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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Yttrium-90 microspheres for the treatment of hepatocellular carcinoma显示文摘 | Jean Francois H. Geschwind Riad Salem Brian I. Carr Michael C. Soulen Kenneth G. Thurston Kathleen A. Goin Mark van Buskirk Carol A. Roberts James E. Goin | 2004 | Gastroenterology2004，，： | 2 |
| 3 | The Reaction of a Phosphorus Ylide with Aroyl Cyanides显示文摘 | Soulen R L Carlson S D Lang F | 1973 | J Org Chem1973，38，3： | 1 |
| 4 | Minimally invasive treatmentof malignant hepatic tumors: at the threshold of a major break-through 显示文摘 | Dodd GD Soulen MC Kane RA | 2000 | Radiographics2000，20，1： | 1 |
| 5 | Elective embolization for prevention of hemorrhage from renal angiomyolipomas显示文摘 | Faykus MH Shlansky-Goldberg RD | 1994 | JVIR1994，5，： | 1 |
| 6 | Sutureless securement device reduces complications of peripherally inserted central venous catheters显示文摘 | Yamamoto AJ Solomon JA Soulen MC | 2002 | J Vasc Interv Radiol2002，13，： | 1 |
| 7 | Minimally invasive treatment of malignant hepatic tumors:at the threshold of a major breakthrough显示文摘 | Dodd GD Soulen MC Kane RA | 2000 | Radiographics2000，20，1： | 1 |
| 8 | Renal angiomyolipoma:long-term results after arterial embollzation显示文摘 | Kothary N Soulen MC Clark TW | 2005 | J Vase Interv Radiol2005，16，1： | 1 |
| 9 | Sutureless se- curement device reduces complications of peripherally inserted central venous catheters 显示文摘 | Yamamoto AJ Solomon JA Soulen MC | 2002 | J Vasc Interv Radiol2002，13，1： | 1 |
| 10 | Society of interventional radiology position statement on chemoembolization of hepatic malignancies显示文摘 | Brown DB Geschwind JF Soulen MC | | 0，，： | 1 |
| 11 | Delivery of encapsulated Doxorubicin by ultrasound- mediated size reduction of drug-loaded polymer contrast agents 显示文摘 | Eisenbrey J R Soulen M C Wheatley M A | 2010 | IEEE Trans Biomed Eng2010，57，1： | 1 |
| 12 | Liver transplantation for hepatocellular carcinoma validation of present selection criteria in predicting outcome显示文摘 | Kirti Shetty Kate Timmins Colleen Brensinger Emma E. Furth Sushil Rattan Weijing Sun Mark Rosen Michael Soulen Abraham Shaked K. Rajender Reddy Kim M. Olthoff | 2004 | Liver Transpl2004，，7： | 1 |
| 13 | Minimally invasive treat-ment of malignant hepatic tumors at the threshold of a major break through显示文摘 | Dodd GD 3rd Soulen MC Kane RA | 2000 | Raidiographics2000，20，： | 1 |
| 14 | Sutureless secure-ment device reduces complications of peripherally insertedcentral venous catheters 显示文摘 | Yamamoto AJ Solomon JA Soulen MC | 2002 | Vase Interv Radiol2002，13，1： | 1 |
| 15 | Milk of calcium fluid collectionsin juvenile dermatomyositis: MRI characteristics 显示文摘 | Samson C Soulen RL Gursel E | 2000 | PediatrRadiol2000，30，1： | 1 |
| 16 | FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation 显示文摘 | Anderson G S Brinkmann F Soulen M C | 2003 | Clin Nucl Med2003，281，： | 1 |
| 17 | Life-threatening pulmonary emboli and cor pulmonale: treatment with percutaneous pulmonary artery stent placement显示文摘 | Haskal Z J Soulen M C Huetti E A | 1994 | Radiology1994，191，： | 1 |
| 18 | Society of interventional radiology position statement on chemoembolization of hepatic malignancies显示文摘 | Brown DB Geschwind JF Soulen MC | 2006 | J Vasc Interv Radiol2006，20，： | 1 |
| 19 | FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation 显示文摘 | Anderson GS Brinkmann F Soulen MC | 2003 | Clin Nucl Med2003，28，3： | 1 |
| 20 | Sutureless securement device reduces complications of peripherally inserted central venous catheters 显示文摘 | Yamamoto AJ Solomon JA Soulen MC | 2002 | J Vasc Interv Radiol2002，13，1： | 1 |
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