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4篇 您的检索式：作者名="Simon Binder"

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		题名	作者	年代	出处	被引量
	1	Elevated concentrations of serum relaxin are associated with metastatic disease in breast cancer patients 显示文摘	Binder C Simon A Binder L	2004	Breast Cancer Res Treat2004，87，2：	1
	2	Elevated concentrations of serum relaxin are associated with metastatic disease in breast cancer patients显示文摘	Binder C Simon A Binder L	2004	Breast Cancer Res Treat2004，87，2：	1
	3	A prospective, randomised, multicenter trial for surgical treatment of central retinal vein occlusion: results of the Radial Optic Neurotomy for Central Vein Occlusion (ROVO) study group显示文摘	Tina Aggermann Simon Brunner Ilse Krebs Paulina Haas Irene Womastek Werner Brannath Susanne Binder	2013	Graefe’s Archive for Clinical and Experimental Ophthalmology2013，，4：	1
	4	Extravascular use of drug-eluting beads: A promising approach in compartment-based tumor therapy显示文摘Intraperitoneal carcinomatosis(PC)may occur with several tumor entities.The prognosis of patients suffering from PC is usually poor.Present treatment depends on the cancer entity and includes systemic chemotherapy,radiation therapy,hormonal therapy and surgical resection.Only few patients may also benefit from hyperthermic intraperitoneal chemotherapy with a complete tumor remission.These therapies are often accompanied by severe systemic side-effects.One approach to reduce side effects is to target chemotherapeutic agents to the tumor with carrier devices.Promising experimental results have been achieved using drug-eluting beads(DEBs).A series of in vitro and in vitro experiments has been conducted to determine the suitability of their extravascular use.These encapsulation devices were able to harbor CYP2B1producing cells and to shield them from the hosts immune system when injected intratumorally.In this way ifosfamide-which is transformed into its active metabolites by CYP2B1-could be successfully targeted into pancreatic tumor growths.Furthermore DEBs can be used to target chemotherapeutics into the abdominal cavity for treatment of PC.If CYP2B1 producing cells are proven to be save for usage in man and if local toxic effects of chemotherapeutics can be controlled,DEBs will become promising tools in compartmentbased anticancer treatment.	Simon Binder Andrew L Lewis J-Matthias Lhr Michael Keese	2013	World Journal of Gastroenterology2013，19，43：	0

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