doped BP and pristine BP channel.The contact doping of BP by highly mobile Cu atoms gives rise to n-type transport property of BP FETs.Furthermore,we demonstrate a p-n junction on the same BP flake with asymmetric contact.This strategy on contact engineering can be further extended to other 2D materials. | Ziyuan Lin Jingli Wang Xuyun Guo Jiewei Chen Chao Xu Mingqiang Liu Bilu Liu Ye Zhu Yang Chai | 2019 | InfoMat2019，1，2： | 2 |
| 6 | Performance of LED with mixed wavelengths or two-phase culture on the growth and lipid accumulation of Chlorella pyrenoidosa显示文摘Chlorella pyrenoidosa,a type of lipid-rich green algae,features broad prospects for application in such fields as healthy foods,biodiesel and so on.The light-utilizing efficiency of the cells is a critical factor that influences the biomass and lipid contents of photoautotrophic microalgae.Inconsistent illumination wavelengths hinder microalgal growth.The patterns about the impacts of mixed light emitting diode(LED)wavelengths or two-phase culture over the growth and lipid accumulation of Chlorella pyrenoidosa were reported.Among the different LED wavelengths(white,purple,blue,green,yellow and red)at the light intensity of 200μmol/m2·s tested,red and green gave maximum biomass and lipid contents,respectively.Based on the discovery,two-phase(red was illuminated for 12 d in the first phase,and then shifted to green light for 8 d in the second phase,R→G)or mixed LED(R:G=3:7 or R:G=7:3)culture protocol was adopted for the high lipid-accumulation of Chlorella pyrenoidosa.The results indicated that the lipid contents of Chlorella pyrenoidosa treated with two-phase(R→G)or mixed LED culture was significantly higher than that of white light with the same intensity(p<0.05),and the highest lipid-accumulation rate was 26.37 mg/L·d in the two-phase culture.Fatty acid(FA)analysis showed that 13 types FAs were detected and unsaturated FAs were over 50%(w/w).26.8%-27.7%(w/w)palmitic acid(C16:0)was the major saturated FA,while the largest proportions of monounsaturated FA and polyunsaturated FA were oleic acid(C18:1)and linoleic acid(C18:2),respectively.Additionally,although no difference in the FA composition of Chlorella pyrenoidosa treated with different protocols was found,the absolute content did differ significantly,coinciding with that of the total lipids.Furthermore,the ratio of unsaturated FAs in Chlorella pyrenoidosa was significantly increased under the mixed LED(R:G=7:3)(p<0.05). | Bingquan Chu Jiewei Zhao Huimin Zheng Jinyan Gong Kai Chen Suwan Zhang Gongnian Xiao Yong He | 2021 | International Journal of Agricultural and Biological Engineering2021，14，1： | 1 |
| 7 | A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population显示文摘The Psychiatric Genomics Consortium(PGC)has recently identified 10 potential functional coding variants for schizophrenia.However,how these coding variants confer schizophrenia risk remains largely unknown.Here,we investigate the associations between eight potential functional coding variants identified by PGC and schizophrenia in a large Han Chinese sample(n=4022 cases and 9270 controls).Among the eight tested single nucelotide polymorphisms(SNPs),rs3617(a missense variant,p.K315 Q in the ITIH3 gene)showed genome-wide significant association with schizophrenia in the Han Chinese population(P=8.36×10-16),with the same risk allele as in PGC.Interestingly,rs3617 is located in a genomic region that is highly evolutionarily conserved,and its schizophrenia risk allele(C allele)was associated with lower ITIH3 mRNA and protein expression.Intriguingly,mouse neural stem cells stably overexpressing ITIH3 with different alleles of rs3617 exhibited significant differences in proliferation,migration,and differentiation,suggesting the impact of