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| 1 | 东亚零部件贸易影响因素及特点分析:基于引力模型的测算(1992~2006)显示文摘本文根据Jones等人提出的国际垂直分割理论,建立增广引力模型。在区分零部件贸易和传统贸易的情况下,我们利用联合国贸易统计数据,分析了1992~2006年间东亚生产共享和零部件贸易的规模、结构及其变迁情况。我们采用面板数据固定效应两步回归法,揭示了东亚区域内部一体化组织和国家,特别是中国对生产网络的贡献。结果显示,相对于传统贸易,国际直接投资的增加、双边关税及服务联系成本的降低对零部件贸易起到更显著的促进作用。同时,伴随着垂直分工模式的变迁,东亚产业链表现出很强的完整性和不可分割性,技术水平的衔接性在东亚分工格局中起到重要作用。 | 陈静 Somnath Sen 胡昭玲 白雪飞 | 2009 | 世界经济2009，32，11： | 22 |
| 2 | Portal biliopathy显示文摘Biliary ductal changes are a common radiological finding in patients with portal hypertension, however only a small percentage of patients (5%-30%) develop symptomatic bile duct obstruction. The exact pathogenesis is not clear, but an involvement of factors such as bile duct compression by venous collaterals, ischemia, and infection is accepted by most authors. Although endoscopic retrograde cholangiopancrea- tography was used to define and diagnose this condition, magnetic resonance cholangiopancreatography is currently the investigation of choice for diagnosing this condition. Treatment is indicated only for symptomatic cases. Portosystemic shunts are the treatment of choice for symptomatic portal biliopathy. In the majority of patients, the changes caused by biliopathy resolve after shunt surgery, however, 15%-20% patients require a subsequent bilio-enteric bypass or endoscopic management for persistent biliopathy. There is a role for endoscopic therapy in patients with bile duct stones, cholangitis or when portosystemic shunt surgery is not feasible. | Somnath Chattopadhyay Samiran Nundy | 2012 | World Journal of Gastroenterology2012，18，43： | 9 |
| 3 | Effects of contact lens wearing on keratoconus:a confocal microscopy observation显示文摘AIM: To evaluate the corneal cell morphology of new keratoconus patients wearing two different types of rigid gas-permeable(RGP) contact lenses for 1y.METHODS: Thirty nine eyes of 39 new keratoconus patients were selected and randomly fitted with two types of RGP contact lenses.Group 1 had 21 eyes with regular rigid gas-permeable(RRGP) contact lens and rest 18 eyes were in group 2 with specially designed rigid gas-permeable(SRGP) contact lens.Corneal cell morphology was evaluated using a slit scanning confocal microscope at no-lens wear and after 1y of contact lens wearing.RESULTS: After 1y of contact lens wearing in group 1,the mean anterior and posterior stromal keratocyte density were significantly less(P=0.006 and P=0.001,respectively) compared to no-lens wear.The mean cell area of anterior and posterior stromal keratocyte were also significantly different(P=0.005 and P=0.001) from no-lens wear.The anterior and posterior stromal haze increased by 18.74% and 23.81%,respectively after 1y of contact lens wearing.Whereas in group 2,statistically significant changes were observed only in cell density & area of anterior stroma(P=0.001 and P=0.001,respectively) after 1y.While,level of anterior and posterior stromal haze increased by 16.67% and 11.11% after 1y of contact lens wearing.Polymegathism and pleomorphism also increased after 1y of contact lens wearing in both the contact lens groups.CONCLUSION: Confocal microscopy observation shows the significant alterations in corneal cell morphology of keratoconic corneas wearing contact lenses especially in group 1.The type of contact lens must be carefully selected to minimize changes in corneal cell morphology. | Somnath Ghosh Haliza A Mutalib Sharanjeet Kaur Rituparna Ghoshal Shamala Retnasabapathy | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 4 |
