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| 1 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 2 | Repeated operations for infiltrative low - grade gliomas without intervening therapy.显示文摘OBJECT:Progression of infiltrative low-grade gliomas(LGGs)has been reported previously.The limitations ofsuch studies include diverse histological grading systems,intervening therapy,and the lack of histological confir-mation of malignant tumor progression.The aim of this study was to determine tumor progression in adult patientswith an initial diagnosis of infiltrative LGG who subsequently underwent a repeated operation,but no other inter-vening therapy.The authors examined factors that may be associated with tumor progression. | Schmidt MH Berger MS Lamborn KR Aldape K McDermott MW Prados MD Chang SM | 2003 | 中国神经肿瘤杂志2003，1，2： | 8 |
| 3 | 妊娠期高血压疾病对远期心血管病的影响显示文摘对妇女妊娠期高血压疾病(hypertensive disorder of pregnancy,HDP)史的研究,可能有助于改善动脉粥样硬化性心血管病的风险评估。但是,有HDP既往史的中年无症状妇女在未来患心血管病的风险仍未知。该研究旨在探讨有或无HDP既往史的中年女性心血管病的远期发病率。纳入标准:在前瞻性、观察性英国生物资料库中,纳入40~69岁并至少有一活产的英国妇女,对其中一亚组妇女进行了无创性动脉硬度测量。 | 周卫(译) 叶鹏(摘、审校) Honigberg MC Zekavat SM Aragam K Klarin D Bhatt DL Scott NS Peloso GM Natarajan P | 2020 | 中华高血压杂志2020，28，2： | 6 |
| 4 | Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors显示文摘AIM:To investigate the expression and potential prognostic role of vascular endothelial growth factor(VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors(GEP-NETs) . METHODS:Microvessel density(MVD) in GEP-NETs was evaluated using endoglin and CD31 immunohistochemistry.In addition,tissue levels of endoglin and VEGF were determined in homogenates by ELISA. RESULTS:Endoglin was highly expressed on tumor endothelial cells.CD31 MVD in GEP-NETs was significantly higher compared to endoglin MVD(P<0.01) .Two-tofour-fold higher tissue levels of endoglin and VEGF were seen in tumors compared to associated normal tissue. This increased endoglin tissue expression in tumors was significantly related to tumor size(P<0.01) ,presence of metastases(P=0.04) ,and a more advanced tumor stage(P=0.02) ,whereas expression of VEGF was not. CONCLUSION:We suggest that endoglin is a potential marker to indicate and predict metastases,which might be useful in the post-resection therapeutic approach of patients with GEP-NETs. | Patricia Kuiper Lukas JAC Hawinkels Eveline SM de Jonge-Muller Izk Biemond Cornelis BHW Lamers Hein W Verspaget | 2011 | World Journal of Gastroenterology2011，17，2： | 4 |
| 5 | Interface Characterization of the SiCp/Al Composites Made by Powder Metallurgy显示文摘The interface of the SiCp/Al composites produced by powder metallurgy processing involving hotpressing above the matrix solidus temperature has been investigated by means of TEM. Several kinds of interfaces between the reinforcements and the matrix in the composite, including the clean interfaces, the faceted interfaces and the slight reaction intedeces, are presented. And most of interfaces belong to the slight reaction interfaces which are composed of the Al with different orientation from the Al matrix near the interface zone and particte-like substances produced by MgAl2O4 spinels and | Fan, JZ Zhang, K Shi, LK Zhang, SM | 1999 | Journal of Materials Science & Technology1999，15，2： | 2 |
| 6 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 7 | Pain management in mice using methanol extracts of three plants belongs to family Amaranthaceae显示文摘Objective:To investigate the analgesic activity of methanolic extract of Amaranthus viridis(A. viridis),Amaranthus caudatus(A.caudatus) and Amaranthus spinosus(A.spinosus).Methods:In this study,the analgesic activity of methanol extracts of all three plants at doses of 200 and 400 mg/kg were investigated by acetic acid-induced writhings test,hot plate test and tail immersion test for mice.Results:It was found that all the three plants showed significant pain management effect(P<0.01) at a dose of 400 mg/kg,but showed a less significant effect at a dose of 20 mg/kg in the entire tests used for evaluation of analgesic activities(P<0.05).Conclusions:Methanol extracts of A.viridis,A.caudatus and A.spinosus show potent analgesic activities,and this study provides the scientific proof for their traditional claims. | Ashok Kumar BS Lakshman K Jayaveera KN Vel Murgan C Arun Kumar PA Vinod Kumar R Meghda Hegade Sridhar SM | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 2 |
| 8 | Umbilical artery acid-base status in the preterm infant显示文摘 | Ramin SM Gilstrap LC Leveno K J Burris J Little BB | 1989 | Obstet Gynecol1989，74，2： | 1 |
| 9 | Withdrawal syndrome after the double-blind cessation of caffeine consumption显示文摘 | SILVERMAN K EVANS SM STRAIN EC | 1992 | N Engl J Med1992，327，16： | 1 |
| 10 | Neonatalbronchopulmonary dysplasia predicts abnormal pulmonaryHRCT scans in long-term survivors of extreme pretermbirth显示文摘 | Aukland SM Rosendahl K Owens CM | 2009 | Thorax2009，64，5： | 1 |
| 11 | Comparing electron microscopy and a competitive blocking ELISA in the detection of rotaviruses in porcine faeces显示文摘 | ROD(A)K L SM(I)TALOV(A) R (S)M(I)D B | 2009 | Vet J2009，187，2： | 1 |
| 12 | Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing显示文摘 | Harborth J Elbashir SM Beehert K | 2003 | Antisense Nucleic Acid Drug Dev2003，13，2： | 1 |
| 13 | Photodynamic actions of indocyanine green and trypan blue on human lens epithelial cells in vitro显示文摘 | Melendez RF Kumar N Maswadi SM Zaslow K Glickmank RD | 2005 | Am J Ophthalmol2005，140，1： | 1 |
| 14 | Portal vein and its tributaries:evaluation with thin-section three-dimensional contrast-enhanced dynamic fat-suppressed MR imaging显示文摘 | Ito K Blasbalg R Hussain SM | 2000 | Radiology2000，215，2： | 1 |
| 15 | Combination of in vitro bioassays encompassing different mechanisms to determine the endocrinedisrupting effects of river water显示文摘 | Oh SM Park K Chung KH | 2006 | Sci Total environ2006，354，23： | 1 |
| 16 | Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man 显示文摘 | Tuschl K Clayton PT Gospe SM Jr | 2012 | Am J Hum Genet2012，90，： | 1 |
| 17 | Accuracy of muhidetector CT scans in staging of renal carcinoma显示文摘 | Nazim SM Ather MH Hafeez K | 2011 | Int J Surg2011，9，1： | 1 |
| 18 | The gene responsible for X-linked cleft palate (CPX) in a British Columbia native kindred is localized between PGK1 and DXYSI显示文摘 | Gorski SM Adams K J Birch PH | 1992 | Am J Hum Genet1992，50，5： | 1 |
| 19 | Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Thl-type immunity显示文摘 | Dredge K Marriott JB Todryk SM | 2002 | J Immunol2002，168，10： | 1 |
| 20 | Opposing regulation of the locus encoding IL-17 through diroet, reciprocal actions of STAT3 and STATS显示文摘 | Yang XP C horesehi K Steward-11ua-p SM | 2011 | Nat Immunol2011，12，3： | 1 |
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