rs3617 on neurodevelopment.Subsequent transcriptome analysis found that the differentially expressed genes in neural stem cells stably overexpressing different alleles of rs3617 were significantly enriched in schizophrenia-related pathways,including cell adhesion,synapse assembly,MAPK and PI3 K-AKT pathways.Our study provides convergent lines of evidence suggesting that rs3617 in ITIH3 likely affects protein function and neurodevelopment and thereby confers risk of schizophrenia. | Kaiqin Li Yifan Li Junyang Wang Yongxia Huo Di Huang Shiwu Li Jiewei Liu Xiaoyan Li Rong Liu Xiaogang Chen Yong-Gang Yao Ceshi Chen Xiao Xiao Ming Li Xiong-Jian Luo | 2020 | Journal of Genetics and Genomics2020，47，5： | 1 |
| 8 | Energy-absorbing porous materials:Bioinspired architecture and fabrication显示文摘Energy-absorbing materials are widely used in transportations,sports,and the military applications.Particularly,porous materials,including natural and artificial materials,have attracted tremendous attentions due to their light weight and excellent energy absorption capability.This review summarizes the recent progresses in the natural and artificial energy-absorbing porous materials.First,we review the typical natural porous materials including cuttlebone,bighorn sheep horn,pomelo peel,and sunflower stem pith.The architectures,energy absorption abilities,and mechanisms of these typical natural materials and their bioinspired materials are summarized.Then,we provide a review on the fabrication methods of artificial energy-absorbing porous materials,such as conventional foaming and three-dimensional(3D)printing.Finally,we address the challenges and prospects for the future development of energy-absorbing porous materials.More importantly,our review provides a direct guidance for the design and fabrication of energy-absorbing porous materials required for various engineering applications. | Junheng Zhao Meng Li Jiewei Chen Weiwei Gao Hao Bai | 2024 | Nano Research2024，17，2： | 1 |
| 9 | Genome-wide analysis and identification of HAK potassium transporter gene family in maize (Zeamays L.)显示文摘 | Zhongbao Zhang Jiewei Zhang Yajuan Chen Ruifen Li Hongzhi Wang Jianhua Wei | 2012 | Molecular Biology Reports2012，，8： | 1 |
| 10 | Applications of metal-organic frameworks in heterogeneous supramolecular catalysis 显示文摘 | Liu Jiewei Chen Lianfen Cui Hao | 2014 | Chem Soc Rev2014，43，16： | 1 |
| 11 | Relationship between Renying pulse augmentation index and Cunkou pulse condition in different blood pressure groups显示文摘OBJECTIVE: To explore the relationship between Renying pulse (carotid) augmentation index (AI) and Cunkou pulse condition in different blood pressure groups, and the clinical significance of Renying and Cunkou pulse parameters to reflect vascular function.METHODS:Eighty-sixpatients with essential hypertension (EH) and 52 individuals with normal blood pressure(control group) between September 2010 and January 2012 were included in thisstudy.Renying pulse AI was examined by a new diagnostic tool(ALOKA ProSound Alpha 10) — wave intensity (WI) that is calculated as the product of the derivatives of the simultaneously recorded blood pressure changes(dP/dt) and blood-flow-velocity changes(dU/dt), while Cunkou pulse condition was detected by DDMX-100 Pulse Apparatus inboth EH and control groups. A multifactorial correlation analysis was performed for data analysis.RESULTS: After adjustingfor potentialconfoundingvariables,intheEHgroup,AIwaspositivelycorrelated with t5, w2/t(rt5=0.225, P<0.05; rw2/t=0.230, P<0.05)and negatively correlated with h5,h5/h1 and w2(rh5=﹣0.393,P<0.01;rh5/h1=﹣0.444,P<0.01;rw2=﹣0.389,P<0.01). In the control group, AI was positively correlated with t3, t4, t5 and w1(rt3=0.595, P<0.01; rt4=0.292, P<0.05; rt5=0.318, P<0.05; rw1=0.541, P<0.01)and