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| 1 | Xa7, a new executor R gene that confers durable and broad-spectrum resistance to bacterial blight disease in rice显示文摘Bacterial blight(BB)is a globally devastating rice disease caused by Xanthomonas oryzae pv.oryzae(Xoo).The use of disease resistance(R)genes in rice breeding is an effective and economical strategy for the control of this disease.Nevertheless,a majority of R genes lack durable resistance for long-term use under global warming conditions.Here,we report the isolation of a novel executor R gene,Xa7,that confers extremely durable,broad-spectrum,and heat-tolerant resistance to Xoo.The expression of Xa7 was induced by incompatible Xoo strains that secreted the transcription activator-like effector(TALE)AvrXa7 or PthXo3,which recognized effector binding elements(EBEs)in the Xa7 promoter.Furthermore,Xa7 induction was faster and stronger under high temperatures.Overexpression of Xa7 or co-transformation of Xa7 with avrXa7 triggered a hypersensitive response in plants.Constitutive expression of Xa7 activated a defense response in the absence of Xoo but inhibited the growth of transgenic rice plants.In addition,analysis of over 3000 rice varieties showed that the Xa7 locuswas found primarily in the indica and aus subgroups.A variation consisting of an 11-bp insertion and a base substitution(G to T)was found in EBEAvrXa7 in the tested varieties,resulting in a loss of Xa7 BB resistance.Through a decade of effort,we have identified an important BB resistance gene and characterized its distinctive interaction with Xoo strains;these findings will greatly facilitate research on the molecular mechanism of Xa7-mediated resistance and promote the use of this valuable gene in breeding. | Xifeng Chen Pengcheng Liu Le Mei Xiaoling He Long Chen Hui Liu Shurong Shen Zhandong Ji Xixi Zheng Yuchen Zhang Zhenyu Gao Dali Zeng Qian Qian Bojun Ma | 2021 | Plant Communications2021，2，3： | 9 |
| 2 | Activity after Site-Directed Mutagenesis of CD59 on Complement-Mediated Cytolysis显示文摘CD59 may inhibit the cytolytic activity of complement by binding to C8/C9 and protect host cell membranes against homologous membrane attack complex (MAC). However,CD59 is widely overexpressed on tumor cells,which has been implicated in tumorigenesis. The active site of CD59 relative to MAC is still confused. As reported the MAC binding site is located in the vicinity of a hydrophobic groove on the membrane distal face of the protein centered around residue W40. Here two site-directed mutagenesis were performed by overlapping extension PCR to delete residue W40 site (Mutant 1,M1) or to change C39W40K41 to W39W40W41 (Mutant 2,M2). Then we constructed mutant CD59 eukaryotic expression system and investigated their biological function on CHO cells compared with wild-type CD59. Stable populations of CHO cells expressing recombinant proteins were screened by immunotechnique. After 30 passages culturing,proteins could be tested. Dye release assays suggest that M1CD59 loses the activity against complement,while M2CD59 increases the anti-complement activity slightly. Results indicate that W40 of human CD59 is important to its activity,and prohibition of this site may be a potential way to increase complement activity and to treat tumors. | Xinhong Zhu Meihua Gao Shurong Ren Qiubo Wang Cunzhi Lin | 2008 | Cellular & Molecular Immunology2008，5，2： | 8 |
| 3 | Preparation and Characterization of High Infrared Emissivity Mn-doped NCO Spinel Composites显示文摘NiCr_2O_4(NCO)spinel composites with different Mn/Ni atomic ratios(Mn/Ni=0.05,0.10,0.15,and 0.20)were synthesized via solid state reaction method.Phase compositions and microstructure of samples were characterized by X-ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS).The TG-DSC curves showed that the appropriate baking temperature for Mn-doped NCO spinel preparation was approximately 1 320℃.X-ray diffraction patterns exhibited the formation of NCO spinel with Fd-3m space group.Valence state of the Mn ions was determined from 2p and 3s X-ray photoelectron spectra.Manganese ions were mostly in divalent and trivalent states,and the ratio of Mn^(2+)/Mn^(3+)was 0.78-0.98.Fourier transform infrared spectroscopy(FTIR)was used to analyze the spectral emissivity of Mn doped NCO spinel.It was revealed that the infrared emissivity of Mn-doped NCO spinel in 1.8-5μm could be significantly enhanced with increasing content of Mn^(2+),reaching as high as 0.9398.Mn-doped NCO spinel showed excellent radiation performance and good prospect in high emissivity applications in the temperature range of 800-1 200℃. | 邹隽 DONG Shurong GAO Junhua WANG Hongfu 程旭东 | 2017 | Journal of Wuhan University of Technology(Materials Science)2017，32，6： | 3 |
