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| 1 | Reactive lymphoid hyperplasia of the liver:Perinodular enhancement on contrast-enhanced computed tomography and magnetic resonance imaging显示文摘We report the case of a 69-year-old woman with reactive lymphoid hyperplasia(RLH) of the liver.She underwent partial hepatectomy under a preoperative diagnosis of hepatocellular carcinoma; however,histopathological analysis revealed RLH.The liver nodule showed the imaging feature of perinodular enhancement in the arterial dominant phase on contrast-enhanced computed tomography and magnetic resonance imaging,which could be a useful clue for identifying RLH in the liver.Histologically,the perinodular enhancement was compatible with prominent sinusoidal dilatation surrounding the liver nodule. | Tetsuo Sonomura Shinpei Anami Taizo Takeuchi Motoki Nakai Shinya Sahara Hirohiko Tanihata Kazuki Sakamoto Morio Sato | 2015 | World Journal of Gastroenterology2015，21，21： | 7 |
| 2 | Treatment strategy for hepatocellular carcinoma: expanding the indications for radiofrequency ablation显示文摘 | Ryosuke Tateishi Shuichiro Shiina Takamasa Ohki Takahisa Sato Ryota Masuzaki Jun Imamura Eriko Goto Tadashi Goto Hideo Yoshida Shuntaro Obi Shinpei Sato Fumihiko Kanai Haruhiko Yoshida Masao Omata | 2009 | Journal of Gastroenterology2009，，19： | 1 |
| 3 | Application of diamond films from CO-H2 plasma to tool blade coating显示文摘 | Yukio Saito Kouji Sato Shinpei Matuda Hideomi Koinuma | 1991 | Journal of Materials Science1991，，11： | 1 |
| 4 | Application of diamond films from CO - H2 plasma to tool blade coating显示文摘 | Yukio Saito Kouji Sato Shinpei Matuda | 1991 | Journal of materials science1991，26，： | 1 |
| 5 | Hepatic sarcoidosis found as a small liver SOL in a patient with type C cirrhosis显示文摘 | Atsuko Takai Hirotoshi Fijikawa Yumi Kawashima Eriko Kitazawa Hirotsugu Watabe Shinpei Sato Masanao Matsushita Hiroshi Miyakawa | 2005 | Journal of Gastroenterology2005，，7： | 1 |
| 6 | A Randomized Controlled Trial of Radiofrequency Ablation With Ethanol Injection for Small Hepatocellular Carcinoma显示文摘 | Shuichiro Shiina Takuma Teratani Shuntaro Obi Shinpei Sato Ryosuke Tateishi Tomonori Fujishima Takashi Ishikawa Yukihiro Koike Haruhiko Yoshida Takao Kawabe Masao Omata | 2005 | Gastroenterology2005，，1： | 1 |
| 7 | Relationship between outcomes and relative dose intensity of lenvatinib treatment in patients with advanced hepatocellular carcinoma显示文摘Background and aims:Lenvatinib(LEN)is a newly developed tyrosine kinase inhibitor,and is approved as a first-line treatment for advanced hepatocellular carcinoma(HCC)in Japan.This retrospective multi-center study investigated the effect of the relative dose intensity(RDI)of LEN on response rate,progression-free survival(PFS),and overall survival(OS).Methods:This retrospective study enrolled 123 patients with advanced HCC who were treated with LEN at six hospitals in Japan between March 2018 and December 2019.These patients were divided into two groups:RDI≥70%(RDI 70 group,N=70)or RDI<70%(control group,N=53)in the first 30 days.The following data were compared between groups:patient backgrounds,adverse events,treatment out-comes,PFS,and OS.PFS and OS were analyzed using the Kaplan-Meier method,followed by the log-rank test.To identify significant factors that contributed to response,PFS,and OS,multivariate analysis was performed using factors for which P-values were<0.10 in univariate analysis.Results:The proportion of patients with Child-Pugh class 5A was significantly greater in the RDI 70 group than that in the control group(64.3%vs.28.3%,P<0.01).Dose interruption due to adverse events was significantly more common in the control group.The response rate was significantly higher in the RDI 70 group than that in the control group(35.7%vs.11.3%,P<0.01).Median PFS was significantly longer in the RDI 70 group(9.4 vs.4.7 months,P<0.01).Multivariate analysis showed that RDI≥70%(hazard ratio(HR)=0.55,P=0.025),hypertension grade≥2(HR=0.47,P=0.019),and response(HR=0.52,P=0.033)were independently associated with improved PFS.Median OS was also significantly longer in the RDI 70 group(20.0 vs.13.3 months,P=0.045).Multivariate analysis showed that female sex(HR=0.33,P=0.034)and disease control(HR=0.31,P<0.01)were independently associated with improved OS.RDI≥70%was not statistically significant in multivariate analysis.Conclusions:Our study revealed the importance of achieving RDI≥70%in the first 30 days of treatment to maximize the effects of LEN。 | Takamasa Ohki Koki Sato Mayuko Kondo Eriko Goto Takahisa Sato Yuji Kondo Masatoshi Akamatsu Shinpei Sato Hideo Yoshida Yukihiro Koike Shuntaro Obi | 2020 | Liver Research2020，4，4： | 1 |
| 8 | Risk factors for recurring hepatocellular carcinoma differ according to infected hepatitis virus—An analysis of 236 consecutive patients with a single lesion显示文摘 | Yukihiro Koike Yasushi Shiratori Shinpei Sato Shuntaro Obi Takuma Teratani Masatoshi Imamura Keisuke Hamamura Yasuo Imai Haruhiko Yoshida Shuichiro Shiina Masao Omata | 2000 | Hepatology2000，，6： | 1 |
| 9 | Application of diamond films from CO-H2 plasma to tool blade coating 显示文摘 | Yukio Saito Kouji Sato Shinpei Matuda | 1991 | Journal of materials science1991，26，： | 1 |
| 10 | Application of Diamond Films from CO-H2 Plasma to Tool Blade Coating 显示文摘 | Yukio Saito Kouji Sato Shinpei Matuda | 1991 | Journal of materials science1991，26，： | 1 |
| 11 | A Randomized Controlled Trial of Radiofrequency Ablation With Ethanol Injection for Small Hepatocellular Carcinoma显示文摘 | Shuichiro Shiina Takuma Teratani Shuntaro Obi Shinpei Sato Ryosuke Tateishi Tomonori Fujishima Takashi Ishikawa Yukihiro Koike Haruhiko Yoshida Takao Kawabe Masao Omata | 2005 | Gastroenterology2005，，1： | 1 |
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