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| 1 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang Yu Wenbing | 2002 | Cold Regions Science and Technology2002，，1： | 4 |
| 2 | Approxinmate analutical solutiong for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang etc | 2002 | Cold Regions Science and Technology2002，34，： | 1 |
| 3 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang Yu Wenbing | 2002 | Cold Regions Science and Technology2002，，1： | 1 |
| 4 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | LAI Yuanming LIU Songyu WU Ziwang | 2002 | Cold Regions Science and Technology2002，34，： | 1 |
| 5 | Genome-wide analysis of Aux/IAA gene family in Solanaceae species using tomato as a model 显示文摘 | WU Jian PENG Zhen LIU Songyu | 2012 | Mol Genet Genomics2012，287，4： | 1 |
| 6 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang Yu Wenbing | 2002 | Cold Regions Science and Technology2002，，1： | 1 |
| 7 | Approximate analytical solution for temperature fields in cold regiom circular tunnels 显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang etc | 2002 | Cold Regions Science and Technology 342002，4349，： | 1 |
| 8 | Genome-wide analysis of the mitogen-activated protein kinase gene family in Solanum lycopersicum显示文摘 | Fuling Kong Jie Wang Lin Cheng Songyu Liu Jian Wu Zhen Peng Gang Lu | 2012 | Gene2012，，： | 1 |
| 9 | Analytical viscoelastic solution for frost force in cold-region tunnels显示文摘 | Yuanming Lai Wu Hui Wu Ziwang Liu Songyu Den Xuejun | 2000 | Cold Regions Science and Technology2000，，3： | 1 |
| 10 | Study on macro and micro shear strength of continuously graded and gap-graded sand显示文摘The particle gradation of sand has a significant influence on its shear strength,yet the similarities and differences between the effects of continuous and gap grading have yet to be fully explored.In this study,the discrete element method(DEM)was used to simulate biaxial tests on granular samples that were both continuously graded and gap-graded.The macroscopic analysis revealed that the shear strength of continuously graded sands increases initially and then decreases as the uniformity of particle size distribution decreases.On the other hand,the lack of medium particles in gap-graded sands amplifies the difference in particle size between coarse and fine particles,leading to a decrease in shear strength.Microscopically,both continuous and gap gradings affect the internal packing structure of the particle assembly,which consequently affects particle stress distributions,contact forces,coordination numbers,stress-induced anisotropies,and contact force networks,thus having an impact on the macroscopic shear strength.The global uniformity of particle size distribution was unidirectionally affected by continuous grading,while gap grading had a locally bidirectional influence.These findings provide a better understanding of the effects of particle grading on the macroscopic shear strength of sands. | Peiran Zhao Songyu Liu Kai Wu | 2024 | Particuology2024，86，3： | 0 |
| 11 | A DNA-based nanocarrier for efficient cancer therapy显示文摘The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread(CPT-DNA-NT),mediated by scavenger receptors into HeLa cells.DNA-NT was developed with stiff-topology utilizing circular-scaffold to encapsulate CPT.Atomic force microscopy(AFM)characterization of the DNA-NT showed uniformity in the structure with a diameter of 50-150 nm and length of 300-600 nm.The successful fabrication of the DNA-NT was confirmed through native-polyacrylamide gel electrophoresis analysis,as large the molecular-weight(polymeric)DNA-NT did not split into constituting strands under applied current and voltage.The results of cell viability confirmed that blank DNA-NT had the least cytotoxicity at the highest concentration(512 nM)with a viability of 92%as evidence of its biocompatibility for drug delivery.MTT assay showed superior cytotoxicity of CPT-DNA-NT than that of the free CPT due to the depot release of CPT after DNA-NT internalization.The DNA-NT exhibited targeted cell internalizations with the controlled intracellular release of CPT(from DNA-NT),as illustrated in confocal images.Therefore,in vitro cytotoxicity assessment through flow cytometry showed enhanced apoptosis(72.7%)with CPT-DNA-NT(compared to free CPT;64.4%).CPT-DNA-NT,being poly-anionic,showed enhanced endocytosis via scavenger receptors. | Muhammad Abbas Mirza Muhammad Faran Ashraf Baig Yaliang Zhang Yu-Shun Yang Songyu Wu Yiqiao Hu Zhong-Chang Wang Hai-Liang Zhu | 2021 | Journal of Pharmaceutical Analysis2021，11，3： | 0 |
