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46篇 您的检索式:作者名="Shucheng Wang"
    题名 作者 年代 出处 被引量
1Soil pH impact on microbial tetraether lipids and terrestrial input index (BIT) in China显示文摘The distributions of microbial tetraether lipids i.e. glycerol dialkyl glycerol tetraethers (GDGTs) were investigated in a variety of Chinese soils featured by a wide range of pH values in different climate zones. The bacterial branched GDGTs and archaeal isoprenoid GDGTs were found to be widely distributed in Chinese soils and their relative abundance was controlled primarily by soil pH. The bacterial bGDGTs usually dominate over archaeal iGDGTs in abundance when the soil pH is below 8.0. However archaeal iGDGTs become dominant and the abundance of halophilic archaea characterized by GDGT V without cyclopentyl ring increases dramatically in the alkaline soil with pH greater than 8.0. The relative abundance of archaeal iGDGTs to bacterial bGDGTs was defined here as RAI index. The RAI index decreases with elevated soil pH and a linear correlation is found between them indicating that the relative abundance of archaeal iGDGTs to bacterial bGDGTs increases with increased pH. The RAI index thus could be a novel proxy of the pH values of paleosol. The terrestrial input index BIT (Branched and Isoprenoid Tetraethers Index) decreases with increased soil pH suggesting that soil pH should be taken into consideration when the terrestrial contribution to marine sediments is estimated by BIT index. Moreover the TEX86 index cannot be used to reconstruct sea surface temperature in the sediments featured by a large terrestrial input.YANG Huan DING WeiHua WANG JinXiang JIN ChengSheng HE GangQiang QIN YangMin XIE ShuCheng 2012Science China Earth Sciences2012,55,2:19
2Spurious Thermoluminescence Characteristics of the Ediacaran Doushantuo Formation(ca. 635–551 Ma) and Its Implications for Marine Dissolved Organic Carbon Reservoir显示文摘The Ediacaran Doushantuo Formation(ca. 635–551 Ma) deposited immediately after the last Neoproterozoic glaciations and recorded the most prominent negative excursions of carbonate carbon isotopic composition(δ^(13)C_(carb)). These excursions have been interpreted as a result of widespread remineralization of a large dissolved organic carbon(DOC) reservoir in the Ediacaran deep oceans. However, there is no direct evidence so far found in rocks for the proposed DOC reservoir, which devalues such an interpretation. Here, we conducted a detailed study on the glow-curves characteristics and signal origins of spurious thermoluminescence(TL) of the Doushantuo Formation at Jiulongwan in Yangtze Gorges area, South China, through sequential tests under CO_2, N_2 and air. Spurious TL intensities for test samples before and after removing soluble organic matter via accelerated solvent extraction(ASE) are nearly identical. Further, significant positive correlation between the spurious TL intensity and total inorganic carbon(TIC) content(R^2=0.7) indicate that the Doushantuo spurious TL with the characteristic peak at 393.5 °C from the sequential test is chemiluminescence(CL) which is derived from the oxidation of a type of non-volatile organic matter strongly associated with carbonate mineral lattice(termed as 'X-OM'). A most likely explanation is that the X-OM is a type of dissolved organic matter which co-precipitated with carbonate minerals into sediments in the Ediacaran Doushantuo Ocean. Furthermore, a significant exponential negative correlation(R^2=0.55) is observed between the CL data and the isotopic difference between carbonate and coexisting bulk organic matter(i.e., Δ^(13)C_(carb-org), a proxy for remineralization degree of DOC reservoir in proposed DOC hypothesis), suggesting that the X-OM was derived from the oxidation of the DOC reservoir in the Ediacaran Ocean. We thus propose that the X-OM and its CL detected in our study may have recorded the evolution of the possible DOC reservoir in the Ediacaran Doushantuo Ocean. If this is correct, the stratigraphic variations of the CL intensity in the Doushantuo Formation at Jiulongwan support the pulsed oxidation of the DOC reservoir in the Ediacaran Ocean. Our findings indicate that the CL derived from the oxidation of non-volatile organic matter which is strongly associated with carbonate mineral lattices in rocks may provide a feasible approach for probing the evolution of DOC reservoir in the ancient oceans, thus likely provide direct geological evidence for the development of oceanic DOC reservoir in geological times.Haiyang Wang Chao Li Chaoyong Hu Shucheng Xie 2015Journal of Earth Science2015,26,6:12
