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| 1 | Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer显示文摘AIM:To investigate the association between adiponectin levels and risk of colorectal adenoma and cancer (early and advanced).METHODS: A cross-sectional study in a cohort of hospital-based patients was conducted between January 2004 and March 2006 at Yamagata University Hospital. Male subjects, who had colorectal tumors detected by endoscopic examination, were enrolled according to inclusion and exclusion criteria. Based on the T factor of the TNM system, intraepithelial carcinoma and submucosally invasive carcinoma were def ined as early cancer, and invasion into the muscularis propria or deeper was defined as advanced cancer. The plasma levels of glucose, insulin, total cholesterol, triglyceride, high sensitivity C-reactive protein, insulin like growth factor (IGF)-1, IGF binding protein-3, adiponectin, leptin, and resistin were measured. Each factor level was designated low or high, and the risk of adenoma or cancer was estimated by univariate and multivariate logistic regression analysis.RESULTS: We enrolled 124 male subjects (47 with adenoma, 34 with early cancer, 17 with advanced cancer, and 26 without tumors as controls). In patients with adenoma, high triglyceride and low adiponectin were associated with a significant increase in the odds ratio (OR) by univariate analysis. Only a low adiponectin level was related to increased adenoma risk, with an adjusted OR for low level (<11 μg/mL) to high (≥11 μg/mL) of 5.762 (95% confidence interval (CI):1.683-19.739, P=0.005). In the patients with early cancer, high body mass index, high triglyceride, and low adiponectin were associated with a significant increase in OR in univariate analysis. Imultivariate analysis, only low adiponectin was significantly associated with early cancer, with an adjusted OR of 4.495 (95% CI:1.090-18.528, P=0.038). However, in patients with advanced cancer, low adiponectin was not recognized as a significant risk factor for advanced cancer.CONCLUSION: A decreased level of adiponectin is strongly associated with an increased risk of colorectal adenoma and early cancer. These data call for further investigation, including a controlled prospective study. | Sayaka Otake Hiroaki Takeda Shoichiro Fujishima Tadahisa Fukui Tomohiko Orii Takeshi Sato Yu Sasaki Shoichi Nishise Sumio Kawata | 2010 | World Journal of Gastroenterology2010，16，10： | 14 |
| 2 | Social Language Learning Spaces: Affordances in a Community of Learners显示文摘本文以民族志调查的形式报告了日本一所大学内分别以英语和日语为母语的外语学习者参加社会学习空间在语言和社会文化方面的可用特性 (affordances)。社会学习空间是指可让学生聚在一起在非正式的环境下互相学习的设施。为了探讨这种环境下的社会学习动力,我们进行了一项纵向民族志调查。数据资料主要来自对学生和管理员的访谈,辅以对参与者的观察。从生态和实践社群的视角对数据资料进行专题分析 (thematic analysis) 可以看出学习者社群的出现,以及可用特性与突现社群 (emergent community) 之间的密切相关性。本文报告了与引致语言学习机会的可用特性相关的调查结果,这些可用特性与支持学习者社群发展的条件之间的关系,以及学习者自主性在前两个相互关联的现象中所起的作用。 | Garold MURRAY Naomi FUJISHIMA | 2013 | Chinese Journal of Applied Linguistics2013，36，1： | 5 |
| 3 | Hierarchical structures hydrogel evaporator and superhydrophilic water collect device for efficient solar steam evaporation显示文摘Efficient light absorption and trapping are of vital importance for the solar water evaporation by hydrogel-based photothermal conversion materials.Conventional strategies are focused on the development of the composition and structure of the hydrogers internal network.In our point of view,the importance of the surface structure of hydrogel has usually been underestimated or ignored.Here inspired by the excellent absorbance and water transportation ability of biological surface structure,the hierarchical structured hydrogel evaporators(HSEs)increased the light absorption,trapping,water transportation and water-air interface,which is the beneficial photothermal conversion and water evaporation.The HSEs showed a rapid evaporation rate of 1.77 kg·m^(-2)·h^(-1)at about 92%energy efficiency under one sun(1 kW·m^(-2)).Furthermore,the superhydrophilic window device was used in this work to collect the condensed water,which avoids the light-blocking caused by the water mist formed by the small droplets and the problem of the droplets stick on the device dropping back to the bulk water.Integrated with the excellent photothermal conversion hydrogel and superhydrophilic window equipment,this work provides efficient evaporation and desalination of hydrogel-based solar evaporators in practical large-scale applications. | Wenwei Lei Sovann Khan Lie Chen Norihiro Suzuki Chiaki Terashima Kesong Liu Akira Fujishima Mingjie Liu | 2021 | Nano Research2021，14，4： | 4 |