| 12 | Growth of centimeter scale Nb_(1−x)W_(x)Se_(2) monolayer film by promoter assisted liquid phase chemical vapor deposition显示文摘Two-dimensional(2D)transition-metal dichalcogenide materials(TMDs)alloys have a wide range of applications in the field of optoelectronics due to their capacity to achieve wide modulation of the band gap with fully tunable compositions.However,it is still a challenge for growing alloys with uniform components and large lateral size due to the random distribution of the crystal nucleus locations.Here,we applied a simple but effective promoter assisted liquid phase chemical vapor deposition(CVD)method,in which the quantity ratio of promoter to metal precursor can be controlled precisely,leading to tiny amounts of transition metal oxide precursors deposition onto the substrates in a highly uniform and reproducible manner,which can effectively control the uniform distribution of element components and nucleation sites.By this method,a series of monolayer Nb_(1−x)W_(x)Se_(2)alloy films with fully tunable compositions and centimeter scale have been successfully synthesized on sapphire substrates.This controllable approach opens a new way to produce large area and uniform 2D alloy film,which has the potential for the construction of optoelectronic devices with tailored spectral responses. | Boxing An Yang Ma Feihong Chu Xuhong Li Yi Wu Congya You Wenjie Deng Songyu Li Yongzhe Zhang | 2022 | Nano Research2022，15，3： | 0 |
| 13 | Nanofiber self-consistent additive manufacturing process for 3D microfluidics显示文摘3D microfluidic devices have emerged as powerful platforms for analytical chemistry,biomedical sensors,and microscale fluid manipulation.3D printing technology,owing to its structural fabrication flexibility,has drawn extensive attention in the field of 3D microfluidics fabrication.However,the collapse of suspended structures and residues of sacrificial materials greatly restrict the application of this technology,especially for extremely narrow channel fabrication.In this paper,a 3D printing strategy named nanofiber self-consistent additive manufacturing(NSCAM)is proposed for integrated 3D microfluidic chip fabrication with porous nanofibers as supporting structures,which avoids the sacrificial layer release process.In the NSCAM process,electrospinning and electrohydrodynamic jet(E-jet)writing are alternately employed.The porous polyimide nanofiber mats formed by electrospinning are ingeniously applied as both supporting structures for the suspended layer and percolating media for liquid flow,while the polydimethylsiloxane E-jet writing ink printed on the nanofiber mats(named construction fluid in this paper)controllably permeates through the porous mats.After curing,the resultant construction fluid–nanofiber composites are formed as 3D channel walls.As a proof of concept,a microfluidic pressure-gain valve,which contains typical features of narrow channels and movable membranes,was fabricated,and the printed valve was totally closed under a control pressure of 45 kPa with a fast dynamic response of 52.6 ms,indicating the feasibility of NSCAM.Therefore,we believe NSCAM is a promising technique for manufacturing microdevices that include movable membrane cavities,pillar cavities,and porous scaffolds,showing broad applications in 3D microfluidics,soft robot drivers or sensors,and organ-on-a-chip systems. | Bin Qiu Xiaojun Chen Feng Xu Dongyang Wu Yike Zhou Wenchang Tu Hang Jin Gonghan He Songyue Chen Daoheng Sun | 2022 | Microsystems & Nanoengineering2022，8，5： | 0 |
| 14 | Binary-ternary transition metal chalcogenides interlayer coupling in van der Waals type-II heterostructure for visible-infrared photodetector with efficient suppression dark currents显示文摘Ternary two-dimentional(2D)materials exhibit diverse physical properties depending on their composition,structure,and thickness.Through forming heterostructures with other binary materials that show similar structure,there can be numerous potential applications of these ternary 2D materials.In this work,we reported the structure of few-layer CrPS_(4)by X-ray diffraction,transmission electron microscope,and electron-density distribution calculation.We also demonstrated a new application of the CrPS_(4)/MoS_(2)heterobilayer:visible-infrared photodetectors with type-II staggered band alignment at room temperature.The response of the heterostructure to infrared light results from a strong interlayer coupling that reduces the energy interval in the junction area.Since the intrinsic bandgap of individual components determines wavelengths,the decrease in energy interval allows better detection of light that has a longer wavelength.We used photoluminescence(PL)spectroscopy,Kelvin probe force microscopy(KPFM)under illumination,and electrical transport measurements to verify the photoinduced charge separation between the CrPS_(4)/MoS_(2)heterostructures.At forward bias,the device functioned as a highly sensitive photodetector,as the wavelength-dependent photocurrent measurement achieved the observation of optical excitation from 532 to 1,450 nm wavelength.Moreover,the photocurrent caused by interlayer exciton reached around 1.2 nA at 1,095 nm wavelength.Our demonstration of the strong interlayer coupling in the CrPS_(4)/MoS_(2)heterostructure may further the understanding of the essential physics behind binary-ternary transition metal chalcogenides heterostructure and pave a way for their potential applications in visible-infrared devices. | Guoliang Xu Danmin Liu Songyu Li Yi Wu Zhenlu Zhang Shaobo Wang Zikun Huang Yongzhe Zhang | 2022 | Nano Research2022，15，3： | 0 |
