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| 1 | The development of perturbation model for fringe field in Open XAL and its application in beam commissioning of CSNS显示文摘Background The China Spallation Neutron Source(CSNS)accelerator employs Open XAL as the control software in beam commissioning.The main magnets of CSNS/RCS have serious fringe field effect;however,there is not corresponding model for fringe field in Open XAL.Purpose The purpose is to develop a suitable model for fringe field and append to the online model of Open XAL.Methods On the basis of the requirements of beam commissioning and model features of Open XAL,a perturbation model was developed to correct the effect of fringe field.Results The comparison of the parameters calculated by slice model with the values obtained from Open XAL with perturbation model showed the validity of the model.Furthermore,with the response matrix method,the values obtained from Open XAL with perturbation model were very close to the measured response matrices,which showed the accuracy of the model.Conclusion The perturbation model is effective for correcting the fringe field effect in Open XAL. | Xiaohan Lu Jianliang Chen Shouyan Xu Ming-Yang Huang Yuwen An Sheng Wang | 2018 | Radiation Detection Technology and Methods2018，2，2： | 1 |
| 2 | Enhancer RNAs: A missing regulatory layer in gene transcription显示文摘Enhancers and super-enhancers exert indispensable roles in maintaining cell identity through spatiotemporally regulating gene transcription.Meanwhile,active enhancers and super-enhancers also produce transcripts termed enhancer RNAs(eRNAs) from their DNA elements.Although enhancers have been identified for more than 30 years,widespread transcription from enhancers are just discovered by genome-wide sequencing and considered as the key to understand longstanding questions in gene transcription.RNA-transcribed enhancers are marked by histone modifications such as H3K4m1/2 and H3K27Ac,and enriched with transcription regulatory factors such as LDTFs,P300,CBP,BRD4 and MED1.Those regulatory factors might constitute a Mega-Trans-like complex to potently activate enhancers.Compared to mRNAs,eRNAs are quite unstable and play roles at local.Functionally,it has been shown that e RNAs promote formation of enhancer-promoter loops.Several studies also demonstrated that eRNAs help the binding of RNA polymerase II(RNAPII) or transition of paused RNAPII by de-association of the negative elongation factor(NELF) complex.Nevertheless,these proposed mechanisms are not universally accepted and still under controversy.Here,we comprehensively summarize the reported findings and make perspectives for future exploration.We also believe that super-enhancer derived RNAs(seRNAs) might be informative to understand the nature of super-enhancers. | Renfang Mao Yuanyuan Wu Yue Ming Yuanpei Xu Shouyan Wang Xia Chen Xiaoying Wang Yihui Fan | 2019 | Science China(Life Sciences)2019，62，7： | 1 |
| 3 | Determining fabrication orientation for rapid prototyping with stereolithography apparatus显示文摘 | LAN Poting CHOU Shouyan CHEN Linlin | 1997 | Computer-Aided Design1997，29，1： | 1 |
| 4 | RASAL2 acts as a tumor suppressor in cervical cancer cells显示文摘This study was designed to investigate the roles of RASAL2 in cervical cancer(CC).Methods:Fifty-four CC tissues and 33 adjacent tissues were obtained from CC patients admitted to our hospital between March 2012 and June 2014.Real-time polymerase chain reaction and western blotting were performed to analyze the expression of RASAL2 mRNA and protein in these tissues,CC cell lines,and normal cervical cells.Over-expression and silencing of RASAL2 were induced after transfection,and the migration,invasion,and proliferation of the CC cell lines were examined.Results:RASAL2 mRNA and protein expressions were significantly down-regulated in CC tissues and cell lines than in adjacent tissues and normal cervical cells,respectively.While low RASAL2 expression correlated with advanced stage and metastasis of CC,its over-expression significantly inhibited proliferation and metastasis of CC cells and induced apoptosis.Under in vitro conditions,silencing of RASAL2 expression could significantly increase the proliferation,invasion,and migration of CC cells.Conclusion:RASAL2 functioned as a tumor suppressor in CC,and was down-regulated in CC tissue samples and cell lines. | LI CHEN FANGFANG LI SHOUYAN CAO XIA LI CHAO ZHOU SAI HAN YOUZHONG ZHANG | 2023 | BIOCELL2023，47，7： | 0 |
| 5 | Numerical study on the role of microwave-metal discharge in microwave pyrolysis of WPCBs显示文摘As a promising green technology,microwave heating is highlighted by its high efficiency and low consumption,especially in the fast pyrolysis treatment for e-waste recycling.Electric discharge induced by microwave-metal interaction plays a significant role in the process,and its contribution to heat generation is,however,always hard to define qualitatively through direct experiments.In this simulation,a microwave heating model featuring the pulsed microwave-metal(MW-m)discharge was designed in multi-dimensions,using COMSOL Multiphysics software,to emphatically probe the depth and extent of the hot-spot effect as well as its auxo-action on the pyrolysis process of waste printed circuit boards(WPCBs).The energy loss generated by MW-m discharge was added into the models in the form of a built-in fluctuating heat source,and it is found that at a relatively low microwave energy-to-heat conversion rate(31.5%,220.5 W),due to the unique thermal effect of microwave-metal discharge,it can achieve an ideal pyrolysis effect.Based on the results,the instantaneous heat by discharge is generated in the similar trend of radiation pulses,and the local temperature of discharge spots can reach more than 2000 K the instant the discharge occurs,shortening the overall pyrolysis from dozens of minutes to around 200 s. | Zhenyu Jiang Jing Sun Wenlong Wang Huacheng Zhu Jingwei Li Zhanlong Song Xiqiang Zhao Yanpeng Mao Shouyan Chen | 2021 | Waste Disposal and Sustainable Energy2021，3，3： | 0 |
| 6 | Neural-Network-Based Adaptive Finite-Time Control for a Two-Degree-of-Freedom Helicopter System With an Event-Triggering Mechanism显示文摘Helicopter systems present numerous benefits over fixed-wing aircraft in several fields of application.Developing control schemes for improving the tracking accuracy of such systems is crucial.This paper proposes a neural-network(NN)-based adaptive finite-time control for a two-degree-of-freedom helicopter system.In particular,a radial basis function NN is adopted to solve uncertainty in the helicopter system.Furthermore,an event-triggering mechanism(ETM)with a switching threshold is proposed to alleviate the communication burden on the system.By proposing an adaptive parameter,a bounded estimation,and a smooth function approach,the effect of network measurement errors is effectively compensated for while simultaneously avoiding the Zeno phenomenon.Additionally,the developed adaptive finite-time control technique based on an NN guarantees finitetime convergence of the tracking error,thus enhancing the control accuracy of the system.In addition,the Lyapunov direct method demonstrates that the closed-loop system is semiglobally finite-time stable.Finally,simulation and experimental results show the effectiveness of the control strategy. | Zhijia Zhao Jian Zhang Shouyan Chen Wei He Keum-Shik Hong | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，8： | 0 |
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