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462篇 您的检索式:作者名="Smith DR"
    题名 作者 年代 出处 被引量
1全球听力障碍的现状及对策——WHO关于听障问题的白皮书简介显示文摘Dr Andrew Smith 王树峰 2004中国听力语言康复科学杂志2004,,6:24
2p53 cDNA突变和突变型p53蛋白表达与大肠癌预后的关系显示文摘目的 探讨p53基因cDNA突变和突变型p53基因蛋白表达与大肠腺癌预后的关系。方法 RT-PCR-SSCP检测大肠腺癌组织p53基因cDNA突变,PAb240单抗免疫组化检测大肠腺癌组织突变型p53基因蛋白表达,比较两者与大肠腺癌预后的关系。结果 100例大肠腺癌中,p53基因cDNA突变51例(51%),突变型p53基因蛋白高表达76例(76%),两者同步阳性49例;p53基因cDNA突变与突变型p53基因蛋白高表达相关,有显著统计学差异(P<0.01);与Dukes分期无关(P>0.05)。从Kaplan-Meier 生存曲线和log-rank 分析结果看,突变型p53基因蛋白高表达与大肠腺癌预后无显著统计学差异(P=0.72);p53基因cDNA突变与大肠腺癌预后有关,统计学差异明显 (P=0.03)。结论 p53基因cDNA突变与突变型p53基因蛋白高表达密切相关。高频率p53基因cDNA突变直接反映大肠腺癌预后差。突变型p53基因高表达则可能受多因素影响,不能直接反映大肠腺癌预后。季晨阳 季 丹 DR Smith HS Goh 2000第一军医大学学报2000,20,5:2
3Auricular acunpuncture for cocaine dependence 显示文摘Gates S Smith LA Foxcroft DR 2006Cochrane Database Syst Rev2006,25,00:1
4Polymorphisms in ghrelin and neuropeptide Y genes are associated with non-Hodgkin lymphoma显示文摘Skibola DR Smith MT Bricci PM 2005Cancer Epidemiol Biomarkers Prey2005,14,5:1
5Identification of human skeletal remains by comparison of bony details of the cranium using computerized tomographic(CT) scas显示文摘Smith DR Limbird KG 2002J Forensic Sci2002,47,5:1
6Three-dimensional structure of myosin subfragment-1 : a molecular motor显示文摘Rayment I Rypniewski WR Schmidt-Base K Smith R Tomchik DR Benning MM Winkelmann DA Wesenberg G Holden HM 1993Science1993,261,:1
7Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis显示文摘Liu Y Smith PW Jones DR 2006Mol Cell Biol2006,26,23:1
8Blood carbon monoxide and hydrogen cyanide concentrations in the fatalities of fire and non-fire associated civil aviation accidents,1991-1998显示文摘Chaturvedi AK Smith DR Canfield CV 2001Forensic Science International2001,121,:1
9Cardiovascular responses following laryngoscope assisted, fibreoptic orotracheal intubation 显示文摘Tong JL Ashworth DR Smith JE 2005Anaesthesia2005,60,8:1
10Postoperative neuromuscular blockade;a comparision between atracurium,vecuronium and pancuroniumi显示文摘Bevan DR Smith CE Donati F 1988Anesthesiology1988,69,:1
11Retinoids in cancer therapy 显示文摘Smith ME Parkingson DR Cheson BD 1992J Clin Oncol1992,10,:1
12Exhaled nitric oxide measurements, clinical application and interpretation 显示文摘Taylor DR Pijnenburg MW Smith AD 2006Thorax2006,61,9:1
13Early detection of asthma ex- acerbations by using action points in self-management plans显示文摘Honkoop P J Taylor DR Smith AD 2013Eur Respir J2013,41,1:1
14Trans-retinoic acid and related differentiation agents显示文摘Parkinson DR Smith MA Cheson BD 1992Semin Oncol1992,19,6:1
15Physicians Expectations of pharmacists显示文摘William ES Smith Max DR 2002American Journal Health - System Pharmacy2002,59,:1
16Effect of topical lignocaine on the sympathoadrenal responses to tracheal intubation 显示文摘Derbyshire DR Smith G Achola KJ 1987Br J Anaesth1987,59,2:1
17Meningiomas in Singapore: demographic and biological characteristics显示文摘Das A Tang WY Smith DR 2000J Neurooncol2000,47,:1
18Animal models of viral hemorrhagic fever显示文摘Smith DR Holbrook MR Gowen BB 2014Antiviral Res2014,112,:1
19Single-target molecule detection with nonbleaching multicolor optical immunolabels显示文摘Schuhz S Smith DR Mock JJ 2000Proceeding of the National Academy of Sciences of the United States of America2000,97,3:1
20Exhaled nitric oxide measurements:clinical application and interpretation显示文摘Taylor DR Pijnenburg MW Smith AD 2006Thorax2006,61,9:1
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