| 4 | Extractive denitrogenation of shale oil using imidazolium ionic liquids显示文摘The potential applications of shale oil as a substitute energy source are adversely influenced due to its high nitrogen content.In this work,four imidazolium ionic liquids(ILs),i.e.,1-butyl-3-methylimidazolium chloride([Bmim]Cl),1-butyl-3-methylimidazolium acetate([Bmim]Ac),1-butyl-3-methylimidazolium acetate/ZnAc2([Bmim]Ac/ZnAc2)and 1-butyl-3-methylimidazolium chloride/ZnAc2([Bmim]Cl/ZnAc2),were used to extract the basic nitrides and neutral nitrides from shale oil.The influence of extraction time,temperature,properties of N-compounds,ILs structure,mass ratio of IL/oil,multiple cycles of denitrogenation,physical mixing of ILs and ILs recyclability on extractive denitrogenation was systematically investigated.The denitrogenation performance of all ILs was determined and investigated from micro-level view withσ-profile.It was observed that,ILs composed of anions with weaker HB acceptor capacity,have the higher N-extraction efficiency to the neutral nitrogen compounds with weaker HB acceptor capacity.More than 96%N-extraction efficiency was achieved at the end of a single extraction cycle for time<10 min under 40℃C and 1:1 of IL:oil(w/w),especially 100%N-extraction efficiency was realized for carbazole and indole.The N-extraction efficiency up to 60.1%and 53.7%for real shale oil was realized by[Bmim]Ac and[Bmim]Ac/ZnAc2,respectively,which are about 10%better than other non-hydrodenitrogenation technologies.Moreover,[Bmim]Ac and[Bmim]Ac/ZnAc2 exhibited almost the same extractive denitrogenation performance after regeneration.This work has developed a new approach to lessen the nitrogen content of shale oil effectively and economically. | Shurong Gao Shengfan Fang Ruozheng Song Xiaochun Chen Guangren Yu | 2020 | Green Energy & Environment2020，5，2： | 3 |
| 5 | Research on Dinoasur Footprints in Zizhou, Shaanxi Province, China显示文摘In recent years,the discoveries of dinosaur footprints have been successively reported from Dianshi Town,Zizhou City,Shaanxi Province.The footprints include the tracks of theropod,ornithopod and sauropod as well.Actually,the dinosaur footprints were found by local inhabitants much earlier in history,but not for science.The slabs bearing the dinosaur footprints were collected for domestic use,such as building stones,millstones,cellar covers,sheepfold fences,windlass holders,etc.This paper is to describe the dinosaur footprints on both sides of three slabs used for cellar covers,sheepfold fences and windlass holders by the local people.24 dinosaur footprints and 4 trackways have been recognized and all of them belong to theropod.Four kinds of dinosaur footprints are identified,including 1 new ichnogenus and 2 new ichnospecies:(1)Shanbeipus caudatus ichnogen.et ichnosp.nov.;(2)Pengxianpus yulinensis ichnosp.nov.;(3)Eubrontes ichnosp;(4)Kayentapus ichnosp.Dinosaur-footprint-bearing beds were initially identified as the Fuxian Formation of the Lower Jurassic.Multipal dinosaur footprints associated with fragment plant fossils suggest a humid fluviolacustrine environment setting in the Ordos Basin during the early period of the Jurassic. | WANG Baopeng LI Jianjun BAI Zhiqiang GAO Junmin DONG Shurong HU Bailin ZHAO Suiqin CHANG Jieqiong | 2016 | Acta Geologica Sinica(English Edition)2016，90，1： | 2 |
| 6 | Effect of SC-CO 2 pretreatment in increasing rice straw biomass conversion显示文摘 | Miao Gao Feng Xu Shurong Li Xiaoci Ji Sanfeng Chen Dequan Zhang | 2010 | Biosystems Engineering2010，，4： | 1 |
| 7 | Nonisothermal Cocuring Behavior and Kinetics of Epoxy Resin/3-Glycidy- loxypropyl-POSS with MeTHPA显示文摘 | Gao Jungang Kong Dejuan Li Shurong | 2010 | Polymer Composites2010，31，1： | 1 |