3Geomicrobial functional groups:A window on the interaction between life and environments显示文摘Microbes are well-known for their great diversity and abundance in modern natural environments.They also are believed to pro-vide critical links among higher organisms and their associated environments.However,the low diversity of morphological fea-tures and structures of ancient microbes preserved in sediments and rocks make them difficult to identify and classify.This diffi-culty greatly hinders the investigation of geomicrobes throughout Earth history.Thus,most previous paleontological studies have focused on faunal and floral fossils.Here,geomicrobial functional groups(GFGs),or a collection of microbes featured in specific ecological,physiological or biogeochemical functions,are suggested to provide a way to overcome the difficulties of ancient mi-crobe investigations.GFGs are known for their great diversity in ecological,physiological and biogeochemical functions.In addi-tion,GFGs may be preserved as the biogeochemical,mineralogical and sedimentological records in sediments and rocks.We reviewed the functions,origins and identification diagnostics of some important GFGs involved in the elemental cycles of carbon,sulfur,nitrogen and iron.GFGs were further discussed with respect to their significant impacts on paleoclimate,sulfur chemistry of ancient seawater,nutritional status of geological environments,and the deposition of Precambrian banded iron formations.XIE ShuCheng YANG Huan LUO GenMing HUANG XianYu LIU Deng WANG YongBiao GONG YiMing XU Rana 2012Chinese Science Bulletin2012,57,1:11
4The fluctuating environment associated with the episodic biotic crisis during the Permo/Triassic transition:Evidence from microbial biomarkers in Changxing,Zhejiang Province显示文摘The environmental conditions and the biotic crisis during the Permo-Triassic (Tr/P) transition received increasing attention in the past decades. Presented herein are the molecular fossil records of cyano-bacteria and green sulfur bacteria,the base of the marine ecosystem,to highlight the episodic nature of both the environment and the biotic crisis during this critical period. At least two episodes of cyano-bacterial expansion are documented by 2-methylhopanes ranging from C28 to C32 in carbon number,indicative of the instable marine ecosystem and the fluctuant aquatic nutrients. Meanwhile,the index of 2-alkyl-1,3,4-trimethylbenzenes (biomarkers of green sulfur bacteria) and the ratio of pristane to phy-tane (Pr/Ph) witness the fluctuation of sedimentary environmental redox conditions. The above mo-lecular evidence suggests the occurrence of highly fluctuating environmental conditions during the Tr/P transition,which is consistent with,and probably the cause of,the multi-phased biotic crisis and the prolonged faunal recovery.HUANG XianYu JIAO Dan LU LiQiang XIE ShuCheng HUANG JunHua WANG YongBiao YIN HongFu WANG HongMei ZHANG KeXin LAI XuLong 2007Science China Earth Sciences2007,50,7:10
5Role of brain-derived neurotrophic factor and neuronal nitric oxide synthase in stress-induced depression显示文摘BACKGROUND: Accumulated evidence indicates an important role for hippocampal dendrite atrophy in development of depression, while brain-derived neurotrophic factor (BDNF) participates in hippocampal dendrite growth. OBJECTIVE: To discuss the role of BDNF and neuronal nitric oxide synthase (nNOS) in chronic and unpredictable stress-induced depression and the pathogenesis of depression. DESIGN, TIME AND SETTING: Randomized, controlled animal experiment. The experiment was carried out from October 2006 to May 2007 at the Department of Animal Physiology, College of Life Science, Shaanxi Normal University. MATERIALS: Thirty-seven male Sprague-Dawley rats weighing 250-300 g at the beginning of the experiment were obtained from Shaanxi Provincial Institute of Traditional Chinese Medicine (Xi'an, China). BDNF antibody and nNOS antibody were provided by Santa Cruz (USA). K252a (BDNF inhibitor) and 7-NI (nNOS inhibitor) were provided by Sigma (USA). METHODS: Animals were randomly divided into five groups: Control group, chronic unpredicted mild stress (CUMS) group, K252a group, K252a+7-NI group and 7-NI+CUMS group. While the Control, K252a and