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18篇 您的检索式:作者名="Shuo Z"
    题名 作者 年代 出处 被引量
1^11C-PIBPET和^18F-FDGPET显像诊断阿尔茨海默病与遗忘型轻度认知损害的临床价值显示文摘目的应用11C-PIB PET和18F-FDG PET显像研究阿尔茨海默病和遗忘型轻度认知损害患者β-淀粉样蛋白(Aβ)沉积与葡萄糖代谢之间的关系,联合载脂蛋白E(ApoE)基因型进一步探讨遗忘型轻度认知损害与阿尔茨海默病的相关性。方法利用PET显像对阿尔茨海默病(14例)、遗忘型轻度认知损害(10例)和正常对照者(5例)脑组织Aβ沉积和葡萄糖代谢变化进行分析,采用聚合酶链反应-限制性片段长度多态性方法对ApoE基因型进行分析。结果阿尔茨海默病组患者11C-PIB标准化摄取比值在下顶叶、颞叶外侧、额叶、后扣带回皮质和楔前叶、枕叶和纹状体均高于正常对照组(P<0.05);遗忘型轻度认知损害组患者脑组织11C-PIB结合水平呈双峰形。11C-PIB+aMCI亚组与阿尔茨海默病组、11C-PIB-aMCI亚组与正常对照组之间11C-PIB标准化摄取比值差异均无统计学意义(P>0.05)。18F-FDG PET显像显示,3/5例11C-PIB+aMCI亚组患者双侧顶叶、颞叶和楔前叶代谢减低,其中2例ApoEε4等位基因携带者随访期间进展至阿尔茨海默病;3/5例11C-PIB-aMCI亚组患者双侧额叶和前扣带回代谢减低。结论11C-PIB PET显像是筛查具有阿尔茨海默病病理特点的遗忘型轻度认知损害患者的有效工具。具有阿尔茨海默病病理特征的遗忘型轻度认知损害患者可伴有顶叶、颞叶外侧皮质和楔前叶代谢减低,其中ApoEε4等位基因携带者更易进展至阿尔茨海默病痴呆。Shi Zhihong Wang Ying Liu Shuai Liu Shuling Z hou Yuying Wang Jinhuan Cai Li Gao Shuo Ji Yong 2014中国现代神经疾病杂志2014,14,3:8
2Combination of intraoperative embolisation with surgical resection for treatment of giant cerebral arteriovenous malformations显示文摘 Shuo W jingshen L 2000J Clin Neurosci2000,7,1:1
3Security vulnerabilities:From analysis to detection and masking techniques显示文摘Chen Shuo Xu Jun Kalbarzyk Z T 2006Procecdings of the IEEE2006,94,2:1
4Hemodynamic simulation of the effect of asymmetric entry velocity profile on wall shear stress in carotid bifurcation model显示文摘Zurong D Shuo Y Xiaoli Z 2006J Biomech2006,39,1:1
5Combination of intraoperative embolisation with surgical resection for treatment of giant cerebral arteriovenous malformations显示文摘Jizong Z Shuo W Jingshen L 2000J Clin Neurosci2000,7,1:1
6Androgen receptor expression in male breast cancer predicts inferior outcome and poor response to tamoxifen treatment 显示文摘Wenhui Z Shuo L Dabei T 2014Eur J Endocrinol2014,171,4:1
7SAR Image Target Detection in Complex Environments Based on Improved Visual Attention Algorithm显示文摘Shuo L Caoe Z 2014EurasipJournal on Wireless Communications and Networking2014,2014,1:1
8Separation of majorcatechins from green tea by ultrahigh pressure extraction显示文摘JUN X SHUO Z BINGBING L 2010Int JPharm2010,386,12:1
9A polysaccharide, MDG- 1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart 显示文摘Shuo W Zhang Z Xiao L 2010Glycobiology2010,20,4:1
10Acute toxicity, biochemical and gene expression responses of the earthworm Eisenia fetida exposed to polycyclic musks显示文摘Chun C Qixing Z Shuo L 2011Chemosphere2011,83,8:1
11androgen receptor expression in male breast cancer predicts inferior outcome and poor response to tamoxifen treatmen 显示文摘WENHUI Z SHUO L DABEI T 2014Eur En- doerinol2014,171,4:1
12Security vulnerabilities: From analysis to detection and masking techniques显示文摘CHEN SHUO XU JUN KALBARCZYK Z T 2006Proceedings of the IEEE2006,94,2:1
13Attenuation of ischemia-induced rat brain injury by 2-(-2-benzofuranyl)-2-imidazoline,a high selectivity ligand for imidazoline I2 receptors显示文摘Han Z Xiao MJ Shuo B 2009Neurol Res2009,31,4:1
14Enzyme-linked immunosorbent assay and colloidal gold immunoassay for sulphamethazine residues in edible animal foods:investigation of the effects of the analytical conditions and the sample matrix on assay performance显示文摘Wang L Wang S Shuo Z 2008ANALYTICAL AND BIOANALYTICAL CHEMISTRY2008,390,6:1
15The use of a tea polyphenol dip to extend the shelf life of Silver carp(ItypophthMmwthys rnolhdx)during storage in ice显示文摘Wenjiao F Yuanlong C Shuo Z 2008Food Chemistry2008,108,:1
16Preparation and characterization of BiV O4 film electrode and investigation of its photoelectrocatalytic ability under visible light显示文摘Xiu F Z Shuo C Xie Q 2009Separation and Purification Technology2009,64,3:1
17Fabrication of photocatalytic membrane and evaluation its efficiency in removal of organic pollutants from water 显示文摘HAIMIN Z XIE Q SHUO C 2006Separation and Purification Technology2006,50,:1
18Scan power-aware deterministictest scheme using a low-transition linear decompressor显示文摘Wang W Z Shuo C Xiang L Y 2015International Journal of Electronics2015,102,4:1
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