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| 1 | Effect of triethylamine treatment of titanium silicalite-1 on propylene epoxidation显示文摘与 triethylamine (茶)对待的钛 silicalite-1 ( TS-1 )在不同条件下面的答案被X光检查粉末衍射( XRD )描绘,Fourier变换红外线的光谱( FTIR ),紫外可见的弥漫的反射光谱(紫外力),氮物理吸附和解吸附作用,扫描电子显微镜学( SEM )和传播电子显微镜学( TEM )。描述结果显示出那许多不规则凹陷与增加茶集中,和处理温度和时间由于框架硅和空洞增加的体积的随机的溶解在 TS-1 晶体被产生。修改 TS-1 样品由于 hollows 的产生可能在一个改正床反应堆为丙烯的 epoxidation 在改变度改进了催化剂生活使让反应物和产品从隧道扩散容易。 | Juan XU Yaquan WANG Wenping FENG Yi LIN Shuhai WANG | 2014 | Frontiers of Chemical Science and Engineering2014，8，4： | 13 |
| 2 | Inhibition of lung cancer cell proliferation mediated by human mesenchymal stem cells显示文摘人的间充质的干细胞(hMSCs ) 主要为他们的潜在的临床的使用被学习。最近,癌症研究的领域里的许多注意对 hMSCs 被给予了。在这研究,我们由使用一个合作文化系统和调节 hMSCs 的媒介在 vitro 并且在 vivo 在肺癌症房间线 SK-MES-1 和 A549 的增长上调查了 hMSCs 的影响。我们的结果证明 hMSCs 能禁止 SK-MES-1 和 A549 房间的增长,并且经由一些可溶的因素在 vitro 导致肿瘤房间的 apoptosis。动物学习证明从 hMSCs 的这些可溶的因素能由 preliminarily 与调节 hMSCs 的媒介对待肿瘤细胞压制 tumorigenesis 和肿瘤 angiogenesis。在肿瘤房间的脉管的 endothelial 生长因素的 downregulated 表示可能是在肿瘤 angiogenesis 的干扰的机制,它被西方的污点分析和 immunohistochemistry 试金验证。一起拿,我们的结果建议 hMSCs 能由 secreting 一些禁止肿瘤细胞生长可溶的因素。 | Lin Li Hui Tian Zhitao Chen Weiming Yue Shuhai Li Wenjun Li | 2011 | Acta Biochimica et Biophysica Sinica2011，43，2： | 11 |
| 3 | Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo显示文摘肺癌症是在整个世界的癌症相关的死亡的领先的原因。在最近的年里,肺的腺癌在频率超过了有鳞的房间癌并且是在许多国家的肺癌症的占优势的形式。流行病学的调查显示出在消费和死亡从许多癌症评估的大蒜(瞀或蒜之类 sativum ) 之间的一种反的关系。Diallyl trisulfide (DATS ) 是导出大蒜的混合物之一(是也知道:organosulfer 混合物,振荡) 。DATS 能导致 apoptosis 并且禁止许多癌症细胞线的生长。我们的学习证明 DATS 导致的 apoptotic 事件是通过导致了 Bax/Bcl-2 和 caspase-3, -8, 和 -9 的活动的比率的起来规定的 anti-apoptotic Bcl-2 的重要减少的线粒体依赖者 caspase 串联。最后, DATS 导致了 apoptosis 并且在一个集中依赖者和时间依赖者举止禁止了增长。由与 A549 异种皮移植建立女 BALB/c 裸体老鼠的一个动物模特儿,没有与控制组相比引起重量损失或任何另外的副作用,而且,我们在裸体老鼠发现 DATS 的那口头的 gavage A549 异种皮移植的显著地延迟的生长。在 vitro 并且在 vivo 的所有证据建议 DATS 能是理想的反癌症药。 | Wenjun Li Hui Tian Lin Li Shuhai Li Weiming Yue Zhitao Chen Lei Qi Wensi Hu Yingchao Zhu Bin Hao Cun Gao Libo Si Fei Gao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 4 | Human mesenchymal stem cells with adenovirus-mediated TRAIL gene transduction have antitumor effects on esophageal cancer cell line Eca-109显示文摘apoptotic ligand TNF 相关的导致 apoptosis ligand (小道) 被相信是癌症 genetherapy 的一个有希望的候选人,然而,全身地处理这疾病的基因治疗策略被 thevector 的低效的交货经常损害到肿瘤组织。间充质的干细胞(MSC ) 被显示出到家到肿瘤地点并且能潜在地 actas 为 antitumor 基因治疗向量的盾和车辆。这里,我们使用了表示小道到 transduceMSCs 的 adenoviral 向量并且在食道的癌症房间 Eca-109 上学习了这些带小道的 MSC 的导致 apoptosis 活动。我们在 vitro,表示小道的 MSC 能禁止增长并且由 MTT 试金, co-cultureexperiments 和流动 cytometry 分析在 Eca-109 房间导致 apoptosis 的 resultsshowed。在 vivo,表示小道的 MSC 也显示了一个能力在一个 Eca-109 异种皮移植老鼠模型禁止肿瘤生长。一起, ourfindings 显示基于 MSCs 的小道基因交货的基因治疗策略为食道的癌症的 improvingthe 治疗有宽潜在的价值。 | Lin Li Fengling Li Hui Tian Weiming Yue Shuhai Li Guanqing Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，6： | 5 |