| 4 | Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers显示文摘OBJECTIVE Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma(HNSCC).In the present study,we investigated whether garcinol,apolyisoprenylated benzophenone can chemosensitize HNSCC to cisplatin.METHODS The effect of garcinol and cisplatin on HNSCC was assessed by MTT,Western blotting,real time PCR,FACS,immunohistochemistry,DNA binding assay and xenograft mouse model.RESULTS We found that garcinol inhibited the viability of a panel of diverse HNSCC cell lines,enhanced the apoptotic effect of cisplatin,suppressed constitutive as well as cisplatin-induced NF-κB activation,and downregulated the expression of various oncogenic gene products(cyclin D1,Bcl-2,survivin and VEGF).In vivo study showed that administration of garcinol alone(0.5 mg·kg-1,ip five times/week)significantly suppressed the growth of the tumor,and this effect was further increased by cisplatin.Both the markers of proliferation index(Ki-67)and microvessel density(CD31)were downregulated in tumor tissues by the combination of cisplatin and garcinol.The pharmacokinetic results of garcinol indicated that good systemic exposure was achievable after ip administration of garcinol at 0.5and 2mg·kg-1 with mean peak concentration(cmax)of 1825.4 and 6635.7nmol·L-1 in the mouse serum,respectively.CONCLUSION Overall,our results suggest that garcinol can indeed potentiate the effects of cisplatin by negative regulation of various inflammatory and proliferative biomarkers. | Feng Li Muthu K. Shanmugam Kodappully Sivaraman Siveen Fan Wang Tina H. Ong Ser Yue Loo Mahadeva M.M. Swamy Somnath Mandal Alan Prem Kumar Boon Cher Goh Tapas Kundu Kwang Seok Ahn Ling Zhi Wang Kam Man Hui Gautam Sethi | 2015 | 中国药理学与毒理学杂志2015，29，S1： | 4 |
| 5 | 东亚垂直分工网络与技术梯度研究——基于零部件贸易的视角显示文摘东亚因其迅速发展的国际生产网络而得到经济学界的广泛瞩目。本文在整理相关理论和实证文献的基础上,通过对人均收入水平的分析提出了东亚区域内广泛存在技术梯度差异的现实。作者根据Jones等人提出的国际垂直分割理论,建立增广引力模型,在区分零部件贸易和传统贸易的情况下,利用联合国贸易统计面板数据,对东亚垂直分工网络的技术结构进行了细致梳理。结果显示,近年来日本在核心部件上的作用有所下降,而四小龙实现了技术升级,作用得到较大的提升。作为东亚生产共享网络中的重要一极,中国同四小虎之间呈现出较强的互补性而非替代性。 | 刘重力 陈静 Somnath Sen 白雪飞 | 2009 | 世界经济研究2009，，6： | 4 |
| 6 | 将临床测量表与ICF类目建立联系的规则:从研究实例说明规则的更新显示文摘结局研究的目的是了解卫生服务的最终结果。研究人员使用了包括技术、临床和患者导向的大量的结局测量方法。将《国际功能、残疾和健康分类》(ICF)作为通用的关于功能的参考架构,有助于促进结局研究。本文目的是提供Cieza等2002年发表的《国际功能、残疾和健康分类》(ICF)联系规则的更新版本,并以实例说明如何应用这些规则联系技术将临床测量方法、健康状况测量方法以及干预措施与ICF相关联。我们已建立了关于健康状况测量方法与ICF相联系的3种具体联系规则,而另一种具体联系规则是用于技术、临床测量方法以及干预措施与ICF之间建立联系。总共建立了8种联系规则既可用于所有不同的结局测量方法,又可用于各种干预措施。最近更新的联系规则使得研究者能够系统地联系和比较其中涵盖的有意义的概念。在大量的用于干预措施的备选测量方法中选择最恰当的结局测量方法,联系规则被证明是非常有用的。进一步可能的应用是使用特定的测量方法或基于ICF类目建立的项目数据库使得具体的ICF类目可操作化。 | Alarcos Cieza Szilvia Geyh Somnath Chatterji Nenad Kostanjsek Bedirhan stün Gerold Stucki 吴丽慧 李沁燚 邱卓英 蔡飞鸣 | 2011 | 中国康复理论与实践2011，17，2： | 4 |
| 7 | Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial显示文摘 | Somnath Mukherjee Christopher N Hurt John Bridgewater Stephen Falk Sebastian Cummins Harpreet Wasan Tom Crosby Catherine Jephcott Rajarshi Roy Ganesh Radhakrishna Alec McDonald Ruby Ray George Joseph John Staffurth Ross A Abrams Gareth Griffiths Tim Maugh | 2013 | Lancet Oncology2013，，4： | 4 |
| 8 | Application of seminal germ cell morphology and semen biochemistry in the diagnosis and management of azoospermic subjects显示文摘To evaluate whether the study of seminal germ cell morphology (SGCM) and semen biochemistry could be fruitfully utilized for the diagnosis and management of azoospermic subjects. Methods: In the semen, mature and immature germ cells are contributed by the testes, 70% of glycerylphosphoryl choline (GPC) by the epididymis, fructose mostly or solely by the seminal vesicles and acid phosphate (ACP) by the prostate. In 16 normal volunteers, 12vasectomized