negatively correlated with h1,h2,h3,AdandA(rh1=﹣0.368,P<0.05;rh2=﹣0.330,P<0.05;rh3=﹣0.327, P<0.05; rAd=﹣0.322, P<0.05; rA=﹣0.410, P<0.01). In the total sample group(EH plus control group, n=138), AI was positively correlated with t, t5, w1 and w2/t(rt=0.257,P<0.01;rt5=0.266,P<0.01;rw1=0.184,P<0.05; rw2/t=0.210, P<0.05) and negatively correlated with h5, h5/h1, w2 and Ad(rh5=﹣0.230, P<0.01; rh5/h1=﹣0.218, P<0.05; rw2=﹣0.267, P<0.01; rAd=﹣0.246,P<0.01). Multiple linear regression analysis was carried out to model the relationship(F=7.887, P<0.001).CONCLUSION:Renying pulse AI can effectively predict arterial stiffness in synchrony with the manifestations of Cunkou pulse in elderly patients with hypertension. Cunkou pulse apparatus is a valuable tool for evaluating AI in clinical practice. The close correlations reported above reflect the holistic concept of Traditional Chinese Medicine. | Jiewei Luo Xingyu Zheng Zijing Hu Jing Wu Shichao Wei Zhencheng Ye Weiji Chen Ning Lin Jianwei Li | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 1 |
| 12 | Crypto primitive of MOCVD MoS_(2) transistors for highly secured physical unclonable functions显示文摘Physically unclonable crypto primitives have potential applications for anti-counterfeiting,identification,and authentication,which are clone proof and resistant to variously physical attack.Conventional physical unclonable function(PUF)based on Si complementary metal-oxide-semiconductor(CMOS)technologies greatly suffers from entropy loss and bit instability due to noise sensitivity.Here we grow atomically thick MoS2 thin film and fabricate field-effect transistors(FETs).The inherently physical randomness of MoS2 transistors from materials growth and device fabrication process makes it appropriate for the application of PUF device.We perform electrical characterizations of MoS2 FETs,collect the data from 448 devices,and generate PUF keys by splitting drain current at specific levels to evaluate the response performance.Proper selection of splitting threshold enables to generate binary,ternary,and double binary keys.The generated PUF keys exhibit good randomness and uniqueness,providing a possibility for harvesting highly secured PUF devices with two-dimensional materials. | Bangjie Shao Tsz Hin Choy Feichi Zhou Jiewei Chen Cong Wang Yong Ju Park Jong-Hyun Ahn Yang Chai | 2021 | Nano Research2021，14，6： | 1 |
| 13 | Applications of metal-organic framework composites in CO_(2) capture and conversion显示文摘Reliable technologies for CO_(2) capture and conversion(C3) are of vital importance for the establishment of a sustainable society.Metal-organic framework(MOF) composites have shown their compelling potentials for C3 due to the plentiful reticular chemistry of MOF structures and the synergistic catalysis between MOFs and the functional guests.This review focuses on the syntheses and catalytic applications towards C3 of MOF composites,which is divided into three sections.The first section gives a brief introduction about synthetic strategies of MOF composites.The second section discusses the recent progress of MOF composites in C3,including CO_(2) chemical fixation,hydrogenation,photoreduction,electro reduction and photoelectro reduction.The third section summarizes the challenges and future prospects of MOF composites for C3.We hope that this review cannot only provide an inspiration for the rational design of MOF composites for C3,but also stimulate more and more research works in this emerging area. | Jiewei Liu Chunying Chen Kun Zhang Li Zhang | 2021 | Chinese Chemical Letters2021，32，2： | 1 |