K252a+7-NI groups of rats not subjected to stress had free access to food and water, other groups of rats were subjected to nine stressors randomly applied for 21 days, with each stressor applied 2-3 times. On days 1, 7, 14 and 21 during CUMS, rats received microinjection of 1 μL of physiological saline in the Control and CUMS groups, 1 μL of K252a in the K252a group, 1 μL of K252a and 7-NI in the K252a+7-NI group, and 1 μL of 7-NI in the 7-NI+CUMS group. We observed a variety of alterations in sucrose preference, body weight change, open field test and forced swimming test, and observed the expression of BDNF and nNOS in rat hippocampus by immunohistochemistry; MAIN OUTCOME MEASURES: ① A variety of behavioral alterations of rats; ② The expression of BDNF and nNOS in rat hippocampus. RESULTS: Compared with the Control group, the behavior of the CUMS rats was significantly depressed, the expression of BDNF decreased (P < 0.01) but the expression of nNOS increased (P < 0.01). The behavior of rats given intra-hippocampal injection of BDNF inhibitor was significantly depressed and the expression of nNOS was significantly increased (P < 0.01). Intra-hippocampal injections of an nNOS inhibitor reversed the depression-like behavioral changes induced by CUMS or intra-hippocampal injection of BDNF inhibitor. CONCLUSION: CUMS induced a decrease in expression of BDNF and an increase in expression of NO in the hippocampus, which may lead to depression.Dan Wang Shucheng An 2008Neural Regeneration Research2008,3,4:8
6Dielectric barrier plasma dynamics for active aerodynamic flow control显示文摘The paper investigates the dynamics of a new multiple bipolar multiple Dielectric Barrier Discharges(DBD)actuator using in large-scale flow control.Particle image velocimetry experiments are performed to characteristic the effectiveness of the multiple bipolar DBD plasma actuator.The results show that the mutual interaction between the electrodes,one major disadvantage of traditional DBD characterized by reverse discharge can be entirely avoided,and a constantly accelerating electric wind velocity can be obtained by using the new multiple bipolar DBD plasma actuator.HAO JiangNan TIAN BaLin WANG YuLin SONG YaHui PAN ShuCheng LI WenFeng 2014Science China(Physics,Mechanics & Astronomy)2014,57,2:6
7Effect of wastewater composition on the calcium carbonate precipitation in upflow anaerobic sludge blanket reactors显示文摘Calcium carbonate often precipitates in anaerobic reactors treating wastewater with high calcium content.The aim of this paper is to study the effect of wastewater composition on calcium carbonate precipitation in upflow anaerobic sludge blanket(UASB)reactors.Two laboratory-scale UASB reactors were operated with calcium-containing influents using acetate and carbohydrate as substrate,respectively.There was an obvious accumulation of inorganic precipitate observed in the biogranules.Observations via scanning electron microscope(SEM)and energy dispersive spectroscopy(EDS)showed that the acclimated biogranules in the two reactors differed in microstructure.Calcium carbonate was found to have precipitated on the surface of acetate-degrading biogranules,but precipitated at the core of the carbohydrate-degrading biogranules.The results indicated that substrates had significant influence on the location of calcium carbonate precipitation in anaerobic granular sludge,which was expected due to the different methanogens distribution and pH gradient within the granular sludge degrading various substrates.Moreover,the location of calcium carbonate precipitation substantially affected the specific methanogenic activity(SMA)of the granular sludge.The SMA of the acetate-degrading biogranules dropped from 1.96 gCODCH4·gVSS^(–1)·d^(–1)to 0.61 gCODCH4·gVSS^(–1)·d^(–1)after 180-d of operation in the reactor.However,the SMA of the carbohydrate-degrading biogranules was not adversely affected by calcium carbonate precipitation.Shucheng YANG Yanling HE Yonghong LIU Charles CHOU Pengxiang ZHANG Dongqi WANG 2010Frontiers of Environmental Science & Engineering2010,4,2:6
8Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry显示文摘A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer(GC-MS/MS) for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans(PCDD/Fs) and dioxin-like polychlorinated biphenyls(DL-PCBs) in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level(10 pg mL^(-1) for 2,3,7,8-TCDD/F), as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5–200 ng mL^(-1) for PeCDD/F and 0.2–2000 ng mL^(-1) for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018–0.17 pg g^(-1) to 0.13–0.36 pg g^(-1), respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation.Huizhong Sun Pu Wang Honghua Li Yingming Li Shucheng Zheng Julius Matsiko Yanfen Hao Weiwei Zhang Dou Wang Qinghua Zhang 2017Science China Chemistry2017,60,5:6
9Research on Mechanisms of Steam Breakthrough and Profile Control Design for Steam Soaking Well显示文摘Scaled physical model tests for steam breakthrough were conducted based on the analysis of mechanisms and influence factors of steam breakthrough. Physical simulation results showed that at the initial steam breakthrough, preferential flow channels were formed in narrow sand packs and most residual oil left in these channels was immobile. This shortened the steam breakthrough time of follow-up steam flooding and decreased the increment of oil recovery efficiency. Steam breakthrough occurred easily for a smaller producer-injector spacing, and a bigger difference in physical properties between fluids and rock. Steam breakthrough is more likely to occur at a larger formation permeability (k), greater steam displacement velocity (u) and smaller producer-injector spacing (L). Steam breakthrough time is a function of the parameter group (uk/L), i.e. tb=3.2151 (uk/L) -0.5142. A non piston-like displacement model was built based on steam breakthrough observation for a steam stimulated well in the Jinglou Oilfield, Henan Oilfield Company. The steam volume swept in different directions could be obtained from inter-well permeability capacity and breakthrough angle, and the steam swept pore volume (SSPV) was also determined. Numerical simulation showed that steam sweep efficiency reached its peak value when a slug of profile control agent (slug size 10%-15% SSPV) was set at one half of the inter-well spacing. Field test with 12.5% SSPV of profile control agents in the Jinglou Oilfield achieved success in sealing breakthrough channels and good production performance of adjacent producers.Liu Huiqing Zhang Hongling Wang Shulin Wang Han Bao Shucheng 2006Petroleum Science2006,3,3:5
10Discovering unusual structures from exception using big data and machine learning techniques显示文摘Recently, machine learning(ML) has become a widely used technique in materials science study. Most work focuses on predicting the rule and overall trend by building a machine learning model. However,new insights are often learnt from exceptions against the overall trend. In this work, we demonstrate that how unusual structures are discovered from exceptions when machine learning is used to get the relationship between atomic and electronic structures based on big data from high-throughput calculation database. For example, after training an ML model for the relationship between atomic and electronic structures of crystals, we find AgO2 F, an unusual structure with both Ag3+and O22à, from structures whose band gap deviates much from the prediction made by our model. A further investigation on this structure might shed light into the research on anionic redox in transition metal oxides of Li-ion batteries.Jianshu Jie Zongxiang Hu Guoyu Qian Mouyi Weng Shunning Li Shucheng Li Mingyu Hu Dong Chen Weiji Xiao Jiaxin Zheng Lin-Wang Wang Feng Pan 2019Science Bulletin2019,64,9:5
11A new MaterialGo database and its comparison with other high-throughput electronic structure databases for their predicted energy band gaps显示文摘Recently, many high-throughput calculation materials databases have been constructed and found wide applications. However, a database is only useful if its content is reliable and sufficiently accurate. It is thus of paramount importance to gauge the reliabilities and accuracies of these databases. Although many properties have been predicted accurately in these databases,electronic band gap is well known to be underestimated by traditional density functional theory(DFT) calculations under local density approximation(LDA), which becomes a challenging problem for materials database building. Here, we introduce MaterialGo(http://gffzz077c307637e74fb9honb656cvpvu66fqp.ffgz.tsg.suse.edu.cn/data-base.html), a new database calculating the band structures of crystals using both Perdew-Burke-Ernzerhof(PBE) exchange-correlation functional and Heyd-Scuseria-Ernzerhof(HSE) hybrid functional.Comparing different