| 5 | Down-regulation of heparanase leads to the inhibition of invasion and proliferation of A549 cells in vitro and in vivo显示文摘Heparanase 是降级的哺乳动物的 endoglycosidase 在房间表面并且在细胞外的矩阵的 heparan 硫酸盐。heparanase 的表示在许多人的恶意的肿瘤被检测并且仔细把侵略,转移,和 angiogenesis 与肿瘤联系了。然而, heparanase 的特定的角色和它调整非小的房间肺癌症(NSCLC ) 的恶意的潜力的机制房间仍然保持不清楚。在现在的学习, heparanase 的表示在由 antisense oligodeoxynucleotide 的 NSCLC 房间线是下面调整的。结果证明 heparanase 的下面规定导致了重要抑制侵略并且在 vitro 并且在 vivo 的 A549 房间的 proliferative 潜力。进一步的研究证明 heparanase 的下面规定显著地禁止了 A549 房间的 angiogenic 潜力,它可能是为在在 vivo 的 BALB/c 裸体老鼠的 A549 房间增长的抑制负责的机制。这些调查结果证明 heparanase 在调整 A549 房间的侵略,增长,和 angiogenesis 起必要作用。 | Zhitao Chen Liangming Zhu Xiaohua Li Hui Tian Yusong Fang Haibo Liu Shuhai Li Lin Li Weiming Yue Wenjun Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 3 |
| 6 | siRNA of DNA polymerase iota inhibits the migration and invasion in the lung cancer cell A549显示文摘 | Lin Li Hui Tian Chuanle Cheng Shuhai Li Lu Ming Lei Qi | 2018 | Acta Biochimica et Biophysica Sinica2018，50，9： | 2 |
| 7 | Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line显示文摘联系转移的蛋白质 1 (MTA1 ) 高表示在许多人的好攻击的肿瘤被检测了并且在象侵略,转移,和 angiogenesis 那样的恶意的生物行为起重要作用。然而,在调整 non-small-cell 肺癌症(NSCLC ) 的恶意的行为的 MTA1 蛋白质的特定的角色和机制房间仍然保持不清楚。阐明 MTA1 蛋白质的详细函数,我们下面调整在由在 vitro 的 RNA 干扰(RNAi ) 的 NSCLC 房间线的 MTA1 蛋白质表达式,并且发现 MTA1 蛋白质的下面规定显著地禁止了 95D 房间的移植和侵略潜力。进一步的研究表明 MTA1 蛋白质的下面规定显著地减少了矩阵 metalloproteinase-9 的活动,它能是为 95D 房间移植和侵略的抑制负责的机制。另外,试管形成试金证明 MTA1-siRNA 95D 房间的调节媒介导致的完全的试管的数字比 95D 房间的显著地小。这些调查结果证明那 MTA1 蛋白质在调整 95D 房间的迁居,侵略,和 angiogenesis 潜力起重要作用,由 RNAi 建议那条 MTA1 蛋白质下面规定可能是一条新奇治疗学的途径禁止 NSCLC 的前进。 | Shuhai Li Hui Tian Weiming Yue Lin Li Cun Gao Libo Si Wenjun Li Wensi Hu Lei Qi Ming Lu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，2： | 2 |
| 8 | Metabolite profiling of plasma and urine from rats with TNBS‐induced acute colitis using UPLC‐ESI‐QTOF‐MS‐based metabonomics – a pilot study显示文摘 | Xiaojun Zhang Franky F. K. Choi Yan Zhou Feung P. Leung Shun Tan Shuhai Lin Hongxi Xu Wei Jia Joseph J. Y. Sung Zongwei Cai Zhaoxiang Bian | 2012 | FEBS Journal2012，，： | 2 |
| 9 | Effect of NaOH Treatment on Catalytic Performance of ZSM -5 in Cyclohexene Hydration显示文摘ZSM-5 zeolite prepared by a hydrothermal method with the addition of seeds was treated with different concentrations of NaOH.The obtained samples were characterized by XRD,N_2 adsorption,NH_3-TPD,FT-IR,SEM,and studied in the catalytic performance of the hydration of cyclohexene to cyclohexanol.The characterization results showed that with the increase of NaOH concentration,the crystallinity of the treated samples decreased monotonously,and the acid sites