subjects and 186 azoospermic subjects, these parameters have been studied and the data have been analyzed. Results: Both mature and immature germ cells are absent in the semen of vasectomized subjects as well as in obstructive azoospermia; GPC level is also significantly decreased in both these groups. In cases with non-obstructive azoospermia immature germ cells are present and seminal GPC, ACP and fructose levels are normal. The diagnosis of obstructive and non-obstructive azoospermia based on these parameters correlated well with 'correct' testicular biopsy findings. In some cases of azoospermia due to hypospermatogenesis or spermatogenic developmental arrest, the SGCM studies were very helpful in objectively monitoring the response of the germinal tissue to specific treatments. Conclusion: SGCM and semen biochemical parameters are very valuable non-invasive markers for differentiating obstructive from non-obstructive azoospermia. The SGCM findings serve as a dependable non-invasive testicular marker with high predictive value. | Somnath Roy A.Banerjee H.C.Pandey G.Singh G.L.Kumari | 2001 | Asian Journal of Andrology2001，3，1： | 4 |
| 9 | Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver显示文摘Dear Editor,The sodium taurocholate(TC)co-transporting polypeptide NTCP(SLC10A1)is a secondary active membrane transport protein that mediates the uptake of bile salts from the portal blood plasma into the cytoplasm of liver cells.NTCP was originally cloned from rat and demonstrated to be localized in the basolateral membrane.1 Its activity is a key component of bile acid homeostasis and enterohepatic circulation of bile salts(Fig.1a),a process that includes at least three additional transporter proteins,namely BSEP,ASBT and OSTα/β.2,3 In addition to its role in mediating bile salt uptake,NTCP also serves as the receptor of the human hepatitis B and D viruses.4 The mechanism by which NTCP recognizes and transports bile salts is not understood,in part because no structural insight into the interaction of NTCP with its substrates is available.While recent studies reported structures of NTCP bound to inhibitory nanobodies5 or Fab fragments,6,7 no substrate-binding pockets were identified. | Hongtao Liu Rossitza N.Irobalieva Rose Bang-Sørensen Kamil Nosol Somnath Mukherjee Parth Agrawal Bruno Stieger Anthony A.Kossiakoff Kaspar P.Locher | 2022 | Cell Research2022，32，8： | 2 |
| 10 | Development of a mixed fruit beverage and pulsed light treatment thereof to obtain a microbially safe and enzymatically stable product显示文摘A mixed fruit beverage was formulated according to D-optimal mixture design using apple ber juice(X_(1),45-59%v/v)-an underexplored fruit,carambola juice(X_(2),1-20%v/v),and black table grape juice(X3,35-40%v/v).The crisp overall acceptability(COA)from 16 semi-trained panelists and overall hedonic score(OSH)from consumers were estimated.The best formulation was apple ber:carambola:black table grape juices=59.0:3.5:37.5 v/v with COA and OSH values of 3.23(on a scale of 5)and 7.55(on a scale of 9),respectively.Further,the efficacy of pulsed light(PL)(18-30 W cm^(-2) for 33-167 s;total fluence 600-5000 J cm^(-2))and thermal treatments(90℃ for 1-5 min)were studied on various attributes of the mixed beverage.The beverages processed at 90℃ for 5 min(thermal treatment)and 5000 J cm^(-2)(PL treatment at 30 W cm^(-2) for 167 s)showed no microbial count with a complete enzyme inactivation.The thermally pasteurized sample(90℃/5 min)was more brown(browning index=70.15)than the PL pasteurized beverage(browning index=65.98).Interestingly,the PL pasteurized(5000 