| 14 | Methylseleninic Acid on The Apoptosis Induction and Invasion Inhibition in Human High-Meta-static Large Cell Lung Cancer Cell Line L9981显示文摘Background and Objective Lung cancer, which has been proved to have fastest increasing rate of morbidity and mortality, appears to be one of the most dangerous malignant tumor that | Jiewei LIU Yu FAN Li MA Jun CHEN Sen WEI Zhigang LI Hongyu LIU Haisu WAN Zhihao WU Qinghua ZHOU | 2009 | 中国肺癌杂志2009，12，6： | 0 |
| 15 | Alloy-buffer-controlled van der Waals epitaxial growth of aligned tellurene显示文摘Group-VI elemental two-dimensional(2D)materials(e.g.,tellurene(Te))have unique crystalline structures and extraordinarily physical properties.However,it still remains a great challenge to controllably grow 2D Te with good repeatability,uniformity,and highly aligned orientation using vapor growth method.Here,we design a Cu foil-assisted alloy-buffer-controlled growth method to epitaxially grow aligned single-crystalline 2D Te on an insulating mica substrate.The in-situ formation of Cu-Te alloy plays a key role on 2D Te growth,alleviating the spatial and temporal non-uniformity of precursor in conventional vapor deposition process.Through transmission electron microscopy(TEM)analysis combined with theoretical calculations,we unveil that the alignment growth of Te in the[110]direction is along the[600]direction of mica,owing to the small lattice mismatch(0.15%)and strong binding strength.This work presents a method to grow aligned high-quality 2D Te in a controllable manner. | Cong Wang Chao Xu Xuyun Guo Ning Zhang Jianmin Yan Jiewei Chen Wei Yu Jing-Kai Qin Ye Zhu Lain-Jong Li Yang Chai | 2022 | Nano Research2022，15，6： | 0 |
| 16 | Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission显示文摘Dear Editor,Dynamins and dynamin-related proteins(DRPs)constitute a large superfamily of GTPases throughout animal,plant,and bacteria and play essential roles in core cellular processes(Praefcke and McMahon,2004).Plant specific dynamin-related subfamilies share essential functions with those in mammalian cell,e.g.clarthrinmediated endocytosis and fission of mitochondria. | Liming Yan Yuanyuan Ma Yuna Sun Jian Gao Xiaoyue Chen Jiewei Liu Congwan Wang Zihe Rao Zhiyong Lou | 2011 | Journal of Molecular Cell Biology2011，3，6： | 0 |
| 17 | Designing novel thin film polycrystalline solar cells for high efficiency:sandwich CIGS and heterojunction perovskite显示文摘Heterojunction and sandwich architectures are two new-type structures with great potential for solar cells.Specifically,the heterojunction structure possesses the advantages of efficient charge separation but suffers from band offset and large interface recombination;the sandwich configuration is favorable for transferring carriers but requires complex fabrication process.Here,we have designed two thin-film polycrystalline solar cells with novel structures:sandwich CIGS and heterojunction perovskite,referring to the advantages of the architectures of sandwich perovskite(standard)and heterojunction CIGS(standard)solar cells,respectively.A reliable simulation software wxAMPS is used to investigate their inherent characteristics with variation of the thickness and doping density of absorber layer.The results reveal that sandwich CIGS solar cell is able to exhibit an optimized efficiency of 20.7%,which is much higher than the standard heterojunction CIGS structure(18.48%).The heterojunction perovskite solar cell can be more efficient employing thick and doped perovskite films(16.9%)than these typically utilizing thin and weak-doping/intrinsic perovskite films(9.6%).This concept of structure modulation proves to be useful and can be applicable for other solar cells. | Tianyue Wang Jiewei Chen Gaoxiang Wu Dandan Song Meicheng Li | 2017 | Journal of Semiconductors2017，38，1： | 0 |