PBE databases, it is found that their band gaps are consistent when no U parameter is used for transition metal d-state or heavy element f-state to correct their self-interaction error, but rather different when PBE+U are used, mostly because of the different values of U used in different database. HSE calculations under standard parameters will give larger band gaps that are closer to experiment. Based on the high-throughput HSE calculations over 10000 crystal structures, we might have a better understanding of the relationship between crystal structures and electronic structures, which will help us to further explore material genome science and engineering.JIE JianShu WENG MouYi LI ShunNing CHEN Dong LI ShuCheng XIAO WeiJi ZHENG JiaXin PAN Feng Wang LinWang 2019Science China(Technological Sciences)2019,62,8:4
12Mechanisms of carbon storage and the coupled carbon, nitrogen and sulfur cycles in regional seas in response to global change显示文摘1.Great challenges in scientific frontiers of marine carbon storage in the scenario of global change The marine carbon cycle is influenced by anthropogenic activities,affecting global climate change and casting a significant impact on ecosystems.However,the complex spatiotemporal process of the marine carbon cycle results in the uncertainty in the estimation of marine carbon budget。XIE ShuCheng CHEN JianFang WANG FengPing XUN LuYing TANG Kai ZHAI WeiDong LIU JiHua MA WenTao 2017Science China Earth Sciences2017,60,5:3
13Atmospheric levels and distribution of Dechlorane Plus in an E-waste dismantling region of East China显示文摘Atmospheric concentrations of Dechlorane Plus(DP)were investigated in Taizhou,an electronic-waste(E-waste)dismantling region in East China.Passive air samplers with polyurethane foam(PUF)disks were deployed every three months during the sampling period of September 2009-August 2010.The total DP(syn-and anti-DP)concentrations in air ranged from not detected to 277 pg/m^3,with a mean concentration of 53.9 pg/m^3.A generally declining trend of DP levels was found from the E-waste dismantling region to the peripheral areas.The median values of total DP concentrations in autumn,winter,spring and summer were 52.2,28.8,39.7 and 30.1 pg/m^3,respectively.The seasonal variations of DP concentrations were mainly associated with the intensity of E-waste dismantling activities and meteorological conditions.The mean value of anti-DP fractional abundance(f_(anti))was 0.74±0.08,which was consistent with those in the commercial DP products.This study confirmed a significant emission source related to the distribution of atmospheric DP in the E-waste dismantling area and supplied information for the seasonal variation of DP in the atmosphere.Huizhong Sun Yingming Li Pu Wang Shucheng Zheng Julius Matsiko Dou Wang Weiwei Zhang Yanfen Hao Qinghua Zhang Guibin Jiang 2017Science China Chemistry2017,60,2:2
14Optimization of acid digestion conditions on the extraction of fatty acids from stalagmites显示文摘在石笋的类脂化合物为古气候重建被看了潜力。然而,因为样品的大质量被要求,低类脂化合物内容在在石笋获得高决定类脂化合物记录导致困难。以前的研究验证了酸消化能改进类脂化合物,特别丰满的酸(船边交货) 和 3-hydroxy 的收益丰满的酸(3-OH-FAs ) 。为了与有限石笋获得船边交货和 3-OH-FAs 的更多的内容,取样重量,我们这里调查酸消化怎么调节(HCl 集中,加热温度和时间持续时间) 能影响船边交货和 3-OH-FAs 的收益。在 HCl 的不同集中下面,从 2.0 ~ 6.0 mol/L,船边交货把一样的步放在内容有 3-OHFAs 的变化,和二的最高的收益出现在 3 mol/L HCl 下面。3-OH-FAs 的内容从 80 与加热温度断然增加 ? 慩瑮潵 ?Canfa WANG Hongbin ZHANG Xianyu HUANG Junhua HUANG Shucheng XIE 2012Frontiers of Earth Science2012,6,1:2
15Stable perovskite solar cells with efficiency of 22.6%via quinoxaline-based polymeric hole transport material显示文摘Poor stability of spiro-OMe TAD hole transport materials(HTMs)with dopant is a major obstacle for the commercialization of perovskite solar cells(pero-SCs).Herein,we demonstrate a series of quinoxaline-based D-A copolymers PBQ5,PBQ6 and PBQ10 as the dopant-free polymer HTMs for high performance pero-SCs.The D-A copolymers are composed of fluorothienyl benzodithiophene(BDTT)as D-unit,difluoroquinoxaline(DFQ)with different side chains as A-unit,and thiophene asπ-bridge,where the side chains on the DFQ unit are bi-alkyl for PBQ5,bi-alkyl-fluorothienyl for PBQ6,and alkoxyl for PBQ10.All the three copolymers are adopted as the dopant-free HTM in the pero-SCs.The planar n-i-p structured pero-SCs based on(FAPb I_(3))_(0.98)(MAPb Br_(3))_(0.02)with PBQ6 HTM demonstrated the high power conversion efficiency(PCE)of 22.6%with Vocof1.13 V and FF of 80.8%,which is benefitted from the suitable energy level and high hole mobility of PBQ6.The PCE of 22.6%is the highest efficiency reported in the n-i-p structured pero-SCs based on dopant-free D-A copolymer HTM.In addition,the peroSCs show significantly enhanced ambient,thermal and light-soaking stability compared with the devices with traditional spiroOMe TAD HTM.Chenxing Lu Can Zhu Lei Meng Chenkai Sun Wenbin Lai Shucheng Qin Jinyuan Zhang Wenchao Huang Jiaqi Du Yiyang Wang Yongfang Li 2021Science China Chemistry2021,64,11:2