J cm^(-2))beverage showed 25%,27%,and 19% more vitamin C,antioxidants,and phenolic compounds,respectively,than the thermally pasteurized(90℃/5 min)beverage.The PL-treated beverage had a greater sensory appeal than the thermally treated beverage.PL-treatment can be an efficient non-thermal pasteurization treatment for ensuring complete microbial and enzymatic inactivation with maximal retention of nutritional and sensory attributes of the blended beverage. | Snehasis Chakraborty Sagar Mahale Rishab Dhar Somnath Basak | 2022 | Food Bioscience2022，45，1： | 2 |
| 11 | Performance study and kinetic modeling of hybrid bioreactor for treatment of bi-substrate mixture of phenol-m-cresol in wastewater:Process optimization with response surface methodology显示文摘Performance of a hybrid reactor comprising of trickling filter(TF) and aeration tank(AT) unit was studied for biological treatment of wastewater containing mixture of phenol and m-cresol,using mixed microbial culture.The reactor was operated with hydraulic loading rates(HLR) and phenolics loading rates(PLR) between 0.222-1.078m3/(m2·day) and 0.900-3.456kg/(m3·day),respectively.The efficiency of substrate removal varied between 71%-100% for the range of HLR and PLR studied.The fixed film unit showed better substrate removal efficiency than the aeration tank and was more resistant to substrate inhibition.The kinetic parameters related to both units of the reactor were evaluated and their variation with HLR and PLR were monitored.It revealed the presence of substrate inhibition at high PLR both in TF and AT unit.The biofilm model established the substrate concentration profile within the film by solving differential equation of substrate mass transfer using boundary problem solver tool 'bvp4c' of MATLAB 7.1 software.Response surface methodology was used to design and optimize the biodegradation process using Design Expert 8 software,where phenol and m-cresol concentrations,residence time were chosen as input variables and percentage of removal was the response.The design of experiment showed that a quadratic model could be fitted best for the present experimental study.Significant interaction of the residence time with the substrate concentrations was observed.The optimized condition for operating the reactor as predicted by the model was 230mg/L of phenol,190mg/L of m-cresol with residence time of 24.82 hr to achieve 99.92% substrate removal. | Sudipta Dey Somnath Mukherjee | 2013 | Journal of Environmental Sciences2013，25，4： | 2 |
| 12 | Theory,instrumentation and applications of magnetoelastic resonance sensors:a review显示文摘 | CRAIG A G SOMNATH C R SANJU R | 2011 | Sensors2011，11，3： | 1 |
| 13 | Mufti-signal flow graphs:a novel approach for system testability analysis and fault diagnosis显示文摘 | Somnath Deb Krishna R P Vijay R | 1995 | IEEE Aerospace and Electronics Magazine1995，10，5： | 1 |
| 14 | Improvement on the Multihop Shareholder Discovery for Threshold Secret Sharing in MANETs显示文摘The collaboration of at least a threshold number of secret shareholders in a threshold secret sharing scheme is a strict requirement to ensure its intended functionality.Due to its promising characteristics,such a scheme has been proposed to solve a range of security problems in mobile ad hoc networks.However,discovering a sufficient number of secret shareholders in such dynamic and unpredictable networks is not easy.In this paper,we propose a more efficient shareholder discovery mechanism compared to our previous work.The discovery process is performed in a multihop fashion to adapt to the mobile ad hoc network environment.We