| 8 | Nonisother-mal cocuring behavior and kinetics of epoxy resin-glycidyloxypropyl-POSS with MeTHPA显示文摘 | Jungang Gao Dejuan Kong Shurong Li | 2010 | PolymerComposites2010，31，1： | 1 |
| 9 | Logic-gated tumor-microenvironment nanoamplifier enables targeted delivery of CRISPR/Cas9 for multimodal cancer therapy显示文摘Recent innovations in nanomaterials inspire abundant novel tumor-targeting CRISPR-based gene therapies.However,the therapeutic efficiency of traditional targeted nanotherapeutic strategies is limited by that the biomarkers vary in a spatiotemporal-dependent manner with tumor progression.Here,we propose a self-amplifying logic-gated gene editing strategy for gene/H_(2)O_(2)-mediated/starvation multimodal cancer therapy.In this approach,a hypoxia-degradable covalent-organic framework(COF) is synthesized to coat a-ZIF-8 in which glucose oxidase(GOx) and CRISPR system are packaged.To intensify intracellular redox dyshomeostasis,DNAzymes which can cleave catalase mRNA are loaded as well.When the nano system gets into the tumor,the weakly acidic and hypoxic microenvironment degrades the ZIF-8@COF to activate GOx,which amplifies intracellular H^(+)and hypoxia,accelerating the nanocarrier degradation to guarantee available CRISPR plasmid and GOx release in target cells.These tandem reactions deplete glucose and oxygen,leading to logic-gated-triggered gene editing as well as synergistic gene/H_(2)O_(2)-mediated/starvation therapy.Overall,this approach highlights the biocomputing-based CRISPR delivery and underscores the great potential of precise cancer therapy. | Yongchun Pan Xiaowei Luan Fei Zeng Xuyuan Wang Shurong Qin Qianglan Lu Guanzhong He Yanfeng Gao Xiaolian Sun Xin Han Bangshun He Yujun Song | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 10 | Structural-functional unit ordering for high-performance electron-correlated materials显示文摘Electron-correlated materials have been drawing ever-increasing attention due to their fascinating physical behaviors and extensive application scenarios.In this review,a new method for material research and design(R&D),named structural-functional unit ordering(SFU ordering),which is presented,overcomes the shortcomings—for example,the limitation of finite chemical elements and long R&D circle-of conventional strategy and thus provides guidance for the design of these high-performance functional materials on demand.Meanwhile,with the development of material characterization technologies,SFUs of different scales and types can be directly observed,which,moreover,regulate the corresponding orderings.The review,starts with an introduction of the profile for SFU ordering and the synergistic effect between SFUs.Then,studies on several new high-performance electronic-correlated materials,for example,a ferromagnetic semiconductor with local spin,ferromagnetic metals with spin topologies,ferroelectric thin films with polar topologies,piezoelectric thin films with nanopillars enclosed by charged boundaries,thermoelectric materials with local ferromagnetic nanoparticles and topotactic phase transformation with conducting nanofilaments are stated in detail one by one.The vital aspect is the breaking of local symmetry,the construction,the structure,of SFUs and their orderings existing or theoretically existing,together with the enhanced/new performance.All in all,the main comments of the review tend to the remaining challenges,promising design approaches for the SFUs,and their orderings for high-performance functional materials. | Guyang Peng Lei Hu Wanbo Qu Chenglong Zhang Shurong Li Ziyu Liu Juncheng Liu Shengwu Guo Yu Xiao Zhibin Gao Zhen Zhang Yang Zhang Haijun Wu Stephen J.Pennycook Jun Sun Xiangdong Ding | 2023 | Interdisciplinary Materials2023，2，1： | 0 |
| 11 | Hopes in the Crisis——Chinese Automobile Market in the World Automanufacturing Industry Shuffle显示文摘Global automobile markets shuffle against the economic crisis The economic crisis spread rapidly around the world,making automobile industry one of the victims who are shocked hardest,leading to an industrial shuffle in global automobile industry. USA,EU and Japan,the traditional | Gao Shurong | 2009 | China's Foreign Trade2009，，17： | 0 |
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