of ZSM-5 zeolites first increased and then decreased,while more mesopores formed inside the ZSM-5zeolites.The experimental results of catalytic performance showed that cyclohexene conversion can be improved through introducing the mesopores and enhancing the acidity of ZSM-5 with the NaOH treatment at a low concentration.The highest cyclohexene conversion of 12.8%was obtained when the concentrations of NaOH solution were in the range of 0.2-0.6 mol/L.The selectivity of cyclohexanol on all samples was higher than 99.6%. | Yaquan Wang Shougui Wang Fanjun Meng Shuhai Wang Jiaxin Ye Yongjie Lin | 2017 | Transactions of Tianjin University2017，23，1： | 1 |
| 10 | Deactivation and regeneration of TS-1/SiO2 catalyst for epoxidation of propylene with hydrogen peroxide in a fixed-bed reactor显示文摘为有在一个改正床反应堆的氢过氧化物的丙烯的 epoxidation 的 TS-1/SiO2 催化剂被调查了。逐渐地,与丙烯的联机反应时间,而是选择, epoxide 在大约 93% 点被保留的催化剂活动减少。新鲜、撤销并且再生的催化剂与 X 光检查衍射被描绘, Fourier 变换红外线的光谱学, ultra-violet-visible 弥漫的反射, Brunner-Emmett-Teller 方法和 thermogravimetric 分析,和撤销催化剂与 H2O2/methanol 被改革溶液。与新鲜催化剂相比,框架结构和在撤销并且再生的 TS-1/SiO2 催化剂的框架的钛的内容没被改变。催化剂释放的主要原因是由笨重器官的副产品的催化剂的隧道的阻塞,它在 TS-1 盖住钛的活跃中心。撤销 TS-1/SiO2 催化剂上的扔的材料能被处理与氢过氧化物 / 甲醇答案或纯甲醇移开;更高处理温度并且越高在甲醇的 H2O2 的集中,越 higher 新生的程度。新生处理没在丙烯 epoxidation 影响产品选择。 | Hainan SHI Yaquan WANG Guoqiang WU Wenping FENG Yi Lin Teng ZHANG Xing JIN Shuhai WANG Xiaoxue WU Pengxu YAO | 2013 | Frontiers of Chemical Science and Engineering2013，7，2： | 1 |
| 11 | Characterization of steroidal saponins in crude extract from Dioscorea nipponica Makino by liquid chromatography tandem multi-stage mass spectrometry 显示文摘 | LIN Shuhai WANG Dongmei YANG Depo | 2007 | Anal Chim Acta2007，599，： | 1 |
| 12 | Characterization of steroidal saponins in crude extract from Dioscorea nipponica Makino by liquid chromatography tandem multi-stage mass spectrometry显示文摘 | LIN Shuhai WANG Dongmei YANG Depo | 2007 | Analytica Chimica Acta2007，599，1： | 1 |
| 13 | Microstructure development, mechanical properties and formability of Mg–Zn–Y–Zr magnesium alloy显示文摘 | Qiang Chen Jun Lin Dayu Shu Chuankai Hu Zude Zhao Feng Kang Shuhai Huang Baoguo Yuan | 2012 | Materials Science & Engineering A2012，，： | 1 |
| 14 | Characterization of steroidal saponins in etude extract from dioseorea nipponiea Makino by liquid chromatography tandem multi stage mass spectrometry 显示文摘 | Shuhai Lin Dongmei Wang Depo Yang | 2007 | Analytiea Chimiea Aeta2007，7，7： | 1 |