| 18 | Surface BrØnsted-Lewis dual acid sites for high-efficiency dinitrogen photofixation in pure water显示文摘As is known to all, nitrogen not only plays an important role in the industrial development of human society but also plays an important part in the proteins that constitute the essence of life[1]. In 1910, the Haber-Bosch process was first used to synthesize ammonia. | Cai Chen Jiewei Chen Zhiyuan Wang Fei Huang Jian Yang Yunteng Qu Kuang Liang Xiao Ge Yanggang Wang Hui Zhang Yuen Wu | 2022 | Journal of Energy Chemistry2022，31，4： | 0 |
| 19 | Exploration of the oxygen transport behavior in non-precious metal catalyst-based cathode catalyst layer for proton exchange membrane fuel cells显示文摘High cost has undoubtedly become the biggest obstacle to the commercialization of proton exchange membrane fuel cells(PEMFCs),in which Pt-based catalysts employed in the cathodic catalyst layer(CCL)account for the major portion of the cost.Although nonprecious metal catalysts(NPMCs)show appreciable activity and stability in the oxygen reduction reaction(ORR),the performance of fuel cells based on NPMCs remains unsatisfactory compared to those using Pt-based CCL.Therefore,most studies on NPMC-based fuel cells focus on developing highly active catalysts rather than facilitating oxygen transport.In this work,the oxygen transport behavior in CCLs based on highly active Fe-N-C catalysts is comprehensively explored through the elaborate design of two types of membrane electrode structures,one containing low-Pt-based CCL and NPMCbased dummy catalyst layer(DCL)and the other containing only the NPMC-based CCL.Using Zn-N-C based DCLs of different thickness,the bulk oxygen transport resistance at the unit thickness in NPMC-based CCL was quantified via the limiting current method combined with linear fitting analysis.Then,the local and bulk resistances in NPMC-based CCLs were quantified via the limiting current method and scanning electron microscopy,respectively.Results show that the ratios of local and bulk oxygen transport resistances in NPMCbased CCL are 80%and 20%,respectively,and that an enhancement of local oxygen transport is critical to greatly improve the performance of NPMC-based PEMFCs.Furthermore,the activity of active sites per unit in NPMCbased CCLs was determined to be lower than that in the Pt-based CCL,thus explaining worse cell performance of NPMC-based membrane electrode assemblys(MEAs).It is believed that the development of NPMC-based PEMFCs should proceed not only through the design of catalysts with higher activity but also through the improvement of oxygen transport in the CCL. | Shiqu CHEN Silei XIANG Zehao TAN Huiyuan LI Xiaohui YAN Jiewei YIN Shuiyun SHEN Junliang ZHANG | 2023 | Frontiers in Energy2023，17，1： | 0 |
| 20 | 人工智能白内障协同管理的通用平台显示文摘目的:建立和验证一个涉及多级临床场景的白内障协作通用的人工智能(artificial intelligence,AI)管理平台,探索基于AI的医疗转诊模式,以提高协作效率和资源覆盖率。方法:训练和验证的数据集来自中国AI医学联盟,涵盖多级医疗机构和采集模式。使用三步策略对数据集进行标记:1)识别采集模式;2)白内障诊断包括正常晶体眼、白内障眼或白内障术后眼;3)从病因和严重程度检测需转诊的白内障患者。此外,将白内障AI系统与真实世界中的居家自我监测、初级医疗保健机构和专科医院等多级转诊模式相结合。结果:通用AI平台和多级协作模式在三步任务中表现出可靠的诊断性能:1)识别采集模式的受试者操作特征(receiver operating characteristic curve,ROC)曲线下面积(area under the curve,AUC)为99.28%~99.71%);2)白内障诊断对正常晶体眼、白内障或术后眼,在散瞳-裂隙灯模式下的AUC分别为99.82%、99.96%和99.93%,其他采集模式的AUC均>99%;3)需转诊白内障的检测(在所有测试中AUC>91%)。在真实世界的三级转诊模式中,该系统建议30.3%的人转诊,与传统模式相比,眼科医生与人群服务比率大幅提高了10.2倍。结论:通用AI平台和多级协作模式显示了准确的白内障诊断性能和有效的白内障转诊服务。建议AI的医疗转诊模式扩展应用到其他常见疾病和资源密集型情景当中。 | WU Xiaohang HUANG Yelin LIU Zhenzhen LAI Weiyi LONG Erping ZHANG Kai JIANG Jiewei LIN Duoru CHEN Kexin YU Tongyong WU Dongxuan LI Cong CHEN Yanyi ZOU Minjie CHEN Chuan ZHU Yi GUO Chong ZHANG Xiayin WANG Ruixin YANG Yahan XIANG Yifan CHEN Lijian LIU Congxin XIONG Jianhao GE Zongyuan WANG Dingding XU Guihua DU Shaolin XIAO Chi WU Jianghao ZHU Ke NIE Danyao XU Fan LV Jian CHEN Weirong LIU Yizhi 林浩添 无 王厚硕(审校) 罗明杰(审校) | 2023 | 眼科学报2023，38，10： | 0 |
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