| 15 | Mechanism of action of cordycepin in the treatment of hepatocellular carcinoma via regulation of the Hippo signaling pathway显示文摘Hepatocellular carcinoma(HCC)is one of the common most malignant tumors.This study aimed to determine the in vitro and in vivo anticancer activity of cordycepin and elucidate its mechanism of action.The results of in vitro and in vivo studies revealed that cordycepin inhibited proliferation and migration in HepG-2 cells and inhibited the growth of HepG-2 xenograft-bearing nude mice by inducing apoptosis.Transcriptome sequencing analysis revealed a total of 403 differential genes,which revealed that cordycepin may play an anti-HCC role by regulating Hippo signaling pathway.The regulatory effects of cordycepin on the Hippo signaling pathway was further investigated using a YAP1 inhibitor.The results demonstrated that cordycepin upregulated the expression of MST1 and LAST1,and subsequently inhibited YAP1,which activated the Hippo signaling pathway.This in turn downregulated the expression of GBP3 and ETV5,and subsequently inhibited cell proliferation and migration.Additionally,YAP1 regulated the expression of Bax and Bcl-2,regulated the mitochondrial apoptotic pathway,and induced apoptosis by upregulating the expression of the caspase-3 protein.In summary,this study reveals that cordycepin exerts its anti-hepatocarcinoma effect through regulating Hippo signaling pathway,and GBP3 and ETV5 may be potential therapeutic targets for hepatocarcinoma. | Xiaomin Li Qing Liu Songyu Xie Xiaoping Wu Junsheng Fu | 2024 | Food Science and Human Wellness2024，13，2： | 0 |
| 16 | CMOS-compatible retinomorphic Si photodetector for motion detection显示文摘Efficient motion detection is essential for the Internet of Things.However,it suffers from overloading redundant static background information.Inspired by the human visual system,which is efficient in motion detection,we propose a silicon-based retinomorphic photodetector with a simple metal/insulator/semiconductor(MIS)structure,which is compatible with the complementary metal-oxide-semiconductor(CMOS)industry.In contrast to conventional photodetectors that generate a sustained photocurrent,our retinomorphic photodetector is sensitive only to the change in light intensity and therefore filters the redundant static background.In addition,it shows logarithmic dependence on the light intensity,which simplifies the contrast ratio measurement.Based on our moving object recognition experiment,after filtering background information,the information to be analyzed is reduced to 27.3%,thereby improving the image recognition efficiency in the subsequent processing tasks.This innovative and industry-compatible retinomorphic photodetector will facilitate the construction of future efficient motion detection systems. | Yi WU Wenjie DENG Xiaoqing CHEN Jingjie LI Songyu LI Yongzhe ZHANG | 2023 | Science China(Information Sciences)2023，66，6： | 0 |
| 17 | Influence of aspect ratio and arrangement direction on the shear behavior of ellipsoids显示文摘This work studies the macroscopic and microscopic behaviors of ellipsoids under triaxial tests using 3D discrete element method(DEM)simulation.To avoid the boundary effect,a novel stress servo-controlled periodic boundary condition is proposed to maintain the confining pressure of samples during testing.The shape features of ellipsoids are investigated,including the aspect ratio of elongated/oblate ellipsoids and the initial arrangement directions of ellipsoids.The macroscopic properties of ellipsoidal particle samples,such as the deviatoric stress,volumetric strain,internal friction angle,as well as dilatancy angles are explored.Elongated and oblate ellipsoids with varying aspect ratios are investigated for the occurrence of stick-slips.In addition,it is demonstrated that the initial arrangement direction has a significant impact on the coordination number and contact force chains.The corresponding anisotropy coefficients of the entire contact network are analyzed to probe the microscopic roots of macroscopic behavior. | Weichen Sun Kai Wu Songyu Liu Xiang Zhang | 2022 | Particuology2022，，11： | 0 |
| 18 | Identification and validation of a major gene for kernel length at the P1 locus in Triticum polonicum显示文摘Kernel size, one of the traits that determine wheat yield, is controlled by multiple quantitative trait loci.Polish wheat(Triticum polonicum) has elongated and plump kernel and is a valuable material for breeding high-yielding wheat cultivars. However, genes or loci determining kernel length(KL) in Polish wheat are unknown. We identified and validated a major KL gene, KL-PW, at the P1 locus in Polish wheat. KL-PW is VRT-A2, which encodes a MIKC-type MADS-box protein(MADS55). An insertion/deletion mutation in intron 1 of VRT-A2;led to an alternatively spliced transcript, VRT-A2;. Quantitative PCR analysis showed that VRT-A2;was more highly expressed in developing seeds than was VRT-A2 Ailanmai.Brassinosteroid(BR) sensitivity experiment and the expression of BR-related genes indicated that VRTA2;functions as a positive regulator of BR responses. VRT-A2;significantly increased KL of wheat.These findings not only reveal the molecular basis of KL-PW in controlling KL, but also provide a valuable genetic resource for increasing kernel size in wheat. | Songyue Chai Qin Yao Rui Liu Wenhui Xiang Xue Xiao Xing Fan Jian Zeng Lina Sha Houyang Kang Haiqin Zhang Dan Long Dandan Wu Yonghong Zhou Yi Wang | 2022 | The Crop Journal2022，10，2： | 0 |
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