| 4 | IgG4-unrelated type 1 autoimmune pancreatitis显示文摘A 50-year-old male was referred to our hospital for the evaluation of hyperproteinemia.Fluorodeoxyglucose positron emission tomography revealed high fluorodeoxyglucose uptake in the pancreas,bilateral lacrimal glands,submandibular glands,parotid glands,bilateral pulmonary hilar lymph nodes,and kidneys.Laboratory data showed an elevation of hepatobiliary enzymes,renal dysfunction,and remarkably high immunoglobulin(Ig) G levels,without elevated serum IgG4.Abdominal computed tomography revealed swelling of the pancreatic head and bilateral kidneys.Endoscopic retrograde cholangiopancreatography showed an irregular narrowing of the main pancreatic duct in the pancreatic head and stricture of the lower common bile duct.Histological examination by endoscopic ultrasonography-guided fine-needle aspiration revealed findings of lymphoplasmacytic sclerosing pancreatitis without IgG4-positive plasma cells.Abnormal laboratory values and the swelling of several organs were improved by the treatment with steroids.The patient was diagnosed as having type 1 autoimmune pancreatitis(AIP) based on the International Consensus Diagnostic Criteria.Therefore,we encountered a case of compatible type 1 AIP without elevated levels of serum IgG4 or IgG4-positive plasma cells.This case suggests that AIP phenotypes are not always associated with IgG4. | Eriko Nakano Atsushi Kanno Atsushi Masamune Naoki Yoshida Seiji Hongo Shin Miura Tetsuya Takikawa Shin Hamada Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Keisuke Nakayama Fumiyoshi Fujishima Tooru Shimosegawa | 2015 | World Journal of Gastroenterology2015，21，33： | 3 |
| 5 | Titanium dioxide photocatalysis显示文摘 | Akira Fujishima Tata N. Rao Donald A. Tryk | 2000 | Journal of Photochemistry & Photobiology C: Photochemistry Reviews2000，，1： | 3 |
| 6 | Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria显示文摘 | Atsushi Kanno Kazuyuki Ishida Shin Hamada Fumiyoshi Fujishima Jun Unno Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Atsushi Masamune Kennichi Satoh Kenji Notohara Tooru Shimosegawa | 2012 | Gastrointestinal Endoscopy2012，，3： | 3 |
| 7 | Electrochemical photolysis of water at a semiconductor electrode 显示文摘 | Fujishima A Honda K | 1972 | Nature1972，238，5358： | 2 |
| 8 | 显示文摘 | Fujishima A Honda | 1972 | Nature1972，238，： | 2 |
| 9 | Trabeculectomy with the use of amniotic membrane for uncontrollable glaucoma 显示文摘 | Fujishima H | 1998 | Ophthalmic Surg Lasers1998，29，5： | 2 |
| 10 | Electrochemical photolysis of water at a semiconductor electrode显示文摘 | FUJISHIMA A HONDA K | 1972 | Nature1972，238，： | 2 |
| 11 | Recent topics in photoelectrochemistry: achievements and future prospects 显示文摘 | Tryk D A Fujishima A Honda K | 2000 | Electrochim Acta2000，45，1516： | 2 |
| 12 | Titanium dioxide photocatalysis显示文摘 | Fujishima A Rao T N Tryk D A | 2000 | J Photochem Photobio C:Photochem Rev2000，，1： | 2 |
| 13 | TiO 2 photocatalysis: Design and applications显示文摘 | Kazuya Nakata Akira Fujishima | 2012 | Journal of Photochemistry & Photobiology, C: Photochemistry Reviews2012，，3： | 2 |
| 14 | Titanium dioxide photocatalysis显示文摘 | FUJISHIMA A RAO T N TRYK D A | 2000 | J Photochem Photobiol C: Photochem Rev2000，1，1： | 2 |
| 15 | Photoelectrochemical properties of TiO 2 photocatalyst and its applications for environmental purification显示文摘 | Tsuyoshi Ochiai Akira Fujishima | 2012 | Journal of Photochemistry & Photobiology C: Photochemistry Reviews2012，，4： | 2 |
| 16 | Electrochemical photolysis of water at a semiconductor electrode显示文摘 | Fujishima A Hondo K | 1972 | Nature1972，，37： | 1 |
| 17 | Proliferative activity ofmixed hyper-plastic adenomatous polyp/serrated adenoma in the large intestinemeasured by PCNA(proliferating cell nuclear antigen)显示文摘 | Fujishima K | 1996 | J Gastroenterol1996，31，3： | 1 |
| 18 | Fabrication of high -- quality opal films with controllable thickness 显示文摘 | Gu Z Z Fujishima A Sato S | 2002 | Chem Mater2002，14，2： | 1 |
| 19 | Electrochemistry photolysis of water at semi-conduct electrode 显示文摘 | | 1972 | Nature1972，238，37： | 1 |
| 20 | Nature显示文摘 | Fujishima A Honda K | 1972 | 238: 371972，238，： | 1 |
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