16Dependable and secure sensor data storage with dynamic integrity assurance 显示文摘Wang Qian Ren Kui Yu Shucheng 2011ACM Transon Sensor Networks2011,8,1:1
17An Attenuated Highly Pathogenic Chinese PRRS Viral Vaccine Confers Cross Protection to Pigs against Challenge with the Emerging PRRSV NADC30-Like Strain显示文摘A novel PRRSV strain was isolated in China that was genetically similar to the NADC30 strain which is reported to have spread throughout China. The objective of the present study was to evaluate the cross-protective efficacy of the live vaccine TJM-F92 in young pigs against challenge with a NADC30-like strain, HN201605. Twenty-five PRRSV-and antibody-free pigs were randomly divided into the following five groups: Vac/ChA, Unvac/ChA, Vac/ChB, Unvac/ChB and the mock.The pigs in groups Vac/ChA and Vac/ChB were inoculated intramuscularly with 1 mL TJM-F92(10^(5.0) TCID_(50)/mL). At28 days post vaccination(0 days post challenge), groups Vac/ChA and Unvac/ChA were inoculated intranasally with 10^(4.5) TCID_(50)/mL PRRSV strain TJ F3(2 mL/pig), while groups Vac/ChB and Unvac/Ch B were inoculated, using the same route, with the same dose of the NADC30-like strain HN201605 F3. Protective effects of the PRRSV strain were observed in all pigs in the Vac/ChA and Vac/ChB groups. Neither high fever nor signs of clinical disease were observed through the experiment in these groups, whereas pigs in Unvac/ChA group exhibited serious clinical symptoms, pathological lesions,and weight loss. In Unvac/ChB group, pigs developed milder clinical symptoms, which demonstrated that the NADC30-like strain HN201605 had moderate pathogenicity. The results suggest that the MLV vaccine strain TJM-F92 is an effective and safe vaccine candidate for use in China.Hewei Zhang Mingqi Xia Wei Wang Decai Ju Long Cao Bai Wu Xin Wang Ying Wu Ni Song Jiaxin Hu Changxiao Tian Shucheng Zhang Hua Wu 2018Virologica Sinica2018,33,2:1
18Effects of reverse voltage and subzero startup on the membrane electrode assembly of a PEMFC显示文摘Hongwei Wang Junbo Hou Hongmei Yu Shucheng Sun 2007Journal of Power Sources2007,,1:1
19An Analysis of china's Economic Growth Trend (1998-2002)显示文摘 Wang Lina Chang Xin 2006china & world Economy2006,,4:1
20Synchronous nanoscale topographic and chemical mapping by differential-confocal controlled Raman microscopy显示文摘Confocal Raman microscopy is currently used for label-free optical sensing and imaging within the biological,engineering,and physical sciences as well as in industry.However,currently these methods have limitations,including their low spatial resolution and poor focus stability,that restrict the breadth of new applications.This paper now introduces differential-confocal controlled Raman microscopy as a technique that fuses differential confocal microscopy and Raman spectroscopy,enabling the point-to-point collection of three-dimensional nanoscale topographic information with the simultaneous reconstruction of corresponding chemical information.The microscope collects the scattered Raman light together with the Rayleigh light,both as Rayleigh scattered and reflected light(these are normally filtered out in conventional confocal Raman systems).Inherent in the design of the instrument is a significant improvement in the axial focusing resolution of topographical features in the image(to^1 nm),which,when coupled with super-resolution image restoration,gives a lateral resolution of 220 nm.By using differential confocal imaging for controlling the Raman imaging,the system presents a significant enhancement of the focusing and measurement accuracy,precision,and stability(with an antidrift capability),mitigating against both thermal and vibrational artefacts.We also demonstrate an improved scan speed,arising as a consequence of the nonaxial scanning mode.HAN CUI YUN WANG LIRONG QIU SHUCHENG LI JONATHAN M.COOPER AND WEIQIAN ZHAO 2020Photonics Research2020,8,9:1
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