introduce batch extension that gradually extends the shareholders' collaboration boundary by more than one hop at a time around the service requestor,to find at least the threshold number of the unknown shareholders.Through the batch extension,reply aggregation is applicable,hence reducing the redundancy use of reply routes,decreasing the required packet transmission,and lessening the service delay,compared to the previously proposed mechanism.Our simulation results show that,with the appropriate batch size,the latest mechanism is more efficient with an insignificant increase of control overhead. | Seleviawati Tarmizi Prakash Veeraraghavan Somnath Ghosh | 2011 | Journal of Computer Science & Technology2011，26，4： | 1 |
| 15 | Proteomics based prediction of antigenicity ofiberiotoxin from eastem Indian scorpion显示文摘 | Gomase VS Phadnis AC Somnath W | 2009 | Internation- al Journal of Drug Discovery2009，1，1： | 1 |
| 16 | Computationally efficient algorithms for multiple fault diagnosis in large graph-based systems显示文摘 | Fang Tu Krishna R P Somnath Deb | 2003 | IEEE Trans on SMC2003，33，1： | 1 |
| 17 | Multisignal flow graphs: A novel approach for system testability analysis and fault diagnosis显示文摘 | Somnath Deb Krishna R Vijay Raghavan | 1995 | IEEE AES systems magazine1995，，5： | 1 |
| 18 | The role of phase impurities and lattice defects on the electron dynamics and photochemistry of CuFeO2 solar photocathodes显示文摘CuFeO2 is a promising photocathode for H2 evolution and CO2 reduction reactions.To better understand the complex defect chemistry and role of impurity phases in this material and their effect on the photochemical performance,we employ visible light transient absorption spectroscopy and density functional theory(DFT)calculations to investigate the electron dynamics in electrochemically deposited Cu-Fe oxide thin films.Kinetic analysis of carrier lifetime shows a fast,sub-ps contribution to relaxation followed by persistence of a Iong-lived state to time delays greater than 2 ns.Increasing amplitude of the Iong-lived state is shown to correlate with the rate of fast initial relaxation,and this is explained in terms of a competition between charge carrier trapping and charge separation.Charge separation in CuFeO2 occurs via hole thermalizati on from O 2p to Cu 3d vale nee band states leadi ng to segregatio n of electr ons and holes across layers in the CuFeO2 lattice.Correlation between transient absorption measurements and DFT calculations suggest that Cu vacancies enhanee photochemical performance by facilitating charge separation kinetics.In contrast,O interstitials are predicted to switch the relative positions of O 2p and Cu 3d vale nee band states,which would in hibit charge separatio n by in ter-band hole thermal izatio n.Fin ally,we find no evide nee for electron in jecti on from CuFeO2 to CuO suggest!ng that charge separati on at this heterostructure in terface does not play a role in the carrier lifetime or photochemical performance of the catalysts studied here. | Elizabeth A. Fugate Somnath Biswas Mathew C. Clement Minkyu Kim Dongjoon Kim Aravind Asthagiri L. Robert Baker | 2019 | Nano Research2019，12，9： | 1 |
| 19 | A new relaxation algorithm and passive sensor data association显示文摘 | Krishna R Pattipati Somnath Deb Yaakov Bar-Shalom | 1992 | IEEE Trans on Automatic Control1992，37，2： | 1 |
| 20 | A generalized S-D assignment algorithm for multisensor-multitarget state estimation显示文摘 | Somnath Deb Murali Yeddanapudi Krishna R Pattipati | 1997 | IEEE Trans on AES1997，33，2： | 1 |
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