| 15 | Early Diagenetic Dolomite as a Potential Archive of Paleoredox Fluctuations in an Early Tonian Marine Basin?显示文摘The Tonian Period witnessed important environmental changes and critical evolutionary innovations. Published iron speciation data suggest a global redox transition of mid-depth seawaters from euxinic to ferruginous in early Tonian, but details of this transition remain unknown. This study explores Tonian stromatolitic carbonates as a possible archive of paleoenvironmental changes, through the investigation of dolomitic limestones and dolostones associated with stromatolites of the Weiji Formation in the Huaibei region of North China. Three types of dolomitization are recognized on the basis of petrographic and geochemical data. Type Ⅰ and Ⅱ dolomitization resulted in dolomitic limestones characterized by LREE depletions, MREE enrichments, positive yttrium anomalies, and a lack of europium anomalies, indicating early diagenetic dolomitization, possibly in the iron reduction zone and under the influence of bottom seawater. The lack of cerium anomalies in these carbonates suggests anoxia in shallow marine environments. The coexistence of ferroan/non-ferroan dolomite crystals and overgrowth bands is interpreted as possible evidence for rapid fluctuations between iron-rich and iron-depleted conditions in pore-waters or seawaters. In contrast, type Ⅲdolomitization resulted in pervasively dolomitized stromatolitic carbonates and likely represents late diagenetic processes. This study highlights the potential of early diagenetic dolomite as an archive for paleoenvironmental investigations. | KANG Junyao LI Chenqing DONG Lin XIAO Shuhai | 2022 | Acta Geologica Sinica(English Edition)2022，96，2： | 0 |
| 16 | Precise Synthesis of Organic Heterostructures via the Synergy Approach of Polymorphism and Cocrystal Engineering for Optical Applications显示文摘Organic heterostructures that can integrate the physiochemical properties of two or more substances have atracted widespread attention in the field of optoelectronics.However,the epitaxial growth process between different organic material molecules is unpredictable,and the precise synthesis of organic heterostructures is stll particularly challenging.Herein,through the synergy approach of polymorphism and cocrystal engineering,a series of organic branched heterostructures have been successfully prepared.Interestingly,by simply adjusting the solvent ratio,different crystalline phases of perylene microplates can be epitaxilly grown on the perylene-OFN cocrystal microwires,which provides a feasible approach for the preparation of organic heterostructures.Meanwhile,these as-prepared organic branched heterostructures can realize multi-channel and multi-color emission,and act as optical logic gates,which promotes the multifunctional integrated optoelectronics. | Huiling Yin Yingxin Ma Hongtao Lin Shuhai Chen Ziyan Zhou Shuping Zhuo Xuedong Wang | 2022 | Chinese Journal of Chemistry2022，40，10： | 0 |
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